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The map label for this gene is ubiA [H]

Identifier: 73542488

GI number: 73542488

Start: 3072047

End: 3072904

Strand: Reverse

Name: ubiA [H]

Synonym: Reut_A2803

Alternate gene names: 73542488

Gene position: 3072904-3072047 (Counterclockwise)

Preceding gene: 73542489

Following gene: 73542485

Centisome position: 80.73

GC content: 63.4

Gene sequence:

>858_bases
ATGTCTGAACGCCTAGCCCTCTATGCGCGCCTGGTGCGCATCGACAAGCCCATCGGCACGCTGCTGCTGCTGTGGCCCAC
GCTGTGGGCGCTGTGGATGGCGGCCGGTGGCCCACCTGCGCTGAGCGTGTTCTGCATCTTCTTTGCCGGCACGTTCCTGA
TGCGCTCGGCAGGCTGCGCGATCAACGACTATGCCGACCGCGATTTTGACAAGCATGTGAAACGCACGAAGGAACGCCCG
CTGACCGCGGGAAAGATCGCGGCGTGGGAAGCGGTGCTGATTGCCGCCGTGCTCGCGCTGATCGCATTCGCGCTGATCCT
GCCGCTGAACAGCCTGACCAAATGGCTCGCGGTGGTGGCTGCCGTGGTAGCTGGCACGTATCCGTTCTTCAAGCGCTTTT
TCGCGATTCCGCAGGCTTACCTCGGCATTGCGTTTGGCTTCGGCATTCCGATGGCATTCGCGGCCGTGCAGGATCAGGTG
CCGCTGGTGGCGTGGGTGATGTTGCTGGCGAATGTGTTCTGGGCGGTCGCCTATGACACGGCCTACGCGATGGTGGACCG
CGACGATGACCTGCTGATTGGCATCAAGACTTCGGCCATCACGTTTGGCCGCTTTGATGTGGCCGCGATCATGCTGTGCT
ACGCGGCGTTCCTGGTGCTGATGGGCTGGGCAGGCGTGATGCTGTCGCTGGGGTGGCCGTATTGGGTGGGGCTGGCTGCT
GCGGCGGTTTGCGCCGGCTATCACTACACGCTGATCCGCGACCGGGATCGCATGCGGTGTTTTGCGGCGTTTCGCCATAA
CAACTGGCTGGGTGCCTGCGTGTTTGCGGGAACCGCGGTGGCCTACGCGATCCGCTAG

Upstream 100 bases:

>100_bases
CGGCGCGTTTTCGTTCGATGGGCGCTGTCCGTTGAACGCGTGCTCCTCCGATTCCTCTCGCCCCGCTGTCGCCGTGTTGC
TTTCCTTCCCCCAAGCTCCC

Downstream 100 bases:

>100_bases
GTTTTCTCCCCTCTCCCCTTCACAAGGGAGGGGGGAGCCGGTCTGCTGTATGGCGAGCGCCCTGTCAGATTAAACGCCCG
CTCAATCCTTCCCGAACTCT

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSERLALYARLVRIDKPIGTLLLLWPTLWALWMAAGGPPALSVFCIFFAGTFLMRSAGCAINDYADRDFDKHVKRTKERP
LTAGKIAAWEAVLIAAVLALIAFALILPLNSLTKWLAVVAAVVAGTYPFFKRFFAIPQAYLGIAFGFGIPMAFAAVQDQV
PLVAWVMLLANVFWAVAYDTAYAMVDRDDDLLIGIKTSAITFGRFDVAAIMLCYAAFLVLMGWAGVMLSLGWPYWVGLAA
AAVCAGYHYTLIRDRDRMRCFAAFRHNNWLGACVFAGTAVAYAIR

Sequences:

>Translated_285_residues
MSERLALYARLVRIDKPIGTLLLLWPTLWALWMAAGGPPALSVFCIFFAGTFLMRSAGCAINDYADRDFDKHVKRTKERP
LTAGKIAAWEAVLIAAVLALIAFALILPLNSLTKWLAVVAAVVAGTYPFFKRFFAIPQAYLGIAFGFGIPMAFAAVQDQV
PLVAWVMLLANVFWAVAYDTAYAMVDRDDDLLIGIKTSAITFGRFDVAAIMLCYAAFLVLMGWAGVMLSLGWPYWVGLAA
AAVCAGYHYTLIRDRDRMRCFAAFRHNNWLGACVFAGTAVAYAIR
>Mature_284_residues
SERLALYARLVRIDKPIGTLLLLWPTLWALWMAAGGPPALSVFCIFFAGTFLMRSAGCAINDYADRDFDKHVKRTKERPL
TAGKIAAWEAVLIAAVLALIAFALILPLNSLTKWLAVVAAVVAGTYPFFKRFFAIPQAYLGIAFGFGIPMAFAAVQDQVP
LVAWVMLLANVFWAVAYDTAYAMVDRDDDLLIGIKTSAITFGRFDVAAIMLCYAAFLVLMGWAGVMLSLGWPYWVGLAAA
AVCAGYHYTLIRDRDRMRCFAAFRHNNWLGACVFAGTAVAYAIR

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=277, Percent_Identity=35.3790613718412, Blast_Score=148, Evalue=7e-36,
Organism=Escherichia coli, GI1790473, Length=281, Percent_Identity=51.6014234875445, Blast_Score=281, Evalue=3e-77,
Organism=Escherichia coli, GI1786631, Length=186, Percent_Identity=25.2688172043011, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17553718, Length=294, Percent_Identity=37.0748299319728, Blast_Score=161, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI32565247, Length=282, Percent_Identity=35.8156028368794, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17553720, Length=339, Percent_Identity=31.5634218289086, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32565245, Length=146, Percent_Identity=46.5753424657534, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32565243, Length=142, Percent_Identity=46.4788732394366, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324370, Length=287, Percent_Identity=31.0104529616725, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21355567, Length=283, Percent_Identity=34.982332155477, Blast_Score=151, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 31331; Mature: 31200

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLALYARLVRIDKPIGTLLLLWPTLWALWMAAGGPPALSVFCIFFAGTFLMRSAGCA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
INDYADRDFDKHVKRTKERPLTAGKIAAWEAVLIAAVLALIAFALILPLNSLTKWLAVVA
CCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVAGTYPFFKRFFAIPQAYLGIAFGFGIPMAFAAVQDQVPLVAWVMLLANVFWAVAYDT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AYAMVDRDDDLLIGIKTSAITFGRFDVAAIMLCYAAFLVLMGWAGVMLSLGWPYWVGLAA
HHHEEECCCCEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAVCAGYHYTLIRDRDRMRCFAAFRHNNWLGACVFAGTAVAYAIR
HHHHHCCHHEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SERLALYARLVRIDKPIGTLLLLWPTLWALWMAAGGPPALSVFCIFFAGTFLMRSAGCA
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
INDYADRDFDKHVKRTKERPLTAGKIAAWEAVLIAAVLALIAFALILPLNSLTKWLAVVA
CCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVAGTYPFFKRFFAIPQAYLGIAFGFGIPMAFAAVQDQVPLVAWVMLLANVFWAVAYDT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AYAMVDRDDDLLIGIKTSAITFGRFDVAAIMLCYAAFLVLMGWAGVMLSLGWPYWVGLAA
HHHEEECCCCEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAVCAGYHYTLIRDRDRMRCFAAFRHNNWLGACVFAGTAVAYAIR
HHHHHCCHHEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA