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The map label for this gene is tapC [H]

Identifier: 73542645

GI number: 73542645

Start: 3247163

End: 3248437

Strand: Direct

Name: tapC [H]

Synonym: Reut_A2961

Alternate gene names: 73542645

Gene position: 3247163-3248437 (Clockwise)

Preceding gene: 73542644

Following gene: 73542646

Centisome position: 85.31

GC content: 62.82

Gene sequence:

>1275_bases
ATGGCAACGCGCGCACCAGCTGCGAGCGCACGGGCGGCAGTGCCGCCACGCGCGAAGGCAGGACGAGCAGGACGTAAAGC
ACCCACGCAGTACATCTTCGAGTGGGAAGGCAAGGACCGCAAAGGCAAGACGTTCACCGGGGAACAGCGGGCCGAAAACC
AGGCCGAGGTCACGGCGGCGCTGCGCAAGCAGGGCCTCACGGTGGTCAAGCTCAAGAAGCGCAAGGCCGCGCGCGGCAAG
AAGATCACCGAGAAGGACATCGCGTATTTCACGCGCCAGCTTTCGACCATGCTGAAGGCCGGCATTCCGCTGCTGCAGTC
GATCGACATCATCGCGCGCGGGCACGCCAATCCGAACTTCACGCAGCTGCTGTCCGACATCCGCTTCGACATCGAATCCG
GCAGCAGCATGGCGGCGGCGTTCCGACGCCATCCGCGCTACTTCGACACGCTGTACTGCAACCTGATCGACGCCGGCGAG
CAGGGCGGTATTCTCGACTCCCTGCTCGAGCGCCTGTCGCTCTACATGGAAAAGACCATCGCGCTGAAGAGCCAGATCAA
GTCCGCGATGATCTACCCGATCGCGGTGCTGACCGTGGCCTTTGCCGTGACGGTGATCCTGATGCTGTTCGTGATCCCGG
CGTTCAAGGGCGTGTTCTCGAGCTTCGGCGCGAACCTGCCGGCGCCGACGCTGGTCGTGATCGCCATCTCGGACTTCTTC
GTCGCGTACTGGTACATCGTCATCGGCATACCGGTGGGGGCAATCGCGTTCTATTTACGGGCCTTGAAGAAATCCGAGAA
GGTCCAGCGCACCACGGACCGCATAATGCTGAAGCTGCCCATTTTCGGCAGCCTCTTCCGCAAGGCCGTGATCGCGCGCT
GGACGCGTACGCTCGCCACCATGTTCGCGGCGGGTACGCCGCTGGTGGAATCGATGGAATCCGTGGCCGGCGCGGCGGGC
AACTGGGTCTACTACGACGCCACGCGCGAGATCGAACAGTCCGTGCGCATCGGTACCAGCCTGACCAACGCCATGCAAGC
CACGCACGTGTTCGACAACATGGTGCTGCAGATGACGCAGATCGGCGAGGAATCGGGCGCGCTGGACAATATGCTCATCA
AGGTGGCGGAGTTCTACGAGCGCGAGGTCGATGACGCCGTGGCGGCCATTTCGAGCCTGATCGAGCCGCTCATCATCGTG
GTGCTGGGCGTGCTCATCGGCGGTATGGTGGTGGCAATGTACCTGCCGATCTTCAAGCTGGGACAGGTGGTGTAA

Upstream 100 bases:

>100_bases
GCCTGCTCAAGGTCAAGCAAGGGGTCACGTCACTCGAAGAAGTGCTGGCCACCACCAATTCATAAAACTACAGACAAAAC
ATTCATGTCGGGGGTCGATC

Downstream 100 bases:

>100_bases
TTGATGAATCCGGCATTCCCCGCCGGCGGCGCCTTTGCGCTGCCGGCGCTGGCGGCACTGCCGCCGTCGTTCCTGGTGGC
GGCAGCCGCCGTGCTCGGCC

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MATRAPAASARAAVPPRAKAGRAGRKAPTQYIFEWEGKDRKGKTFTGEQRAENQAEVTAALRKQGLTVVKLKKRKAARGK
KITEKDIAYFTRQLSTMLKAGIPLLQSIDIIARGHANPNFTQLLSDIRFDIESGSSMAAAFRRHPRYFDTLYCNLIDAGE
QGGILDSLLERLSLYMEKTIALKSQIKSAMIYPIAVLTVAFAVTVILMLFVIPAFKGVFSSFGANLPAPTLVVIAISDFF
VAYWYIVIGIPVGAIAFYLRALKKSEKVQRTTDRIMLKLPIFGSLFRKAVIARWTRTLATMFAAGTPLVESMESVAGAAG
NWVYYDATREIEQSVRIGTSLTNAMQATHVFDNMVLQMTQIGEESGALDNMLIKVAEFYEREVDDAVAAISSLIEPLIIV
VLGVLIGGMVVAMYLPIFKLGQVV

Sequences:

>Translated_424_residues
MATRAPAASARAAVPPRAKAGRAGRKAPTQYIFEWEGKDRKGKTFTGEQRAENQAEVTAALRKQGLTVVKLKKRKAARGK
KITEKDIAYFTRQLSTMLKAGIPLLQSIDIIARGHANPNFTQLLSDIRFDIESGSSMAAAFRRHPRYFDTLYCNLIDAGE
QGGILDSLLERLSLYMEKTIALKSQIKSAMIYPIAVLTVAFAVTVILMLFVIPAFKGVFSSFGANLPAPTLVVIAISDFF
VAYWYIVIGIPVGAIAFYLRALKKSEKVQRTTDRIMLKLPIFGSLFRKAVIARWTRTLATMFAAGTPLVESMESVAGAAG
NWVYYDATREIEQSVRIGTSLTNAMQATHVFDNMVLQMTQIGEESGALDNMLIKVAEFYEREVDDAVAAISSLIEPLIIV
VLGVLIGGMVVAMYLPIFKLGQVV
>Mature_423_residues
ATRAPAASARAAVPPRAKAGRAGRKAPTQYIFEWEGKDRKGKTFTGEQRAENQAEVTAALRKQGLTVVKLKKRKAARGKK
ITEKDIAYFTRQLSTMLKAGIPLLQSIDIIARGHANPNFTQLLSDIRFDIESGSSMAAAFRRHPRYFDTLYCNLIDAGEQ
GGILDSLLERLSLYMEKTIALKSQIKSAMIYPIAVLTVAFAVTVILMLFVIPAFKGVFSSFGANLPAPTLVVIAISDFFV
AYWYIVIGIPVGAIAFYLRALKKSEKVQRTTDRIMLKLPIFGSLFRKAVIARWTRTLATMFAAGTPLVESMESVAGAAGN
WVYYDATREIEQSVRIGTSLTNAMQATHVFDNMVLQMTQIGEESGALDNMLIKVAEFYEREVDDAVAAISSLIEPLIIVV
LGVLIGGMVVAMYLPIFKLGQVV

Specific function: Involved in the translocation of the type IV pilin [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=403, Percent_Identity=26.7990074441687, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1786295, Length=394, Percent_Identity=29.6954314720812, Blast_Score=162, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 46560; Mature: 46429

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRAPAASARAAVPPRAKAGRAGRKAPTQYIFEWEGKDRKGKTFTGEQRAENQAEVTAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHCCHHHHHHHH
LRKQGLTVVKLKKRKAARGKKITEKDIAYFTRQLSTMLKAGIPLLQSIDIIARGHANPNF
HHHCCCCEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCH
TQLLSDIRFDIESGSSMAAAFRRHPRYFDTLYCNLIDAGEQGGILDSLLERLSLYMEKTI
HHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
ALKSQIKSAMIYPIAVLTVAFAVTVILMLFVIPAFKGVFSSFGANLPAPTLVVIAISDFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHH
VAYWYIVIGIPVGAIAFYLRALKKSEKVQRTTDRIMLKLPIFGSLFRKAVIARWTRTLAT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHH
MFAAGTPLVESMESVAGAAGNWVYYDATREIEQSVRIGTSLTNAMQATHVFDNMVLQMTQ
HHHCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGEESGALDNMLIKVAEFYEREVDDAVAAISSLIEPLIIVVLGVLIGGMVVAMYLPIFKL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQVV
HCCC
>Mature Secondary Structure 
ATRAPAASARAAVPPRAKAGRAGRKAPTQYIFEWEGKDRKGKTFTGEQRAENQAEVTAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHCCHHHHHHHH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HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8820654 [H]