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The map label for this gene is ssb [H]

Identifier: 74316456

GI number: 74316456

Start: 458977

End: 459450

Strand: Direct

Name: ssb [H]

Synonym: Tbd_0438

Alternate gene names: 74316456

Gene position: 458977-459450 (Clockwise)

Preceding gene: 74316455

Following gene: 74316457

Centisome position: 15.77

GC content: 64.98

Gene sequence:

>474_bases
ATGGCATCCGTCAACAAAGTCATCCTGGTCGGCAATCTCGGACGCGACCCCGAGATGCGCTACCTGCCGAGCGGAGAGGC
CGTCGCCAACCTCGCGATCGCGACGACCGACAAATACAAGGACAAGAGCGGCCAGATGGTCGAGCAGACCGAGTGGCACC
GCGTCAGTTTCTTCGGCCGTACCGCCGAGGTGTGCGGGCAGTACCTGAAAAAGGGTTCGCAGGTCTACGTCGAAGGCTCG
ATCCGCACGCGCAAGTACACCGACAAGGAAGGCGTCGAGAAATACGCGACCGAGATCCGCGGCGACCGGATGCAGATGCT
GGGTAGCCGCAGCGGTGGCGGGGGTGTGGCCGACATGGACGACGGCTTCAACCAGGCGCCGCAGCGCAGCCAGCCGCGTG
GCAACGCCCCCGCCGGCTCGCAGCGCCCGGCGAGCAGCGGATTCGACGACATGGACGACGATATTCCGTTCTGA

Upstream 100 bases:

>100_bases
GGCGCGCGGAGCCTGCTGGAAGCGGCCACCGCCTGAAAGCCGGCCTGATAGAATTCGCAGGGCCCAAGCGCGCACAATCC
AACTCATCACGGGGAAAAAC

Downstream 100 bases:

>100_bases
TCCCATCCCGCAGGGCCGGCGCACCACGGCGCATACAACGATAACGCGGGGAGAGCGCACATCGCGCAGAAGAAAGTGGA
CAGCACGAGGCTTGCCGGCG

Product: single-strand binding protein

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MASVNKVILVGNLGRDPEMRYLPSGEAVANLAIATTDKYKDKSGQMVEQTEWHRVSFFGRTAEVCGQYLKKGSQVYVEGS
IRTRKYTDKEGVEKYATEIRGDRMQMLGSRSGGGGVADMDDGFNQAPQRSQPRGNAPAGSQRPASSGFDDMDDDIPF

Sequences:

>Translated_157_residues
MASVNKVILVGNLGRDPEMRYLPSGEAVANLAIATTDKYKDKSGQMVEQTEWHRVSFFGRTAEVCGQYLKKGSQVYVEGS
IRTRKYTDKEGVEKYATEIRGDRMQMLGSRSGGGGVADMDDGFNQAPQRSQPRGNAPAGSQRPASSGFDDMDDDIPF
>Mature_156_residues
ASVNKVILVGNLGRDPEMRYLPSGEAVANLAIATTDKYKDKSGQMVEQTEWHRVSFFGRTAEVCGQYLKKGSQVYVEGSI
RTRKYTDKEGVEKYATEIRGDRMQMLGSRSGGGGVADMDDGFNQAPQRSQPRGNAPAGSQRPASSGFDDMDDDIPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=116, Percent_Identity=33.6206896551724, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1790494, Length=182, Percent_Identity=49.4505494505495, Blast_Score=158, Evalue=2e-40,
Organism=Drosophila melanogaster, GI85725234, Length=101, Percent_Identity=34.6534653465347, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647376, Length=101, Percent_Identity=34.6534653465347, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 17192; Mature: 17061

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVNKVILVGNLGRDPEMRYLPSGEAVANLAIATTDKYKDKSGQMVEQTEWHRVSFFGR
CCCCCEEEEEECCCCCCCCEECCCCHHHHEEEEECCCCCCCCCCCCCCCCCCEEHHHCCC
TAEVCGQYLKKGSQVYVEGSIRTRKYTDKEGVEKYATEIRGDRMQMLGSRSGGGGVADMD
HHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC
DGFNQAPQRSQPRGNAPAGSQRPASSGFDDMDDDIPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASVNKVILVGNLGRDPEMRYLPSGEAVANLAIATTDKYKDKSGQMVEQTEWHRVSFFGR
CCCCEEEEEECCCCCCCCEECCCCHHHHEEEEECCCCCCCCCCCCCCCCCCEEHHHCCC
TAEVCGQYLKKGSQVYVEGSIRTRKYTDKEGVEKYATEIRGDRMQMLGSRSGGGGVADMD
HHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC
DGFNQAPQRSQPRGNAPAGSQRPASSGFDDMDDDIPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]