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The map label for this gene is glpD2 [H]

Identifier: 71907550

GI number: 71907550

Start: 2065308

End: 2066882

Strand: Reverse

Name: glpD2 [H]

Synonym: Daro_1921

Alternate gene names: 71907550

Gene position: 2066882-2065308 (Counterclockwise)

Preceding gene: 71907551

Following gene: 71907549

Centisome position: 45.92

GC content: 65.71

Gene sequence:

>1575_bases
ATGATCAACGCACCGCTCAAGCGCGAAGACGGCCTCGCCAAGCTGCGCGACACTGCCCCTTGGGATGTACTGATCATCGG
CGGTGGCGCCAGCGGCCTGGGCGCAGCCGTCGACGCCGCGGCACGCGGTTACCGCACCCTGCTCATCGAGGCCCGCGACT
TCGCGTCCGGAACCTCATCGTGCAGCACCAAGCTGATTCACGGCGGCGTTCGTTACCTGCGCCAGGGCGACATCGGGCTG
GTCCGCAATGCCCTGCACGAACGCTCGCACCTGCTTCGCAATGCCGCCCATCTGGTGCATCCGCTGGCTTTCATCATCCC
AGCCTGGCGAAACATCGACCGCGTTTTTTACGGCGCCGGCCTGAAGCTTTATGACCTGCTGGCCGGCCGGCAGGGGCTGG
CTGCCTCGCGCAGCCTGAACCGCCAGGACGTGATCGACGCCCTGCCCGGCCTGCGGCGCGCCAGCTTATGCGGCGGTATT
CGCTACTGGGACGGCCAGTTCGATGATGCGCGGCTGGCCATCACGTTGATGCGCACGGCCACTGATCTCGGCGCAAGCTG
CCTCAACTACCTGCCGGTCACCCGGTTGATCAAGACCGGCGGCCGCGTTGCCGGTGCCGTGCTGTGTGACGCGGAAAGCG
GCGAGGAATTCGAAGTCCGCGCCCGTGCCGTGATCAACGCCACCGGAGTGCATGCCGACAGCGTGCGGCGTTTCGATGAC
AGCGCTGCCGTGCCGCTGCTGACCCCAAGCCAGGGCATCCATCTCGTCGTCGATGCCGATTTCCTGCCCGGCCAGCAGGC
AATTCTGGTCCCAAAAACCGAAGACGGCCGCGTCATGTTCGCCATTCCCTGGCAAGGCAAGGTACTGCTTGGCACCACCG
ATACGCCGCGCCCCGAACTAAGCCAGCTCGACGACCCGCAACCGCTGGACGAGGAGATCGACTTCCTGCTGCGTACCGCC
GCCAGCGTCCTCAGCCGCCCACCCACGCGATCCGATATCCGCAGTGCCTTTGCCGGCCTGCGCCCGCTGATCCACCCGGA
CAACAAGGATGGCAAGAGCACCGCCGCCCTGTCGCGCGAACACGCCGTGTTGGTCAGCACCAGCGGACTGATCACCGTCG
CTGGCGGCAAGTGGACGACCTACCGGCTGATGGCCGAGCAGGTGATCGACCGCACCATCGAGGTCGCCGGCCTGCCCGCC
GTGCCATGCCCGACCCGAACACTGAAACTGCACGCTTGCCCGGCCCAGCCAGGCAACGATGTTTATGGCACCGAGGCACC
GCTGCTCGCCACGCTGCCTGGCCACGACCAGCCGCTCCACCCAGAACTGCCTTACAACGCAGCGATGGTGCGCTTCGCCA
TCCGCTACGAAATGGCTCGGACGATTGAAGACGTGCTGGCCCGCCGGACACGTGCCCTGTTTCACGATGCGGCGGCAGCC
GAAAAAATGATCGACCGCATCGCCGGGATATTCGCCGAGGAACTCCAGTTGACCGAAGAACGTTTGGCCAGCTTGATCGA
AGCCGCCCATGAAAGTGCACGGCGTTTCATGGCGGCGCAGAACTCCGGCGCCTGA

Upstream 100 bases:

>100_bases
ACCGGCGCTTTGAGCCGTCCATGGCCGAGGACCGGCGCAGTGCGCTGTTCGCCGACTGGCACCGCGCCGTCGAACGCAGC
CTGCATTGGGCAAACGCGAC

Downstream 100 bases:

>100_bases
ATAGCGGCGCGCTCAGCGCGGAACGCAATGCATTCGTGCCAGCCCAACCGACGCAAAGCGCCAGAGGTGGCCGAACGAGG
CGATCACAAGCGCCTTGGCG

Product: fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal:FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MINAPLKREDGLAKLRDTAPWDVLIIGGGASGLGAAVDAAARGYRTLLIEARDFASGTSSCSTKLIHGGVRYLRQGDIGL
VRNALHERSHLLRNAAHLVHPLAFIIPAWRNIDRVFYGAGLKLYDLLAGRQGLAASRSLNRQDVIDALPGLRRASLCGGI
RYWDGQFDDARLAITLMRTATDLGASCLNYLPVTRLIKTGGRVAGAVLCDAESGEEFEVRARAVINATGVHADSVRRFDD
SAAVPLLTPSQGIHLVVDADFLPGQQAILVPKTEDGRVMFAIPWQGKVLLGTTDTPRPELSQLDDPQPLDEEIDFLLRTA
ASVLSRPPTRSDIRSAFAGLRPLIHPDNKDGKSTAALSREHAVLVSTSGLITVAGGKWTTYRLMAEQVIDRTIEVAGLPA
VPCPTRTLKLHACPAQPGNDVYGTEAPLLATLPGHDQPLHPELPYNAAMVRFAIRYEMARTIEDVLARRTRALFHDAAAA
EKMIDRIAGIFAEELQLTEERLASLIEAAHESARRFMAAQNSGA

Sequences:

>Translated_524_residues
MINAPLKREDGLAKLRDTAPWDVLIIGGGASGLGAAVDAAARGYRTLLIEARDFASGTSSCSTKLIHGGVRYLRQGDIGL
VRNALHERSHLLRNAAHLVHPLAFIIPAWRNIDRVFYGAGLKLYDLLAGRQGLAASRSLNRQDVIDALPGLRRASLCGGI
RYWDGQFDDARLAITLMRTATDLGASCLNYLPVTRLIKTGGRVAGAVLCDAESGEEFEVRARAVINATGVHADSVRRFDD
SAAVPLLTPSQGIHLVVDADFLPGQQAILVPKTEDGRVMFAIPWQGKVLLGTTDTPRPELSQLDDPQPLDEEIDFLLRTA
ASVLSRPPTRSDIRSAFAGLRPLIHPDNKDGKSTAALSREHAVLVSTSGLITVAGGKWTTYRLMAEQVIDRTIEVAGLPA
VPCPTRTLKLHACPAQPGNDVYGTEAPLLATLPGHDQPLHPELPYNAAMVRFAIRYEMARTIEDVLARRTRALFHDAAAA
EKMIDRIAGIFAEELQLTEERLASLIEAAHESARRFMAAQNSGA
>Mature_524_residues
MINAPLKREDGLAKLRDTAPWDVLIIGGGASGLGAAVDAAARGYRTLLIEARDFASGTSSCSTKLIHGGVRYLRQGDIGL
VRNALHERSHLLRNAAHLVHPLAFIIPAWRNIDRVFYGAGLKLYDLLAGRQGLAASRSLNRQDVIDALPGLRRASLCGGI
RYWDGQFDDARLAITLMRTATDLGASCLNYLPVTRLIKTGGRVAGAVLCDAESGEEFEVRARAVINATGVHADSVRRFDD
SAAVPLLTPSQGIHLVVDADFLPGQQAILVPKTEDGRVMFAIPWQGKVLLGTTDTPRPELSQLDDPQPLDEEIDFLLRTA
ASVLSRPPTRSDIRSAFAGLRPLIHPDNKDGKSTAALSREHAVLVSTSGLITVAGGKWTTYRLMAEQVIDRTIEVAGLPA
VPCPTRTLKLHACPAQPGNDVYGTEAPLLATLPGHDQPLHPELPYNAAMVRFAIRYEMARTIEDVLARRTRALFHDAAAA
EKMIDRIAGIFAEELQLTEERLASLIEAAHESARRFMAAQNSGA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=557, Percent_Identity=39.6768402154399, Blast_Score=356, Evalue=3e-98,
Organism=Homo sapiens, GI285002231, Length=557, Percent_Identity=39.6768402154399, Blast_Score=356, Evalue=3e-98,
Organism=Escherichia coli, GI2367226, Length=480, Percent_Identity=28.9583333333333, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1788574, Length=403, Percent_Identity=31.5136476426799, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17509253, Length=552, Percent_Identity=40.3985507246377, Blast_Score=336, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI115534726, Length=534, Percent_Identity=35.9550561797753, Blast_Score=311, Evalue=4e-85,
Organism=Saccharomyces cerevisiae, GI6322036, Length=599, Percent_Identity=34.2237061769616, Blast_Score=310, Evalue=5e-85,
Organism=Drosophila melanogaster, GI161077125, Length=548, Percent_Identity=39.4160583941606, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24653942, Length=548, Percent_Identity=39.4160583941606, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24653944, Length=548, Percent_Identity=39.4160583941606, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI20130025, Length=548, Percent_Identity=39.4160583941606, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24586295, Length=550, Percent_Identity=32.9090909090909, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI19921278, Length=536, Percent_Identity=33.5820895522388, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI45550977, Length=403, Percent_Identity=31.0173697270471, Blast_Score=174, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56668; Mature: 56668

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINAPLKREDGLAKLRDTAPWDVLIIGGGASGLGAAVDAAARGYRTLLIEARDFASGTSS
CCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEEHHHCCCCCH
CSTKLIHGGVRYLRQGDIGLVRNALHERSHLLRNAAHLVHPLAFIIPAWRNIDRVFYGAG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
LKLYDLLAGRQGLAASRSLNRQDVIDALPGLRRASLCGGIRYWDGQFDDARLAITLMRTA
CHHHHHHHCCCCCHHHHCCCHHHHHHHCCCCHHHHHHCCCEECCCCCCCCEEEEEEHHHH
TDLGASCLNYLPVTRLIKTGGRVAGAVLCDAESGEEFEVRARAVINATGVHADSVRRFDD
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEEEEEECCCCHHHHHHCCC
SAAVPLLTPSQGIHLVVDADFLPGQQAILVPKTEDGRVMFAIPWQGKVLLGTTDTPRPEL
CCCCEEECCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCCHH
SQLDDPQPLDEEIDFLLRTAASVLSRPPTRSDIRSAFAGLRPLIHPDNKDGKSTAALSRE
HCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCC
HAVLVSTSGLITVAGGKWTTYRLMAEQVIDRTIEVAGLPAVPCPTRTLKLHACPAQPGND
CEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCC
VYGTEAPLLATLPGHDQPLHPELPYNAAMVRFAIRYEMARTIEDVLARRTRALFHDAAAA
CCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMIDRIAGIFAEELQLTEERLASLIEAAHESARRFMAAQNSGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MINAPLKREDGLAKLRDTAPWDVLIIGGGASGLGAAVDAAARGYRTLLIEARDFASGTSS
CCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEEHHHCCCCCH
CSTKLIHGGVRYLRQGDIGLVRNALHERSHLLRNAAHLVHPLAFIIPAWRNIDRVFYGAG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
LKLYDLLAGRQGLAASRSLNRQDVIDALPGLRRASLCGGIRYWDGQFDDARLAITLMRTA
CHHHHHHHCCCCCHHHHCCCHHHHHHHCCCCHHHHHHCCCEECCCCCCCCEEEEEEHHHH
TDLGASCLNYLPVTRLIKTGGRVAGAVLCDAESGEEFEVRARAVINATGVHADSVRRFDD
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEEEEEECCCCHHHHHHCCC
SAAVPLLTPSQGIHLVVDADFLPGQQAILVPKTEDGRVMFAIPWQGKVLLGTTDTPRPEL
CCCCEEECCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCCHH
SQLDDPQPLDEEIDFLLRTAASVLSRPPTRSDIRSAFAGLRPLIHPDNKDGKSTAALSRE
HCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCC
HAVLVSTSGLITVAGGKWTTYRLMAEQVIDRTIEVAGLPAVPCPTRTLKLHACPAQPGND
CEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCC
VYGTEAPLLATLPGHDQPLHPELPYNAAMVRFAIRYEMARTIEDVLARRTRALFHDAAAA
CCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMIDRIAGIFAEELQLTEERLASLIEAAHESARRFMAAQNSGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]