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The map label for this gene is clpX

Identifier: 71907347

GI number: 71907347

Start: 1845157

End: 1846419

Strand: Reverse

Name: clpX

Synonym: Daro_1717

Alternate gene names: 71907347

Gene position: 1846419-1845157 (Counterclockwise)

Preceding gene: 71907348

Following gene: 71907346

Centisome position: 41.02

GC content: 57.64

Gene sequence:

>1263_bases
ATGTCTAAAGGCGGCCAGGAAAAACTGCTCTACTGCTCCTTCTGCGGCAAGAGCCAGCACGAAGTCAAAAAGCTCATCGC
CGGACCGTCGGTGTTCATCTGTGACGAGTGTATTTCGCTCTGCAACGACATCATCCGCGACGAACTCCCCGAAGAAGCCG
CCAAGGCCGGTCGTTCCGACTTGCCGACGCCGCGTGAAATCAGTTCTATCCTTGATCAGTATGTGATCGGCCAGGAAGTT
GCCAAGCGCATCCTGTCTGTCGCCGTCTACAACCACTACAAGCGCCTGCGTCACACGGCGAAGAATGCCGGTGATGTTGA
ACTGTCGAAGAGCAACATCCTGCTCATCGGCCCCACTGGCTCCGGCAAGACGCTGCTCGCTCAGACGCTGGCTCGCCTGC
TCAACGTGCCTTTCGTGATGGCCGACGCCACCACGCTGACCGAAGCCGGCTATGTCGGTGAAGACGTCGAAAACATCATC
CAGAAACTGCTGCAGAAGTGCGACTACGATGTCGAAAAAGCGCAGCAAGGCATTGTCTACATTGATGAAATCGACAAGAT
TTCGCGCAAATCAGACAACCCGTCGATCACCCGTGACGTCTCCGGCGAAGGGGTGCAACAAGCCCTGCTCAAGCTGATCG
AAGGCACCACTGCTTCGATTCCGCCGCAGGGTGGTCGCAAGCATCCAAACCAGGACTTTGTCCAGGTCGACACGACCAAC
ATCCTGTTCATCTGCGGCGGCGCATTCGCCGGTCTGGAAAAAGTCATCCAGAGCCGCTCGGAACGTGGCGGCATCGGCTT
TGGTGCCGAAGTGAAGAGCAAGGACGATGGCAAAGCCGTCGGCAAGATTCTGCTCGACGCCGAACCGGAAGACCTGATCA
AGTTCGGCCTGATTCCCGAACTGATCGGTCGCCTGCCGGTGGTTGCCACACTGCAGGAACTGGAAGAGTCCGCACTCGTC
CAGATCCTGACCGAACCGAAGAACGCACTGGTCAAGCAGTACCAGAAGCTCTTTTCGATGGAAGATGTCGAGCTGGAAAT
TCGCCCGACCGCGCTCTCCGCCATCGCCAAGAAGGCGCTGGCCCGCAAGACCGGTGCCCGCGGCCTGCGCTCGATCCTTG
AACACGCACTGCTCGACACGATGTACGAACTCCCGGGAATGGAGAGTGTCGAAAAGGTAGTCATCGACGAAAATACGATC
ACCGGCGACACTCCGCCTTTGCTCATTTACGCTGACCAGCCCAAGGTTTCCGGCTCGAACTGA

Upstream 100 bases:

>100_bases
CTGATCGCGACAACTTTCTTTCTGCAGCGGAAGCCGCAGAATATGGTTTGATCGACAAGGTATTGACCCGCCGCGACGCG
GCTTGAACGGAGAGCTAACG

Downstream 100 bases:

>100_bases
GCCGGGACTTGAATTGCGGTTCCCCGCCCCCACGTAGGGGGCACATACCTATTTCAAAGGCATCGTAATGTCGAACCCCA
ACACGCTCCCGGAAACCGTC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSKGGQEKLLYCSFCGKSQHEVKKLIAGPSVFICDECISLCNDIIRDELPEEAAKAGRSDLPTPREISSILDQYVIGQEV
AKRILSVAVYNHYKRLRHTAKNAGDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVMADATTLTEAGYVGEDVENII
QKLLQKCDYDVEKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTTASIPPQGGRKHPNQDFVQVDTTN
ILFICGGAFAGLEKVIQSRSERGGIGFGAEVKSKDDGKAVGKILLDAEPEDLIKFGLIPELIGRLPVVATLQELEESALV
QILTEPKNALVKQYQKLFSMEDVELEIRPTALSAIAKKALARKTGARGLRSILEHALLDTMYELPGMESVEKVVIDENTI
TGDTPPLLIYADQPKVSGSN

Sequences:

>Translated_420_residues
MSKGGQEKLLYCSFCGKSQHEVKKLIAGPSVFICDECISLCNDIIRDELPEEAAKAGRSDLPTPREISSILDQYVIGQEV
AKRILSVAVYNHYKRLRHTAKNAGDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVMADATTLTEAGYVGEDVENII
QKLLQKCDYDVEKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTTASIPPQGGRKHPNQDFVQVDTTN
ILFICGGAFAGLEKVIQSRSERGGIGFGAEVKSKDDGKAVGKILLDAEPEDLIKFGLIPELIGRLPVVATLQELEESALV
QILTEPKNALVKQYQKLFSMEDVELEIRPTALSAIAKKALARKTGARGLRSILEHALLDTMYELPGMESVEKVVIDENTI
TGDTPPLLIYADQPKVSGSN
>Mature_419_residues
SKGGQEKLLYCSFCGKSQHEVKKLIAGPSVFICDECISLCNDIIRDELPEEAAKAGRSDLPTPREISSILDQYVIGQEVA
KRILSVAVYNHYKRLRHTAKNAGDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVMADATTLTEAGYVGEDVENIIQ
KLLQKCDYDVEKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTTASIPPQGGRKHPNQDFVQVDTTNI
LFICGGAFAGLEKVIQSRSERGGIGFGAEVKSKDDGKAVGKILLDAEPEDLIKFGLIPELIGRLPVVATLQELEESALVQ
ILTEPKNALVKQYQKLFSMEDVELEIRPTALSAIAKKALARKTGARGLRSILEHALLDTMYELPGMESVEKVVIDENTIT
GDTPPLLIYADQPKVSGSN

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=330, Percent_Identity=52.1212121212121, Blast_Score=315, Evalue=5e-86,
Organism=Escherichia coli, GI1786642, Length=410, Percent_Identity=77.3170731707317, Blast_Score=636, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=107, Percent_Identity=47.6635514018692, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=315, Percent_Identity=46.984126984127, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=310, Percent_Identity=47.0967741935484, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=401, Percent_Identity=38.6533665835411, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=248, Percent_Identity=40.3225806451613, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=433, Percent_Identity=40.1847575057737, Blast_Score=280, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24648291, Length=322, Percent_Identity=46.2732919254658, Blast_Score=287, Evalue=9e-78,
Organism=Drosophila melanogaster, GI24648289, Length=322, Percent_Identity=46.2732919254658, Blast_Score=287, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_DECAR (Q47FB7)

Other databases:

- EMBL:   CP000089
- RefSeq:   YP_284934.1
- HSSP:   P0A6H5
- ProteinModelPortal:   Q47FB7
- SMR:   Q47FB7
- STRING:   Q47FB7
- GeneID:   3568535
- GenomeReviews:   CP000089_GR
- KEGG:   dar:Daro_1717
- NMPDR:   fig|159087.4.peg.1730
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   DARO159087:DARO_1717-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 45682; Mature: 45551

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGGQEKLLYCSFCGKSQHEVKKLIAGPSVFICDECISLCNDIIRDELPEEAAKAGRSD
CCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
LPTPREISSILDQYVIGQEVAKRILSVAVYNHYKRLRHTAKNAGDVELSKSNILLIGPTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCC
SGKTLLAQTLARLLNVPFVMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVY
CCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCEE
IDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTTASIPPQGGRKHPNQDFVQVDTTN
EEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCE
ILFICGGAFAGLEKVIQSRSERGGIGFGAEVKSKDDGKAVGKILLDAEPEDLIKFGLIPE
EEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
LIGRLPVVATLQELEESALVQILTEPKNALVKQYQKLFSMEDVELEIRPTALSAIAKKAL
HHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
ARKTGARGLRSILEHALLDTMYELPGMESVEKVVIDENTITGDTPPLLIYADQPKVSGSN
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
SKGGQEKLLYCSFCGKSQHEVKKLIAGPSVFICDECISLCNDIIRDELPEEAAKAGRSD
CCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
LPTPREISSILDQYVIGQEVAKRILSVAVYNHYKRLRHTAKNAGDVELSKSNILLIGPTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCC
SGKTLLAQTLARLLNVPFVMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVY
CCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCEE
IDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTTASIPPQGGRKHPNQDFVQVDTTN
EEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCE
ILFICGGAFAGLEKVIQSRSERGGIGFGAEVKSKDDGKAVGKILLDAEPEDLIKFGLIPE
EEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
LIGRLPVVATLQELEESALVQILTEPKNALVKQYQKLFSMEDVELEIRPTALSAIAKKAL
HHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
ARKTGARGLRSILEHALLDTMYELPGMESVEKVVIDENTITGDTPPLLIYADQPKVSGSN
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA