Click here to switch to the map view.

The map label for this gene is cbiL [H]

Identifier: 71907318

GI number: 71907318

Start: 1816691

End: 1817494

Strand: Reverse

Name: cbiL [H]

Synonym: Daro_1688

Alternate gene names: 71907318

Gene position: 1817494-1816691 (Counterclockwise)

Preceding gene: 71907319

Following gene: 71907317

Centisome position: 40.38

GC content: 63.31

Gene sequence:

>804_bases
ATGACTCAAGCCGCAAAAACCCACGGCAAGCTGATCGGCGCCTCACTCGGCCCCGGCGATCCCGAACTGATCACCCGCCG
TGCCTGGGCCGCCCTTCAATCAGGTGCCCGCTGGCTGTACCCGGTCAAAAAGGCCGAAGAATCGTCTTACGCGCTGTCCA
TCGTCGAACGTGGCGGCATTGCCATTCCGGCTGATGCCGTCGAACTGGTCTTCCCGATGACCCGGGATGCCGAAATCCTG
GCCAAGGCCTGGGTCCGTGCCGCCGAGCGTACCGTCCAACTGCTGGCCGAAGGACGCGATCTGGTTTTCCTGGTCGAAGG
CGATGCGTCCACCTTCGCCACCTTCGGCCACCTCGCCCGCGTCGTCCGCGAGTTGGTACCGCAGATCGAGGTCGAGACCA
TTCCCGGCGTTTCCTCCTTCGCTGCGGCGGCCGCAACCACCGGCACAACGCTGGCGGAAGAGGACGAAACCTTTGCCATC
ATTCCGGCCGCTTATGGGGTCGCCGTCATCGACCACCTGCTCGACGAGTTCGACACCCTGGCCCTGCTCAAGGTCAAACC
GCTGGTCGACGAGGTGATTGACCTGCTTGAACGGCGCGACCTGCTCGCCACCTCGGTCTTCATCGAGAAAGTCGGCTCAC
CGGATGAGCGGGTGGTGCACGACGTGGCCAGCCTGAAGGGCGAAAAGGTCAATTACCTGTCCCTGATGCTGGTCCAGAAC
CCGAAACGCGTCCGCGGCGAACTGCGTCGCGGCTGCCGCAAACGCAAGGAAGCCATCGAGTCTTCGCTACCCGCAATCAA
CTAG

Upstream 100 bases:

>100_bases
TCGTCCAGCTTCAGGCCAGCCGCAGCCAGCCCATTCTCGACATGCACCGGATGGCCGCGCAGAACCCGGTGTGGATTGTT
AGCGCAAGCAAGGAAAATCT

Downstream 100 bases:

>100_bases
AACGGACGCCACCTCATGAGAATCGCAGTCGTTTCAATCACCAAACATGGCATCGCGCTGGCCGGCAAGGTCGTTGCCGC
CCTGCCCGGCGCCCAACTCT

Product: precorrin-2 C20-methyltransferase / cobalt-factor II C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTQAAKTHGKLIGASLGPGDPELITRRAWAALQSGARWLYPVKKAEESSYALSIVERGGIAIPADAVELVFPMTRDAEIL
AKAWVRAAERTVQLLAEGRDLVFLVEGDASTFATFGHLARVVRELVPQIEVETIPGVSSFAAAAATTGTTLAEEDETFAI
IPAAYGVAVIDHLLDEFDTLALLKVKPLVDEVIDLLERRDLLATSVFIEKVGSPDERVVHDVASLKGEKVNYLSLMLVQN
PKRVRGELRRGCRKRKEAIESSLPAIN

Sequences:

>Translated_267_residues
MTQAAKTHGKLIGASLGPGDPELITRRAWAALQSGARWLYPVKKAEESSYALSIVERGGIAIPADAVELVFPMTRDAEIL
AKAWVRAAERTVQLLAEGRDLVFLVEGDASTFATFGHLARVVRELVPQIEVETIPGVSSFAAAAATTGTTLAEEDETFAI
IPAAYGVAVIDHLLDEFDTLALLKVKPLVDEVIDLLERRDLLATSVFIEKVGSPDERVVHDVASLKGEKVNYLSLMLVQN
PKRVRGELRRGCRKRKEAIESSLPAIN
>Mature_266_residues
TQAAKTHGKLIGASLGPGDPELITRRAWAALQSGARWLYPVKKAEESSYALSIVERGGIAIPADAVELVFPMTRDAEILA
KAWVRAAERTVQLLAEGRDLVFLVEGDASTFATFGHLARVVRELVPQIEVETIPGVSSFAAAAATTGTTLAEEDETFAII
PAAYGVAVIDHLLDEFDTLALLKVKPLVDEVIDLLERRDLLATSVFIEKVGSPDERVVHDVASLKGEKVNYLSLMLVQNP
KRVRGELRRGCRKRKEAIESSLPAIN

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 28992; Mature: 28861

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAAKTHGKLIGASLGPGDPELITRRAWAALQSGARWLYPVKKAEESSYALSIVERGGI
CCCCHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHCCCCHHEEHHHHCCCE
AIPADAVELVFPMTRDAEILAKAWVRAAERTVQLLAEGRDLVFLVEGDASTFATFGHLAR
ECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
VVRELVPQIEVETIPGVSSFAAAAATTGTTLAEEDETFAIIPAAYGVAVIDHLLDEFDTL
HHHHHHCCCEEECCCCHHHHHHHHHHCCCEECCCCCCEEEEHHHHHHHHHHHHHHHHHHH
ALLKVKPLVDEVIDLLERRDLLATSVFIEKVGSPDERVVHDVASLKGEKVNYLSLMLVQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHEEEEEECC
PKRVRGELRRGCRKRKEAIESSLPAIN
CHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TQAAKTHGKLIGASLGPGDPELITRRAWAALQSGARWLYPVKKAEESSYALSIVERGGI
CCCHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHCCCCHHEEHHHHCCCE
AIPADAVELVFPMTRDAEILAKAWVRAAERTVQLLAEGRDLVFLVEGDASTFATFGHLAR
ECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
VVRELVPQIEVETIPGVSSFAAAAATTGTTLAEEDETFAIIPAAYGVAVIDHLLDEFDTL
HHHHHHCCCEEECCCCHHHHHHHHHHCCCEECCCCCCEEEEHHHHHHHHHHHHHHHHHHH
ALLKVKPLVDEVIDLLERRDLLATSVFIEKVGSPDERVVHDVASLKGEKVNYLSLMLVQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHEEEEEECC
PKRVRGELRRGCRKRKEAIESSLPAIN
CHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]