Click here to switch to the map view.

The map label for this gene is cobL [H]

Identifier: 71907319

GI number: 71907319

Start: 1817491

End: 1818777

Strand: Reverse

Name: cobL [H]

Synonym: Daro_1689

Alternate gene names: 71907319

Gene position: 1818777-1817491 (Counterclockwise)

Preceding gene: 71907320

Following gene: 71907318

Centisome position: 40.41

GC content: 66.05

Gene sequence:

>1287_bases
ATGAAGCGCTCTGATCAATGTGCCTTGATTGGCATTCTCGATGACGGCTGGGCGGGTTTGTCCGAAACCGCCCGCCAGCG
TCTGGCGGCAGCCGATATCGTGATCGGTGCCGGGCGGACGCTGGAACTGGTTCGCCCGCACTTGTCCGCCGGCGCAACGC
TGAAGGACATGGACGGCGCGCTCGGCCAGGTTAGCGGCTGGATACTGGCTGCCCGCGACGCCGGCCAAACGGTGGCCGCG
CTGGCCACCGGCGACCCGCTCTGCCACGGCATCGCCTCGTGGCTGACCGGCAAGCTGGGGCGCGACGGATTCGATATCCT
GCCGGCGGTATCGACCTTGCAGCTGGCCTTTGCCCGTTTCAAAACACCGTGGCAGGACATCAAGATTGCCACCTGCCATA
GCGCCGATGCCGGCGAATGGTTTGTCGGCGCCACTCCGGCCCACGGCCTCTACAAGCTGATGCGGACCATCGCCCGGCAT
CCGCGCGTCGCGCTCTTTACCGGCCCGGAAAACACGCCGGCCCGGCTGGCCCGGGCGCTGATCACCGCCGGTTACGGCGA
TGACGCCAAGCTGTCGATCGCCTGTCGTCTCTTGCTGGCCGATGAGCAGATCTTCGCTGGCCTAAGCCCCGCCGAGGCCG
CGACCATGGAGTTCCCGCAGCCGAACGTCGTGCTGGTCGACCGTGCAGCGGAGGCGCCCCGCCCGAGCTTTGGCCTGGAA
GATCTCGAATACATCCAGCGCTCGCCGGAAAAAGGCCTGATCACCAAGCAGGAAGCCCGCGCGCTGTCACTGGCCAAGCT
GCGCCTCGCACCCGATGCCATCGTCTGGGACATCGGTGCCGGCTCCGGCTCGGTCGGCCTCGAATGCGCCCGGCTGGCCC
CGTTCGGCCACGTCTGGGCGATCGAGAAAAACGAAGGCGATGCCGCCAATGCCAGGGCCAATGCCGAACGTTTCCGCATC
GGCAACTACACGCTGTGCGAAGGCAAGGCCCCGGCGCAGCTCGATAGCTGGCCAGACCCGGATGCCGTCTTCATCGGCGG
CTCCGGCGGCGAACTGGCCGAGTTGATCAAGCTGATCCTCGGCCGCCTGAAGCCGGGTGGCCGGCTGGTCATGAATTTCG
TCACCCTGGAAAACCTCGCCACGGCCACGGCAACGCTCAAGGAATGCGGCGCCACCTGGGATGTCGTCCAGCTTCAGGCC
AGCCGCAGCCAGCCCATTCTCGACATGCACCGGATGGCCGCGCAGAACCCGGTGTGGATTGTTAGCGCAAGCAAGGAAAA
TCTATGA

Upstream 100 bases:

>100_bases
AAGGCCATCCGCAGTCTCAAGGACAAGTACCCCGGCAATTACCGCCTGGCCGTGCTGGTCTGCGATTTCGAAGGTCAATT
TATTTGTCGGGTGAATGAAG

Downstream 100 bases:

>100_bases
CTCAAGCCGCAAAAACCCACGGCAAGCTGATCGGCGCCTCACTCGGCCCCGGCGATCCCGAACTGATCACCCGCCGTGCC
TGGGCCGCCCTTCAATCAGG

Product: precorrin-6Y C5,15-methyltransferase (decarboxylating)

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKRSDQCALIGILDDGWAGLSETARQRLAAADIVIGAGRTLELVRPHLSAGATLKDMDGALGQVSGWILAARDAGQTVAA
LATGDPLCHGIASWLTGKLGRDGFDILPAVSTLQLAFARFKTPWQDIKIATCHSADAGEWFVGATPAHGLYKLMRTIARH
PRVALFTGPENTPARLARALITAGYGDDAKLSIACRLLLADEQIFAGLSPAEAATMEFPQPNVVLVDRAAEAPRPSFGLE
DLEYIQRSPEKGLITKQEARALSLAKLRLAPDAIVWDIGAGSGSVGLECARLAPFGHVWAIEKNEGDAANARANAERFRI
GNYTLCEGKAPAQLDSWPDPDAVFIGGSGGELAELIKLILGRLKPGGRLVMNFVTLENLATATATLKECGATWDVVQLQA
SRSQPILDMHRMAAQNPVWIVSASKENL

Sequences:

>Translated_428_residues
MKRSDQCALIGILDDGWAGLSETARQRLAAADIVIGAGRTLELVRPHLSAGATLKDMDGALGQVSGWILAARDAGQTVAA
LATGDPLCHGIASWLTGKLGRDGFDILPAVSTLQLAFARFKTPWQDIKIATCHSADAGEWFVGATPAHGLYKLMRTIARH
PRVALFTGPENTPARLARALITAGYGDDAKLSIACRLLLADEQIFAGLSPAEAATMEFPQPNVVLVDRAAEAPRPSFGLE
DLEYIQRSPEKGLITKQEARALSLAKLRLAPDAIVWDIGAGSGSVGLECARLAPFGHVWAIEKNEGDAANARANAERFRI
GNYTLCEGKAPAQLDSWPDPDAVFIGGSGGELAELIKLILGRLKPGGRLVMNFVTLENLATATATLKECGATWDVVQLQA
SRSQPILDMHRMAAQNPVWIVSASKENL
>Mature_428_residues
MKRSDQCALIGILDDGWAGLSETARQRLAAADIVIGAGRTLELVRPHLSAGATLKDMDGALGQVSGWILAARDAGQTVAA
LATGDPLCHGIASWLTGKLGRDGFDILPAVSTLQLAFARFKTPWQDIKIATCHSADAGEWFVGATPAHGLYKLMRTIARH
PRVALFTGPENTPARLARALITAGYGDDAKLSIACRLLLADEQIFAGLSPAEAATMEFPQPNVVLVDRAAEAPRPSFGLE
DLEYIQRSPEKGLITKQEARALSLAKLRLAPDAIVWDIGAGSGSVGLECARLAPFGHVWAIEKNEGDAANARANAERFRI
GNYTLCEGKAPAQLDSWPDPDAVFIGGSGGELAELIKLILGRLKPGGRLVMNFVTLENLATATATLKECGATWDVVQLQA
SRSQPILDMHRMAAQNPVWIVSASKENL

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 45565; Mature: 45565

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSDQCALIGILDDGWAGLSETARQRLAAADIVIGAGRTLELVRPHLSAGATLKDMDGA
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEEECCCEEEHHCHHHCCCCCHHHHCCH
LGQVSGWILAARDAGQTVAALATGDPLCHGIASWLTGKLGRDGFDILPAVSTLQLAFARF
HHHCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
KTPWQDIKIATCHSADAGEWFVGATPAHGLYKLMRTIARHPRVALFTGPENTPARLARAL
CCCHHHEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
ITAGYGDDAKLSIACRLLLADEQIFAGLSPAEAATMEFPQPNVVLVDRAAEAPRPSFGLE
HHCCCCCCCEEEEEEEEEEECHHHHCCCCCCHHHEECCCCCCEEEEECCCCCCCCCCCHH
DLEYIQRSPEKGLITKQEARALSLAKLRLAPDAIVWDIGAGSGSVGLECARLAPFGHVWA
HHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCEEEEEECCCCCCCCCEEEEECCCCEEEE
IEKNEGDAANARANAERFRIGNYTLCEGKAPAQLDSWPDPDAVFIGGSGGELAELIKLIL
EECCCCCCCCCCCCHHHEEECCEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
GRLKPGGRLVMNFVTLENLATATATLKECGATWDVVQLQASRSQPILDMHRMAAQNPVWI
HHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEE
VSASKENL
EECCCCCC
>Mature Secondary Structure
MKRSDQCALIGILDDGWAGLSETARQRLAAADIVIGAGRTLELVRPHLSAGATLKDMDGA
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEEECCCEEEHHCHHHCCCCCHHHHCCH
LGQVSGWILAARDAGQTVAALATGDPLCHGIASWLTGKLGRDGFDILPAVSTLQLAFARF
HHHCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
KTPWQDIKIATCHSADAGEWFVGATPAHGLYKLMRTIARHPRVALFTGPENTPARLARAL
CCCHHHEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
ITAGYGDDAKLSIACRLLLADEQIFAGLSPAEAATMEFPQPNVVLVDRAAEAPRPSFGLE
HHCCCCCCCEEEEEEEEEEECHHHHCCCCCCHHHEECCCCCCEEEEECCCCCCCCCCCHH
DLEYIQRSPEKGLITKQEARALSLAKLRLAPDAIVWDIGAGSGSVGLECARLAPFGHVWA
HHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCEEEEEECCCCCCCCCEEEEECCCCEEEE
IEKNEGDAANARANAERFRIGNYTLCEGKAPAQLDSWPDPDAVFIGGSGGELAELIKLIL
EECCCCCCCCCCCCHHHEEECCEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
GRLKPGGRLVMNFVTLENLATATATLKECGATWDVVQLQASRSQPILDMHRMAAQNPVWI
HHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEE
VSASKENL
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]