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The map label for this gene is rsmB [H]

Identifier: 73542425

GI number: 73542425

Start: 3007431

End: 3008708

Strand: Reverse

Name: rsmB [H]

Synonym: Reut_A2740

Alternate gene names: 73542425

Gene position: 3008708-3007431 (Counterclockwise)

Preceding gene: 73542426

Following gene: 73542424

Centisome position: 79.04

GC content: 65.57

Gene sequence:

>1278_bases
GTGCACGGAGGCCTGCACGCGTCCCATATCCAGCATATCGACCGGCTGCTCGGCAAGGTCATGCTGTTTGCGCGTCCGGC
CGACGCCGTGGTGAGCTATTACTTCCGCGAGAACAGCAAGCTTGGCCATCGCGAGCGCGGCATCATTGCCGAGGCGGTCT
ACGCGGTGCTGCGCCGGCGCGTGGAGTTCGGTCAGTTTGCCGAAAGCGGCACCGGTTCGGCCTCGCGCCGCCTGGCGCTG
CTGGGCCTGGCGGCAACACTGGGCCGCGATACGCTTACGCCGTTCCTCTATCCCGACGAGGCCGAGTGGCTGGACCGCCT
GACCACGATCGAGCGATCGAGCCTGTCGCCGCGTGTACGGGCGAACCTGCCCGAGTGGCTGTTCGATAACCTCGTGGCGC
GCCATGGCGAAGCCTTTACGTCGGCGCTCGGCGACGCCTGGTTGCGCCCGGCGCCGTTGGATCTGCGTGTAAATCTCATC
AAGACCACGCGCGAGGCAGCACTCGCCGAGCTCGAGGCGGCAGGTTTGCGTGCCGAGCCCACGCCGATGGCTCCCGCCGG
CATCCGCATGCAAGGCAAGCCTGCGCTGAACCAGTTGCCGATGTTCGTGAACGGCCTGGTGGAAGTCCAGGATGAGGGTA
GCCAGCTGCTGTGCAGCCTGGTAGGACCGAAGCGCGGCGAGATGGTCGTCGATTTCTGTGCCGGCGCAGGCGGCAAGACC
TTGGCGCTTGGCGTGGCCATGCGCTCGACTGGCCGACTCTATGCCTTCGATGTGTCGGAAAAGCGGCTTGCCAACCTGAA
GCCGCGGCTTGCGCGCAGCGGTTTGTCGAACGTGCACCCGGTGCTGATCGACTCGGAGCGCGATGCCAAGGTCAAGCGCC
TGGCGGGCAAGATCGACCGCGTGCTGGTAGACGCGCCGTGCAGCGGGCTCGGGACGCTGCGGCGCAATCCCGACCTGAAG
TGGCGCCAGAACCCCGAATCGGTGCTTGAGCTGACCGCCAAGCAGAGCGCGATCCTCGAGGCTGCGGCACGGCTCGTCAA
AGGTGGGGGGCGAGTGGTGTATGCCACTTGCAGTGTGCTTGAGGCGGAGAATGAGGCGATCGTTCGAGACTTCCTCGCCA
AACACCCGACTTTCCGGCTGGTCCCGGCGACGGAAGTGCTGGCCGAGCAAAAGATCGAAGTGCCAGCGTTGCAGACAGAA
GGCGACATGTTCGCGCTGTATCCCCATCTGCATCAGACCGACGGCTTCTTCGCCGCCGTGCTGGAGCGTACGCAGTAA

Upstream 100 bases:

>100_bases
TTCCCGCCAACCTGCTAAAGCCCGCAAGTCGAGCCCGATCCGCAGGCCGGCAAACGCGCGGTCCGCTCAGGGTCCGGGAG
CGGATGGTCAGCCCACGCGC

Downstream 100 bases:

>100_bases
TCTCCCCATCCCACCGGCACTCGCGCGGTTCGCGCGGCTGCCGGTGCGGCGACAGGGTATCCAGGCAGAATTCCCATGAA
CGGAAACCCATTAACGGACC

Product: Fmu

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MHGGLHASHIQHIDRLLGKVMLFARPADAVVSYYFRENSKLGHRERGIIAEAVYAVLRRRVEFGQFAESGTGSASRRLAL
LGLAATLGRDTLTPFLYPDEAEWLDRLTTIERSSLSPRVRANLPEWLFDNLVARHGEAFTSALGDAWLRPAPLDLRVNLI
KTTREAALAELEAAGLRAEPTPMAPAGIRMQGKPALNQLPMFVNGLVEVQDEGSQLLCSLVGPKRGEMVVDFCAGAGGKT
LALGVAMRSTGRLYAFDVSEKRLANLKPRLARSGLSNVHPVLIDSERDAKVKRLAGKIDRVLVDAPCSGLGTLRRNPDLK
WRQNPESVLELTAKQSAILEAAARLVKGGGRVVYATCSVLEAENEAIVRDFLAKHPTFRLVPATEVLAEQKIEVPALQTE
GDMFALYPHLHQTDGFFAAVLERTQ

Sequences:

>Translated_425_residues
MHGGLHASHIQHIDRLLGKVMLFARPADAVVSYYFRENSKLGHRERGIIAEAVYAVLRRRVEFGQFAESGTGSASRRLAL
LGLAATLGRDTLTPFLYPDEAEWLDRLTTIERSSLSPRVRANLPEWLFDNLVARHGEAFTSALGDAWLRPAPLDLRVNLI
KTTREAALAELEAAGLRAEPTPMAPAGIRMQGKPALNQLPMFVNGLVEVQDEGSQLLCSLVGPKRGEMVVDFCAGAGGKT
LALGVAMRSTGRLYAFDVSEKRLANLKPRLARSGLSNVHPVLIDSERDAKVKRLAGKIDRVLVDAPCSGLGTLRRNPDLK
WRQNPESVLELTAKQSAILEAAARLVKGGGRVVYATCSVLEAENEAIVRDFLAKHPTFRLVPATEVLAEQKIEVPALQTE
GDMFALYPHLHQTDGFFAAVLERTQ
>Mature_425_residues
MHGGLHASHIQHIDRLLGKVMLFARPADAVVSYYFRENSKLGHRERGIIAEAVYAVLRRRVEFGQFAESGTGSASRRLAL
LGLAATLGRDTLTPFLYPDEAEWLDRLTTIERSSLSPRVRANLPEWLFDNLVARHGEAFTSALGDAWLRPAPLDLRVNLI
KTTREAALAELEAAGLRAEPTPMAPAGIRMQGKPALNQLPMFVNGLVEVQDEGSQLLCSLVGPKRGEMVVDFCAGAGGKT
LALGVAMRSTGRLYAFDVSEKRLANLKPRLARSGLSNVHPVLIDSERDAKVKRLAGKIDRVLVDAPCSGLGTLRRNPDLK
WRQNPESVLELTAKQSAILEAAARLVKGGGRVVYATCSVLEAENEAIVRDFLAKHPTFRLVPATEVLAEQKIEVPALQTE
GDMFALYPHLHQTDGFFAAVLERTQ

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=287, Percent_Identity=29.616724738676, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI76150623, Length=287, Percent_Identity=29.616724738676, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI8922322, Length=252, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI23199998, Length=252, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI270288816, Length=252, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI270288818, Length=252, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI32698918, Length=228, Percent_Identity=28.5087719298246, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI39995082, Length=275, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI301336155, Length=207, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367212, Length=308, Percent_Identity=32.4675324675325, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI87081985, Length=289, Percent_Identity=28.719723183391, Blast_Score=108, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=289, Percent_Identity=28.719723183391, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71998419, Length=295, Percent_Identity=27.7966101694915, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25143471, Length=236, Percent_Identity=32.2033898305085, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115534021, Length=220, Percent_Identity=30.9090909090909, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=286, Percent_Identity=27.6223776223776, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6319447, Length=245, Percent_Identity=31.0204081632653, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI22024126, Length=285, Percent_Identity=28.7719298245614, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21355201, Length=256, Percent_Identity=31.25, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356579, Length=218, Percent_Identity=26.605504587156, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24668781, Length=220, Percent_Identity=32.2727272727273, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356513, Length=220, Percent_Identity=32.2727272727273, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46516; Mature: 46516

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGGLHASHIQHIDRLLGKVMLFARPADAVVSYYFRENSKLGHRERGIIAEAVYAVLRRR
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHH
VEFGQFAESGTGSASRRLALLGLAATLGRDTLTPFLYPDEAEWLDRLTTIERSSLSPRVR
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHH
ANLPEWLFDNLVARHGEAFTSALGDAWLRPAPLDLRVNLIKTTREAALAELEAAGLRAEP
CCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCC
TPMAPAGIRMQGKPALNQLPMFVNGLVEVQDEGSQLLCSLVGPKRGEMVVDFCAGAGGKT
CCCCCCCCEECCCCCHHHCCHHHHHHEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCE
LALGVAMRSTGRLYAFDVSEKRLANLKPRLARSGLSNVHPVLIDSERDAKVKRLAGKIDR
EEEEEEECCCCCEEEEECCHHHHHCCCHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHH
VLVDAPCSGLGTLRRNPDLKWRQNPESVLELTAKQSAILEAAARLVKGGGRVVYATCSVL
EEEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHH
EAENEAIVRDFLAKHPTFRLVPATEVLAEQKIEVPALQTEGDMFALYPHLHQTDGFFAAV
HCCCHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCEECCCCEEEECCCCCCCCCHHHHH
LERTQ
HHHCC
>Mature Secondary Structure
MHGGLHASHIQHIDRLLGKVMLFARPADAVVSYYFRENSKLGHRERGIIAEAVYAVLRRR
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHH
VEFGQFAESGTGSASRRLALLGLAATLGRDTLTPFLYPDEAEWLDRLTTIERSSLSPRVR
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHH
ANLPEWLFDNLVARHGEAFTSALGDAWLRPAPLDLRVNLIKTTREAALAELEAAGLRAEP
CCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCC
TPMAPAGIRMQGKPALNQLPMFVNGLVEVQDEGSQLLCSLVGPKRGEMVVDFCAGAGGKT
CCCCCCCCEECCCCCHHHCCHHHHHHEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCE
LALGVAMRSTGRLYAFDVSEKRLANLKPRLARSGLSNVHPVLIDSERDAKVKRLAGKIDR
EEEEEEECCCCCEEEEECCHHHHHCCCHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHH
VLVDAPCSGLGTLRRNPDLKWRQNPESVLELTAKQSAILEAAARLVKGGGRVVYATCSVL
EEEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHH
EAENEAIVRDFLAKHPTFRLVPATEVLAEQKIEVPALQTEGDMFALYPHLHQTDGFFAAV
HCCCHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCEECCCCEEEECCCCCCCCCHHHHH
LERTQ
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]