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The map label for this gene is tctD [H]

Identifier: 73541789

GI number: 73541789

Start: 2309629

End: 2310309

Strand: Direct

Name: tctD [H]

Synonym: Reut_A2101

Alternate gene names: 73541789

Gene position: 2309629-2310309 (Clockwise)

Preceding gene: 73541787

Following gene: 73541790

Centisome position: 60.68

GC content: 64.46

Gene sequence:

>681_bases
ATGCGTATCCTGCTTGCCGAAGACAACCTGATGCTGGCCAACTCGCTGACCCAGGCCATGACCCAGGCCGGGTTTACCGT
CGACTGCATGCACGACGGCCGTAGCGCCGACCACCTGCTGGCCACGCAGGACTATGCGTTGCTGATCCTCGATCTCGGCT
TGCCACGGCTGGACGGTCTTGAAGTGCTGCGCCGGCTGCGCCAACGCCGCAACCGCATGCCTGTGCTCATCCTGACCGCG
CATGGCTCGGTGGAGGACCGCGTGCGCGGTCTGGACCTGGGCGCCGACGACTACCTGGCCAAGCCCTTTGACCTTTCCGA
GCTAGAAGCGCGCGCACGCGCGCTGATCCGCCGCAGCCACGGCCATGAATCCACACAGCTGAGTTGCGGCCCCCTGCACT
ACGACAGCGTGAGCCGCGCGTTCACGATCGACGGCGAACTGCTGCAACTCACGCGGCGCGAGCGATCGGTGCTCGAAGTG
CTGTTGCTGCGTAATGGCAAGGCCGTCAACAAGTCAGCCCTCTCCGAGAAGATCTTCGGCATTGACGAGTCGGTCAATCC
GGATGCCATCGAGATCTACATCCACCGCCTGCGCAAGAAGCTCGATGGCAGCGGCGTGGCGATCGTCACGCTGCGTGGGC
TCGGCTATCTGATCGAAGCGCGGCCACAGCCTGCGCCATGA

Upstream 100 bases:

>100_bases
CGGACATGCACGCCTGGGCGCACGGCTATTGGGCCGGTGCAGCAAGCGCCGCCTTGCCCGTCCCGCAGCGCTGCCTGCCT
TGCCGCTTTGAATTACCCCG

Downstream 100 bases:

>100_bases
ACATGTGGGGCAGGACACCGAGCCTGCGCCTGCAACTGTCGCTGTGGCTGCTACTGCCGCTGCTGGGATTGCTGGCGCTC
GATGCCTGGCTGACCTATGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRILLAEDNLMLANSLTQAMTQAGFTVDCMHDGRSADHLLATQDYALLILDLGLPRLDGLEVLRRLRQRRNRMPVLILTA
HGSVEDRVRGLDLGADDYLAKPFDLSELEARARALIRRSHGHESTQLSCGPLHYDSVSRAFTIDGELLQLTRRERSVLEV
LLLRNGKAVNKSALSEKIFGIDESVNPDAIEIYIHRLRKKLDGSGVAIVTLRGLGYLIEARPQPAP

Sequences:

>Translated_226_residues
MRILLAEDNLMLANSLTQAMTQAGFTVDCMHDGRSADHLLATQDYALLILDLGLPRLDGLEVLRRLRQRRNRMPVLILTA
HGSVEDRVRGLDLGADDYLAKPFDLSELEARARALIRRSHGHESTQLSCGPLHYDSVSRAFTIDGELLQLTRRERSVLEV
LLLRNGKAVNKSALSEKIFGIDESVNPDAIEIYIHRLRKKLDGSGVAIVTLRGLGYLIEARPQPAP
>Mature_226_residues
MRILLAEDNLMLANSLTQAMTQAGFTVDCMHDGRSADHLLATQDYALLILDLGLPRLDGLEVLRRLRQRRNRMPVLILTA
HGSVEDRVRGLDLGADDYLAKPFDLSELEARARALIRRSHGHESTQLSCGPLHYDSVSRAFTIDGELLQLTRRERSVLEV
LLLRNGKAVNKSALSEKIFGIDESVNPDAIEIYIHRLRKKLDGSGVAIVTLRGLGYLIEARPQPAP

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=41.743119266055, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=42.6605504587156, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=39.4618834080717, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=39.9103139013453, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=39.0134529147982, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=33.0396475770925, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=38.4279475982533, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790860, Length=219, Percent_Identity=31.9634703196347, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=32.4444444444444, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=33.4801762114537, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=31.7180616740088, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=30.3964757709251, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=30.3571428571429, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788550, Length=144, Percent_Identity=35.4166666666667, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=33.0645161290323, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788713, Length=120, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=31.3559322033898, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787487, Length=119, Percent_Identity=32.7731092436975, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25180; Mature: 25180

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLAEDNLMLANSLTQAMTQAGFTVDCMHDGRSADHLLATQDYALLILDLGLPRLDGL
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCEEEEEECCCCCCCHH
EVLRRLRQRRNRMPVLILTAHGSVEDRVRGLDLGADDYLAKPFDLSELEARARALIRRSH
HHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHC
GHESTQLSCGPLHYDSVSRAFTIDGELLQLTRRERSVLEVLLLRNGKAVNKSALSEKIFG
CCCCCEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
IDESVNPDAIEIYIHRLRKKLDGSGVAIVTLRGLGYLIEARPQPAP
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCC
>Mature Secondary Structure
MRILLAEDNLMLANSLTQAMTQAGFTVDCMHDGRSADHLLATQDYALLILDLGLPRLDGL
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCEEEEEECCCCCCCHH
EVLRRLRQRRNRMPVLILTAHGSVEDRVRGLDLGADDYLAKPFDLSELEARARALIRRSH
HHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHC
GHESTQLSCGPLHYDSVSRAFTIDGELLQLTRRERSVLEVLLLRNGKAVNKSALSEKIFG
CCCCCEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
IDESVNPDAIEIYIHRLRKKLDGSGVAIVTLRGLGYLIEARPQPAP
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]