Definition Ralstonia eutropha JMP134 chromosome 1, complete sequence.
Accession NC_007347
Length 3,806,533

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The map label for this gene is livG [H]

Identifier: 73540692

GI number: 73540692

Start: 1078620

End: 1079468

Strand: Direct

Name: livG [H]

Synonym: Reut_A0989

Alternate gene names: 73540692

Gene position: 1078620-1079468 (Clockwise)

Preceding gene: 73540691

Following gene: 73540693

Centisome position: 28.34

GC content: 64.9

Gene sequence:

>849_bases
ATGAATGCCGCGCTCGAATACGGTCAGGCGGAAAGCGGCAATGCCACGGGCCTTGGCCGCGTAGTGGAGCCGGGCACGAT
CGATGTCTCGCATGGCCCCATCCTTTACCTGGAAGACGTGACGGTGCAGTTCGGCGGCTTCCGCGCGCTCAACAAGCTGA
GCCTGTCGATCGACCACGGCGAACTGCGCTGCGTGATCGGCCCCAATGGCGCCGGCAAGACCACGATGATGGACGTCATC
ACCGGCAAGACAGGCCCGCGCAACGCCAACGTGAGCGGCCGCGTGTTCCTGGGCCAGACCATCGACCTGATCCGCATGAC
CGAGCCGCGCATCGCGCAGGTCGGCATCGGCCGCAAGTTCCAGAAGCCGACGGTGTTCGAGCAGCATGCCGTCTGGGAAA
ACCTCGAACTCGCGATGAAGGCCGACAAGCGCTGGTGGTCGTCGCTGCGTGCCCGGCTGACCGGGGAGGGGCATCGTCGC
ATTGAAGAGACGCTGGCGCTGACGGGGCTGGAGGACGAGGCCTATCGTCCGGCCGGATTGCTGTCGCACGGCCAGAAGCA
GCGGCTGGAGATCGGCATGCTGTTGATGCAGCAGCCGCAGCTGTTGCTGCTGGACGAACCCGTGGCCGGCATGACCGATG
AGGAAACCATGCAACTCGCCGCGCTGCTGAACAGCCTGCGTGGCAGTTGCTCGATGATGGTGGTCGAGCATGACATGGAG
TTCGTCGCGGCGCTGGCCGGCGACGAGGGCAGGGTCACGGTGCTTGCCGAGGGCAGCGTGCTCGCCGAAGGCACGCTCGA
CAGCGTCAAGCGCGATGAACGCGTGATCGAATCCTATTTGGGAAGATAG

Upstream 100 bases:

>100_bases
AGCGTCTGCGCCAACGCGGCAGCCGTGCCACGCCGGCAGTGGCCGCGCCGACCGAGGCCGTATCCAGTCCTGCAGTAGCA
GGACGCACCGGAGGTGAAGC

Downstream 100 bases:

>100_bases
CCATGCTGCAGGTCAATGCACTGAACCAGTTCTACGGCGGCAGCCATATCCTGCGCAACGTCTCGTTCGAGGTGCCGCGC
GGCAAGCTCACCACGCTGCT

Product: ABC transporter related

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein G [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNAALEYGQAESGNATGLGRVVEPGTIDVSHGPILYLEDVTVQFGGFRALNKLSLSIDHGELRCVIGPNGAGKTTMMDVI
TGKTGPRNANVSGRVFLGQTIDLIRMTEPRIAQVGIGRKFQKPTVFEQHAVWENLELAMKADKRWWSSLRARLTGEGHRR
IEETLALTGLEDEAYRPAGLLSHGQKQRLEIGMLLMQQPQLLLLDEPVAGMTDEETMQLAALLNSLRGSCSMMVVEHDME
FVAALAGDEGRVTVLAEGSVLAEGTLDSVKRDERVIESYLGR

Sequences:

>Translated_282_residues
MNAALEYGQAESGNATGLGRVVEPGTIDVSHGPILYLEDVTVQFGGFRALNKLSLSIDHGELRCVIGPNGAGKTTMMDVI
TGKTGPRNANVSGRVFLGQTIDLIRMTEPRIAQVGIGRKFQKPTVFEQHAVWENLELAMKADKRWWSSLRARLTGEGHRR
IEETLALTGLEDEAYRPAGLLSHGQKQRLEIGMLLMQQPQLLLLDEPVAGMTDEETMQLAALLNSLRGSCSMMVVEHDME
FVAALAGDEGRVTVLAEGSVLAEGTLDSVKRDERVIESYLGR
>Mature_282_residues
MNAALEYGQAESGNATGLGRVVEPGTIDVSHGPILYLEDVTVQFGGFRALNKLSLSIDHGELRCVIGPNGAGKTTMMDVI
TGKTGPRNANVSGRVFLGQTIDLIRMTEPRIAQVGIGRKFQKPTVFEQHAVWENLELAMKADKRWWSSLRARLTGEGHRR
IEETLALTGLEDEAYRPAGLLSHGQKQRLEIGMLLMQQPQLLLLDEPVAGMTDEETMQLAALLNSLRGSCSMMVVEHDME
FVAALAGDEGRVTVLAEGSVLAEGTLDSVKRDERVIESYLGR

Specific function: Component of the leucine-specific transport system [H]

COG id: COG4674

COG function: function code R; Uncharacterized ABC-type transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI150417984, Length=258, Percent_Identity=31.3953488372093, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI31657092, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI27881501, Length=235, Percent_Identity=27.2340425531915, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI30795238, Length=235, Percent_Identity=27.2340425531915, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI116734710, Length=220, Percent_Identity=26.8181818181818, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI45446740, Length=231, Percent_Identity=26.4069264069264, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI47078218, Length=231, Percent_Identity=26.4069264069264, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI105990541, Length=225, Percent_Identity=24.8888888888889, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1789864, Length=258, Percent_Identity=33.7209302325581, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790525, Length=258, Percent_Identity=26.3565891472868, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790739, Length=239, Percent_Identity=30.1255230125523, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790544, Length=242, Percent_Identity=28.9256198347107, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082268, Length=257, Percent_Identity=30.7392996108949, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789593, Length=239, Percent_Identity=26.7782426778243, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081791, Length=236, Percent_Identity=27.1186440677966, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790190, Length=255, Percent_Identity=29.0196078431373, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994943, Length=247, Percent_Identity=30.3643724696356, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787792, Length=249, Percent_Identity=26.5060240963855, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788761, Length=254, Percent_Identity=26.3779527559055, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787370, Length=238, Percent_Identity=27.3109243697479, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790467, Length=230, Percent_Identity=28.695652173913, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1786398, Length=225, Percent_Identity=27.5555555555556, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081709, Length=249, Percent_Identity=26.1044176706827, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787029, Length=232, Percent_Identity=25, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081782, Length=241, Percent_Identity=27.8008298755187, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788053, Length=178, Percent_Identity=30.3370786516854, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788225, Length=251, Percent_Identity=25.8964143426295, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787089, Length=235, Percent_Identity=26.3829787234043, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI48995001, Length=233, Percent_Identity=28.3261802575107, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789991, Length=216, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790162, Length=228, Percent_Identity=25, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786253, Length=253, Percent_Identity=24.901185770751, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787164, Length=253, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788897, Length=244, Percent_Identity=25.4098360655738, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786872, Length=245, Percent_Identity=27.3469387755102, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789672, Length=245, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787548, Length=247, Percent_Identity=25.9109311740891, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081834, Length=212, Percent_Identity=25.4716981132075, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788472, Length=253, Percent_Identity=25.296442687747, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786563, Length=215, Percent_Identity=28.8372093023256, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787972, Length=243, Percent_Identity=27.5720164609054, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789586, Length=245, Percent_Identity=26.1224489795918, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789873, Length=213, Percent_Identity=24.8826291079812, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788450, Length=240, Percent_Identity=27.5, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786803, Length=246, Percent_Identity=26.8292682926829, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787105, Length=223, Percent_Identity=29.5964125560538, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87082267, Length=208, Percent_Identity=26.4423076923077, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=241, Percent_Identity=30.2904564315353, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17565586, Length=221, Percent_Identity=30.316742081448, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71983523, Length=247, Percent_Identity=27.9352226720648, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71983516, Length=247, Percent_Identity=27.9352226720648, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71983510, Length=247, Percent_Identity=27.9352226720648, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115533608, Length=213, Percent_Identity=26.7605633802817, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=251, Percent_Identity=26.6932270916335, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI161076682, Length=255, Percent_Identity=28.2352941176471, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076684, Length=255, Percent_Identity=28.2352941176471, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581617, Length=255, Percent_Identity=28.2352941176471, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581615, Length=255, Percent_Identity=28.2352941176471, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666092, Length=252, Percent_Identity=24.2063492063492, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI116007328, Length=222, Percent_Identity=27.9279279279279, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28574150, Length=222, Percent_Identity=27.9279279279279, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920532, Length=217, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24580930, Length=217, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85816269, Length=170, Percent_Identity=28.8235294117647, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24580553, Length=170, Percent_Identity=28.8235294117647, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI85724864, Length=170, Percent_Identity=28.8235294117647, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24580555, Length=170, Percent_Identity=28.8235294117647, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221512771, Length=241, Percent_Identity=26.1410788381743, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24643674, Length=229, Percent_Identity=24.8908296943231, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 30784; Mature: 30784

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNAALEYGQAESGNATGLGRVVEPGTIDVSHGPILYLEDVTVQFGGFRALNKLSLSIDHG
CCCCCCCCCCCCCCCCCCCEEECCCEEEECCCCEEEEEEEEEEECCEEEEEEEEEEEECC
ELRCVIGPNGAGKTTMMDVITGKTGPRNANVSGRVFLGQTIDLIRMTEPRIAQVGIGRKF
EEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCEEEEECCCCCEEEECCCCCC
QKPTVFEQHAVWENLELAMKADKRWWSSLRARLTGEGHRRIEETLALTGLEDEAYRPAGL
CCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHH
LSHGQKQRLEIGMLLMQQPQLLLLDEPVAGMTDEETMQLAALLNSLRGSCSMMVVEHDME
HHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCHH
FVAALAGDEGRVTVLAEGSVLAEGTLDSVKRDERVIESYLGR
HHHHHCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAALEYGQAESGNATGLGRVVEPGTIDVSHGPILYLEDVTVQFGGFRALNKLSLSIDHG
CCCCCCCCCCCCCCCCCCCEEECCCEEEECCCCEEEEEEEEEEECCEEEEEEEEEEEECC
ELRCVIGPNGAGKTTMMDVITGKTGPRNANVSGRVFLGQTIDLIRMTEPRIAQVGIGRKF
EEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCEEEEECCCCCEEEECCCCCC
QKPTVFEQHAVWENLELAMKADKRWWSSLRARLTGEGHRRIEETLALTGLEDEAYRPAGL
CCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHH
LSHGQKQRLEIGMLLMQQPQLLLLDEPVAGMTDEETMQLAALLNSLRGSCSMMVVEHDME
HHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCHH
FVAALAGDEGRVTVLAEGSVLAEGTLDSVKRDERVIESYLGR
HHHHHCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]