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The map label for this gene is lpxH [H]

Identifier: 71906553

GI number: 71906553

Start: 990395

End: 991123

Strand: Reverse

Name: lpxH [H]

Synonym: Daro_0914

Alternate gene names: 71906553

Gene position: 991123-990395 (Counterclockwise)

Preceding gene: 71906554

Following gene: 71906552

Centisome position: 22.02

GC content: 60.77

Gene sequence:

>729_bases
TTGATCCTCTTCATCTCCGATCTGCATCTGTCGCCCCGGTCACCCGGGGCGACTGCTTTGTTCCTCCGCTTTTTGTCGGG
CCGCGCCCGCCAGGCCGAGGCTTTGTACATCCTCGGCGACCTGTTCGAGGTCTGGGTCGGCGACGACATTGACGATCCTT
ATCACAACAAAATCACCGCGGCCTTGCGGGCTGCCGCCGATGCCGGCCTGAAAATTTTCGTCATGCACGGCAACCGTGAT
TTCGCGCTCGGCGAGCAATTCGCAACGGCGGCCGGCATCAAACTCCTGTCCGACCCGTTCGACCTGACGCTACCTGAGTG
GTCTTTCGTCCTCTCGCACGGCGATGCACTGTGCCTAGATGATCATGCCTACATGACTTATCGAGCCAAGGTGCGTAACC
CGGCGTGGATGGAAAAAATGCGCGCCAAGCCACGCTTCCTGCGCAGCCTGCTCGGCCGCTACATCCGCTGGCGCAGCGGT
CGCCGAAAACGTGACCACAGCTACGTTTATGCCGACCTTCAACCAGCAGCGACGGACGATTTTCTGCGCGACCACGGCTA
CTGCACCTTCATTCACGGTCACACGCACCGACCGGCCAAGCACGACCACATTGTCGACGGCATCCATGTCGAACGCTGGG
TGCTGTCCGACTGGCACGAAGATCGCGGCGAGTGCCTGGCCTGGGATGGCGAAGCGCTGAAGCGTGAAGCCATCCTCCCT
GAAAACTGA

Upstream 100 bases:

>100_bases
TGGACGTCGTCGACAAGATTCGCGCCGTCAAGACCGGCAACAAGGGCTTCCATCAGGACGTTCCGGCTGAAGATGTGATC
ATCGAGAAGGCCGAGATCGT

Downstream 100 bases:

>100_bases
GCAAACCGCCTTGGCCACTGCTGCAAACGCTTTGAACGTCCTGCGCGACGTCTTCGGCTACCCCGCCTTCCGTGGCGAAC
AGGCGGAGATTATCGGCCAC

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MILFISDLHLSPRSPGATALFLRFLSGRARQAEALYILGDLFEVWVGDDIDDPYHNKITAALRAAADAGLKIFVMHGNRD
FALGEQFATAAGIKLLSDPFDLTLPEWSFVLSHGDALCLDDHAYMTYRAKVRNPAWMEKMRAKPRFLRSLLGRYIRWRSG
RRKRDHSYVYADLQPAATDDFLRDHGYCTFIHGHTHRPAKHDHIVDGIHVERWVLSDWHEDRGECLAWDGEALKREAILP
EN

Sequences:

>Translated_242_residues
MILFISDLHLSPRSPGATALFLRFLSGRARQAEALYILGDLFEVWVGDDIDDPYHNKITAALRAAADAGLKIFVMHGNRD
FALGEQFATAAGIKLLSDPFDLTLPEWSFVLSHGDALCLDDHAYMTYRAKVRNPAWMEKMRAKPRFLRSLLGRYIRWRSG
RRKRDHSYVYADLQPAATDDFLRDHGYCTFIHGHTHRPAKHDHIVDGIHVERWVLSDWHEDRGECLAWDGEALKREAILP
EN
>Mature_242_residues
MILFISDLHLSPRSPGATALFLRFLSGRARQAEALYILGDLFEVWVGDDIDDPYHNKITAALRAAADAGLKIFVMHGNRD
FALGEQFATAAGIKLLSDPFDLTLPEWSFVLSHGDALCLDDHAYMTYRAKVRNPAWMEKMRAKPRFLRSLLGRYIRWRSG
RRKRDHSYVYADLQPAATDDFLRDHGYCTFIHGHTHRPAKHDHIVDGIHVERWVLSDWHEDRGECLAWDGEALKREAILP
EN

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=220, Percent_Identity=43.6363636363636, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 27765; Mature: 27765

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILFISDLHLSPRSPGATALFLRFLSGRARQAEALYILGDLFEVWVGDDIDDPYHNKITA
CEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHH
ALRAAADAGLKIFVMHGNRDFALGEQFATAAGIKLLSDPFDLTLPEWSFVLSHGDALCLD
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCHHEECCCCCCCCCCHHEEECCCCEEEEE
DHAYMTYRAKVRNPAWMEKMRAKPRFLRSLLGRYIRWRSGRRKRDHSYVYADLQPAATDD
CCEEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHH
FLRDHGYCTFIHGHTHRPAKHDHIVDGIHVERWVLSDWHEDRGECLAWDGEALKREAILP
HHHHCCEEEEEECCCCCCCCCCCCCCCEEHHHHHHHCCCCCCCCEEEECCHHHHHCCCCC
EN
CC
>Mature Secondary Structure
MILFISDLHLSPRSPGATALFLRFLSGRARQAEALYILGDLFEVWVGDDIDDPYHNKITA
CEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHH
ALRAAADAGLKIFVMHGNRDFALGEQFATAAGIKLLSDPFDLTLPEWSFVLSHGDALCLD
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCHHEECCCCCCCCCCHHEEECCCCEEEEE
DHAYMTYRAKVRNPAWMEKMRAKPRFLRSLLGRYIRWRSGRRKRDHSYVYADLQPAATDD
CCEEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHH
FLRDHGYCTFIHGHTHRPAKHDHIVDGIHVERWVLSDWHEDRGECLAWDGEALKREAILP
HHHHCCEEEEEECCCCCCCCCCCCCCCEEHHHHHHHCCCCCCCCEEEECCHHHHHCCCCC
EN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA