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The map label for this gene is livM [C]

Identifier: 73540691

GI number: 73540691

Start: 1077409

End: 1078623

Strand: Direct

Name: livM [C]

Synonym: Reut_A0988

Alternate gene names: 73540691

Gene position: 1077409-1078623 (Clockwise)

Preceding gene: 73540690

Following gene: 73540692

Centisome position: 28.3

GC content: 64.03

Gene sequence:

>1215_bases
ATGCAGAGCTTTCACTCAAACTCCCCGGGCACGCCGTTTCGTCTGTCGGTGCCCGAGCGCCAGCCGCTGTTCACTGGGCG
CGGCTGGGCTGTGCTGGCGATGCTGACGCTCGTCGTGGCGGTCGGCGTTCCGGTGTGCGCGCTGATGGTGCCGGAAGGGC
ATCCGCTTCACCTGTCGGCCTATGCACTGACGCTGATCGGCAAGATCATGTGCTTCGCGCTGGCTGCCATCGCACTCGAT
CTCGTGTGGGGCTACTGCGGCATCCTGAGCCTTGGACATGGCTTGTTCTTTGCGCTTGGCGGCTATGCGATGGGCATGTA
CCTGATGCGATCCATCGGCCGCGAAGGCGTGTATAAGAGCGACTTGCCGGACTTCATGGTGTTCCTCGACTGGAAGGAAC
TGCCGTGGTTCTGGCACGGCACCGAACACCTCTGGTATGCGCTGCTGCTGGTGGTGCTCGTGCCCGGCGTGCTGGCGTGG
CTGTTCGGCTTCTTCGCGTTCCGTTCGCGCATCAAGGGCGTGTACCTGTCGATCATCACGCAAGCCATGACGTATGCGGC
GATGCTGCTTTTCTTCCGCAACGAGACCGGCTTCGGCGGCAACAACGGGTTCACTGACTTCAAGCGCATCGCGGATTTCG
CGATCGCCGCGCCGCAGACGCGCACGGCGCTGTTCGTGCTGACGTTCCTCGCACTGATCGCCGGGTTCGTCGCGTGCCGC
TATATCGTGACGTCGAAGCTGGGCCGCGTGGTCACGGCCGTGCGCGATGCCGAGATGCGCGTGATGTTCTCGGGCTACAA
CCCGCTCGGCTACAAGCTCTTCGTATGGACGTTCTCGGCCGTGCTGTGCGGTGTTGCGGGCGCGCTGTATGTGCCGCAGG
TGGGCATCATCAACCCGGGCGAGATGTCGCCGGGCAATTCGATCGAGATGGCCGTATGGGTGGCCGTTGGTGGCCGCGGC
ACGTTGATCGGGCCCGTGATCGGGGCGTTCCTGGTCAATGGCGCCAAGACGATGTTCACCGCGTACTTTGCCGAGTACTG
GCTGTTCCTCCTCGGCGCGATGTTCGTGCTCGTCACGCTGTACCTGCCGGATGGCGTGATCGGGTTGTGGAAGCGTCTGC
GCCAACGCGGCAGCCGTGCCACGCCGGCAGTGGCCGCGCCGACCGAGGCCGTATCCAGTCCTGCAGTAGCAGGACGCACC
GGAGGTGAAGCATGA

Upstream 100 bases:

>100_bases
CGGTGCTCGCCAAGATCTTCGTCCTGGTGCTGATCGTGCTTTTCATCCAGAAGCGCCCGCAGGGACTTTTCGCGCTCAAG
GGGCGCAGCGCGGAGGCATG

Downstream 100 bases:

>100_bases
ATGCCGCGCTCGAATACGGTCAGGCGGAAAGCGGCAATGCCACGGGCCTTGGCCGCGTAGTGGAGCCGGGCACGATCGAT
GTCTCGCATGGCCCCATCCT

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: Inner-Membrane Translocator; Branched-Chain Amino Acid ABC Transporter Permease Protein; ABC Transporter Permease Protein; Urea ABC Transporter Permease UrtC; Amino Acid Or Sugar ABC Transport System Permease Protein; Branched Chain Amino Acid ABC Transporter Permease; Branched-Chain Amino Acid Transport System Permease Protein; Branched-Chain Amino Acid ABC Transporter Permease; ABC Transporter Permease; ABC Transporter; Branched-Chain Amino Acid Transporter; Urea ABC Transporter Permease; Permease Of ABC Transporter; ABC Transporter Membrane Spanning Protein; Permease Component Of ABC Transporter; Urea Or Short-Chain Amide ABC Transporter; Urea Or Short-Chain Amide ABC Transporter Permease Protein; Amide-Urea Transport System Permease Protein; Branched-Chain Amino Acid Inner-Membrane Translocator; Branched-Chain Amino Acid Transport Permease; Branched Chain Amino Acid ABC Transporter Permease Protein; Amide-Urea Transporter Permease Protein; Transmembrane Component Of ABC Transporter; High-Affinity Branched-Chain Amino Acid Transport System; Urea/Short Chain-Amide ABC Transporter Permease Protein; Urea ABC Transporter Permease Protein; ABC Transporter Related Protein; ABC Transporter Membrane Protein; ABC Transporter ; ABC-Type Urea Transport System Permease Protein II; Urea Transport System Permease Protein; ABC Transporter Inner-Membrane Translocator; ABC-Type Transport System Permease Protein; Integral Membrane Protein; Urea ABC Transporter Inner-Membrane Subunit UrtC; ABC Branched Amino Acid Transporter Permease Component; ABC-Type Branched-Chain Amino Acid Transport System; Branched-Chain Amino Acid Transport System Permease; Permease Protein Of ABC Transporter; Urea Transport System Permease Component Protein; Permease Transporter Transmembrane Protein; Urea ABC Transport Permease Component UrtC

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MQSFHSNSPGTPFRLSVPERQPLFTGRGWAVLAMLTLVVAVGVPVCALMVPEGHPLHLSAYALTLIGKIMCFALAAIALD
LVWGYCGILSLGHGLFFALGGYAMGMYLMRSIGREGVYKSDLPDFMVFLDWKELPWFWHGTEHLWYALLLVVLVPGVLAW
LFGFFAFRSRIKGVYLSIITQAMTYAAMLLFFRNETGFGGNNGFTDFKRIADFAIAAPQTRTALFVLTFLALIAGFVACR
YIVTSKLGRVVTAVRDAEMRVMFSGYNPLGYKLFVWTFSAVLCGVAGALYVPQVGIINPGEMSPGNSIEMAVWVAVGGRG
TLIGPVIGAFLVNGAKTMFTAYFAEYWLFLLGAMFVLVTLYLPDGVIGLWKRLRQRGSRATPAVAAPTEAVSSPAVAGRT
GGEA

Sequences:

>Translated_404_residues
MQSFHSNSPGTPFRLSVPERQPLFTGRGWAVLAMLTLVVAVGVPVCALMVPEGHPLHLSAYALTLIGKIMCFALAAIALD
LVWGYCGILSLGHGLFFALGGYAMGMYLMRSIGREGVYKSDLPDFMVFLDWKELPWFWHGTEHLWYALLLVVLVPGVLAW
LFGFFAFRSRIKGVYLSIITQAMTYAAMLLFFRNETGFGGNNGFTDFKRIADFAIAAPQTRTALFVLTFLALIAGFVACR
YIVTSKLGRVVTAVRDAEMRVMFSGYNPLGYKLFVWTFSAVLCGVAGALYVPQVGIINPGEMSPGNSIEMAVWVAVGGRG
TLIGPVIGAFLVNGAKTMFTAYFAEYWLFLLGAMFVLVTLYLPDGVIGLWKRLRQRGSRATPAVAAPTEAVSSPAVAGRT
GGEA
>Mature_404_residues
MQSFHSNSPGTPFRLSVPERQPLFTGRGWAVLAMLTLVVAVGVPVCALMVPEGHPLHLSAYALTLIGKIMCFALAAIALD
LVWGYCGILSLGHGLFFALGGYAMGMYLMRSIGREGVYKSDLPDFMVFLDWKELPWFWHGTEHLWYALLLVVLVPGVLAW
LFGFFAFRSRIKGVYLSIITQAMTYAAMLLFFRNETGFGGNNGFTDFKRIADFAIAAPQTRTALFVLTFLALIAGFVACR
YIVTSKLGRVVTAVRDAEMRVMFSGYNPLGYKLFVWTFSAVLCGVAGALYVPQVGIINPGEMSPGNSIEMAVWVAVGGRG
TLIGPVIGAFLVNGAKTMFTAYFAEYWLFLLGAMFVLVTLYLPDGVIGLWKRLRQRGSRATPAVAAPTEAVSSPAVAGRT
GGEA

Specific function: Part Of The Binding-Protein-Dependent Transport System For Branched-Chain Amino Acids. Probably Responsible For The Translocation Of The Substrates Across The Membrane. [C]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789865, Length=339, Percent_Identity=22.1238938053097, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 43929; Mature: 43929

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure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HCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA