Click here to switch to the map view.

The map label for this gene is nuoC

Identifier: 73540666

GI number: 73540666

Start: 1050210

End: 1050809

Strand: Direct

Name: nuoC

Synonym: Reut_A0963

Alternate gene names: 73540666

Gene position: 1050210-1050809 (Clockwise)

Preceding gene: 73540665

Following gene: 73540667

Centisome position: 27.59

GC content: 61.83

Gene sequence:

>600_bases
ATGGCGAAGCTTGAGACCCTGAAGGCCGCGCTCGAGAAAGTTCTCGGCAAGCGCGTGCAGAAACTGATCGAGGCGACCGG
CGAACTGACGCTGATCGTCAAGGCAGATGACTACCTCGAAGTTGCCCGCACGCTGCGCGACGATCCGTCGCTGCGTTTCG
AGCAGCTGATCGACCTGTGCGGCGTCGATTATTCCGACTTCGGCGATGGCGCCTGGGATGGTCTGCGTTTTGCCGCGGTA
TCGCACCTGTTGTCCGTGACTCACAACTGGCGTCTGCGTCTGCGTGTGTTTGCGCCGGACGACGACTTCCCGGTCGTGCC
GTCGCTGATCGACGTGTGGAACTCGGTGAACTGGTTCGAGCGCGAAGCGTTCGACTTCTACGGCATCGTCTTCGAAGGCC
ATCCGGACCTGCGCCGCCTGCTGACCGACTACGGTTTTGTCGGCCACCCGTTCCGCAAGGACTTCCCGGTATCGGGCTAC
GTGGAAATGCGCTACGACCCCGAGCAGAAACGGGTCATCTACCAGCCGGTCACGATCGAACCTCGCGAAATCACGCCGCG
CGTGATCCGCGAGGAAAACTACGGCGGCACGCAGCACTGA

Upstream 100 bases:

>100_bases
GTGCCGGGCTGCCCGCCCACGGCTGAAGCGCTGATCTATGGCGTGATCCAGCTGCAGAACAAGATCAAGCGCACCAACAC
CATCGCGCGCAAGGGCTGAC

Downstream 100 bases:

>100_bases
TTAGGCGCCATGGCAGACATCAAGAATTACACCCTGAACTTCGGACCGCAGCACCCGGCCGCGCACGGCGTGCTGCGCCT
CGTGCTGGAGCTGGACGGCG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MAKLETLKAALEKVLGKRVQKLIEATGELTLIVKADDYLEVARTLRDDPSLRFEQLIDLCGVDYSDFGDGAWDGLRFAAV
SHLLSVTHNWRLRLRVFAPDDDFPVVPSLIDVWNSVNWFEREAFDFYGIVFEGHPDLRRLLTDYGFVGHPFRKDFPVSGY
VEMRYDPEQKRVIYQPVTIEPREITPRVIREENYGGTQH

Sequences:

>Translated_199_residues
MAKLETLKAALEKVLGKRVQKLIEATGELTLIVKADDYLEVARTLRDDPSLRFEQLIDLCGVDYSDFGDGAWDGLRFAAV
SHLLSVTHNWRLRLRVFAPDDDFPVVPSLIDVWNSVNWFEREAFDFYGIVFEGHPDLRRLLTDYGFVGHPFRKDFPVSGY
VEMRYDPEQKRVIYQPVTIEPREITPRVIREENYGGTQH
>Mature_198_residues
AKLETLKAALEKVLGKRVQKLIEATGELTLIVKADDYLEVARTLRDDPSLRFEQLIDLCGVDYSDFGDGAWDGLRFAAVS
HLLSVTHNWRLRLRVFAPDDDFPVVPSLIDVWNSVNWFEREAFDFYGIVFEGHPDLRRLLTDYGFVGHPFRKDFPVSGYV
EMRYDPEQKRVIYQPVTIEPREITPRVIREENYGGTQH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=178, Percent_Identity=41.0112359550562, Blast_Score=139, Evalue=1e-33,
Organism=Escherichia coli, GI145693162, Length=136, Percent_Identity=35.2941176470588, Blast_Score=78, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563621, Length=175, Percent_Identity=41.1428571428571, Blast_Score=130, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71990788, Length=165, Percent_Identity=43.030303030303, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24656494, Length=170, Percent_Identity=41.1764705882353, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_CUPPJ (Q473U1)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_295186.1
- ProteinModelPortal:   Q473U1
- SMR:   Q473U1
- GeneID:   3609359
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A0963
- NMPDR:   fig|264198.3.peg.1363
- HOGENOM:   HBG727675
- OMA:   VFAPDDD
- ProtClustDB:   PRK06074
- BioCyc:   REUT264198:REUT_A0963-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23061; Mature: 22930

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLETLKAALEKVLGKRVQKLIEATGELTLIVKADDYLEVARTLRDDPSLRFEQLIDLC
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHH
GVDYSDFGDGAWDGLRFAAVSHLLSVTHNWRLRLRVFAPDDDFPVVPSLIDVWNSVNWFE
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCHHH
REAFDFYGIVFEGHPDLRRLLTDYGFVGHPFRKDFPVSGYVEMRYDPEQKRVIYQPVTIE
HHHHHEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
PREITPRVIREENYGGTQH
CHHCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
AKLETLKAALEKVLGKRVQKLIEATGELTLIVKADDYLEVARTLRDDPSLRFEQLIDLC
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHH
GVDYSDFGDGAWDGLRFAAVSHLLSVTHNWRLRLRVFAPDDDFPVVPSLIDVWNSVNWFE
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCHHH
REAFDFYGIVFEGHPDLRRLLTDYGFVGHPFRKDFPVSGYVEMRYDPEQKRVIYQPVTIE
HHHHHEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
PREITPRVIREENYGGTQH
CHHCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA