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The map label for this gene is coaD

Identifier: 74316398

GI number: 74316398

Start: 408401

End: 408883

Strand: Direct

Name: coaD

Synonym: Tbd_0380

Alternate gene names: 74316398

Gene position: 408401-408883 (Clockwise)

Preceding gene: 74316397

Following gene: 74316399

Centisome position: 14.04

GC content: 64.18

Gene sequence:

>483_bases
ATGCTGACCGCCGTCTATCCAGGCACCTTCGACCCCATCACGCGCGGCCACGAGGACCTCGTGCGACGCGCCGTCCGCCT
CTTCGACCGCGTCGTCGTCGCGGTCGCGGAGTCGAGGAACAAACGCCCGTTCTTCAGCATGGACGAGCGTGTCGCGATGA
CACGCGAAGTCCTCGCCGACGTGCCGCAGGTCCGGGTCGAGGGCTTCTCGGGGCTTCTGATCGACTTCGTCGCCGAGCAG
GGCGCGATCGCCGTGCTCCGCGGTTTGCGCGCCGCGTCGGACTTCGAATACGAGTTCCAGCTCGCGGGGATGAACCGGAA
CCTGAAGCCGGACATCGAGACGCTGTTCCTGACCCCGTCCGAGCAATACATGTTCATCTCGGCGAGCATGATCCGCGAGA
TCGCGCAGTTCGGCGGCGACGTCACGCCCTTCGTTCACCCGTTGGTCGCGCGGCGATTAAGTGAGAAAATAAGAGAAAAC
TGA

Upstream 100 bases:

>100_bases
TCGAGCAGGGGGCGGAGACGGCCGTTCCGCCGGGGTTCGTCGTCCACCGCAGCGGGCGCGCCGGACGTTCGCATTTCGCG
CTGCTCATGAAGGAATAGCG

Downstream 100 bases:

>100_bases
TTTAGTCGGAGAATGCGATGGCCCTGATGATCACGGACGAGTGCATCAATTGCGACGTCTGTCTGCCGGAATGCCCCAAC
GAAGCGATTTCTCAGGGTGA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MLTAVYPGTFDPITRGHEDLVRRAVRLFDRVVVAVAESRNKRPFFSMDERVAMTREVLADVPQVRVEGFSGLLIDFVAEQ
GAIAVLRGLRAASDFEYEFQLAGMNRNLKPDIETLFLTPSEQYMFISASMIREIAQFGGDVTPFVHPLVARRLSEKIREN

Sequences:

>Translated_160_residues
MLTAVYPGTFDPITRGHEDLVRRAVRLFDRVVVAVAESRNKRPFFSMDERVAMTREVLADVPQVRVEGFSGLLIDFVAEQ
GAIAVLRGLRAASDFEYEFQLAGMNRNLKPDIETLFLTPSEQYMFISASMIREIAQFGGDVTPFVHPLVARRLSEKIREN
>Mature_160_residues
MLTAVYPGTFDPITRGHEDLVRRAVRLFDRVVVAVAESRNKRPFFSMDERVAMTREVLADVPQVRVEGFSGLLIDFVAEQ
GAIAVLRGLRAASDFEYEFQLAGMNRNLKPDIETLFLTPSEQYMFISASMIREIAQFGGDVTPFVHPLVARRLSEKIREN

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=154, Percent_Identity=49.3506493506493, Blast_Score=168, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_THIDA (Q3SLS2)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314138.1
- HSSP:   Q9WZK0
- ProteinModelPortal:   Q3SLS2
- SMR:   Q3SLS2
- STRING:   Q3SLS2
- GeneID:   3672767
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0380
- NMPDR:   fig|292415.3.peg.774
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q3SLS2
- BioCyc:   TDEN292415:TBD_0380-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18122; Mature: 18122

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAVYPGTFDPITRGHEDLVRRAVRLFDRVVVAVAESRNKRPFFSMDERVAMTREVLAD
CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
VPQVRVEGFSGLLIDFVAEQGAIAVLRGLRAASDFEYEFQLAGMNRNLKPDIETLFLTPS
CHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCC
EQYMFISASMIREIAQFGGDVTPFVHPLVARRLSEKIREN
CCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTAVYPGTFDPITRGHEDLVRRAVRLFDRVVVAVAESRNKRPFFSMDERVAMTREVLAD
CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
VPQVRVEGFSGLLIDFVAEQGAIAVLRGLRAASDFEYEFQLAGMNRNLKPDIETLFLTPS
CHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCC
EQYMFISASMIREIAQFGGDVTPFVHPLVARRLSEKIREN
CCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA