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The map label for this gene is cbiC [H]

Identifier: 71907321

GI number: 71907321

Start: 1819953

End: 1820630

Strand: Reverse

Name: cbiC [H]

Synonym: Daro_1691

Alternate gene names: 71907321

Gene position: 1820630-1819953 (Counterclockwise)

Preceding gene: 71907322

Following gene: 71907320

Centisome position: 40.45

GC content: 63.27

Gene sequence:

>678_bases
ATGACCACCAACACTATCACCGAACAACTGACCGCCGCCGGCCGTGCCATCGAGCACGATTCATTTGCCGTGATCGATGC
AGAAGCCGGCCCGCACACCTATACCGACGAGCAGTGGCCACTGGTTCGCCGCATGATCCACGCCAACGCCGACTTCGAGT
TCAACGGCCTGACCGCCTTTCATCAGGAAGCCATGCGCGCCGGCTTTCAGGCGGTGTTGAAGGGCAATACGCCGATCGTC
GCCGATGTCGAGATGATCTGCGTCGGCCTCTCCAAGCCACGCCTGCAGCACTTCGGCCTGAGCACGCACCACTACATTTC
CGATGAAGACGTCATCGAGCAGGCCAGGGCCGAAGACACCACCCGCGCCGTCCAGGCCATGCGCAAGGCCCAGCGTCTGG
GCAAGCTCGATGGCGCCATCGTTGGCATCGGCAATGCGCCGACTGCACTGATCGAACTGGTCCGCCTGATTCGCGAGGAA
GGCGTCCGTCCGGCGCTGGTGGTCGCGATGCCGGTCGGTTTCGTTTCAGCGGCCGAATCGAAGGATCTGATGATGACCGT
CAACGAAGTGCCCTGGGTCGCCATCAAGGGGCGCAAGGGCGGCTCGACCCTGGTGGTTGCGGCAATCCACGCCATGCTGT
CGCTGGCCGAGGCCGAACAGCACAAGTCGGTGGCCTGA

Upstream 100 bases:

>100_bases
CGATCACAGCCATACCGCGACCGGCGGTTGCGGCCACAGCCACAGCCACGAACACGCCCACGATCACGTCCATTGCCAAC
ACGCCCACGCCTGAGCCGAC

Downstream 100 bases:

>100_bases
GTCCGGCATGAGCGATGAAACCAGGGTGGGCGAGGCGGCGGAACAAGCCGCCACGCCTGAAAAAATACGCAAGGGAAGCG
CCAGGCGGGAACGCGGCAAT

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTTNTITEQLTAAGRAIEHDSFAVIDAEAGPHTYTDEQWPLVRRMIHANADFEFNGLTAFHQEAMRAGFQAVLKGNTPIV
ADVEMICVGLSKPRLQHFGLSTHHYISDEDVIEQARAEDTTRAVQAMRKAQRLGKLDGAIVGIGNAPTALIELVRLIREE
GVRPALVVAMPVGFVSAAESKDLMMTVNEVPWVAIKGRKGGSTLVVAAIHAMLSLAEAEQHKSVA

Sequences:

>Translated_225_residues
MTTNTITEQLTAAGRAIEHDSFAVIDAEAGPHTYTDEQWPLVRRMIHANADFEFNGLTAFHQEAMRAGFQAVLKGNTPIV
ADVEMICVGLSKPRLQHFGLSTHHYISDEDVIEQARAEDTTRAVQAMRKAQRLGKLDGAIVGIGNAPTALIELVRLIREE
GVRPALVVAMPVGFVSAAESKDLMMTVNEVPWVAIKGRKGGSTLVVAAIHAMLSLAEAEQHKSVA
>Mature_224_residues
TTNTITEQLTAAGRAIEHDSFAVIDAEAGPHTYTDEQWPLVRRMIHANADFEFNGLTAFHQEAMRAGFQAVLKGNTPIVA
DVEMICVGLSKPRLQHFGLSTHHYISDEDVIEQARAEDTTRAVQAMRKAQRLGKLDGAIVGIGNAPTALIELVRLIREEG
VRPALVVAMPVGFVSAAESKDLMMTVNEVPWVAIKGRKGGSTLVVAAIHAMLSLAEAEQHKSVA

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 24359; Mature: 24228

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNTITEQLTAAGRAIEHDSFAVIDAEAGPHTYTDEQWPLVRRMIHANADFEFNGLTAF
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCEECCHHHH
HQEAMRAGFQAVLKGNTPIVADVEMICVGLSKPRLQHFGLSTHHYISDEDVIEQARAEDT
HHHHHHHHHHHHHCCCCCEEECHHHHEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHH
TRAVQAMRKAQRLGKLDGAIVGIGNAPTALIELVRLIREEGVRPALVVAMPVGFVSAAES
HHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECHHHHHCCCC
KDLMMTVNEVPWVAIKGRKGGSTLVVAAIHAMLSLAEAEQHKSVA
CCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTNTITEQLTAAGRAIEHDSFAVIDAEAGPHTYTDEQWPLVRRMIHANADFEFNGLTAF
CCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCEECCHHHH
HQEAMRAGFQAVLKGNTPIVADVEMICVGLSKPRLQHFGLSTHHYISDEDVIEQARAEDT
HHHHHHHHHHHHHCCCCCEEECHHHHEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHH
TRAVQAMRKAQRLGKLDGAIVGIGNAPTALIELVRLIREEGVRPALVVAMPVGFVSAAES
HHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECHHHHHCCCC
KDLMMTVNEVPWVAIKGRKGGSTLVVAAIHAMLSLAEAEQHKSVA
CCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]