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The map label for this gene is ycgM [H]

Identifier: 73539623

GI number: 73539623

Start: 2626758

End: 2627456

Strand: Direct

Name: ycgM [H]

Synonym: Reut_B5803

Alternate gene names: 73539623

Gene position: 2626758-2627456 (Clockwise)

Preceding gene: 73539622

Following gene: 73539624

Centisome position: 96.35

GC content: 66.38

Gene sequence:

>699_bases
ATGTCCTACATCTTCACGCCGCCTGCAACTGTCTCCATCCCTGTCGCGGGCAGCGACGACCAGTTCGCCGTGCGCCGCGT
CTACTGCGTCGGCCGCAACTACGCCGCCCATGCGCGCGAGATGGGCTTTGATCCCGACCGCGAGCCCCCGTTCTTCTTCT
GCAAGCCCGCCGACGCCATCATGCCGGTGCAGGACGGCCAGGTGCTGGAACTGCCATATCCCGCGCAGACCACCAACTAT
CACTACGAAGCCGAACTCGTGGCCGTGATCGGCAAGGCCGGTTCCGACATCCCCGTCGACCAGGCGCTCGAGCATGTTTG
GGGCTACGCCGTGGGCCTGGACATGACCCGCCGCGACCTGCAGATGAAGATGCGCGAGATGGGCCGCCCGTGGGAGATCG
GCAAGGCCTTCGACGCCTCGGCACCGGTCGCGCCGATCCATCGCGCTGCCGATATCGGCCACCCGCAAGAGGCTGCGCTC
TGGCTGACCGTCAACGGCGAAGACAAGCAGCGCAGCAATATCACGCACCTGATCTGGTCGGTGGCCGAGACGGTGGCGTA
CCTGTCGCAGTTCTTCCGGCTGGAGCCGGGCGACGTGATTTTTACCGGCACGCCGGAAGGCGTGGGTGCGGTAAAGGCCG
GCGAGACGATGGTGACGGGCGTGGACGGGCTCGGCGAACTGACCGTGCGCGTGGTCTGA

Upstream 100 bases:

>100_bases
ATCCGATTTCCTTTCGATAAAAGCCAACAGGCCGCGCCGCCACAGGCGCTGCCTCGGACCCGCTCAACCTGCGTTTGCCA
AATCTTTAACCGAGACTGTC

Downstream 100 bases:

>100_bases
CGGAAATTCACGGGAGTCGACATGCAGCTCTACAGTTTTTTCAATAGTTCCACGTCGTACCGCGTGCGCATCGCCCTCGC
GCTCAAGGGCCTGTCGTACG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSYIFTPPATVSIPVAGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAIMPVQDGQVLELPYPAQTTNY
HYEAELVAVIGKAGSDIPVDQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDASAPVAPIHRAADIGHPQEAAL
WLTVNGEDKQRSNITHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGETMVTGVDGLGELTVRVV

Sequences:

>Translated_232_residues
MSYIFTPPATVSIPVAGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAIMPVQDGQVLELPYPAQTTNY
HYEAELVAVIGKAGSDIPVDQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDASAPVAPIHRAADIGHPQEAAL
WLTVNGEDKQRSNITHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGETMVTGVDGLGELTVRVV
>Mature_231_residues
SYIFTPPATVSIPVAGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAIMPVQDGQVLELPYPAQTTNYH
YEAELVAVIGKAGSDIPVDQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDASAPVAPIHRAADIGHPQEAALW
LTVNGEDKQRSNITHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGETMVTGVDGLGELTVRVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=41.0628019323672, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=41.5, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=40.6862745098039, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI156231349, Length=215, Percent_Identity=35.8139534883721, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI40786394, Length=215, Percent_Identity=35.3488372093023, Blast_Score=122, Evalue=2e-28,
Organism=Escherichia coli, GI1787428, Length=212, Percent_Identity=39.1509433962264, Blast_Score=153, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17557057, Length=196, Percent_Identity=36.734693877551, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6324161, Length=221, Percent_Identity=28.5067873303167, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28571789, Length=212, Percent_Identity=36.7924528301887, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI28572127, Length=216, Percent_Identity=33.7962962962963, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24663695, Length=221, Percent_Identity=28.5067873303167, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25437; Mature: 25306

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYIFTPPATVSIPVAGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAI
CCEEECCCCEEEEEECCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
MPVQDGQVLELPYPAQTTNYHYEAELVAVIGKAGSDIPVDQALEHVWGYAVGLDMTRRDL
EECCCCCEEECCCCCCCCCEEEHEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHH
QMKMREMGRPWEIGKAFDASAPVAPIHRAADIGHPQEAALWLTVNGEDKQRSNITHLIWS
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
VAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGETMVTGVDGLGELTVRVV
HHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCCEEEECCCCCCCEEEEEC
>Mature Secondary Structure 
SYIFTPPATVSIPVAGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAI
CEEECCCCEEEEEECCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
MPVQDGQVLELPYPAQTTNYHYEAELVAVIGKAGSDIPVDQALEHVWGYAVGLDMTRRDL
EECCCCCEEECCCCCCCCCEEEHEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHH
QMKMREMGRPWEIGKAFDASAPVAPIHRAADIGHPQEAALWLTVNGEDKQRSNITHLIWS
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
VAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGETMVTGVDGLGELTVRVV
HHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCCEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]