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The map label for this gene is bcd [H]

Identifier: 73542233

GI number: 73542233

Start: 2792051

End: 2793835

Strand: Reverse

Name: bcd [H]

Synonym: Reut_A2548

Alternate gene names: 73542233

Gene position: 2793835-2792051 (Counterclockwise)

Preceding gene: 73542234

Following gene: 73542231

Centisome position: 73.4

GC content: 64.87

Gene sequence:

>1785_bases
ATGACCTACCGCGCACCGCTCAAGGACATGCTGTTCGTGATGAACGAGCTGGCCGGACTGGACGCCGTGAGCCAGTTGCC
TGGCTTTGAGGAAGCCACGCCGGAGACGGCGCAGGCCGTGCTGGAAGAGGCGGCCAAGTTCAATGAGCAGGTGGTGGCAC
CGCTGAACCGTGCGGGCGACCTGGACCCCAGCAGCTGGAAAGATGGCATGGTCACCACAACGCCTGGTTTCAAGGACGCA
TTCCGCCAGTTCGGCGAAGGCGGCTGGCAAGGCGTGCTGCATCCGCAGGAATTCGAGGGGCAGGGGCTGCCCAAGCTGAT
CGCCACGGCCTGCAACGAAATGCTCAACAGCGCGAATTTGTCGTTCGCGCTGTGCCCGTTGCTGACAGACGGCGCCATCG
AGGCCCTGCTGACCGCCGGCTCTGACGAGCAGAAGGCTACCTTCCTGCCAAAGCTGATTTGCGGCGAGTGGACCGGCACC
ATGAACTTGACCGAGCCGCAGGCCGGTTCGGACCTGGCCGCGGTGCGCACGCGTGCCGAACCGCAGGGCGACGGTACGTA
CAAGGTATTCGGCACCAAGATCTTCATCACCTATGGCGAGCACGACATGGCAGACAACATCGTCCACCTCGTGCTGGCGC
GTACGCCGAATGCGCCCGAAGGCGTGAAGGGCATCTCGCTGTTCATCGTGCCGAAGTTCCTGGTCAATGCAGACGGCTCG
CTCGGCGCGCGCAACGACGCGCATTGCGTGTCGATCGAGCACAAGCTGGGCATCAAGGCCAGCCCGACCGCAGTGCTGCA
GTTTGGCGACCACGGCGGTGCCATCGGTACGCTGGTGGGTGAAGAGAACCGCGGCCTCGAGTACATGTTCATCATGATGA
ACTCGGCGCGTTTCGCGGTCGGCATGCAGGGCATCGCGGTCTCCGAACGCGCTTACCAGCAGGCCGTGGCCTATGCGCGC
GAACGCGTGCAAAGCCGCCCGGTCGACGGCTCGGCGCGCGAGGCGGTGACGATCATCCATCATCCCGACGTCAAGCGGAT
GCTGATGACGATGCGCGGCCTGATCGAAGGCGCGCGCTCGGTGGCCTACGTGGCGGCCGCTACCTGCGATGCCGCGCACA
ACCATGCGGACGAAGCCGTGCGCACGAAGAACCAGGCGCTCTACGAGTTCCTGGTGCCAATCGTGAAAGGCTGGAGCACG
GAGCTTTCGATCGATGTGACGAGCCTGGGCGTGCAGGTGCATGGCGGCATGGGCTTCATCGAGGAAACCGGGGCGGCCCA
GCACTACCGCGACGCACGCATCCTACCGATCTACGAAGGCACGACGGCCATCCAGGCCAATGACCTCGTCGGCCGCAAGA
CGGTGCGTGATGGCGGTGCCGTCGCGCGTGCCTTCTGCGCCAGCATTGCCGAAACCGAAGCGGCGCTCGGCAAGCATGGC
GGTGCCGCGTTCACGGCCGTTCAGGCGCAACTGGCCAAGGGCCGTGCTGCGCTGGAAGCGGTTGTCGAGTTCGTGGTTGC
CAATGCCAAGTCAGACCCGAACGCAGTGTTCGCCGGCAGCGTGCCATACCTGAAGCTGTGCGGCATCGTGTTCTCGGGCT
GGCAGTTGGGCCGCGCGATGCTGGCGGCCGATGCAAAGCGCGCTGAAGATCCTGGCTTCCATGATGCCAAGATCGCGACG
GCGCACTTCTTTGCGGAGCACATCCTGTCGCAGGCGTCCGCGCTGCGCGATGCCATCGTCGCGGGTGCCGCGCCGGTGAA
TGCTGTCTCGCCCGATCAGTTCTGA

Upstream 100 bases:

>100_bases
ATCTATCGCCGGCCCTTGTGGCCGGCCCTGCAGAGATGCTGCATAAGCCGTTCCGGGCGTGTCCCGCGAACGGCTTTTTT
ATACACGATTGGAGACATCG

Downstream 100 bases:

>100_bases
TCCGGCGGTTCTCTGCAAATAAAAAGGGCGGCCCGTCGGGTCGCCCTTTTTGCTGGTGTGGCGCGCTGCGCCGAAGGTCA
AGCCGTAGCGGGACGCGGGG

Product: Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MTYRAPLKDMLFVMNELAGLDAVSQLPGFEEATPETAQAVLEEAAKFNEQVVAPLNRAGDLDPSSWKDGMVTTTPGFKDA
FRQFGEGGWQGVLHPQEFEGQGLPKLIATACNEMLNSANLSFALCPLLTDGAIEALLTAGSDEQKATFLPKLICGEWTGT
MNLTEPQAGSDLAAVRTRAEPQGDGTYKVFGTKIFITYGEHDMADNIVHLVLARTPNAPEGVKGISLFIVPKFLVNADGS
LGARNDAHCVSIEHKLGIKASPTAVLQFGDHGGAIGTLVGEENRGLEYMFIMMNSARFAVGMQGIAVSERAYQQAVAYAR
ERVQSRPVDGSAREAVTIIHHPDVKRMLMTMRGLIEGARSVAYVAAATCDAAHNHADEAVRTKNQALYEFLVPIVKGWST
ELSIDVTSLGVQVHGGMGFIEETGAAQHYRDARILPIYEGTTAIQANDLVGRKTVRDGGAVARAFCASIAETEAALGKHG
GAAFTAVQAQLAKGRAALEAVVEFVVANAKSDPNAVFAGSVPYLKLCGIVFSGWQLGRAMLAADAKRAEDPGFHDAKIAT
AHFFAEHILSQASALRDAIVAGAAPVNAVSPDQF

Sequences:

>Translated_594_residues
MTYRAPLKDMLFVMNELAGLDAVSQLPGFEEATPETAQAVLEEAAKFNEQVVAPLNRAGDLDPSSWKDGMVTTTPGFKDA
FRQFGEGGWQGVLHPQEFEGQGLPKLIATACNEMLNSANLSFALCPLLTDGAIEALLTAGSDEQKATFLPKLICGEWTGT
MNLTEPQAGSDLAAVRTRAEPQGDGTYKVFGTKIFITYGEHDMADNIVHLVLARTPNAPEGVKGISLFIVPKFLVNADGS
LGARNDAHCVSIEHKLGIKASPTAVLQFGDHGGAIGTLVGEENRGLEYMFIMMNSARFAVGMQGIAVSERAYQQAVAYAR
ERVQSRPVDGSAREAVTIIHHPDVKRMLMTMRGLIEGARSVAYVAAATCDAAHNHADEAVRTKNQALYEFLVPIVKGWST
ELSIDVTSLGVQVHGGMGFIEETGAAQHYRDARILPIYEGTTAIQANDLVGRKTVRDGGAVARAFCASIAETEAALGKHG
GAAFTAVQAQLAKGRAALEAVVEFVVANAKSDPNAVFAGSVPYLKLCGIVFSGWQLGRAMLAADAKRAEDPGFHDAKIAT
AHFFAEHILSQASALRDAIVAGAAPVNAVSPDQF
>Mature_593_residues
TYRAPLKDMLFVMNELAGLDAVSQLPGFEEATPETAQAVLEEAAKFNEQVVAPLNRAGDLDPSSWKDGMVTTTPGFKDAF
RQFGEGGWQGVLHPQEFEGQGLPKLIATACNEMLNSANLSFALCPLLTDGAIEALLTAGSDEQKATFLPKLICGEWTGTM
NLTEPQAGSDLAAVRTRAEPQGDGTYKVFGTKIFITYGEHDMADNIVHLVLARTPNAPEGVKGISLFIVPKFLVNADGSL
GARNDAHCVSIEHKLGIKASPTAVLQFGDHGGAIGTLVGEENRGLEYMFIMMNSARFAVGMQGIAVSERAYQQAVAYARE
RVQSRPVDGSAREAVTIIHHPDVKRMLMTMRGLIEGARSVAYVAAATCDAAHNHADEAVRTKNQALYEFLVPIVKGWSTE
LSIDVTSLGVQVHGGMGFIEETGAAQHYRDARILPIYEGTTAIQANDLVGRKTVRDGGAVARAFCASIAETEAALGKHGG
AAFTAVQAQLAKGRAALEAVVEFVVANAKSDPNAVFAGSVPYLKLCGIVFSGWQLGRAMLAADAKRAEDPGFHDAKIATA
HFFAEHILSQASALRDAIVAGAAPVNAVSPDQF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=318, Percent_Identity=31.1320754716981, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI4557233, Length=422, Percent_Identity=28.9099526066351, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI4501859, Length=407, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI226958412, Length=415, Percent_Identity=25.5421686746988, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI4557235, Length=421, Percent_Identity=28.2660332541568, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI76496475, Length=421, Percent_Identity=28.2660332541568, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI226958414, Length=372, Percent_Identity=26.0752688172043, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI21361497, Length=426, Percent_Identity=25.3521126760563, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=26.3297872340426, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI187960098, Length=313, Percent_Identity=26.517571884984, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI4557231, Length=313, Percent_Identity=26.517571884984, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI87082384, Length=362, Percent_Identity=27.3480662983425, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI87081958, Length=389, Percent_Identity=23.6503856041131, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=429, Percent_Identity=27.5058275058275, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17506239, Length=405, Percent_Identity=28.3950617283951, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71985184, Length=380, Percent_Identity=28.6842105263158, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17569725, Length=414, Percent_Identity=27.0531400966184, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI86563383, Length=339, Percent_Identity=27.7286135693215, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI86563381, Length=339, Percent_Identity=27.7286135693215, Blast_Score=102, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=367, Percent_Identity=27.5204359673025, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17533517, Length=407, Percent_Identity=26.2899262899263, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=27.0053475935829, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=26.9754768392371, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=351, Percent_Identity=26.2108262108262, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=426, Percent_Identity=24.6478873239437, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=304, Percent_Identity=27.9605263157895, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=282, Percent_Identity=27.3049645390071, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=242, Percent_Identity=29.3388429752066, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=299, Percent_Identity=26.4214046822742, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=30.3191489361702, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281363737, Length=406, Percent_Identity=26.8472906403941, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355753, Length=423, Percent_Identity=26.9503546099291, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24666513, Length=414, Percent_Identity=27.0531400966184, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24660351, Length=354, Percent_Identity=27.4011299435028, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=25.4054054054054, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 63124; Mature: 62993

