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The map label for this gene is qseC [H]

Identifier: 73541790

GI number: 73541790

Start: 2310306

End: 2311724

Strand: Direct

Name: qseC [H]

Synonym: Reut_A2102

Alternate gene names: 73541790

Gene position: 2310306-2311724 (Clockwise)

Preceding gene: 73541789

Following gene: 73541805

Centisome position: 60.69

GC content: 68.22

Gene sequence:

>1419_bases
ATGAACATGTGGGGCAGGACACCGAGCCTGCGCCTGCAACTGTCGCTGTGGCTGCTACTGCCGCTGCTGGGATTGCTGGC
GCTCGATGCCTGGCTGACCTATGAGCGCGCCATGTCGGCTGCGCACACGGCGTTCGACCGCACGCTCGAGGCATCGCTGC
GCGCCATGCGCGAGGGCATTGCCCTGCGCGACGGCCGGCTCGAGATCGACGTGCCGAACCTGGCACTCGAACTGTTCGAC
GACAAGGCAGGCCCCCACGTCTTCTATCAGGTGCGCGACGAGCACGGCGAGACGGTCACCGGCTACACCGATCTGCCGGG
ACCGCCCGGCACGCGCCCGCCGCTCTACCGAACCGTGTTCTACGACACGGTGTTTCGCGAACAGCCATTGCGCATGGCCG
CGCAGGCGCTGCCAATCCATGACGTGGGCTCGGCCCGCAGCCAGCTGGTGTGGGTCGTGGTGGGCGAAACCATCGAACCG
CGCCAGGCGTTGGCGCGCGAGATCCTGGTGGGCTCGCTGCTGCAGGAACTGGTGCTGGTAGCGCTGGCGCTCGGCATCGT
CTGGCTGGGCGTGCGCCGCGGGCTGCGGCCACTGCATCGCTTGTCGGATACGGTGGCGGCGCGCAGCGCGAGCCAGCTCG
ACCCGATCGAGCATCGTGACCTGCCGTCCGAAATGAAGCCGCTGGTGCGCGCGCTGAACCAGTACGTGGATCGCCTGCAC
CGCATGCTGCAGGCACGCAAGCGCTTCTTCGCCGATGCCGCGCATCAGCTCAAGACGCCGCTCGCCGTGATCCAGGCCGA
ATCCGAACTGGCGTTGCGCGAGCCCGATGGCGAGCGCGTGCGCGAACACATGCGCCTGCTGCACGGCACCGTGCGCCATG
CAGCCAAGGGGGTGCAGCAATTGCTGTCGCTGTCCAGGCTCGATCCGGACAGCGGCTACGCGCCCACGCTGCGCGACGTG
CCGCTCGATGCCGCTGCGCGAGCGGTGGCACTGGAATGGGTGTCGGTCGCACGCCGGCATGGCGTGGACCTGGGATTTGA
AGGCGATGACACCGTCACGGTGCAGGGGCAGATGGAACTGCTGCAGGAACTTACCGGCAACCTGATCGACAACGCGATCC
GCTATGCGGGCGACGGATCGACTGTCACGGTTCGGGTGGCGCAGGAAGCGGACGGCACCGCCCAGCTGCAGGTGATCGAC
GACGGTCCCGGCATTGCCTCCGCCGAACGCGAAGACGTTTTCCGACGCTTCTACCGTGGCGAAAGCGGCCAAGGCGTGGA
AGGCACCGGGTTAGGGCTGCCGATTGTCAGGGAGATCGCCAGGCTGCATCAGGCCACTGCCGGCCTCGACGACACGCCCG
GCGGCGGGCTCACCGTGACGGTGCGCTTTCCCGCGCCGGGTGGCGAGCCGCAGGCCTAG

Upstream 100 bases:

>100_bases
ACATCCACCGCCTGCGCAAGAAGCTCGATGGCAGCGGCGTGGCGATCGTCACGCTGCGTGGGCTCGGCTATCTGATCGAA
GCGCGGCCACAGCCTGCGCC

Downstream 100 bases:

>100_bases
TCCATCTTCAGAGCTTCTCGGTCTCGCCGATCTTCGGCTGCCATTTCATCAGCCGCTTTTCACCGGCGCCGACCATCCAG
TCCAGCACCAGCGCAAACGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MNMWGRTPSLRLQLSLWLLLPLLGLLALDAWLTYERAMSAAHTAFDRTLEASLRAMREGIALRDGRLEIDVPNLALELFD
DKAGPHVFYQVRDEHGETVTGYTDLPGPPGTRPPLYRTVFYDTVFREQPLRMAAQALPIHDVGSARSQLVWVVVGETIEP
RQALAREILVGSLLQELVLVALALGIVWLGVRRGLRPLHRLSDTVAARSASQLDPIEHRDLPSEMKPLVRALNQYVDRLH
RMLQARKRFFADAAHQLKTPLAVIQAESELALREPDGERVREHMRLLHGTVRHAAKGVQQLLSLSRLDPDSGYAPTLRDV
PLDAAARAVALEWVSVARRHGVDLGFEGDDTVTVQGQMELLQELTGNLIDNAIRYAGDGSTVTVRVAQEADGTAQLQVID
DGPGIASAEREDVFRRFYRGESGQGVEGTGLGLPIVREIARLHQATAGLDDTPGGGLTVTVRFPAPGGEPQA

Sequences:

>Translated_472_residues
MNMWGRTPSLRLQLSLWLLLPLLGLLALDAWLTYERAMSAAHTAFDRTLEASLRAMREGIALRDGRLEIDVPNLALELFD
DKAGPHVFYQVRDEHGETVTGYTDLPGPPGTRPPLYRTVFYDTVFREQPLRMAAQALPIHDVGSARSQLVWVVVGETIEP
RQALAREILVGSLLQELVLVALALGIVWLGVRRGLRPLHRLSDTVAARSASQLDPIEHRDLPSEMKPLVRALNQYVDRLH
RMLQARKRFFADAAHQLKTPLAVIQAESELALREPDGERVREHMRLLHGTVRHAAKGVQQLLSLSRLDPDSGYAPTLRDV
PLDAAARAVALEWVSVARRHGVDLGFEGDDTVTVQGQMELLQELTGNLIDNAIRYAGDGSTVTVRVAQEADGTAQLQVID
DGPGIASAEREDVFRRFYRGESGQGVEGTGLGLPIVREIARLHQATAGLDDTPGGGLTVTVRFPAPGGEPQA
>Mature_472_residues
MNMWGRTPSLRLQLSLWLLLPLLGLLALDAWLTYERAMSAAHTAFDRTLEASLRAMREGIALRDGRLEIDVPNLALELFD
DKAGPHVFYQVRDEHGETVTGYTDLPGPPGTRPPLYRTVFYDTVFREQPLRMAAQALPIHDVGSARSQLVWVVVGETIEP
RQALAREILVGSLLQELVLVALALGIVWLGVRRGLRPLHRLSDTVAARSASQLDPIEHRDLPSEMKPLVRALNQYVDRLH
RMLQARKRFFADAAHQLKTPLAVIQAESELALREPDGERVREHMRLLHGTVRHAAKGVQQLLSLSRLDPDSGYAPTLRDV
PLDAAARAVALEWVSVARRHGVDLGFEGDDTVTVQGQMELLQELTGNLIDNAIRYAGDGSTVTVRVAQEADGTAQLQVID
DGPGIASAEREDVFRRFYRGESGQGVEGTGLGLPIVREIARLHQATAGLDDTPGGGLTVTVRFPAPGGEPQA

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=314, Percent_Identity=32.8025477707006, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1790551, Length=300, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788279, Length=339, Percent_Identity=26.2536873156342, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1786783, Length=304, Percent_Identity=27.9605263157895, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=30.5454545454545, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786600, Length=256, Percent_Identity=30.859375, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789808, Length=297, Percent_Identity=27.9461279461279, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790346, Length=280, Percent_Identity=28.9285714285714, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787894, Length=309, Percent_Identity=27.5080906148867, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=305, Percent_Identity=28.5245901639344, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788713, Length=282, Percent_Identity=21.2765957446809, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787374, Length=301, Percent_Identity=25.5813953488372, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=249, Percent_Identity=26.9076305220884, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=26.8398268398268, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=26.6094420600858, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=23.9669421487603, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=23.9130434782609, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=25.8928571428571, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51873; Mature: 51873

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMWGRTPSLRLQLSLWLLLPLLGLLALDAWLTYERAMSAAHTAFDRTLEASLRAMREGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ALRDGRLEIDVPNLALELFDDKAGPHVFYQVRDEHGETVTGYTDLPGPPGTRPPLYRTVF
EEECCEEEEECCHHHHHHHCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHH
YDTVFREQPLRMAAQALPIHDVGSARSQLVWVVVGETIEPRQALAREILVGSLLQELVLV
HHHHHHHCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
ALALGIVWLGVRRGLRPLHRLSDTVAARSASQLDPIEHRDLPSEMKPLVRALNQYVDRLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHH
RMLQARKRFFADAAHQLKTPLAVIQAESELALREPDGERVREHMRLLHGTVRHAAKGVQQ
HHHHHHHHHHHHHHHHHHCCHHEEECCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LLSLSRLDPDSGYAPTLRDVPLDAAARAVALEWVSVARRHGVDLGFEGDDTVTVQGQMEL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHH
LQELTGNLIDNAIRYAGDGSTVTVRVAQEADGTAQLQVIDDGPGIASAEREDVFRRFYRG
HHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHCC
ESGQGVEGTGLGLPIVREIARLHQATAGLDDTPGGGLTVTVRFPAPGGEPQA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MNMWGRTPSLRLQLSLWLLLPLLGLLALDAWLTYERAMSAAHTAFDRTLEASLRAMREGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ALRDGRLEIDVPNLALELFDDKAGPHVFYQVRDEHGETVTGYTDLPGPPGTRPPLYRTVF
EEECCEEEEECCHHHHHHHCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHH
YDTVFREQPLRMAAQALPIHDVGSARSQLVWVVVGETIEPRQALAREILVGSLLQELVLV
HHHHHHHCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
ALALGIVWLGVRRGLRPLHRLSDTVAARSASQLDPIEHRDLPSEMKPLVRALNQYVDRLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHH
RMLQARKRFFADAAHQLKTPLAVIQAESELALREPDGERVREHMRLLHGTVRHAAKGVQQ
HHHHHHHHHHHHHHHHHHCCHHEEECCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LLSLSRLDPDSGYAPTLRDVPLDAAARAVALEWVSVARRHGVDLGFEGDDTVTVQGQMEL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHH
LQELTGNLIDNAIRYAGDGSTVTVRVAQEADGTAQLQVIDDGPGIASAEREDVFRRFYRG
HHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHCC
ESGQGVEGTGLGLPIVREIARLHQATAGLDDTPGGGLTVTVRFPAPGGEPQA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]