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The map label for this gene is trpS [H]

Identifier: 73540207

GI number: 73540207

Start: 545117

End: 546217

Strand: Direct

Name: trpS [H]

Synonym: Reut_A0501

Alternate gene names: 73540207

Gene position: 545117-546217 (Clockwise)

Preceding gene: 73540206

Following gene: 73540223

Centisome position: 14.32

GC content: 63.31

Gene sequence:

>1101_bases
ATGCATCCGACAGATCGGCCGCCTGAAGGCCGGACCGCTTACATCCCCAAATTTCCGCGAATTTCCGCAATGACAGCCAA
CACGCAAACCAACAAGCGACCCGTCATCCTGACCGGCGATCGTCCCACCGGCCCGCTGCACCTCGGCCACTATGTCGGCT
CGCTCAAGACGCGCGTGCAGCTGCAGGATACGCATGAGCAGTACCTGCTGCTGGCCGATACGCAGGCCATGACCGACAAC
GCGCACGATCCCGACAAGGTGCGCCGCAATGTGCTGGAAGTGGCGCTGGACTACCTGGCCGTCGGCATCGATCCGACGAA
GACCACCATCACGGTGCAATCGTACCTGCCGGCGCTCGCCGAGCTGACGCTGATGTACCTGAACTTCGTCACGGTCTCGC
GCCTGGAGCGCAACCCGACGATCAAGGAAGAAATCCAGGCGCGCGGTTTCGGCCGCGATATCCCGGCCGGCTTCATGTGC
TATCCGGCTGCGCAGGCTGCGGACATCACCGCGTTCAAGGCCGACATCGTGCCCGTCGGTGAAGACCAGGCGCCGCTGAT
CGAGCAGACCAACGAGATCGTTCGCCGCATCAACCATCAGGTTGGCCGCGACGTGCTGAAGGAATGCCAGGCGCTGATCC
CGAAGTTCGGCCGCCTGCCGGGCGTCGACGGCAAGGCCAAGATGAGCAAGTCGCAGGGCAACGCCATTGCGCTGGGCGCG
AGCCCCGAGCAGGTCAAGGCAGCCGTGCATAGCATGTACACCGACCCGGATCACCTGAAGGTATCCGACCCGGGCAAGGT
CGAAGGCAATATGGTGTTCACTTACCTGGATGCCTTCGACCCGAACACCGAAGAAGTCGAAGAACTCAAGGCGCACTATC
GCCGCGGTGGCCTTGGCGACATGGTGCTCAAGCGCCGCGTCGAAGGCGTTCTGAACGAACTGCTGGGCCCGATCCGCGAG
CGCCGTGAACAACTCGCCAAGGATCCGGACTATGTGTTCGACCTGCTGCGCGAGGGGACGAACCGGGCCAAGGCCATCAC
CCAGCAGACGCTGGACGAGGTCCGCGAGGCGCTGGGGATGTTCTCTTTTGGCAGCCGCTGA

Upstream 100 bases:

>100_bases
GACCAGATCGATTTCGAGGCCATCGGCTTCGACCTTGGCCGCCGCGCTGAAGAGGTGCCGGTCGGCGAGTACGTCGAGCT
GGCGCGCCGCTTGGGCGGCG

Downstream 100 bases:

>100_bases
ATCTTTGATCAGGCCGGCAACGGCCAACAAAAAACGCGCGGAACCGATCCGCGCGTTTTTTTATGCCTTGGAATCAGCCA
CTTCGGCAGCCACTTCAGCT

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MHPTDRPPEGRTAYIPKFPRISAMTANTQTNKRPVILTGDRPTGPLHLGHYVGSLKTRVQLQDTHEQYLLLADTQAMTDN
AHDPDKVRRNVLEVALDYLAVGIDPTKTTITVQSYLPALAELTLMYLNFVTVSRLERNPTIKEEIQARGFGRDIPAGFMC
YPAAQAADITAFKADIVPVGEDQAPLIEQTNEIVRRINHQVGRDVLKECQALIPKFGRLPGVDGKAKMSKSQGNAIALGA
SPEQVKAAVHSMYTDPDHLKVSDPGKVEGNMVFTYLDAFDPNTEEVEELKAHYRRGGLGDMVLKRRVEGVLNELLGPIRE
RREQLAKDPDYVFDLLREGTNRAKAITQQTLDEVREALGMFSFGSR

Sequences:

