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The map label for this gene is insK [H]

Identifier: 71906939

GI number: 71906939

Start: 1417170

End: 1417997

Strand: Reverse

Name: insK [H]

Synonym: Daro_1305

Alternate gene names: 71906939

Gene position: 1417997-1417170 (Counterclockwise)

Preceding gene: 71906940

Following gene: 71906936

Centisome position: 31.5

GC content: 58.21

Gene sequence:

>828_bases
ATGATCGACAAGGCCCACGATCTGCCTGTCGTCAGGCAAGTCCAGTTGCTTGAACTTTCCCGCTCTTCTGTCTATTACCA
GCCGCAGCCCATCCCCGAAGACGATCTTCGGTTGATGCGTCGAATCGATGAACTGCATCTGGAATACCCCTTTGCCGGGG
CGCGGATGCTGCGTGACATGCTCAAGTTGGAAGGCCATGGAATCGGCCGCAAGCATGTCGGTACGCTGATGAAGAAGCTC
GATATTCAGGCCATCTACCGCAAGGCCAACACCAGCCGGCGCAACCAGGCGCACCGCATCTATCCCTACCTGCTGCGCGA
CCTCGCCATCGACCGTCCGAATCAGGTCTGGGCCATGGATACGACCTACATCCCAATGCGCCGGGGCTTCGTCTATTTGA
GCGCGGTGCTTGATTGGGCCACTCGCCGGGTGCTGGCTTGGCGCCTATCGAACAGTTTGACCTCCGATCCTTGTGTGGAT
GCCCTGGAAGAAGCCATCATGAAGTACGGCCGACCAGAAATCATGAACACCGACCAAGGCAGCCAATTCACCAGCTCCGC
CTTCATTGGCTTGCTTCAGGAGAGCACCATTCAGGTCAGCATGGATGGCAAGGGCTGCTGGCGGGACAACGTCTTCGTTG
AGCGCCTCTGGAAATCGGTCAAGTATGAGGAGATTTACCTGCACGGCTACGACACCGTTTCCGAGGTCCGGCAGGCGCTG
GCCCGCTATTTCGATTTCTACAATCGCCGTCGCCCGCACTCAACGCTTGACGGGCAAACCCCGGATACGGCTTACTTCAA
CCAGCCGCTGCTCGCCGCAGCGGCTTAA

Upstream 100 bases:

>100_bases
CGGACCTGAAGGATTTGCATGCAAAGATCGGCCAGCAGGCGTTGGAGATCGATTTTTTGGCCGGCGCGCTCGGTCGCATC
GGCGATGCGAGCGCAAAACG

Downstream 100 bases:

>100_bases
CCCGCAGAGAAATCACTTAAGAAAACCGAATTTCTGTCCAACTGCGCGGGGCCACCTCTGTTTGAACTGAATCTGGCAAC
ACGTCCAACTACGGAATTGG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MIDKAHDLPVVRQVQLLELSRSSVYYQPQPIPEDDLRLMRRIDELHLEYPFAGARMLRDMLKLEGHGIGRKHVGTLMKKL
DIQAIYRKANTSRRNQAHRIYPYLLRDLAIDRPNQVWAMDTTYIPMRRGFVYLSAVLDWATRRVLAWRLSNSLTSDPCVD
ALEEAIMKYGRPEIMNTDQGSQFTSSAFIGLLQESTIQVSMDGKGCWRDNVFVERLWKSVKYEEIYLHGYDTVSEVRQAL
ARYFDFYNRRRPHSTLDGQTPDTAYFNQPLLAAAA

Sequences:

>Translated_275_residues
MIDKAHDLPVVRQVQLLELSRSSVYYQPQPIPEDDLRLMRRIDELHLEYPFAGARMLRDMLKLEGHGIGRKHVGTLMKKL
DIQAIYRKANTSRRNQAHRIYPYLLRDLAIDRPNQVWAMDTTYIPMRRGFVYLSAVLDWATRRVLAWRLSNSLTSDPCVD
ALEEAIMKYGRPEIMNTDQGSQFTSSAFIGLLQESTIQVSMDGKGCWRDNVFVERLWKSVKYEEIYLHGYDTVSEVRQAL
ARYFDFYNRRRPHSTLDGQTPDTAYFNQPLLAAAA
>Mature_275_residues
MIDKAHDLPVVRQVQLLELSRSSVYYQPQPIPEDDLRLMRRIDELHLEYPFAGARMLRDMLKLEGHGIGRKHVGTLMKKL
DIQAIYRKANTSRRNQAHRIYPYLLRDLAIDRPNQVWAMDTTYIPMRRGFVYLSAVLDWATRRVLAWRLSNSLTSDPCVD
ALEEAIMKYGRPEIMNTDQGSQFTSSAFIGLLQESTIQVSMDGKGCWRDNVFVERLWKSVKYEEIYLHGYDTVSEVRQAL
ARYFDFYNRRRPHSTLDGQTPDTAYFNQPLLAAAA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=199, Percent_Identity=32.6633165829146, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1789981, Length=267, Percent_Identity=31.0861423220974, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788405, Length=216, Percent_Identity=31.0185185185185, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787263, Length=216, Percent_Identity=31.0185185185185, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786753, Length=216, Percent_Identity=31.0185185185185, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786570, Length=216, Percent_Identity=31.0185185185185, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786490, Length=216, Percent_Identity=31.0185185185185, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32008; Mature: 32008

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKAHDLPVVRQVQLLELSRSSVYYQPQPIPEDDLRLMRRIDELHLEYPFAGARMLRDM
CCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LKLEGHGIGRKHVGTLMKKLDIQAIYRKANTSRRNQAHRIYPYLLRDLAIDRPNQVWAMD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
TTYIPMRRGFVYLSAVLDWATRRVLAWRLSNSLTSDPCVDALEEAIMKYGRPEIMNTDQG
CEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
SQFTSSAFIGLLQESTIQVSMDGKGCWRDNVFVERLWKSVKYEEIYLHGYDTVSEVRQAL
CHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
ARYFDFYNRRRPHSTLDGQTPDTAYFNQPLLAAAA
HHHHHHHHCCCCCCCCCCCCCCCHHCCCCHHHHCC
>Mature Secondary Structure
MIDKAHDLPVVRQVQLLELSRSSVYYQPQPIPEDDLRLMRRIDELHLEYPFAGARMLRDM
CCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LKLEGHGIGRKHVGTLMKKLDIQAIYRKANTSRRNQAHRIYPYLLRDLAIDRPNQVWAMD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
TTYIPMRRGFVYLSAVLDWATRRVLAWRLSNSLTSDPCVDALEEAIMKYGRPEIMNTDQG
CEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
SQFTSSAFIGLLQESTIQVSMDGKGCWRDNVFVERLWKSVKYEEIYLHGYDTVSEVRQAL
CHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
ARYFDFYNRRRPHSTLDGQTPDTAYFNQPLLAAAA
HHHHHHHHCCCCCCCCCCCCCCCHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]