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The map label for this gene is irgA [H]

Identifier: 74316457

GI number: 74316457

Start: 459526

End: 461538

Strand: Direct

Name: irgA [H]

Synonym: Tbd_0439

Alternate gene names: 74316457

Gene position: 459526-461538 (Clockwise)

Preceding gene: 74316456

Following gene: 74316458

Centisome position: 15.79

GC content: 64.88

Gene sequence:

>2013_bases
GTGGACAGCACGAGGCTTGCCGGCGTTTGGTTGATCGGGACATTGCTTCTCGGTCAGGGTAGTGCGTTCGCGCAGGTCGA
TGAAGCCGATTTCTTCGACGAACTGCCTGTCGTGCTGTCGGCGTCGCGCCTGTCGCAGCCCGTGAGCGACGCCCCCACCG
CGGTGAGCGTCATCGATCAAGAGATGATTCGGGCGTCGGGGTTTCGCGACATCCCCGAGTTGCTGCGCCTGGTGCCGGGT
TTTTCGGTCGCTTACACCGAGGACAACACCTGGACCGCGGGCTACCACGGGCTCGCCGACGCCTATTCGCGGCGCTTTCA
GGTGCTGGTCGACGGGCGCTCGATATACAGTCCGCACTACGGCGCGGTTTACTGGACCGACCTGCCGCTCTCGATCGACG
ACATCGAGCGCATCGAGGTCGTGCGCGGCCCCAATGCGGCGATTTACGGCGCGAACGCTTTTGTCGCCGTCATCAACATC
ATCACCAAGGCGGCTGCGCAGGTTCCGGGCGCCTTCGTGTCCATGCAGGCCGGCGAGCAGGACATGCGCGGGATCACGGT
GCGCCAGGGCGGCGGAAGCGGCGACCTGCGCTACCGGCTTACGGCCTCTGCGCAGCAGCGCGACCGCTTCGAGCGTGACG
TGGTAGGCAAGCTCGATCCAGAAGGCCCACTTTCCGACGACAACGGGCGCTACTTCGAGGCGAGCAGGACCTATTTCGTC
AACGGCCGCGTCGATCGGCAAATCACGAGGGATTCTGACCTGATGCTGCAGTTCGGCCTCTCGCGCGGTGACTGGAAAGG
CGGCTCGCGTACCGCCGCGCCCGGGTCCGTGCTCGAACCGATCGACCAGGATTCGCGCGCACTTTACCTGCAACTGGCTT
ATCACAAGGTCGAGTCCGAGCGGCGCGAGTGGCGGCTCCAGGCCTACCACAGCCAGAACCGGTTCGACGCCGACGCCGCC
GGAGACGTCGGCGTAAACGTGGTCGTGGACCAGTATCTGACCCAGTCGCGCAGCAACATCGAGCTGCAGGTGACCGAGCA
GTGGACGCCGACCTTGCGCGCCGTCTGGGGCGGCGAAGTCCGCCAGGAGTCGGTCAAGAGCCCCCAGGGTTACAACTCGG
ACAGGACGCTGCGCGGCGAATTGGCGCGCAGCTTTGCGAACCTGGAATGGCGGGCGACCGGGCGCCTGCTGGTTCAGGGC
GGCGCGATGCTCGAACACCACTACTTCACCGGCACCGACGTCTCCCCGCGCGTGGCGGCGAACTTTACCTTGGCGCCCGG
GCACGTGCTCCGCCTTGGTATTTCCCAGGCCTATCGCTCGCCCACGTTTTTCGAGCAGGAGGGTAATCAGGTCATTGTCC
TCGACGACGGCACGGTCGGCGACGTGGTGACGGTGCCTTCGCCGCGCCTCGCGCCCGAACGCATACTGTCGCGCGAGATT
GGCTATGTCGGTTATTGGCGCCCCGCCCGGCTGGAGTTCGATCTGCGCGTGTTCCGGGACAAGATCGGAAATTTCATCGG
CCAGCAAAAGAGCGATTTCTTTAGCGGCGATGCCATCCGGGTCAACGAGTTCAGATACGAGAACATCGGCCAGGCGTGGT
CCCAAGGGGGCGAATTTCAACTGCGCTGGAAGCCCGTCCGACGACTGGATGTCCACGCGCACTTCGCCCGCGTCTTCACG
ACCGCGGACACACGGCGGGAAAACTACACCGTGGACATTCCGCTCTCCACTCCGCGCAGTTCCTGGGGTGTGCTGGCCAC
CTACCGGTTCGACAACGGGTGGGAGACGAGCGGCGGGGTCTGGGGAACCGACGCCGTGAAGTGGCTCACCGAGGGAGACA
CTACCCGGCGCTATACGCGCGTCGATGCCCGTCTTGCGAAACGCTGGAAGTGGCAGGGTCGCGAGGTGGAGGCTGCCTTG
GTCGGCCAGAATCTCGGCGACGACTACGAGGAGTTTCGCGACACCAACCGCTTCAGCCGTCGCGTCTACGGCAGCCTCGC
TTTGGCATGGTAG

Upstream 100 bases:

>100_bases
CATGGACGACGATATTCCGTTCTGATCCCATCCCGCAGGGCCGGCGCACCACGGCGCATACAACGATAACGCGGGGAGAG
CGCACATCGCGCAGAAGAAA

Downstream 100 bases:

>100_bases
CCGCCGAGGGCGCAGCCCTGCGGCCCCGCATCTTGGGGACTTGCGGGCTGGCGAGTATAATTTGCGCAACTTCTTGATTG
TCGGAGAATTTTCATGCCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MDSTRLAGVWLIGTLLLGQGSAFAQVDEADFFDELPVVLSASRLSQPVSDAPTAVSVIDQEMIRASGFRDIPELLRLVPG
FSVAYTEDNTWTAGYHGLADAYSRRFQVLVDGRSIYSPHYGAVYWTDLPLSIDDIERIEVVRGPNAAIYGANAFVAVINI
ITKAAAQVPGAFVSMQAGEQDMRGITVRQGGGSGDLRYRLTASAQQRDRFERDVVGKLDPEGPLSDDNGRYFEASRTYFV
NGRVDRQITRDSDLMLQFGLSRGDWKGGSRTAAPGSVLEPIDQDSRALYLQLAYHKVESERREWRLQAYHSQNRFDADAA
GDVGVNVVVDQYLTQSRSNIELQVTEQWTPTLRAVWGGEVRQESVKSPQGYNSDRTLRGELARSFANLEWRATGRLLVQG
GAMLEHHYFTGTDVSPRVAANFTLAPGHVLRLGISQAYRSPTFFEQEGNQVIVLDDGTVGDVVTVPSPRLAPERILSREI
GYVGYWRPARLEFDLRVFRDKIGNFIGQQKSDFFSGDAIRVNEFRYENIGQAWSQGGEFQLRWKPVRRLDVHAHFARVFT
TADTRRENYTVDIPLSTPRSSWGVLATYRFDNGWETSGGVWGTDAVKWLTEGDTTRRYTRVDARLAKRWKWQGREVEAAL
VGQNLGDDYEEFRDTNRFSRRVYGSLALAW

Sequences:

>Translated_670_residues
MDSTRLAGVWLIGTLLLGQGSAFAQVDEADFFDELPVVLSASRLSQPVSDAPTAVSVIDQEMIRASGFRDIPELLRLVPG
FSVAYTEDNTWTAGYHGLADAYSRRFQVLVDGRSIYSPHYGAVYWTDLPLSIDDIERIEVVRGPNAAIYGANAFVAVINI
ITKAAAQVPGAFVSMQAGEQDMRGITVRQGGGSGDLRYRLTASAQQRDRFERDVVGKLDPEGPLSDDNGRYFEASRTYFV
NGRVDRQITRDSDLMLQFGLSRGDWKGGSRTAAPGSVLEPIDQDSRALYLQLAYHKVESERREWRLQAYHSQNRFDADAA
GDVGVNVVVDQYLTQSRSNIELQVTEQWTPTLRAVWGGEVRQESVKSPQGYNSDRTLRGELARSFANLEWRATGRLLVQG
GAMLEHHYFTGTDVSPRVAANFTLAPGHVLRLGISQAYRSPTFFEQEGNQVIVLDDGTVGDVVTVPSPRLAPERILSREI
GYVGYWRPARLEFDLRVFRDKIGNFIGQQKSDFFSGDAIRVNEFRYENIGQAWSQGGEFQLRWKPVRRLDVHAHFARVFT
TADTRRENYTVDIPLSTPRSSWGVLATYRFDNGWETSGGVWGTDAVKWLTEGDTTRRYTRVDARLAKRWKWQGREVEAAL
VGQNLGDDYEEFRDTNRFSRRVYGSLALAW
>Mature_670_residues
MDSTRLAGVWLIGTLLLGQGSAFAQVDEADFFDELPVVLSASRLSQPVSDAPTAVSVIDQEMIRASGFRDIPELLRLVPG
FSVAYTEDNTWTAGYHGLADAYSRRFQVLVDGRSIYSPHYGAVYWTDLPLSIDDIERIEVVRGPNAAIYGANAFVAVINI
ITKAAAQVPGAFVSMQAGEQDMRGITVRQGGGSGDLRYRLTASAQQRDRFERDVVGKLDPEGPLSDDNGRYFEASRTYFV
NGRVDRQITRDSDLMLQFGLSRGDWKGGSRTAAPGSVLEPIDQDSRALYLQLAYHKVESERREWRLQAYHSQNRFDADAA
GDVGVNVVVDQYLTQSRSNIELQVTEQWTPTLRAVWGGEVRQESVKSPQGYNSDRTLRGELARSFANLEWRATGRLLVQG
GAMLEHHYFTGTDVSPRVAANFTLAPGHVLRLGISQAYRSPTFFEQEGNQVIVLDDGTVGDVVTVPSPRLAPERILSREI
GYVGYWRPARLEFDLRVFRDKIGNFIGQQKSDFFSGDAIRVNEFRYENIGQAWSQGGEFQLRWKPVRRLDVHAHFARVFT
TADTRRENYTVDIPLSTPRSSWGVLATYRFDNGWETSGGVWGTDAVKWLTEGDTTRRYTRVDARLAKRWKWQGREVEAAL
VGQNLGDDYEEFRDTNRFSRRVYGSLALAW

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=151, Percent_Identity=35.7615894039735, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 75297; Mature: 75297

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTRLAGVWLIGTLLLGQGSAFAQVDEADFFDELPVVLSASRLSQPVSDAPTAVSVIDQ
CCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHH
EMIRASGFRDIPELLRLVPGFSVAYTEDNTWTAGYHGLADAYSRRFQVLVDGRSIYSPHY
HHHHHCCCCCHHHHHHHCCCCEEEEECCCCEECCCCHHHHHHCCEEEEEECCCEECCCCC
GAVYWTDLPLSIDDIERIEVVRGPNAAIYGANAFVAVINIITKAAAQVPGAFVSMQAGEQ
CEEEEEECCCCCCCHHEEEEEECCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCC
DMRGITVRQGGGSGDLRYRLTASAQQRDRFERDVVGKLDPEGPLSDDNGRYFEASRTYFV
CCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCEEEE
NGRVDRQITRDSDLMLQFGLSRGDWKGGSRTAAPGSVLEPIDQDSRALYLQLAYHKVESE
CCCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEHHHHHHHH
RREWRLQAYHSQNRFDADAAGDVGVNVVVDQYLTQSRSNIELQVTEQWTPTLRAVWGGEV
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCHH
RQESVKSPQGYNSDRTLRGELARSFANLEWRATGRLLVQGGAMLEHHYFTGTDVSPRVAA
HHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEECCEEEEECCCEEEEEEECCCCCCCCEEE
NFTLAPGHVLRLGISQAYRSPTFFEQEGNQVIVLDDGTVGDVVTVPSPRLAPERILSREI
EEEECCCHHEEEEHHHHHCCCCCEECCCCEEEEECCCCCCCEEECCCCCCCHHHHHHHHC
GYVGYWRPARLEFDLRVFRDKIGNFIGQQKSDFFSGDAIRVNEFRYENIGQAWSQGGEFQ
CCEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCEE
LRWKPVRRLDVHAHFARVFTTADTRRENYTVDIPLSTPRSSWGVLATYRFDNGWETSGGV
EEEECCCEEEHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCC
WGTDAVKWLTEGDTTRRYTRVDARLAKRWKWQGREVEAALVGQNLGDDYEEFRDTNRFSR
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
RVYGSLALAW
HHHHEEEECC
>Mature Secondary Structure
MDSTRLAGVWLIGTLLLGQGSAFAQVDEADFFDELPVVLSASRLSQPVSDAPTAVSVIDQ
CCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHH
EMIRASGFRDIPELLRLVPGFSVAYTEDNTWTAGYHGLADAYSRRFQVLVDGRSIYSPHY
HHHHHCCCCCHHHHHHHCCCCEEEEECCCCEECCCCHHHHHHCCEEEEEECCCEECCCCC
GAVYWTDLPLSIDDIERIEVVRGPNAAIYGANAFVAVINIITKAAAQVPGAFVSMQAGEQ
CEEEEEECCCCCCCHHEEEEEECCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCC
DMRGITVRQGGGSGDLRYRLTASAQQRDRFERDVVGKLDPEGPLSDDNGRYFEASRTYFV
CCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCEEEE
NGRVDRQITRDSDLMLQFGLSRGDWKGGSRTAAPGSVLEPIDQDSRALYLQLAYHKVESE
CCCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEHHHHHHHH
RREWRLQAYHSQNRFDADAAGDVGVNVVVDQYLTQSRSNIELQVTEQWTPTLRAVWGGEV
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCHH
RQESVKSPQGYNSDRTLRGELARSFANLEWRATGRLLVQGGAMLEHHYFTGTDVSPRVAA
HHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEECCEEEEECCCEEEEEEECCCCCCCCEEE
NFTLAPGHVLRLGISQAYRSPTFFEQEGNQVIVLDDGTVGDVVTVPSPRLAPERILSREI
EEEECCCHHEEEEHHHHHCCCCCEECCCCEEEEECCCCCCCEEECCCCCCCHHHHHHHHC
GYVGYWRPARLEFDLRVFRDKIGNFIGQQKSDFFSGDAIRVNEFRYENIGQAWSQGGEFQ
CCEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCEE
LRWKPVRRLDVHAHFARVFTTADTRRENYTVDIPLSTPRSSWGVLATYRFDNGWETSGGV
EEEECCCEEEHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCC
WGTDAVKWLTEGDTTRRYTRVDARLAKRWKWQGREVEAALVGQNLGDDYEEFRDTNRFSR
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
RVYGSLALAW
HHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]