>Translated_366_residues
MHPTDRPPEGRTAYIPKFPRISAMTANTQTNKRPVILTGDRPTGPLHLGHYVGSLKTRVQLQDTHEQYLLLADTQAMTDN
AHDPDKVRRNVLEVALDYLAVGIDPTKTTITVQSYLPALAELTLMYLNFVTVSRLERNPTIKEEIQARGFGRDIPAGFMC
YPAAQAADITAFKADIVPVGEDQAPLIEQTNEIVRRINHQVGRDVLKECQALIPKFGRLPGVDGKAKMSKSQGNAIALGA
SPEQVKAAVHSMYTDPDHLKVSDPGKVEGNMVFTYLDAFDPNTEEVEELKAHYRRGGLGDMVLKRRVEGVLNELLGPIRE
RREQLAKDPDYVFDLLREGTNRAKAITQQTLDEVREALGMFSFGSR
>Mature_366_residues
MHPTDRPPEGRTAYIPKFPRISAMTANTQTNKRPVILTGDRPTGPLHLGHYVGSLKTRVQLQDTHEQYLLLADTQAMTDN
AHDPDKVRRNVLEVALDYLAVGIDPTKTTITVQSYLPALAELTLMYLNFVTVSRLERNPTIKEEIQARGFGRDIPAGFMC
YPAAQAADITAFKADIVPVGEDQAPLIEQTNEIVRRINHQVGRDVLKECQALIPKFGRLPGVDGKAKMSKSQGNAIALGA
SPEQVKAAVHSMYTDPDHLKVSDPGKVEGNMVFTYLDAFDPNTEEVEELKAHYRRGGLGDMVLKRRVEGVLNELLGPIRE
RREQLAKDPDYVFDLLREGTNRAKAITQQTLDEVREALGMFSFGSR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=363, Percent_Identity=27.2727272727273, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI41352700, Length=198, Percent_Identity=30.3030303030303, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1789786, Length=336, Percent_Identity=30.6547619047619, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71982793, Length=380, Percent_Identity=26.8421052631579, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71982800, Length=356, Percent_Identity=27.247191011236, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320474, Length=356, Percent_Identity=24.438202247191, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24666151, Length=334, Percent_Identity=31.7365269461078, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 40711; Mature: 40711

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPTDRPPEGRTAYIPKFPRISAMTANTQTNKRPVILTGDRPTGPLHLGHYVGSLKTRVQ
CCCCCCCCCCCEEECCCCCCCEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHEEE
LQDTHEQYLLLADTQAMTDNAHDPDKVRRNVLEVALDYLAVGIDPTKTTITVQSYLPALA
EECCCCCEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
ELTLMYLNFVTVSRLERNPTIKEEIQARGFGRDIPAGFMCYPAAQAADITAFKADIVPVG
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEECCCCCCCHHHEEEECCEECC
EDQAPLIEQTNEIVRRINHQVGRDVLKECQALIPKFGRLPGVDGKAKMSKSQGNAIALGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEECC
SPEQVKAAVHSMYTDPDHLKVSDPGKVEGNMVFTYLDAFDPNTEEVEELKAHYRRGGLGD
CHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHH
MVLKRRVEGVLNELLGPIRERREQLAKDPDYVFDLLREGTNRAKAITQQTLDEVREALGM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FSFGSR
HCCCCC
>Mature Secondary Structure
MHPTDRPPEGRTAYIPKFPRISAMTANTQTNKRPVILTGDRPTGPLHLGHYVGSLKTRVQ
CCCCCCCCCCCEEECCCCCCCEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHEEE
LQDTHEQYLLLADTQAMTDNAHDPDKVRRNVLEVALDYLAVGIDPTKTTITVQSYLPALA
EECCCCCEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
ELTLMYLNFVTVSRLERNPTIKEEIQARGFGRDIPAGFMCYPAAQAADITAFKADIVPVG
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEECCCCCCCHHHEEEECCEECC
EDQAPLIEQTNEIVRRINHQVGRDVLKECQALIPKFGRLPGVDGKAKMSKSQGNAIALGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEECC
SPEQVKAAVHSMYTDPDHLKVSDPGKVEGNMVFTYLDAFDPNTEEVEELKAHYRRGGLGD
CHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHH
MVLKRRVEGVLNELLGPIRERREQLAKDPDYVFDLLREGTNRAKAITQQTLDEVREALGM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FSFGSR
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA