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The map label for this gene is etfA [H]

Identifier: 73542234

GI number: 73542234

Start: 2793935

End: 2794870

Strand: Reverse

Name: etfA [H]

Synonym: Reut_A2549

Alternate gene names: 73542234

Gene position: 2794870-2793935 (Counterclockwise)

Preceding gene: 73542235

Following gene: 73542233

Centisome position: 73.42

GC content: 66.03

Gene sequence:

>936_bases
ATGACTGCACTCGTCATTGCTGAACACGACAATCAATCGATCAAGGCCGCCACGCTGAACACCGTGACGGCAGCTGCCCA
ATGCGGCGGCGATGTCCACGTGCTGGTGGCTGGCGCCAACGCCGCTGCCGCTGCCGCCGCCGCCGCGAAGATCGCCGGCG
TGTCGAAGGTGCTGCTGGCCGACGCCGCCTACTTCGGCGACGGCCTGGCCGAAAACATCGCCGAGCAAGCCCTGGCGATC
GCCAACGACTACAGCCACATCCTGGCTCCGGCTACCCCGTACGGCAAGAACATCCTGCCGCGCGTGGCCGCCAAGCTGGA
CGTGGCCCAGATCTCGGAAATCTCGAAGGTCGACGCTCCGGATACGTTCGAGCGCCCGATCTACGCCGGTAACGCGATCG
CGACCGTGAAGTCGTCGGACAAGATCAAGGTCATCACCGTGCGCGGCACCGCGTTTGACGCTGCTGCCGCCGAAGGCGGT
TCGGCTGCTGTCGAGAACCTGCCGGCCGTGGCCGACGCAGGCGTGTCGCAATTCGTTTCGCGCGAAGTGGCCAAGAGCGA
CCGTCCGGAACTGACCGCCGCCAAGATCATCGTCTCCGGTGGCCGTGGCGTGGGTTCAGGCGAGAACTACACCAAGGTGC
TGACGCCGCTGGCCGACAAGCTGGGTGCCGCGCTGGGCGCTTCGCGCGCTGCCGTGGACGCCGGCTTCGTGCCGAACGAC
TACCAGGTCGGCCAGACCGGCAAGATCGTCGCGCCGCAGCTGTACATCGCCGTCGGTATCTCGGGCGCGATCCAGCACCT
GGCCGGCATGAAGGACTCCAAGGTGATCGTCGCCATAAACAAGGACGCTGAAGCCCCGATCTTCTCGGTGGCTGACTACG
GCCTGGTTGGTGACCTGAACACCGTGGTGCCGGAGCTGGTTGCGGCACTGGGCTGA

Upstream 100 bases:

>100_bases
TGCCAAGCGCAGCGCAGGTGTGATGGTGCCGGACGTTGCGACGCTGGTGCAGAAGCTGAAGAACGAAGCCAAGGTTATCT
GAGCGCGGGGGAGATAGAAC

Downstream 100 bases:

>100_bases
TCTATCGCCGGCCCTTGTGGCCGGCCCTGCAGAGATGCTGCATAAGCCGTTCCGGGCGTGTCCCGCGAACGGCTTTTTTA
TACACGATTGGAGACATCGA

Product: electron transfer flavoprotein beta-subunit:electron transfer flavoprotein, alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTALVIAEHDNQSIKAATLNTVTAAAQCGGDVHVLVAGANAAAAAAAAAKIAGVSKVLLADAAYFGDGLAENIAEQALAI
ANDYSHILAPATPYGKNILPRVAAKLDVAQISEISKVDAPDTFERPIYAGNAIATVKSSDKIKVITVRGTAFDAAAAEGG
SAAVENLPAVADAGVSQFVSREVAKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLVGDLNTVVPELVAALG

Sequences:

>Translated_311_residues
MTALVIAEHDNQSIKAATLNTVTAAAQCGGDVHVLVAGANAAAAAAAAAKIAGVSKVLLADAAYFGDGLAENIAEQALAI
ANDYSHILAPATPYGKNILPRVAAKLDVAQISEISKVDAPDTFERPIYAGNAIATVKSSDKIKVITVRGTAFDAAAAEGG
SAAVENLPAVADAGVSQFVSREVAKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLVGDLNTVVPELVAALG
>Mature_310_residues
TALVIAEHDNQSIKAATLNTVTAAAQCGGDVHVLVAGANAAAAAAAAAKIAGVSKVLLADAAYFGDGLAENIAEQALAIA
NDYSHILAPATPYGKNILPRVAAKLDVAQISEISKVDAPDTFERPIYAGNAIATVKSSDKIKVITVRGTAFDAAAAEGGS
AAVENLPAVADAGVSQFVSREVAKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPNDY
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLVGDLNTVVPELVAALG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=60.128617363344, Blast_Score=360, Evalue=1e-100,
Organism=Homo sapiens, GI189181759, Length=270, Percent_Identity=61.4814814814815, Blast_Score=320, Evalue=9e-88,
Organism=Escherichia coli, GI1786226, Length=236, Percent_Identity=36.4406779661017, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1787990, Length=247, Percent_Identity=34.0080971659919, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082157, Length=245, Percent_Identity=33.8775510204082, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17506929, Length=313, Percent_Identity=56.5495207667732, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6325261, Length=277, Percent_Identity=46.2093862815885, Blast_Score=240, Evalue=2e-64,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=62.6198083067093, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=62.6198083067093, Blast_Score=362, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31252; Mature: 31121

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALVIAEHDNQSIKAATLNTVTAAAQCGGDVHVLVAGANAAAAAAAAAKIAGVSKVLLA
CEEEEEEECCCCCEEEEEHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
DAAYFGDGLAENIAEQALAIANDYSHILAPATPYGKNILPRVAAKLDVAQISEISKVDAP
HHHHHCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCC
DTFERPIYAGNAIATVKSSDKIKVITVRGTAFDAAAAEGGSAAVENLPAVADAGVSQFVS
CCCCCCEECCCEEEEEECCCCEEEEEEECCEECHHHCCCCCHHHHCCCCHHHHHHHHHHH
REVAKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
HHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLVGDLN
CEECCCCCEECCEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCCCCCHH
TVVPELVAALG
HHHHHHHHHCC
>Mature Secondary Structure 
TALVIAEHDNQSIKAATLNTVTAAAQCGGDVHVLVAGANAAAAAAAAAKIAGVSKVLLA
EEEEEEECCCCCEEEEEHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
DAAYFGDGLAENIAEQALAIANDYSHILAPATPYGKNILPRVAAKLDVAQISEISKVDAP
HHHHHCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCC
DTFERPIYAGNAIATVKSSDKIKVITVRGTAFDAAAAEGGSAAVENLPAVADAGVSQFVS
CCCCCCEECCCEEEEEECCCCEEEEEEECCEECHHHCCCCCHHHHCCCCHHHHHHHHHHH
REVAKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
HHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLVGDLN
CEECCCCCEECCEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCCCCCHH
TVVPELVAALG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]