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The map label for this gene is recQ [H]

Identifier: 71906552

GI number: 71906552

Start: 988567

End: 990420

Strand: Reverse

Name: recQ [H]

Synonym: Daro_0913

Alternate gene names: 71906552

Gene position: 990420-988567 (Counterclockwise)

Preceding gene: 71906553

Following gene: 71906551

Centisome position: 22.0

GC content: 63.92

Gene sequence:

>1854_bases
GTGAAGCCATCCTCCCTGAAAACTGAGCAAACCGCCTTGGCCACTGCTGCAAACGCTTTGAACGTCCTGCGCGACGTCTT
CGGCTACCCCGCCTTCCGTGGCGAACAGGCGGAGATTATCGGCCACGTCGCCAGTGGTGGCGATGCACTGGTGCTGATGC
CGACCGGCGGCGGCAAGAGCCTGTGTTACCAGATTCCCGCGCTGCTCCGCCCCGGCTGTGCCGTCGTCGTTTCGCCGCTG
ATCGCGCTGATGCAGGATCAGGTCGATGCGATGATCCAGCTTGGCGTCAAGGCCGCCTGCCTGAATTCGACCCTCGACTG
GCGCGAGGCCCAGGCGGTTGAGCAGGCCATCTTCAGCGGCAATCTCGACCTCGTCTATATCGCCCCCGAACGCCTGCTGC
TCGACCGCACGCTGGCCATGCTCGATTCCCTGTCCGAAGCCGGCAAGCTGGCGCTGTTCGCCATTGACGAAGCCCATTGC
GTCTCGCAATGGGGCCACGATTTCCGGCCGGAATACCTGCAACTGTCGGCGCTGCACGAGCGTTATCCGGCCGTACCACG
CATCGCCCTGACCGCCACCGCCGACCAGGCGACGCGCAACGAGATCCTGCAGCGGCTGGGCCTTGGTGAAGCGCGCGTTT
TCCTGTCCAGCTTCGACCGCCCGAACATTCGCTACACGGTGGTCGAGAAGGACAACGCCAAGAAGCAACTGCTCACTTTC
CTGACCGGCCGCAAGGGCCAGGCCGGTATCGTCTATTGCCTGTCGCGCAAGAAGGTCGAGGAAACGGCCGAATGGCTGTC
GACCCAAGGCTACCCGGCTCTGCCTTATCACGCTGGCCTGCCGGCGCCCGAACGCGCCGCCAACCAACGCCGCTTCCTGC
GCGAGGAAGGCCTGATCATGTGCGCCACGATCGCTTTCGGCATGGGCATCGACAAGCCGGATGTCCGCTTCGTCGCCCAC
CTCGATTTGCCGAAGAGCATCGAAGCCTATTACCAGGAAACCGGTCGTGCCGGCCGCGATGGCGAACCATCGGAGGCCTG
GATGACCTACGGCATGCAGGACGTCGCGCTGCAGCACGCGCGGATCGCCGAATCAGGCGCCGCCGAGGGCCAGAAGATCC
TCGAATCGCAGCGCCTGACTGCCCTGCTCTCTTACTGCGAAGCGCCGCGCTGTCGGCGCCAGGTGCTGCTCAATTACTTC
GGCGAAGAGCGCGAGCCCTGCGGCAACTGCGACGTATGCACCGAACCGCCGGAATTGTGGGATGGCACGCAGGCCGCGCA
AAAAGCGCTGTCAGCCATTTTCCGTACCGGCATGCGCTTCGGTGTCACCCACCTGACCGACATCCTGCGCGGCAAGGCGA
CGGACAAGGTCAAGCAGTGGAATCATGACCAGTTGCCGACCTTCGGCGTCGGCGGCGATCTCGACGACCACGCCTGGAAA
AGCGTTTTCCGGCAACTGGCCGCAGCGGGACTGGTCCATGTCGACATGGCCGAGCATGGCGCGCTGCAACTGACTGAAAC
GGCGCGCGAAGTGCTCAAGGGACAACGCACAGTGCAACTGCGCCGCCCGGTCAAACGCAAATCGACACCCTCCCGGTCGT
CGAGCAGCACGGTCGTCAGCGATCTGTCGCCGGCCGATGACGCGCTGTTCCAGCTGCTGCGCAAATGGCGGGCCGATACG
GCCAGAGAGCAGGCAGTACCGGCCTATGTCATCCTGCACGACAAGACCCTGCGCGAACTGGCCGAGGTCCGCCCGGTCAG
TCATGGCTTGCTGGCCGGCATTACCGGCATGGGCAGCGCCAAGATCGAACATTACGGGGCAGAATTGCTTGAATTGATTC
GTAACGAGGGCTGA

Upstream 100 bases:

>100_bases
GACCACATTGTCGACGGCATCCATGTCGAACGCTGGGTGCTGTCCGACTGGCACGAAGATCGCGGCGAGTGCCTGGCCTG
GGATGGCGAAGCGCTGAAGC

Downstream 100 bases:

>100_bases
CATGGAACAACGCGACAAGCTCAACGCCACGCTGGCCGCCATTGTGATCGCGGCGCTGGTCGTGTCGGGTATTGCCCCCT
ACGAGCGGCTGACCTGGGTC

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MKPSSLKTEQTALATAANALNVLRDVFGYPAFRGEQAEIIGHVASGGDALVLMPTGGGKSLCYQIPALLRPGCAVVVSPL
IALMQDQVDAMIQLGVKAACLNSTLDWREAQAVEQAIFSGNLDLVYIAPERLLLDRTLAMLDSLSEAGKLALFAIDEAHC
VSQWGHDFRPEYLQLSALHERYPAVPRIALTATADQATRNEILQRLGLGEARVFLSSFDRPNIRYTVVEKDNAKKQLLTF
LTGRKGQAGIVYCLSRKKVEETAEWLSTQGYPALPYHAGLPAPERAANQRRFLREEGLIMCATIAFGMGIDKPDVRFVAH
LDLPKSIEAYYQETGRAGRDGEPSEAWMTYGMQDVALQHARIAESGAAEGQKILESQRLTALLSYCEAPRCRRQVLLNYF
GEEREPCGNCDVCTEPPELWDGTQAAQKALSAIFRTGMRFGVTHLTDILRGKATDKVKQWNHDQLPTFGVGGDLDDHAWK
SVFRQLAAAGLVHVDMAEHGALQLTETAREVLKGQRTVQLRRPVKRKSTPSRSSSSTVVSDLSPADDALFQLLRKWRADT
AREQAVPAYVILHDKTLRELAEVRPVSHGLLAGITGMGSAKIEHYGAELLELIRNEG

Sequences:

>Translated_617_residues
MKPSSLKTEQTALATAANALNVLRDVFGYPAFRGEQAEIIGHVASGGDALVLMPTGGGKSLCYQIPALLRPGCAVVVSPL
IALMQDQVDAMIQLGVKAACLNSTLDWREAQAVEQAIFSGNLDLVYIAPERLLLDRTLAMLDSLSEAGKLALFAIDEAHC
VSQWGHDFRPEYLQLSALHERYPAVPRIALTATADQATRNEILQRLGLGEARVFLSSFDRPNIRYTVVEKDNAKKQLLTF
LTGRKGQAGIVYCLSRKKVEETAEWLSTQGYPALPYHAGLPAPERAANQRRFLREEGLIMCATIAFGMGIDKPDVRFVAH
LDLPKSIEAYYQETGRAGRDGEPSEAWMTYGMQDVALQHARIAESGAAEGQKILESQRLTALLSYCEAPRCRRQVLLNYF
GEEREPCGNCDVCTEPPELWDGTQAAQKALSAIFRTGMRFGVTHLTDILRGKATDKVKQWNHDQLPTFGVGGDLDDHAWK
SVFRQLAAAGLVHVDMAEHGALQLTETAREVLKGQRTVQLRRPVKRKSTPSRSSSSTVVSDLSPADDALFQLLRKWRADT
AREQAVPAYVILHDKTLRELAEVRPVSHGLLAGITGMGSAKIEHYGAELLELIRNEG
>Mature_617_residues
MKPSSLKTEQTALATAANALNVLRDVFGYPAFRGEQAEIIGHVASGGDALVLMPTGGGKSLCYQIPALLRPGCAVVVSPL
IALMQDQVDAMIQLGVKAACLNSTLDWREAQAVEQAIFSGNLDLVYIAPERLLLDRTLAMLDSLSEAGKLALFAIDEAHC
VSQWGHDFRPEYLQLSALHERYPAVPRIALTATADQATRNEILQRLGLGEARVFLSSFDRPNIRYTVVEKDNAKKQLLTF
LTGRKGQAGIVYCLSRKKVEETAEWLSTQGYPALPYHAGLPAPERAANQRRFLREEGLIMCATIAFGMGIDKPDVRFVAH
LDLPKSIEAYYQETGRAGRDGEPSEAWMTYGMQDVALQHARIAESGAAEGQKILESQRLTALLSYCEAPRCRRQVLLNYF
GEEREPCGNCDVCTEPPELWDGTQAAQKALSAIFRTGMRFGVTHLTDILRGKATDKVKQWNHDQLPTFGVGGDLDDHAWK
SVFRQLAAAGLVHVDMAEHGALQLTETAREVLKGQRTVQLRRPVKRKSTPSRSSSSTVVSDLSPADDALFQLLRKWRADT
AREQAVPAYVILHDKTLRELAEVRPVSHGLLAGITGMGSAKIEHYGAELLELIRNEG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=639, Percent_Identity=34.1158059467919, Blast_Score=338, Evalue=7e-93,
Organism=Homo sapiens, GI14591902, Length=410, Percent_Identity=38.0487804878049, Blast_Score=290, Evalue=3e-78,
Organism=Homo sapiens, GI14591904, Length=410, Percent_Identity=38.0487804878049, Blast_Score=290, Evalue=3e-78,
Organism=Homo sapiens, GI148612816, Length=420, Percent_Identity=38.5714285714286, Blast_Score=270, Evalue=4e-72,
Organism=Homo sapiens, GI110735439, Length=501, Percent_Identity=33.3333333333333, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI51242943, Length=390, Percent_Identity=38.974358974359, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI51242947, Length=390, Percent_Identity=38.974358974359, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI169218196, Length=501, Percent_Identity=33.3333333333333, Blast_Score=256, Evalue=5e-68,
Organism=Homo sapiens, GI284005309, Length=370, Percent_Identity=36.7567567567568, Blast_Score=206, Evalue=7e-53,
Organism=Escherichia coli, GI48994977, Length=604, Percent_Identity=48.1788079470199, Blast_Score=556, Evalue=1e-159,
Organism=Escherichia coli, GI87082221, Length=357, Percent_Identity=25.2100840336134, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=645, Percent_Identity=34.1085271317829, Blast_Score=346, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI71987997, Length=437, Percent_Identity=38.4439359267735, Blast_Score=295, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI71987993, Length=437, Percent_Identity=38.4439359267735, Blast_Score=295, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI32564293, Length=673, Percent_Identity=30.3120356612184, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17552866, Length=457, Percent_Identity=35.8862144420131, Blast_Score=264, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI115533224, Length=331, Percent_Identity=25.0755287009063, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323844, Length=547, Percent_Identity=35.6489945155393, Blast_Score=341, Evalue=2e-94,
Organism=Drosophila melanogaster, GI24646066, Length=625, Percent_Identity=34.88, Blast_Score=360, Evalue=2e-99,
Organism=Drosophila melanogaster, GI24664226, Length=459, Percent_Identity=37.9084967320261, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24664230, Length=459, Percent_Identity=37.9084967320261, Blast_Score=280, Evalue=3e-75,
Organism=Drosophila melanogaster, GI62472181, Length=459, Percent_Identity=37.9084967320261, Blast_Score=280, Evalue=3e-75,
Organism=Drosophila melanogaster, GI21358123, Length=352, Percent_Identity=36.6477272727273, Blast_Score=216, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 67835; Mature: 67835

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSSLKTEQTALATAANALNVLRDVFGYPAFRGEQAEIIGHVASGGDALVLMPTGGGKS
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEECCCCEEEEEECCCCCH
LCYQIPALLRPGCAVVVSPLIALMQDQVDAMIQLGVKAACLNSTLDWREAQAVEQAIFSG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHCC
NLDLVYIAPERLLLDRTLAMLDSLSEAGKLALFAIDEAHCVSQWGHDFRPEYLQLSALHE
CCCEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCHHHHHHHHHHH
RYPAVPRIALTATADQATRNEILQRLGLGEARVFLSSFDRPNIRYTVVEKDNAKKQLLTF
HCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEECCCHHHHHHHH
LTGRKGQAGIVYCLSRKKVEETAEWLSTQGYPALPYHAGLPAPERAANQRRFLREEGLIM
HHCCCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
CATIAFGMGIDKPDVRFVAHLDLPKSIEAYYQETGRAGRDGEPSEAWMTYGMQDVALQHA
EEHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHH
RIAESGAAEGQKILESQRLTALLSYCEAPRCRRQVLLNYFGEEREPCGNCDVCTEPPELW
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHC
DGTQAAQKALSAIFRTGMRFGVTHLTDILRGKATDKVKQWNHDQLPTFGVGGDLDDHAWK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHH
SVFRQLAAAGLVHVDMAEHGALQLTETAREVLKGQRTVQLRRPVKRKSTPSRSSSSTVVS
HHHHHHHHCCEEEEEHHCCCCEEHHHHHHHHHCCCHHHHHHCCHHHCCCCCCCCCCCHHH
DLSPADDALFQLLRKWRADTAREQAVPAYVILHDKTLRELAEVRPVSHGLLAGITGMGSA
CCCCCHHHHHHHHHHHHCCHHHHHCCCEEEEEECHHHHHHHHHCCCHHHHHHHHCCCCCH
KIEHYGAELLELIRNEG
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPSSLKTEQTALATAANALNVLRDVFGYPAFRGEQAEIIGHVASGGDALVLMPTGGGKS
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEECCCCEEEEEECCCCCH
LCYQIPALLRPGCAVVVSPLIALMQDQVDAMIQLGVKAACLNSTLDWREAQAVEQAIFSG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHCC
NLDLVYIAPERLLLDRTLAMLDSLSEAGKLALFAIDEAHCVSQWGHDFRPEYLQLSALHE
CCCEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCHHHHHHHHHHH
RYPAVPRIALTATADQATRNEILQRLGLGEARVFLSSFDRPNIRYTVVEKDNAKKQLLTF
HCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEECCCHHHHHHHH
LTGRKGQAGIVYCLSRKKVEETAEWLSTQGYPALPYHAGLPAPERAANQRRFLREEGLIM
HHCCCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
CATIAFGMGIDKPDVRFVAHLDLPKSIEAYYQETGRAGRDGEPSEAWMTYGMQDVALQHA
EEHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHH
RIAESGAAEGQKILESQRLTALLSYCEAPRCRRQVLLNYFGEEREPCGNCDVCTEPPELW
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHC
DGTQAAQKALSAIFRTGMRFGVTHLTDILRGKATDKVKQWNHDQLPTFGVGGDLDDHAWK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHH
SVFRQLAAAGLVHVDMAEHGALQLTETAREVLKGQRTVQLRRPVKRKSTPSRSSSSTVVS
HHHHHHHHCCEEEEEHHCCCCEEHHHHHHHHHCCCHHHHHHCCHHHCCCCCCCCCCCHHH
DLSPADDALFQLLRKWRADTAREQAVPAYVILHDKTLRELAEVRPVSHGLLAGITGMGSA
CCCCCHHHHHHHHHHHHCCHHHHHCCCEEEEEECHHHHHHHHHCCCHHHHHHHHCCCCCH
KIEHYGAELLELIRNEG
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]