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The map label for this gene is metH [H]

Identifier: 74316252

GI number: 74316252

Start: 255446

End: 259159

Strand: Reverse

Name: metH [H]

Synonym: Tbd_0234

Alternate gene names: 74316252

Gene position: 259159-255446 (Counterclockwise)

Preceding gene: 74316254

Following gene: 74316247

Centisome position: 8.91

GC content: 65.24

Gene sequence:

>3714_bases
ATGCGCGATTGCCCTGCCAGCCTCACGACCATGTCCCGCACCGACCTGCTGCATTCCCTGCTCGCCCAGCGCATCCTCGT
CCTCGACGGCGCGATGGGAACGATGATCCAGTCGTACAAGCTCGGCGAGGCGGACTACCGGGGTGAGCGCTTTGCCGATT
TTGCCCACGACCTCAAGGGCAACAACGACCTGCTATGCCTGACGCAGCCCGCGATCATCAAGGAAATCCACGCCAAGTAC
CTCGCGGCCGGCGCCGACATCCTCGAGACCAACAGCTTCAACGCGACCGCGATCTCGATGGCCGACTACCGTATGGAGCA
CCTGGTGCCGGAGCTCAACTTCGCCGCCGCCAAACTCGCGCGCGAAGCCGCCGACGAGGCGACCGCGCAGAACCCGGCCA
AGCCGCGCTTCGTCGCCGGCGTGCTCGGGCCGACGTCACGCACGGCGACGATCTCGCCCGACGTCAACGACCCGGGCTTC
CGCAATGTTACGTTCGACCAACTGCGCGAAGCCTACCTCGAGGCGATCGACGGCCTGGTCAAGGGTGGCGCCGACATCCT
GATGGTCGAGACGATTTTCGATACGCTCAACGCCAAGGCTGCGCTGTTCGCGATCGAGGAATATTTCGAGATCAATAACA
TGCGACTGCCCGTGATGATCTCGGGCACGATCACCGACGCGTCCGGCCGCACGCTCTCTGGCCAGACCGGCGAAGCGTTC
TGGAATTCGGTGCGCCACGCGCGCCCGCTGTCGATCGGCCTGAACTGCGCGCTTGGGCCGGATCTCTTGCGGCAATACGT
CGAAGAACTATCGAACAAGGCCGAGGTCTTCATCTCGGCCCACCCCAACGCCGGCCTGCCCAACGCCTTCGGTGAATACG
ACATGGACGGCGCCGAAATGGCGAAGCACATCGGCGAGTGGGCACGCGCTGGGCTGCTCAACATCGTCGGCGGCTGCTGC
GGCACCTCGCCTTCGCACATTGCGGCCATCGCCAAGGCCGTCGAGGGCGTCGCGCCGCGCGTGCCGCCCGTGCTCGAGCC
GGCGATGCGCCTGTCGGGGCTCGAGCCGTTCAACGTTGGGAAAGATTCGCTCTTCGTCAACGTCGGCGAGCGCACCAACG
TCACCGGCTCCAAGGCCTTCGCGCGGATGATCCTCGAAGGCCGCTATGACGACGCCTTGTCGGTGGCGCGCCAGCAGGTC
GAGAACGGCGCCCAGGTGATCGACATCAACATGGACGAGGGCATGCTCGACGCCGAGGCGGCGATGGTGCGCTTCCTCCA
TCTCATTGCCTCGGAGCCCGATATCGCGCGGGTGCCGATCATGATCGACTCGTCGAAGTGGAACGTCATCGAGGCCGGCC
TGAAGTGCATCCAGGGCAAGGGCATCGTTAATTCAATTTCCATGAAGGAAGGCGAAGCCGAATTCATCGAGCGGGCGAAG
CTGTGCCTGCGCTACGGCGCAGCGGTAATCGTGATGGCCTTCGACGAGACCGGCCAGGCCGACACCTATGCGCGCAAGAC
CGAGATCTGCACCCGCGCCTACAAGCTCTTGACCGAGACGGTCGGCTTCCCGGCCGAGGACATCATCTTCGACCCCAACA
TCTTCGCGGTTGCGACCGGCATCGAGGAGCACGCCAACTACGCTGTTGATTTTATTGAAGCCACGCGCTGGATCCGCCAG
AACCTGCCGTATGCGCACGTCTCTGGCGGGGTGTCGAACGTGAGCTTCTCGTTCCGCGGCAACGACGCGGTGCGCGAGGC
GATCCACACCGCCTTCCTCTACCACGCGATCCAGGCCGGCATGGACATGGGCATCGTCAACGCCGGCCAGCTCGGCGTCT
ATGAGAACCTCGACCCGGAGCTGAAGGAACGCGTCGAGGACGTCTTGCTGAACCGCCGCGCCGACGCGACCGAGCGCCTC
GTCGCCTTCGCTGAAGGCGTGAAGGGCGGCGCCAAGGAGAAGGTCGAGGACCTCGCCTGGCGCAGCCTGCCAGTCAACGA
ACGGCTCACCCACGCGCTGGTCCAGGGCATCACCCAGTACATCGTCGAGGACACGGAAGCCGCCCGCCTCGAGGCCGAAC
GCCCACTGCACGTGATCGAAGGCCCGCTGATGGCCGGCATGAACGTCGTCGGCGACCTCTTCGGCGCCGGCAAGATGTTC
CTGCCGCAGGTCGTGAAGTCGGCGCGCGTAATGAAGCAGGCCGTCGCGCACCTGATCCCCTACATCGAGGCCGACAAGCG
CGCCGGCGATTCGCAGAGCGCAGGCAAGATCGTCATGGCGACGGTCAAGGGCGACGTCCACGACATCGGCAAAAACATCG
TCGGCGTCGTGCTCGGCTGCAACGGCTACGAAATCGTCGATCTGGGGGTCATGGTGCCGGCGCAGAAGATTCTCGACGCC
GCGCGCGAACACAAGGCCGACATCATCGGTCTCTCCGGCCTGATCACGCCCTCGCTCGAGGAAATGGCGCACGTGGCGAA
GGAAATGCAGCGCCAGGGCTTCACGATACCGCTCCTGATCGGCGGGGCGACGACGTCACTCGCGCACACGGCGGTCAAGA
TCGAGCCGAATTACGAGCACCCGGTGGTCTACGTGAAGGACGCGTCGCGCGCGGTCGGCGTGTGCACCCAATTGCTGTCG
GGCGAATTGCGCGACGCATTCGCGGCCGAGGTCCGTGCCGACTACGCGCAGACGCGCGCGCGCCACCTCAAGCACAAGTC
GGATACCGCCCGGCTGACGCTGGCCGATGCGCGCGCCAACAAGTTCGGCATCGACTGGGCGAGCTACACGCCGCCTGTTC
CGAACCAGCCCGGCGTGCATGTATTGAAGGCCTACGACCTGGCGAAACTGGTCGAGACGATCGACTGGACGCCGTTCTTC
GCGTCCTGGGAACTGCACGGAAAGTATCCGAAGATTCTCGACGACGAAGTGGTCGGCGCCGAGGCGACGAAGCTCTTCTC
CGATGCGCAGGCGATGCTGAACAGGATGGTCGCGGAGAACTGGGTCGAGGCGCGCGCGGTCTTCGGCCTCTTTCCCGCCA
ACGCCGTCGACGACGACATCGAGGTGTACGCCGATGAATCTCGCTCGCAAGCCCTGACCACGTGGCACAACCTGCGCCAG
CAGGCGAAGAAGCCCGAGGGTCGCGCCAACCTGTGTCTCGCCGACTTCGTCGCGCCGAAGGCGAGTGGGCTAAAGGATTA
TCTGGGCGCCTTCGTCGTGACCGCCGGCATCGGCGAGGACGAGCGGGCGAAGGCCTTCGAGGCCGCGCACGACGACTACT
CGGCGATCCTGTTCAAGTCGCTGTGCGACCGCCTGGCCGAAGCCTTCGCCGAGCACCTGCATCTGCGCGTGCGCCGGGAA
TTCTGGGGCTACGCCGCCGACGAAGCGCTGCCCAACGATGACCTGATCGCCGAGAAGTACCGCGGCATCCGTCCGGCGCC
CGGCTACCCGGCCTGCCCGGAGCACAGCGAGAAAGCGGCGCTCTTCGGACTGCTCGACGCGACGAACGCGATCGGCGTCG
AGTTGACGGAAAATTTCGCGATGTGGCCGGGCGCTGCCGTGTCGGGCTTCTACCTTTCGCACCCCGACAGCCAGTATTTC
GCGGTGGCGAAGATCGAGCGCGATCAGGTCGAGGACTACGCGCGGCGCAAGGGATGGGATGTGAAGACGGCGGAACGGTG
GCTGGGGCCGAACCTCGGCTACCAGCCGGAGTAA

Upstream 100 bases:

>100_bases
TAGGCGTAGGCTTCCTTGGGTTCGAGGTTTTTCATCGGACGATTCCGCGGCGCGATACTGCACCATAGCGCGTCGGAGGG
CCGCAGGCCAAGCGAATATA

Downstream 100 bases:

>100_bases
AGCACAGGCTTGTCAGCCCGCTTCTCCAGCGAACCGAACACGCATTTCGCTGGCGTTAAGGTCGTTGGCCGCCGGAATCT
GAGGACTGTAGGGAACCTGC

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1237; Mature: 1237

Protein sequence:

>1237_residues
MRDCPASLTTMSRTDLLHSLLAQRILVLDGAMGTMIQSYKLGEADYRGERFADFAHDLKGNNDLLCLTQPAIIKEIHAKY
LAAGADILETNSFNATAISMADYRMEHLVPELNFAAAKLAREAADEATAQNPAKPRFVAGVLGPTSRTATISPDVNDPGF
RNVTFDQLREAYLEAIDGLVKGGADILMVETIFDTLNAKAALFAIEEYFEINNMRLPVMISGTITDASGRTLSGQTGEAF
WNSVRHARPLSIGLNCALGPDLLRQYVEELSNKAEVFISAHPNAGLPNAFGEYDMDGAEMAKHIGEWARAGLLNIVGGCC
GTSPSHIAAIAKAVEGVAPRVPPVLEPAMRLSGLEPFNVGKDSLFVNVGERTNVTGSKAFARMILEGRYDDALSVARQQV
ENGAQVIDINMDEGMLDAEAAMVRFLHLIASEPDIARVPIMIDSSKWNVIEAGLKCIQGKGIVNSISMKEGEAEFIERAK
LCLRYGAAVIVMAFDETGQADTYARKTEICTRAYKLLTETVGFPAEDIIFDPNIFAVATGIEEHANYAVDFIEATRWIRQ
NLPYAHVSGGVSNVSFSFRGNDAVREAIHTAFLYHAIQAGMDMGIVNAGQLGVYENLDPELKERVEDVLLNRRADATERL
VAFAEGVKGGAKEKVEDLAWRSLPVNERLTHALVQGITQYIVEDTEAARLEAERPLHVIEGPLMAGMNVVGDLFGAGKMF
LPQVVKSARVMKQAVAHLIPYIEADKRAGDSQSAGKIVMATVKGDVHDIGKNIVGVVLGCNGYEIVDLGVMVPAQKILDA
AREHKADIIGLSGLITPSLEEMAHVAKEMQRQGFTIPLLIGGATTSLAHTAVKIEPNYEHPVVYVKDASRAVGVCTQLLS
GELRDAFAAEVRADYAQTRARHLKHKSDTARLTLADARANKFGIDWASYTPPVPNQPGVHVLKAYDLAKLVETIDWTPFF
ASWELHGKYPKILDDEVVGAEATKLFSDAQAMLNRMVAENWVEARAVFGLFPANAVDDDIEVYADESRSQALTTWHNLRQ
QAKKPEGRANLCLADFVAPKASGLKDYLGAFVVTAGIGEDERAKAFEAAHDDYSAILFKSLCDRLAEAFAEHLHLRVRRE
FWGYAADEALPNDDLIAEKYRGIRPAPGYPACPEHSEKAALFGLLDATNAIGVELTENFAMWPGAAVSGFYLSHPDSQYF
AVAKIERDQVEDYARRKGWDVKTAERWLGPNLGYQPE

Sequences:

>Translated_1237_residues
MRDCPASLTTMSRTDLLHSLLAQRILVLDGAMGTMIQSYKLGEADYRGERFADFAHDLKGNNDLLCLTQPAIIKEIHAKY
LAAGADILETNSFNATAISMADYRMEHLVPELNFAAAKLAREAADEATAQNPAKPRFVAGVLGPTSRTATISPDVNDPGF
RNVTFDQLREAYLEAIDGLVKGGADILMVETIFDTLNAKAALFAIEEYFEINNMRLPVMISGTITDASGRTLSGQTGEAF
WNSVRHARPLSIGLNCALGPDLLRQYVEELSNKAEVFISAHPNAGLPNAFGEYDMDGAEMAKHIGEWARAGLLNIVGGCC
GTSPSHIAAIAKAVEGVAPRVPPVLEPAMRLSGLEPFNVGKDSLFVNVGERTNVTGSKAFARMILEGRYDDALSVARQQV
ENGAQVIDINMDEGMLDAEAAMVRFLHLIASEPDIARVPIMIDSSKWNVIEAGLKCIQGKGIVNSISMKEGEAEFIERAK
LCLRYGAAVIVMAFDETGQADTYARKTEICTRAYKLLTETVGFPAEDIIFDPNIFAVATGIEEHANYAVDFIEATRWIRQ
NLPYAHVSGGVSNVSFSFRGNDAVREAIHTAFLYHAIQAGMDMGIVNAGQLGVYENLDPELKERVEDVLLNRRADATERL
VAFAEGVKGGAKEKVEDLAWRSLPVNERLTHALVQGITQYIVEDTEAARLEAERPLHVIEGPLMAGMNVVGDLFGAGKMF
LPQVVKSARVMKQAVAHLIPYIEADKRAGDSQSAGKIVMATVKGDVHDIGKNIVGVVLGCNGYEIVDLGVMVPAQKILDA
AREHKADIIGLSGLITPSLEEMAHVAKEMQRQGFTIPLLIGGATTSLAHTAVKIEPNYEHPVVYVKDASRAVGVCTQLLS
GELRDAFAAEVRADYAQTRARHLKHKSDTARLTLADARANKFGIDWASYTPPVPNQPGVHVLKAYDLAKLVETIDWTPFF
ASWELHGKYPKILDDEVVGAEATKLFSDAQAMLNRMVAENWVEARAVFGLFPANAVDDDIEVYADESRSQALTTWHNLRQ
QAKKPEGRANLCLADFVAPKASGLKDYLGAFVVTAGIGEDERAKAFEAAHDDYSAILFKSLCDRLAEAFAEHLHLRVRRE
FWGYAADEALPNDDLIAEKYRGIRPAPGYPACPEHSEKAALFGLLDATNAIGVELTENFAMWPGAAVSGFYLSHPDSQYF
AVAKIERDQVEDYARRKGWDVKTAERWLGPNLGYQPE
>Mature_1237_residues
MRDCPASLTTMSRTDLLHSLLAQRILVLDGAMGTMIQSYKLGEADYRGERFADFAHDLKGNNDLLCLTQPAIIKEIHAKY
LAAGADILETNSFNATAISMADYRMEHLVPELNFAAAKLAREAADEATAQNPAKPRFVAGVLGPTSRTATISPDVNDPGF
RNVTFDQLREAYLEAIDGLVKGGADILMVETIFDTLNAKAALFAIEEYFEINNMRLPVMISGTITDASGRTLSGQTGEAF
WNSVRHARPLSIGLNCALGPDLLRQYVEELSNKAEVFISAHPNAGLPNAFGEYDMDGAEMAKHIGEWARAGLLNIVGGCC
GTSPSHIAAIAKAVEGVAPRVPPVLEPAMRLSGLEPFNVGKDSLFVNVGERTNVTGSKAFARMILEGRYDDALSVARQQV
ENGAQVIDINMDEGMLDAEAAMVRFLHLIASEPDIARVPIMIDSSKWNVIEAGLKCIQGKGIVNSISMKEGEAEFIERAK
LCLRYGAAVIVMAFDETGQADTYARKTEICTRAYKLLTETVGFPAEDIIFDPNIFAVATGIEEHANYAVDFIEATRWIRQ
NLPYAHVSGGVSNVSFSFRGNDAVREAIHTAFLYHAIQAGMDMGIVNAGQLGVYENLDPELKERVEDVLLNRRADATERL
VAFAEGVKGGAKEKVEDLAWRSLPVNERLTHALVQGITQYIVEDTEAARLEAERPLHVIEGPLMAGMNVVGDLFGAGKMF
LPQVVKSARVMKQAVAHLIPYIEADKRAGDSQSAGKIVMATVKGDVHDIGKNIVGVVLGCNGYEIVDLGVMVPAQKILDA
AREHKADIIGLSGLITPSLEEMAHVAKEMQRQGFTIPLLIGGATTSLAHTAVKIEPNYEHPVVYVKDASRAVGVCTQLLS
GELRDAFAAEVRADYAQTRARHLKHKSDTARLTLADARANKFGIDWASYTPPVPNQPGVHVLKAYDLAKLVETIDWTPFF
ASWELHGKYPKILDDEVVGAEATKLFSDAQAMLNRMVAENWVEARAVFGLFPANAVDDDIEVYADESRSQALTTWHNLRQ
QAKKPEGRANLCLADFVAPKASGLKDYLGAFVVTAGIGEDERAKAFEAAHDDYSAILFKSLCDRLAEAFAEHLHLRVRRE
FWGYAADEALPNDDLIAEKYRGIRPAPGYPACPEHSEKAALFGLLDATNAIGVELTENFAMWPGAAVSGFYLSHPDSQYF
AVAKIERDQVEDYARRKGWDVKTAERWLGPNLGYQPE

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1255, Percent_Identity=54.9800796812749, Blast_Score=1382, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1229, Percent_Identity=67.9414157851912, Blast_Score=1687, Evalue=0.0,
Organism=Escherichia coli, GI1786456, Length=330, Percent_Identity=25.4545454545455, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17535405, Length=1249, Percent_Identity=54.2834267413931, Blast_Score=1326, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 135004; Mature: 135004

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDCPASLTTMSRTDLLHSLLAQRILVLDGAMGTMIQSYKLGEADYRGERFADFAHDLKG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
NNDLLCLTQPAIIKEIHAKYLAAGADILETNSFNATAISMADYRMEHLVPELNFAAAKLA
CCCEEEEECHHHHHHHHHHHHHCCCCCEECCCCCCEEEEHHHHHHHHHCCCCHHHHHHHH
REAADEATAQNPAKPRFVAGVLGPTSRTATISPDVNDPGFRNVTFDQLREAYLEAIDGLV
HHHHHHHHCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KGGADILMVETIFDTLNAKAALFAIEEYFEINNMRLPVMISGTITDASGRTLSGQTGEAF
HCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCEECCCCHHHH
WNSVRHARPLSIGLNCALGPDLLRQYVEELSNKAEVFISAHPNAGLPNAFGEYDMDGAEM
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHH
AKHIGEWARAGLLNIVGGCCGTSPSHIAAIAKAVEGVAPRVPPVLEPAMRLSGLEPFNVG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
KDSLFVNVGERTNVTGSKAFARMILEGRYDDALSVARQQVENGAQVIDINMDEGMLDAEA
CCCEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
AMVRFLHLIASEPDIARVPIMIDSSKWNVIEAGLKCIQGKGIVNSISMKEGEAEFIERAK
HHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHH
LCLRYGAAVIVMAFDETGQADTYARKTEICTRAYKLLTETVGFPAEDIIFDPNIFAVATG
HHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCEEEECC
IEEHANYAVDFIEATRWIRQNLPYAHVSGGVSNVSFSFRGNDAVREAIHTAFLYHAIQAG
HHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHC
MDMGIVNAGQLGVYENLDPELKERVEDVLLNRRADATERLVAFAEGVKGGAKEKVEDLAW
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
RSLPVNERLTHALVQGITQYIVEDTEAARLEAERPLHVIEGPLMAGMNVVGDLFGAGKMF
HCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCHHH
LPQVVKSARVMKQAVAHLIPYIEADKRAGDSQSAGKIVMATVKGDVHDIGKNIVGVVLGC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHCCHHEEEEECC
NGYEIVDLGVMVPAQKILDAAREHKADIIGLSGLITPSLEEMAHVAKEMQRQGFTIPLLI
CCCEEEEECHHCCHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEE
GGATTSLAHTAVKIEPNYEHPVVYVKDASRAVGVCTQLLSGELRDAFAAEVRADYAQTRA
CCCHHHHHEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHLKHKSDTARLTLADARANKFGIDWASYTPPVPNQPGVHVLKAYDLAKLVETIDWTPFF
HHHHCCCCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCE
ASWELHGKYPKILDDEVVGAEATKLFSDAQAMLNRMVAENWVEARAVFGLFPANAVDDDI
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCH
EVYADESRSQALTTWHNLRQQAKKPEGRANLCLADFVAPKASGLKDYLGAFVVTAGIGED
HEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHCCCCCCHHHHHHHHHHCCCCCCC
ERAKAFEAAHDDYSAILFKSLCDRLAEAFAEHLHLRVRREFWGYAADEALPNDDLIAEKY
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHH
RGIRPAPGYPACPEHSEKAALFGLLDATNAIGVELTENFAMWPGAAVSGFYLSHPDSQYF
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCHHCCCEECCCCCCEE
AVAKIERDQVEDYARRKGWDVKTAERWLGPNLGYQPE
EEEECCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRDCPASLTTMSRTDLLHSLLAQRILVLDGAMGTMIQSYKLGEADYRGERFADFAHDLKG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
NNDLLCLTQPAIIKEIHAKYLAAGADILETNSFNATAISMADYRMEHLVPELNFAAAKLA
CCCEEEEECHHHHHHHHHHHHHCCCCCEECCCCCCEEEEHHHHHHHHHCCCCHHHHHHHH
REAADEATAQNPAKPRFVAGVLGPTSRTATISPDVNDPGFRNVTFDQLREAYLEAIDGLV
HHHHHHHHCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KGGADILMVETIFDTLNAKAALFAIEEYFEINNMRLPVMISGTITDASGRTLSGQTGEAF
HCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCEECCCCHHHH
WNSVRHARPLSIGLNCALGPDLLRQYVEELSNKAEVFISAHPNAGLPNAFGEYDMDGAEM
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHH
AKHIGEWARAGLLNIVGGCCGTSPSHIAAIAKAVEGVAPRVPPVLEPAMRLSGLEPFNVG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
KDSLFVNVGERTNVTGSKAFARMILEGRYDDALSVARQQVENGAQVIDINMDEGMLDAEA
CCCEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
AMVRFLHLIASEPDIARVPIMIDSSKWNVIEAGLKCIQGKGIVNSISMKEGEAEFIERAK
HHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHH
LCLRYGAAVIVMAFDETGQADTYARKTEICTRAYKLLTETVGFPAEDIIFDPNIFAVATG
HHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCEEEECC
IEEHANYAVDFIEATRWIRQNLPYAHVSGGVSNVSFSFRGNDAVREAIHTAFLYHAIQAG
HHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHC
MDMGIVNAGQLGVYENLDPELKERVEDVLLNRRADATERLVAFAEGVKGGAKEKVEDLAW
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
RSLPVNERLTHALVQGITQYIVEDTEAARLEAERPLHVIEGPLMAGMNVVGDLFGAGKMF
HCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCHHH
LPQVVKSARVMKQAVAHLIPYIEADKRAGDSQSAGKIVMATVKGDVHDIGKNIVGVVLGC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHCCHHEEEEECC
NGYEIVDLGVMVPAQKILDAAREHKADIIGLSGLITPSLEEMAHVAKEMQRQGFTIPLLI
CCCEEEEECHHCCHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEE
GGATTSLAHTAVKIEPNYEHPVVYVKDASRAVGVCTQLLSGELRDAFAAEVRADYAQTRA
CCCHHHHHEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHLKHKSDTARLTLADARANKFGIDWASYTPPVPNQPGVHVLKAYDLAKLVETIDWTPFF
HHHHCCCCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCE
ASWELHGKYPKILDDEVVGAEATKLFSDAQAMLNRMVAENWVEARAVFGLFPANAVDDDI
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCH
EVYADESRSQALTTWHNLRQQAKKPEGRANLCLADFVAPKASGLKDYLGAFVVTAGIGED
HEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHCCCCCCHHHHHHHHHHCCCCCCC
ERAKAFEAAHDDYSAILFKSLCDRLAEAFAEHLHLRVRREFWGYAADEALPNDDLIAEKY
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHH
RGIRPAPGYPACPEHSEKAALFGLLDATNAIGVELTENFAMWPGAAVSGFYLSHPDSQYF
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCHHCCCEECCCCCCEE
AVAKIERDQVEDYARRKGWDVKTAERWLGPNLGYQPE
EEEECCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]