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The map label for this gene is yjeP [H]

Identifier: 73542424

GI number: 73542424

Start: 3005982

End: 3007355

Strand: Reverse

Name: yjeP [H]

Synonym: Reut_A2739

Alternate gene names: 73542424

Gene position: 3007355-3005982 (Counterclockwise)

Preceding gene: 73542425

Following gene: 73542423

Centisome position: 79.01

GC content: 61.35

Gene sequence:

>1374_bases
ATGAACGGAAACCCATTAACGGACCTGACGGCTTCGCACGCGACGTTCGGCAGAATGCTCGACGACTTGATGCGGGACGC
AGGCGGGCCCGGCTTCATCTGGCAACTTGTCGTGCTGGCCGGCTGCCTGCTGGCCGCCTGGCCGCTCGCGCGTTTTGTCG
ACAAGCGGCTCGAGAAACACTACGCCGCCTCCAGCTTCTCGCTGCGCTTCGCCGCGGCCAGCCTTGAGCGGGCGATGTTC
CCGCTGTTCGGCTGGCTGCTGGTCATGACGGCCCGCTTCGTGCTGGAGCCTGTCATGGCGATCAGCGTGCTGCGGCTCGC
GCTCGTGCCGTTATTTGGCATCACGTCGCTGTACTTCACCTTCTACATCCTGCGCCGGGTGCTCTCGGGCAGCGGCCAGT
TGCACGGCATGCTGCTCCTTGTCGAGAAGGTGCTGACTACGCTGGTGTGGGTGGCCATGGCGCTGTATGTGCTGGGGGTG
TTGCCGGAGGTGACCAAGTGGATGGAGGCCATGCGCTTCTCGCTCGGCAAGCAGAAGGTGAGCCTTGCAGACATTCTGAT
GGCCGTGGTGTGGATCCTGCTGACCGTGCTGGTCGCGATGTGGTTCGGATCTTGGCTGGAAGAGCGCCTGATGCGCTCGG
CCAGCCTCGACGTGAACCTGAAGGTGGTGCTGACACGCATTTCCAAGGCGCTGCTGCTGCTGGTGTCACTGCTGCTGAGC
CTGTCCCTGGTCGGTATCGACCTGACGGTGTTGTCGGTGTTTGGCGGCGCGCTGGGTGTTGGCCTTGGTCTTGGCTTGCA
GAAAATCGCCAGTAACTATATTTCGGGCTTCATCATCCTGCTCGATCGTTCCGTGAAACTTGGCGATCAGATCACGGTGG
ACAAGTGCACGGGCATCGTCTCGCAGATCCGCACCCGCTACACGGTCGTCCGCAATGGCGATGGCGAGACGCTGGTGCCG
AACGAGCAGCTGGTGGCCCAATCAGTGCAAAACCACTCGTTTTCGAACACCAATGTCCGCGTGGCAACACGCGTGCAGGC
TGATTACGGCGCCGATCCTGAGACTGTGATCATGCTGCTGACGGAATGTGTCCGCGAACTGCCTCGAGTGCTGCAGGATC
CGGCACCGGCGGCGTTCTTGGTTCTGTTTGCTGACAGCGGCATCGAATATGAAGTCGCGGTTTATATCGCCGATCCGCAG
AACGGCAAGCTTGGCGTGCAATCCGCCATGAACCGCGCGATCTGGCGGACGCTGCGCGAGCACGGCATCTCCATTCCTTA
TCCCCAGCGCGAGGTCCGTGTGTTGACCAATGGTCACTTTCAGTCGTTGAGTGACGCCTCCGCGCAAGCCGTAGAAGTGG
CGAATCAGGCATGA

Upstream 100 bases:

>100_bases
CGCCGTGCTGGAGCGTACGCAGTAATCTCCCCATCCCACCGGCACTCGCGCGGTTCGCGCGGCTGCCGGTGCGGCGACAG
GGTATCCAGGCAGAATTCCC

Downstream 100 bases:

>100_bases
CTGTATAAGGAAACAGGCGGGCGCTTCACAAGGGAACAAAAATGAAGCGTGCCCGTCAAACTCGGGGAAAAAGCGTATGA
CTCAGACCTGCATGATCCGG

Product: MscS mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MNGNPLTDLTASHATFGRMLDDLMRDAGGPGFIWQLVVLAGCLLAAWPLARFVDKRLEKHYAASSFSLRFAAASLERAMF
PLFGWLLVMTARFVLEPVMAISVLRLALVPLFGITSLYFTFYILRRVLSGSGQLHGMLLLVEKVLTTLVWVAMALYVLGV
LPEVTKWMEAMRFSLGKQKVSLADILMAVVWILLTVLVAMWFGSWLEERLMRSASLDVNLKVVLTRISKALLLLVSLLLS
LSLVGIDLTVLSVFGGALGVGLGLGLQKIASNYISGFIILLDRSVKLGDQITVDKCTGIVSQIRTRYTVVRNGDGETLVP
NEQLVAQSVQNHSFSNTNVRVATRVQADYGADPETVIMLLTECVRELPRVLQDPAPAAFLVLFADSGIEYEVAVYIADPQ
NGKLGVQSAMNRAIWRTLREHGISIPYPQREVRVLTNGHFQSLSDASAQAVEVANQA

Sequences:

>Translated_457_residues
MNGNPLTDLTASHATFGRMLDDLMRDAGGPGFIWQLVVLAGCLLAAWPLARFVDKRLEKHYAASSFSLRFAAASLERAMF
PLFGWLLVMTARFVLEPVMAISVLRLALVPLFGITSLYFTFYILRRVLSGSGQLHGMLLLVEKVLTTLVWVAMALYVLGV
LPEVTKWMEAMRFSLGKQKVSLADILMAVVWILLTVLVAMWFGSWLEERLMRSASLDVNLKVVLTRISKALLLLVSLLLS
LSLVGIDLTVLSVFGGALGVGLGLGLQKIASNYISGFIILLDRSVKLGDQITVDKCTGIVSQIRTRYTVVRNGDGETLVP
NEQLVAQSVQNHSFSNTNVRVATRVQADYGADPETVIMLLTECVRELPRVLQDPAPAAFLVLFADSGIEYEVAVYIADPQ
NGKLGVQSAMNRAIWRTLREHGISIPYPQREVRVLTNGHFQSLSDASAQAVEVANQA
>Mature_457_residues
MNGNPLTDLTASHATFGRMLDDLMRDAGGPGFIWQLVVLAGCLLAAWPLARFVDKRLEKHYAASSFSLRFAAASLERAMF
PLFGWLLVMTARFVLEPVMAISVLRLALVPLFGITSLYFTFYILRRVLSGSGQLHGMLLLVEKVLTTLVWVAMALYVLGV
LPEVTKWMEAMRFSLGKQKVSLADILMAVVWILLTVLVAMWFGSWLEERLMRSASLDVNLKVVLTRISKALLLLVSLLLS
LSLVGIDLTVLSVFGGALGVGLGLGLQKIASNYISGFIILLDRSVKLGDQITVDKCTGIVSQIRTRYTVVRNGDGETLVP
NEQLVAQSVQNHSFSNTNVRVATRVQADYGADPETVIMLLTECVRELPRVLQDPAPAAFLVLFADSGIEYEVAVYIADPQ
NGKLGVQSAMNRAIWRTLREHGISIPYPQREVRVLTNGHFQSLSDASAQAVEVANQA

Specific function: Unknown

COG id: COG3264

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI2367355, Length=259, Percent_Identity=31.2741312741313, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786670, Length=212, Percent_Identity=33.4905660377358, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789291, Length=255, Percent_Identity=27.4509803921569, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787591, Length=254, Percent_Identity=25.1968503937008, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 50179; Mature: 50179

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCHHHEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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CCCCCCCCCHHHEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 3042771 [H]