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRAPLKDMLFVMNELAGLDAVSQLPGFEEATPETAQAVLEEAAKFNEQVVAPLNRAGD
CCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCC
LDPSSWKDGMVTTTPGFKDAFRQFGEGGWQGVLHPQEFEGQGLPKLIATACNEMLNSANL
CCCCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
SFALCPLLTDGAIEALLTAGSDEQKATFLPKLICGEWTGTMNLTEPQAGSDLAAVRTRAE
CEEECCHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCC
PQGDGTYKVFGTKIFITYGEHDMADNIVHLVLARTPNAPEGVKGISLFIVPKFLVNADGS
CCCCCEEEEEEEEEEEEECCCHHHHHHHEEEEECCCCCCCCCCCEEEEEEEHHHHCCCCC
LGARNDAHCVSIEHKLGIKASPTAVLQFGDHGGAIGTLVGEENRGLEYMFIMMNSARFAV
CCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEECCCEEEE
GMQGIAVSERAYQQAVAYARERVQSRPVDGSAREAVTIIHHPDVKRMLMTMRGLIEGARS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
VAYVAAATCDAAHNHADEAVRTKNQALYEFLVPIVKGWSTELSIDVTSLGVQVHGGMGFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCH
EETGAAQHYRDARILPIYEGTTAIQANDLVGRKTVRDGGAVARAFCASIAETEAALGKHG
HHCCCHHHHCCCEEEEEECCCCEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCC
GAAFTAVQAQLAKGRAALEAVVEFVVANAKSDPNAVFAGSVPYLKLCGIVFSGWQLGRAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
LAADAKRAEDPGFHDAKIATAHFFAEHILSQASALRDAIVAGAAPVNAVSPDQF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TYRAPLKDMLFVMNELAGLDAVSQLPGFEEATPETAQAVLEEAAKFNEQVVAPLNRAGD
CCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCC
LDPSSWKDGMVTTTPGFKDAFRQFGEGGWQGVLHPQEFEGQGLPKLIATACNEMLNSANL
CCCCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
SFALCPLLTDGAIEALLTAGSDEQKATFLPKLICGEWTGTMNLTEPQAGSDLAAVRTRAE
CEEECCHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCC
PQGDGTYKVFGTKIFITYGEHDMADNIVHLVLARTPNAPEGVKGISLFIVPKFLVNADGS
CCCCCEEEEEEEEEEEEECCCHHHHHHHEEEEECCCCCCCCCCCEEEEEEEHHHHCCCCC
LGARNDAHCVSIEHKLGIKASPTAVLQFGDHGGAIGTLVGEENRGLEYMFIMMNSARFAV
CCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEECCCEEEE
GMQGIAVSERAYQQAVAYARERVQSRPVDGSAREAVTIIHHPDVKRMLMTMRGLIEGARS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
VAYVAAATCDAAHNHADEAVRTKNQALYEFLVPIVKGWSTELSIDVTSLGVQVHGGMGFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCH
EETGAAQHYRDARILPIYEGTTAIQANDLVGRKTVRDGGAVARAFCASIAETEAALGKHG
HHCCCHHHHCCCEEEEEECCCCEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCC
GAAFTAVQAQLAKGRAALEAVVEFVVANAKSDPNAVFAGSVPYLKLCGIVFSGWQLGRAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
LAADAKRAEDPGFHDAKIATAHFFAEHILSQASALRDAIVAGAAPVNAVSPDQF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]