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The map label for this gene is 73539622

Identifier: 73539622

GI number: 73539622

Start: 2625564

End: 2626658

Strand: Direct

Name: 73539622

Synonym: Reut_B5802

Alternate gene names: NA

Gene position: 2625564-2626658 (Clockwise)

Preceding gene: 73539621

Following gene: 73539623

Centisome position: 96.31

GC content: 64.93

Gene sequence:

>1095_bases
ATGCGGCCGATGCGCGCCGCCATGTACAACAATCATTACGGAGATACTATGGACGCACGCCAATCCGGCGCCGATCGTGC
TGCTTACTACGCCGATATCGGCCGAAGCCACATGAGCGCCCTTTGGGAATCGCTGCACACGCTGGTGCCGCGGCAGCCCC
AGCCGAAGATTCTGCCGGCCATCTGGAAGTACAGGCAGGTCCGTCCGCTGGTGATGCAGGCTGGCAATCTCATCAGTGCC
CAGGAAGCCGTGCGCCGCGTGCTGGTGCTGGAGAATCCGGGCCTGCCTGGCAAATCGAGCATCACCGGCTCGCTCTACGC
CGGGCTGCAACTGATCTTGCCGGGCGAGGTCGCGCCGAGTCATCGCCATACGCAGTCGGCGCTGCGCTTTATCGTGGAGG
GGCAAGGTGCCTGGACCGCCGTGAATGGCGAGCGTACCACCATGCGCCCCGGCGACTTCATCATTACGCCCTCGTGGACG
TGGCACGACCACGGCAATCCGGCCGTCGAGAACGGCGGTGAGCCGGTGGTCTGGCTCGATGGACTCGATATTCCGCTGGT
GCAATTCTTCGACGGCGGCTTTGCCGAGAACTACCCCGAGGCGCAGCAGCCGGTCACGCGGCCCGAGGGCGACAGCTTTG
CCCGCTTTGGTCACAACATGGTGCCGGTGCGCCACAATGTTTCCGACCCGACCTCGCCGATTTTCAGCTACCCGTACGAC
CGCTCCCGCGAGGCGCTCGACCAGCTCTACCGCAACGGCGAACTCGATGCCTGGGACGGCGTGAAGCTACGCTACGTCAA
CCCTGCCACGGGCGGCTGGCCCATGCCGACCATCGCGACCTTCATGCAATACCTGCCGGCGGGCTTCCAGGGCCGCACGT
ACCGCAGCACGGACGCAACCGTCTACAGCGTGGTCGAGGGGCGCGGCACGGTACGTATTGGCGACGAACAATTCCAGTTC
GAACCGCGCGATACCTTCGTGGTTCCCTCTTGGGCTCCGGTGCAACTCGCCGCGCTGGACGAAACCGTGCTGTTCAGCTA
CTCCGACCGCCCCGTGCTGTCCGCGCTCAACCTGCTGCGCGAATCGCGCACCTGA

Upstream 100 bases:

>100_bases
TGTTCTCGCTTGGCTTCGACATGCTGGAGCGGGCGCTGCTGCCGTGGCGCGTGGTCGCTCGTGGGCATAGGCGAGGGCGG
CCCTGAACGCATGGGTCCCA

Downstream 100 bases:

>100_bases
TCCGATTTCCTTTCGATAAAAGCCAACAGGCCGCGCCGCCACAGGCGCTGCCTCGGACCCGCTCAACCTGCGTTTGCCAA
ATCTTTAACCGAGACTGTCA

Product: gentisate 1,2-dioxygenase

Products: maleylpyruvate

Alternate protein names: Cupin 2 Domain-Containing Protein; Cupin 2 Conserved Barrel Domain Protein; Cupin 2 Barrel; Cupin 2 Conserved Barrel Domain-Containing Protein; 1 2-Dioxygenase; Gentisate 1 2-Dioxygenase Oxidoreductase Protein; Cupin 2 Protein; 1-Hydroxy-2-Naphthoate Dioxygenase; Gentisate 1 2-Dioxygenase Oxidoreductase; Dioxygenase Oxidoreductase Protein; Dioxygenase

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MRPMRAAMYNNHYGDTMDARQSGADRAAYYADIGRSHMSALWESLHTLVPRQPQPKILPAIWKYRQVRPLVMQAGNLISA
QEAVRRVLVLENPGLPGKSSITGSLYAGLQLILPGEVAPSHRHTQSALRFIVEGQGAWTAVNGERTTMRPGDFIITPSWT
WHDHGNPAVENGGEPVVWLDGLDIPLVQFFDGGFAENYPEAQQPVTRPEGDSFARFGHNMVPVRHNVSDPTSPIFSYPYD
RSREALDQLYRNGELDAWDGVKLRYVNPATGGWPMPTIATFMQYLPAGFQGRTYRSTDATVYSVVEGRGTVRIGDEQFQF
EPRDTFVVPSWAPVQLAALDETVLFSYSDRPVLSALNLLRESRT

Sequences:

>Translated_364_residues
MRPMRAAMYNNHYGDTMDARQSGADRAAYYADIGRSHMSALWESLHTLVPRQPQPKILPAIWKYRQVRPLVMQAGNLISA
QEAVRRVLVLENPGLPGKSSITGSLYAGLQLILPGEVAPSHRHTQSALRFIVEGQGAWTAVNGERTTMRPGDFIITPSWT
WHDHGNPAVENGGEPVVWLDGLDIPLVQFFDGGFAENYPEAQQPVTRPEGDSFARFGHNMVPVRHNVSDPTSPIFSYPYD
RSREALDQLYRNGELDAWDGVKLRYVNPATGGWPMPTIATFMQYLPAGFQGRTYRSTDATVYSVVEGRGTVRIGDEQFQF
EPRDTFVVPSWAPVQLAALDETVLFSYSDRPVLSALNLLRESRT
>Mature_364_residues
MRPMRAAMYNNHYGDTMDARQSGADRAAYYADIGRSHMSALWESLHTLVPRQPQPKILPAIWKYRQVRPLVMQAGNLISA
QEAVRRVLVLENPGLPGKSSITGSLYAGLQLILPGEVAPSHRHTQSALRFIVEGQGAWTAVNGERTTMRPGDFIITPSWT
WHDHGNPAVENGGEPVVWLDGLDIPLVQFFDGGFAENYPEAQQPVTRPEGDSFARFGHNMVPVRHNVSDPTSPIFSYPYD
RSREALDQLYRNGELDAWDGVKLRYVNPATGGWPMPTIATFMQYLPAGFQGRTYRSTDATVYSVVEGRGTVRIGDEQFQF
EPRDTFVVPSWAPVQLAALDETVLFSYSDRPVLSALNLLRESRT

Specific function: Unknown

COG id: COG3435

COG function: function code Q; Gentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.13.11.4

Molecular weight: Translated: 40689; Mature: 40689

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPMRAAMYNNHYGDTMDARQSGADRAAYYADIGRSHMSALWESLHTLVPRQPQPKILPA
CCCHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IWKYRQVRPLVMQAGNLISAQEAVRRVLVLENPGLPGKSSITGSLYAGLQLILPGEVAPS
HHHHHHHCHHHHHCCCCCHHHHHHHEEEEEECCCCCCCCCCCHHHHCCEEEEECCCCCCC
HRHTQSALRFIVEGQGAWTAVNGERTTMRPGDFIITPSWTWHDHGNPAVENGGEPVVWLD
HHHHHHHHHEEEECCCCEEEECCCCEEECCCCEEECCCEEECCCCCCHHHCCCCEEEEEC
GLDIPLVQFFDGGFAENYPEAQQPVTRPEGDSFARFGHNMVPVRHNVSDPTSPIFSYPYD
CCCCHHHHHHCCCCCCCCCCHHCCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCC
RSREALDQLYRNGELDAWDGVKLRYVNPATGGWPMPTIATFMQYLPAGFQGRTYRSTDAT
CCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCE
VYSVVEGRGTVRIGDEQFQFEPRDTFVVPSWAPVQLAALDETVLFSYSDRPVLSALNLLR
EEEEECCCCEEEECCHHEEECCCCCEEECCCCCEEEEECCCEEEEECCCCHHHHHHHHHH
ESRT
HCCC
>Mature Secondary Structure
MRPMRAAMYNNHYGDTMDARQSGADRAAYYADIGRSHMSALWESLHTLVPRQPQPKILPA
CCCHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IWKYRQVRPLVMQAGNLISAQEAVRRVLVLENPGLPGKSSITGSLYAGLQLILPGEVAPS
HHHHHHHCHHHHHCCCCCHHHHHHHEEEEEECCCCCCCCCCCHHHHCCEEEEECCCCCCC
HRHTQSALRFIVEGQGAWTAVNGERTTMRPGDFIITPSWTWHDHGNPAVENGGEPVVWLD
HHHHHHHHHEEEECCCCEEEECCCCEEECCCCEEECCCEEECCCCCCHHHCCCCEEEEEC
GLDIPLVQFFDGGFAENYPEAQQPVTRPEGDSFARFGHNMVPVRHNVSDPTSPIFSYPYD
CCCCHHHHHHCCCCCCCCCCHHCCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCC
RSREALDQLYRNGELDAWDGVKLRYVNPATGGWPMPTIATFMQYLPAGFQGRTYRSTDAT
CCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCE
VYSVVEGRGTVRIGDEQFQFEPRDTFVVPSWAPVQLAALDETVLFSYSDRPVLSALNLLR
EEEEECCCCEEEECCHHEEECCCCCEEECCCCCEEEEECCCEEEEECCCCHHHHHHHHHH
ESRT
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2,5-dihydroxybenzoate; O2

Specific reaction: 2,5-dihydroxybenzoate + O2 = maleylpyruvate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA