BacMap

Definition	Ralstonia eutropha JMP134 chromosome 1, complete sequence.
Accession	NC_007347
Length	3,806,533

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The map label for this gene is fabG [H]

Identifier: 73541517

GI number: 73541517

Start: 2003551

End: 2004351

Strand: Direct

Name: fabG [H]

Synonym: Reut_A1828

Alternate gene names: 73541517

Gene position: 2003551-2004351 (Clockwise)

Preceding gene: 73541516

Following gene: 73541527

Centisome position: 52.63

GC content: 70.54

Gene sequence:

>801_bases
ATGAAGAATCTTGAAGGCAAGGTGGCGATCGTCACCGGCGGCACCGGCGGGATCGGCCGGGGCGTGGCACTGCAGCTCGC
GGCGCGCGGGGCGCTGGTGGTCATCAGCGGCAGGAGCGCGTCAAAGGCGGACGCGGTGCTCGCCGAACTGCGCGAGGCGG
GCGGCCAGGGCGATTTCATCCCCGGCGACGTCCGCGTGAAGGCCGACATGGATGCGCTCGCCGCCGAGACCGCGCGCCGC
CACGGCGGCATCGATATCGTGGTCGCCAATGCCGGCGGCAACGACGACGAGGCGCGCCGCCCGGAAGTGCGCGGGCCGTT
TGGCGATATCGACGTCGCGCGCGTCTGCGCCGTGGTGGCGGAGAACACCGCCGCGAAGCTGCTGCCGGTGCAGTCGGCCC
TGCCCTTCCTGCGCGAGCGCGGCGGCGGCGCGGTGGTCTTCGTGACCTCGGAAGGTGGGCGCGTGCCGACGCCGACGCAG
ACCGCGGTGGCCACCTTTGCCGGCGGCCTGATCAGCGCAAGCAAGGTGCTATCGAAGGAACTCGCGCGCGACCGCATCCG
CGTGAACTGTGTATGCGTGACGGTGGTGCGCGACAGTCCCTCCTGGAAGGCCGCGTTCGAGCGCACCGATGGCGTGTCGG
ACCGGCACCGCAAGCAGTACGAGAAAATCATCGCCAGCAGCCCGCTCGGCGTGGCAAGCCCGGAGGATATCGGCCAGGTG
GTGGCTTTCCTCGCCTCCGACGAGTCGCGCTACCTGACTGGGGCGACCATCAGCCCGACCGGCGGGCTGACGATTCACTG
A

Upstream 100 bases:

>100_bases
TGCGCGACTGGCTACACCTCGATGCGCGGCAGGTCGCCGCGCTGCGCGCCGACGGCATCGTCTGACCGGAAGACAGTGAA
AGCACAGCAAGGAACCAGCA

Downstream 100 bases:

>100_bases
CGATCTGCTGAAGACCGGCTGCGCGGCCCGCCGCCTCACACAATGGCGCCGGCCGCGCGCAATGCCGCAATGTCAGGTGC
GCTGAAGCCCCAGTCGCCTA

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKNLEGKVAIVTGGTGGIGRGVALQLAARGALVVISGRSASKADAVLAELREAGGQGDFIPGDVRVKADMDALAAETARR
HGGIDIVVANAGGNDDEARRPEVRGPFGDIDVARVCAVVAENTAAKLLPVQSALPFLRERGGGAVVFVTSEGGRVPTPTQ
TAVATFAGGLISASKVLSKELARDRIRVNCVCVTVVRDSPSWKAAFERTDGVSDRHRKQYEKIIASSPLGVASPEDIGQV
VAFLASDESRYLTGATISPTGGLTIH

Sequences:

>Translated_266_residues
MKNLEGKVAIVTGGTGGIGRGVALQLAARGALVVISGRSASKADAVLAELREAGGQGDFIPGDVRVKADMDALAAETARR
HGGIDIVVANAGGNDDEARRPEVRGPFGDIDVARVCAVVAENTAAKLLPVQSALPFLRERGGGAVVFVTSEGGRVPTPTQ
TAVATFAGGLISASKVLSKELARDRIRVNCVCVTVVRDSPSWKAAFERTDGVSDRHRKQYEKIIASSPLGVASPEDIGQV
VAFLASDESRYLTGATISPTGGLTIH
>Mature_266_residues
MKNLEGKVAIVTGGTGGIGRGVALQLAARGALVVISGRSASKADAVLAELREAGGQGDFIPGDVRVKADMDALAAETARR
HGGIDIVVANAGGNDDEARRPEVRGPFGDIDVARVCAVVAENTAAKLLPVQSALPFLRERGGGAVVFVTSEGGRVPTPTQ
TAVATFAGGLISASKVLSKELARDRIRVNCVCVTVVRDSPSWKAAFERTDGVSDRHRKQYEKIIASSPLGVASPEDIGQV
VAFLASDESRYLTGATISPTGGLTIH

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=32.0610687022901, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI126723750, Length=276, Percent_Identity=29.7101449275362, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=28.2945736434109, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI19923817, Length=280, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=33.1658291457286, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40254992, Length=260, Percent_Identity=28.8461538461538, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=32.4468085106383, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI32455239, Length=200, Percent_Identity=28.5, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031765, Length=200, Percent_Identity=28.5, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI15277342, Length=275, Percent_Identity=30.1818181818182, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=29.6610169491525, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=264, Percent_Identity=29.9242424242424, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI87082100, Length=275, Percent_Identity=30.9090909090909, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=26.4367816091954, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=28.2442748091603, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790717, Length=266, Percent_Identity=25.187969924812, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789208, Length=266, Percent_Identity=27.8195488721804, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367175, Length=262, Percent_Identity=25.1908396946565, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=30.5343511450382, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=267, Percent_Identity=31.4606741573034, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=29.520295202952, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=279, Percent_Identity=31.8996415770609, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=29.9270072992701, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=30.6569343065693, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=276, Percent_Identity=29.3478260869565, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=277, Percent_Identity=27.0758122743682, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=278, Percent_Identity=29.8561151079137, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=28.9377289377289, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=273, Percent_Identity=27.4725274725275, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=278, Percent_Identity=31.6546762589928, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=26.9372693726937, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=27.8388278388278, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=26.8115942028986, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=205, Percent_Identity=31.7073170731707, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=292, Percent_Identity=27.3972602739726, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=291, Percent_Identity=29.8969072164948, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=268, Percent_Identity=26.4925373134328, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=286, Percent_Identity=27.972027972028, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=271, Percent_Identity=28.0442804428044, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=268, Percent_Identity=25.7462686567164, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=269, Percent_Identity=27.5092936802974, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=24.7474747474747, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355319, Length=265, Percent_Identity=33.9622641509434, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI23397609, Length=263, Percent_Identity=30.4182509505703, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644339, Length=264, Percent_Identity=27.6515151515151, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639444, Length=266, Percent_Identity=30.0751879699248, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21357041, Length=266, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571526, Length=274, Percent_Identity=26.2773722627737, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27466; Mature: 27466

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLEGKVAIVTGGTGGIGRGVALQLAARGALVVISGRSASKADAVLAELREAGGQGDFI
CCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
PGDVRVKADMDALAAETARRHGGIDIVVANAGGNDDEARRPEVRGPFGDIDVARVCAVVA
CCCEEEEECHHHHHHHHHHHCCCEEEEEECCCCCCCHHCCCCCCCCCCCCHHHHHHHHHH
ENTAAKLLPVQSALPFLRERGGGAVVFVTSEGGRVPTPTQTAVATFAGGLISASKVLSKE
CCCHHHEEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LARDRIRVNCVCVTVVRDSPSWKAAFERTDGVSDRHRKQYEKIIASSPLGVASPEDIGQV
HHHCCEEEEEEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
VAFLASDESRYLTGATISPTGGLTIH
HHHHHCCCCCEEECCEECCCCCEEEC
>Mature Secondary Structure
MKNLEGKVAIVTGGTGGIGRGVALQLAARGALVVISGRSASKADAVLAELREAGGQGDFI
CCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
PGDVRVKADMDALAAETARRHGGIDIVVANAGGNDDEARRPEVRGPFGDIDVARVCAVVA
CCCEEEEECHHHHHHHHHHHCCCEEEEEECCCCCCCHHCCCCCCCCCCCCHHHHHHHHHH
ENTAAKLLPVQSALPFLRERGGGAVVFVTSEGGRVPTPTQTAVATFAGGLISASKVLSKE
CCCHHHEEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LARDRIRVNCVCVTVVRDSPSWKAAFERTDGVSDRHRKQYEKIIASSPLGVASPEDIGQV
HHHCCEEEEEEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
VAFLASDESRYLTGATISPTGGLTIH
HHHHHCCCCCEEECCEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]