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The map label for this gene is qor [H]

Identifier: 73541787

GI number: 73541787

Start: 2306924

End: 2307898

Strand: Direct

Name: qor [H]

Synonym: Reut_A2099

Alternate gene names: 73541787

Gene position: 2306924-2307898 (Clockwise)

Preceding gene: 73541781

Following gene: 73541789

Centisome position: 60.6

GC content: 64.82

Gene sequence:

>975_bases
ATGAAAGCCGTACTGTGCAAGGCCTGGGGGCCGCCCGATTCCCTGACCGTCGAAACCCTGCCGGATCCGGTGCCGGATCA
GGGCGAAGTGGTCATCGAGGTAAAGGCCGCCGGCGTGAATTTCCCGGATGTGCTCATCATCCAGAACAAATACCAGGCCA
AGCCGGAACTGCCGTTCACGCCGGGCTCGGAACTGGCGGGCATCGTGACTGCCGTTGGCGCGGGCGTCACGCACGTCAAG
CCCGGCGACAACGTCATTGCGTATCTCGGCAACGGCGCATTCGCTTCGCACGTGAAGGCGCCGGCCAACAAGGTCGTGCC
CATGCCGCCCGGCGTGGATTACGAAACCGCGGCAGCATTCACCCTTACCTACGGCACCTCGCACCACGCCGTCGTCGACC
GTGGCGAACTCAAGGCCGGACAGACCATGCTGGTGCTCGGCGCAGCTGGCGGCGTGGGGCTTGCCGCGATTGAAATCGGC
AAGGCCATCGGCGCGCGCGTCATCGCGGCGGCGTCGACCGATGAAAAGCTCGCAGTTTGCAAGGAACACGGCGCCGATGC
GCTGATCAACTACAGCACCGAAGACCTGCGCGAACGCGTCAAGGCGCTGACCGATGGCAACGGTCCGGACGTGATCTACG
ACCCTGTGGGTGGCGTCTATGCCGAACCGGCGTTCCGCTCGATCGCATGGCGGGGCCGCTATCTGGTGGTGGGCTTCGCC
AATGGCGAGATCCCGAAGATTCCGCTGAACCTGGCGCTGCTCAAGGGGGCTTCGCTCGTGGGCGTGTTCTGGGGCGATTT
CGTGCGGCGCGAACCGCGTGCGAACCAGGCCAATATGGCGCAAATGCTTGGCTGGATGAAGGAAGGCAAGCTGCGCCCGC
ACATCTCCGCGCGCTACCCGCTGGAGCAGGCTCCGCAGGCGCTCAAGGACATGGAAGCGCGCAAGGTGACCGGCAAGGTG
GTGATCGTTCCCTGA

Upstream 100 bases:

>100_bases
AGAACGATCGTGCTATTTGCGTTACACTTGGTCTTGCCGTCTCGCCGCGCGCGGCGGCACACGGCACGATTACCCGCCCA
TACATATCACCGGAGACATG

Downstream 100 bases:

>100_bases
ACAGGCGCCACAAAAAATAAGGACGCAGAGCGTGCGGCAACGCTCTGCATCCCCTGCTGGGGCAATACGCCCCAAGCTGT
CTTCCACCTTCACGCACACC

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKAVLCKAWGPPDSLTVETLPDPVPDQGEVVIEVKAAGVNFPDVLIIQNKYQAKPELPFTPGSELAGIVTAVGAGVTHVK
PGDNVIAYLGNGAFASHVKAPANKVVPMPPGVDYETAAAFTLTYGTSHHAVVDRGELKAGQTMLVLGAAGGVGLAAIEIG
KAIGARVIAAASTDEKLAVCKEHGADALINYSTEDLRERVKALTDGNGPDVIYDPVGGVYAEPAFRSIAWRGRYLVVGFA
NGEIPKIPLNLALLKGASLVGVFWGDFVRREPRANQANMAQMLGWMKEGKLRPHISARYPLEQAPQALKDMEARKVTGKV
VIVP

Sequences:

>Translated_324_residues
MKAVLCKAWGPPDSLTVETLPDPVPDQGEVVIEVKAAGVNFPDVLIIQNKYQAKPELPFTPGSELAGIVTAVGAGVTHVK
PGDNVIAYLGNGAFASHVKAPANKVVPMPPGVDYETAAAFTLTYGTSHHAVVDRGELKAGQTMLVLGAAGGVGLAAIEIG
KAIGARVIAAASTDEKLAVCKEHGADALINYSTEDLRERVKALTDGNGPDVIYDPVGGVYAEPAFRSIAWRGRYLVVGFA
NGEIPKIPLNLALLKGASLVGVFWGDFVRREPRANQANMAQMLGWMKEGKLRPHISARYPLEQAPQALKDMEARKVTGKV
VIVP
>Mature_324_residues
MKAVLCKAWGPPDSLTVETLPDPVPDQGEVVIEVKAAGVNFPDVLIIQNKYQAKPELPFTPGSELAGIVTAVGAGVTHVK
PGDNVIAYLGNGAFASHVKAPANKVVPMPPGVDYETAAAFTLTYGTSHHAVVDRGELKAGQTMLVLGAAGGVGLAAIEIG
KAIGARVIAAASTDEKLAVCKEHGADALINYSTEDLRERVKALTDGNGPDVIYDPVGGVYAEPAFRSIAWRGRYLVVGFA
NGEIPKIPLNLALLKGASLVGVFWGDFVRREPRANQANMAQMLGWMKEGKLRPHISARYPLEQAPQALKDMEARKVTGKV
VIVP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=30.9815950920245, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=30.9815950920245, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=30.5466237942122, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI22538446, Length=335, Percent_Identity=30.4477611940298, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI22538444, Length=335, Percent_Identity=30.4477611940298, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI194239676, Length=326, Percent_Identity=29.1411042944785, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI28557745, Length=321, Percent_Identity=30.2180685358255, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI24308257, Length=346, Percent_Identity=25.7225433526012, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI47519420, Length=333, Percent_Identity=28.8288288288288, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI67078404, Length=290, Percent_Identity=26.8965517241379, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI197927207, Length=192, Percent_Identity=30.2083333333333, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI67078406, Length=283, Percent_Identity=27.208480565371, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI41872631, Length=302, Percent_Identity=24.8344370860927, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI226059159, Length=208, Percent_Identity=27.8846153846154, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI226059133, Length=208, Percent_Identity=27.8846153846154, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1790485, Length=320, Percent_Identity=32.5, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI87081918, Length=328, Percent_Identity=25, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI226510941, Length=208, Percent_Identity=29.8076923076923, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=323, Percent_Identity=27.5541795665635, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17536829, Length=310, Percent_Identity=27.0967741935484, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI133901712, Length=282, Percent_Identity=26.5957446808511, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI133901710, Length=288, Percent_Identity=26.3888888888889, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=325, Percent_Identity=33.2307692307692, Blast_Score=145, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6324486, Length=337, Percent_Identity=24.6290801186944, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=337, Percent_Identity=24.0356083086053, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=337, Percent_Identity=23.1454005934718, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=335, Percent_Identity=22.9850746268657, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24581345, Length=250, Percent_Identity=26, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19920632, Length=311, Percent_Identity=24.7588424437299, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI221330659, Length=311, Percent_Identity=24.7588424437299, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34200; Mature: 34200

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLCKAWGPPDSLTVETLPDPVPDQGEVVIEVKAAGVNFPDVLIIQNKYQAKPELPFT
CCEEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCC
PGSELAGIVTAVGAGVTHVKPGDNVIAYLGNGAFASHVKAPANKVVPMPPGVDYETAAAF
CCHHHHHHHHHHCCCCEEECCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCEEEE
TLTYGTSHHAVVDRGELKAGQTMLVLGAAGGVGLAAIEIGKAIGARVIAAASTDEKLAVC
EEEECCCCCEEEECCCCCCCCEEEEEECCCCCEEEHHHHHHHHCCEEEEECCCCCHHHHH
KEHGADALINYSTEDLRERVKALTDGNGPDVIYDPVGGVYAEPAFRSIAWRGRYLVVGFA
HHCCCCEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHEECCCEEEEEEC
NGEIPKIPLNLALLKGASLVGVFWGDFVRREPRANQANMAQMLGWMKEGKLRPHISARYP
CCCCCCCCEEEEEECCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
LEQAPQALKDMEARKVTGKVVIVP
HHHHHHHHHHHHHHHHCCEEEEEC
>Mature Secondary Structure
MKAVLCKAWGPPDSLTVETLPDPVPDQGEVVIEVKAAGVNFPDVLIIQNKYQAKPELPFT
CCEEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCC
PGSELAGIVTAVGAGVTHVKPGDNVIAYLGNGAFASHVKAPANKVVPMPPGVDYETAAAF
CCHHHHHHHHHHCCCCEEECCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCEEEE
TLTYGTSHHAVVDRGELKAGQTMLVLGAAGGVGLAAIEIGKAIGARVIAAASTDEKLAVC
EEEECCCCCEEEECCCCCCCCEEEEEECCCCCEEEHHHHHHHHCCEEEEECCCCCHHHHH
KEHGADALINYSTEDLRERVKALTDGNGPDVIYDPVGGVYAEPAFRSIAWRGRYLVVGFA
HHCCCCEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHEECCCEEEEEEC
NGEIPKIPLNLALLKGASLVGVFWGDFVRREPRANQANMAQMLGWMKEGKLRPHISARYP
CCCCCCCCEEEEEECCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
LEQAPQALKDMEARKVTGKVVIVP
HHHHHHHHHHHHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]