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The map label for this gene is cbiX [H]

Identifier: 71907322

GI number: 71907322

Start: 1820637

End: 1821548

Strand: Reverse

Name: cbiX [H]

Synonym: Daro_1692

Alternate gene names: 71907322

Gene position: 1821548-1820637 (Counterclockwise)

Preceding gene: 71907323

Following gene: 71907321

Centisome position: 40.47

GC content: 62.83

Gene sequence:

>912_bases
ATGAACACTGAAACCACCATCCTGCTGGTCGGCCACGGCTCGCGCGGCCGGGAAGGCAACAAGGAAACGATCAATTTTGC
TGCCCAGTGGCGCGAACGCCACCCGGCATGGCGCATCGAGGTCTGCTTCATCGAGCACGCCGAGGTGCTGCTCGACGATG
GTCTTGACCGCGCAGCCCGCCAGGCGAAAAAAGTGCTGGTCATTCCCTTCATTCTGAACGCCGCCGGCCACGTCAAAATG
GAGTTGCCAGCCGCGATTGAAAGTGCCCGCTTGCGCCATCCGGCGGTCGAATTCGCCGTCACCCGTCACCTCGGCATGGG
GCGCGAAATGTTCGCCGTGCTGCAGGGCCAGCTGGATCGCCTGATCAAGCAGATGGCCGTTCCCGACCCGATGACCACGG
GCGTCGTGCTGCTCGGTCGCGGCTCTTCGGATGCCGGCGCCAATGGCGAACTGGCCAAGATGGCACGCTGGATTTTCGAG
GAGAACGAACACGAACTAGTCGATCTCGCCTTCACCGGTGTGACCTGGCCCCGCCTGGAAACCGTGGTGCAGCGCCAGGT
CAAGCTCGGCATGATGCAGATTGCCATCGTCCCGGTCTATCTGTTCACCGGCGTGCTGATCGAGCGGATTCAGGCCCAGG
TGGAACGTCTGCGGCAACAATATCCGCAGATCAGCTTCGCGCTCGGCACGCACTTCGGCTTCGACCAGGGGGTTTTCGAG
CTGCTCGACGAGAAGGTCAACGGCGAGCTGCCGGAAGGCCGCATGCTCGAATGCGATGGCTGCAAGTATCGCGAGCTGGC
CGAAGACGAACACCTGCACGATCACAGCCATACCGCGACCGGCGGTTGCGGCCACAGCCACAGCCACGAACACGCCCACG
ATCACGTCCATTGCCAACACGCCCACGCCTGA

Upstream 100 bases:

>100_bases
ACTGGCCAGACCTGATCCGTTCCAAGCTCTACGACCCCGCCTTTACGCACCGCTTCCGCAAGGCAAGCCCGGCCTCTGCC
GTCACCCCGGAGATCAACCC

Downstream 100 bases:

>100_bases
GCCGACATGACCACCAACACTATCACCGAACAACTGACCGCCGCCGGCCGTGCCATCGAGCACGATTCATTTGCCGTGAT
CGATGCAGAAGCCGGCCCGC

Product: cobalamin (vitamin B12) biosynthesis CbiX protein

Products: NA

Alternate protein names: CbiXL [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MNTETTILLVGHGSRGREGNKETINFAAQWRERHPAWRIEVCFIEHAEVLLDDGLDRAARQAKKVLVIPFILNAAGHVKM
ELPAAIESARLRHPAVEFAVTRHLGMGREMFAVLQGQLDRLIKQMAVPDPMTTGVVLLGRGSSDAGANGELAKMARWIFE
ENEHELVDLAFTGVTWPRLETVVQRQVKLGMMQIAIVPVYLFTGVLIERIQAQVERLRQQYPQISFALGTHFGFDQGVFE
LLDEKVNGELPEGRMLECDGCKYRELAEDEHLHDHSHTATGGCGHSHSHEHAHDHVHCQHAHA

Sequences:

>Translated_303_residues
MNTETTILLVGHGSRGREGNKETINFAAQWRERHPAWRIEVCFIEHAEVLLDDGLDRAARQAKKVLVIPFILNAAGHVKM
ELPAAIESARLRHPAVEFAVTRHLGMGREMFAVLQGQLDRLIKQMAVPDPMTTGVVLLGRGSSDAGANGELAKMARWIFE
ENEHELVDLAFTGVTWPRLETVVQRQVKLGMMQIAIVPVYLFTGVLIERIQAQVERLRQQYPQISFALGTHFGFDQGVFE
LLDEKVNGELPEGRMLECDGCKYRELAEDEHLHDHSHTATGGCGHSHSHEHAHDHVHCQHAHA
>Mature_303_residues
MNTETTILLVGHGSRGREGNKETINFAAQWRERHPAWRIEVCFIEHAEVLLDDGLDRAARQAKKVLVIPFILNAAGHVKM
ELPAAIESARLRHPAVEFAVTRHLGMGREMFAVLQGQLDRLIKQMAVPDPMTTGVVLLGRGSSDAGANGELAKMARWIFE
ENEHELVDLAFTGVTWPRLETVVQRQVKLGMMQIAIVPVYLFTGVLIERIQAQVERLRQQYPQISFALGTHFGFDQGVFE
LLDEKVNGELPEGRMLECDGCKYRELAEDEHLHDHSHTATGGCGHSHSHEHAHDHVHCQHAHA

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis [H]

COG id: COG2138

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiX family. CbiXL subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002762 [H]

Pfam domain/function: PF01903 CbiX [H]

EC number: =4.99.1.3 [H]

Molecular weight: Translated: 33978; Mature: 33978

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTETTILLVGHGSRGREGNKETINFAAQWRERHPAWRIEVCFIEHAEVLLDDGLDRAAR
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHCCHHHHHH
QAKKVLVIPFILNAAGHVKMELPAAIESARLRHPAVEFAVTRHLGMGREMFAVLQGQLDR
HHCCEEEEEHHHCCCCCEEEECCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
LIKQMAVPDPMTTGVVLLGRGSSDAGANGELAKMARWIFEENEHELVDLAFTGVTWPRLE
HHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
TVVQRQVKLGMMQIAIVPVYLFTGVLIERIQAQVERLRQQYPQISFALGTHFGFDQGVFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCCCHHHHHH
LLDEKVNGELPEGRMLECDGCKYRELAEDEHLHDHSHTATGGCGHSHSHEHAHDHVHCQH
HHHHHHCCCCCCCCEEECCCCCHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AHA
CCC
>Mature Secondary Structure
MNTETTILLVGHGSRGREGNKETINFAAQWRERHPAWRIEVCFIEHAEVLLDDGLDRAAR
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHCCHHHHHH
QAKKVLVIPFILNAAGHVKMELPAAIESARLRHPAVEFAVTRHLGMGREMFAVLQGQLDR
HHCCEEEEEHHHCCCCCEEEECCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
LIKQMAVPDPMTTGVVLLGRGSSDAGANGELAKMARWIFEENEHELVDLAFTGVTWPRLE
HHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
TVVQRQVKLGMMQIAIVPVYLFTGVLIERIQAQVERLRQQYPQISFALGTHFGFDQGVFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCCCHHHHHH
LLDEKVNGELPEGRMLECDGCKYRELAEDEHLHDHSHTATGGCGHSHSHEHAHDHVHCQH
HHHHHHCCCCCCCCEEECCCCCHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AHA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9742225; 12917443 [H]