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The map label for this gene is 73542240

Identifier: 73542240

GI number: 73542240

Start: 2799370

End: 2800293

Strand: Reverse

Name: 73542240

Synonym: Reut_A2555

Alternate gene names: NA

Gene position: 2800293-2799370 (Counterclockwise)

Preceding gene: 73542245

Following gene: 73542239

Centisome position: 73.57

GC content: 66.45

Gene sequence:

>924_bases
ATGCCGACGGGCTATTACACGCATCCGGAGTTCCTTTTGCACGAGATGGGCCATTTCCATCCCGAGTGCCCGGAACGCCT
GCAGGCGATCGAGGATCACCTGATTTCCCACGGCATGGACGGCCTGCTGGAGCGCCGTGAAGCGGCGCCCGCGACCCGCG
AGCAGATCGAACGCGTACACGGGGCCGCTTATGTCGATTCGCTGGAGCGCGCGAGCCCCGCCAGCGGCTACTACCCGATC
GATCCCGACACATCGATGAATTCGCACACGCTGGCAGCCGCGAAGCTGGCAGCGGGGGCGGCCGTGGCGGCTACCGATGC
CGTCATGGCGGGCGAGGTGGAAAACGCGTTCTGCTGCGTGCGTCCGCCCGGACACCATGCCGAGCCCGACCGCGCCATGG
GCTTCTGCTTCTTCAACAACGTGGCCGTCGCGGCCCGCCATGCGCTGGCAGCGCACGGGCTGGAGCGCGTGGCCGTCGTC
GACTTCGACGTCCATCACGGCAACGGCACCGAGGCAGCGTTCCGGGGCGACGATCGCGTGCTGATGTGCAGCTTCTTCCA
GCACCCGTTCTATCCCTACAGCGGCACCGAGCATATCGCCACGAACATGGCGAATATCCCGCTGCCTGCCTATACCAACG
GGCTCGCGGTGCGCGAGGTGGTCGACACCATCTGGCTGCCGCGGCTGAACGAGTTCCGCCCGCAGATGCTGTTCATCTCG
GCCGGCTTTGACGCCCACCGCGAGGACGACCTGGGTCAGATGGGCCTGGTCGAGCAGGACTATGCGTGGATCACGGGGCA
GCTCGTCGATGTGGCCCGCGCGCATGCGAACGGCCGCATCGTCAGCTGTCTCGAGGGCGGCTACAACCTCAGCGCGCTGG
GCCGCAGCGTGCTGGCACACCTGAAAGTGCTGCTGGAACGATAA

Upstream 100 bases:

>100_bases
AATTGCCGCGGATATGGCGCCGCCACGGGCCCTGGCGGTCCGCTGGGGGGCTTGTCCTGTGCTAACGTAACGTTTGGAGA
CAAAACAACGAAGATAAGAC

Downstream 100 bases:

>100_bases
GGAGCAAGCCCGCATGGCCGACACCGATCCGCGCACGAGCGCACCCCTGCTGACCGAGTCGCGCGATGCCGCGGGCGTGG
CGCGCCTGACCATGAACCGC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MPTGYYTHPEFLLHEMGHFHPECPERLQAIEDHLISHGMDGLLERREAAPATREQIERVHGAAYVDSLERASPASGYYPI
DPDTSMNSHTLAAAKLAAGAAVAATDAVMAGEVENAFCCVRPPGHHAEPDRAMGFCFFNNVAVAARHALAAHGLERVAVV
DFDVHHGNGTEAAFRGDDRVLMCSFFQHPFYPYSGTEHIATNMANIPLPAYTNGLAVREVVDTIWLPRLNEFRPQMLFIS
AGFDAHREDDLGQMGLVEQDYAWITGQLVDVARAHANGRIVSCLEGGYNLSALGRSVLAHLKVLLER

Sequences:

>Translated_307_residues
MPTGYYTHPEFLLHEMGHFHPECPERLQAIEDHLISHGMDGLLERREAAPATREQIERVHGAAYVDSLERASPASGYYPI
DPDTSMNSHTLAAAKLAAGAAVAATDAVMAGEVENAFCCVRPPGHHAEPDRAMGFCFFNNVAVAARHALAAHGLERVAVV
DFDVHHGNGTEAAFRGDDRVLMCSFFQHPFYPYSGTEHIATNMANIPLPAYTNGLAVREVVDTIWLPRLNEFRPQMLFIS
AGFDAHREDDLGQMGLVEQDYAWITGQLVDVARAHANGRIVSCLEGGYNLSALGRSVLAHLKVLLER
>Mature_306_residues
PTGYYTHPEFLLHEMGHFHPECPERLQAIEDHLISHGMDGLLERREAAPATREQIERVHGAAYVDSLERASPASGYYPID
PDTSMNSHTLAAAKLAAGAAVAATDAVMAGEVENAFCCVRPPGHHAEPDRAMGFCFFNNVAVAARHALAAHGLERVAVVD
FDVHHGNGTEAAFRGDDRVLMCSFFQHPFYPYSGTEHIATNMANIPLPAYTNGLAVREVVDTIWLPRLNEFRPQMLFISA
GFDAHREDDLGQMGLVEQDYAWITGQLVDVARAHANGRIVSCLEGGYNLSALGRSVLAHLKVLLER

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=301, Percent_Identity=38.2059800664452, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI20070354, Length=307, Percent_Identity=37.4592833876222, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI17158039, Length=325, Percent_Identity=33.8461538461538, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI30795204, Length=325, Percent_Identity=33.8461538461538, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI30795202, Length=325, Percent_Identity=33.8461538461538, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI153085395, Length=324, Percent_Identity=34.5679012345679, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI62750347, Length=331, Percent_Identity=33.2326283987915, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI62750349, Length=331, Percent_Identity=33.2326283987915, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI226529806, Length=304, Percent_Identity=34.8684210526316, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI148539870, Length=330, Percent_Identity=32.7272727272727, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI169234807, Length=318, Percent_Identity=33.0188679245283, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI13128860, Length=274, Percent_Identity=24.0875912408759, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI293336691, Length=274, Percent_Identity=24.0875912408759, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI13128862, Length=323, Percent_Identity=22.9102167182663, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193209491, Length=326, Percent_Identity=33.1288343558282, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17540334, Length=313, Percent_Identity=34.185303514377, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI193206283, Length=313, Percent_Identity=34.185303514377, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17540332, Length=313, Percent_Identity=34.185303514377, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25154020, Length=302, Percent_Identity=32.4503311258278, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25154022, Length=300, Percent_Identity=32, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17537347, Length=305, Percent_Identity=33.7704918032787, Blast_Score=137, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17534739, Length=272, Percent_Identity=26.8382352941176, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17508561, Length=319, Percent_Identity=25.0783699059561, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17561978, Length=268, Percent_Identity=25.7462686567164, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324307, Length=317, Percent_Identity=35.6466876971609, Blast_Score=161, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323999, Length=260, Percent_Identity=26.5384615384615, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321244, Length=260, Percent_Identity=26.9230769230769, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6325141, Length=285, Percent_Identity=27.0175438596491, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6325325, Length=176, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281360899, Length=306, Percent_Identity=35.9477124183007, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24642146, Length=306, Percent_Identity=35.9477124183007, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24642144, Length=306, Percent_Identity=35.9477124183007, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24642142, Length=306, Percent_Identity=35.9477124183007, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI281360799, Length=327, Percent_Identity=33.9449541284404, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281360801, Length=327, Percent_Identity=33.9449541284404, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24641720, Length=327, Percent_Identity=33.9449541284404, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24657891, Length=317, Percent_Identity=25.2365930599369, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644244, Length=319, Percent_Identity=23.1974921630094, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33651; Mature: 33520

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTGYYTHPEFLLHEMGHFHPECPERLQAIEDHLISHGMDGLLERREAAPATREQIERVH
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHH
GAAYVDSLERASPASGYYPIDPDTSMNSHTLAAAKLAAGAAVAATDAVMAGEVENAFCCV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEE
RPPGHHAEPDRAMGFCFFNNVAVAARHALAAHGLERVAVVDFDVHHGNGTEAAFRGDDRV
CCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCEECCCCCE
LMCSFFQHPFYPYSGTEHIATNMANIPLPAYTNGLAVREVVDTIWLPRLNEFRPQMLFIS
EEEEHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEE
AGFDAHREDDLGQMGLVEQDYAWITGQLVDVARAHANGRIVSCLEGGYNLSALGRSVLAH
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
LKVLLER
HHHHHCC
>Mature Secondary Structure 
PTGYYTHPEFLLHEMGHFHPECPERLQAIEDHLISHGMDGLLERREAAPATREQIERVH
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHH
GAAYVDSLERASPASGYYPIDPDTSMNSHTLAAAKLAAGAAVAATDAVMAGEVENAFCCV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEE
RPPGHHAEPDRAMGFCFFNNVAVAARHALAAHGLERVAVVDFDVHHGNGTEAAFRGDDRV
CCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCEECCCCCE
LMCSFFQHPFYPYSGTEHIATNMANIPLPAYTNGLAVREVVDTIWLPRLNEFRPQMLFIS
EEEEHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEE
AGFDAHREDDLGQMGLVEQDYAWITGQLVDVARAHANGRIVSCLEGGYNLSALGRSVLAH
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
LKVLLER
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]