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The map label for this gene is mmgC [H]

Identifier: 71906179

GI number: 71906179

Start: 596769

End: 597944

Strand: Reverse

Name: mmgC [H]

Synonym: Daro_0539

Alternate gene names: 71906179

Gene position: 597944-596769 (Counterclockwise)

Preceding gene: 71906180

Following gene: 71906178

Centisome position: 13.28

GC content: 63.18

Gene sequence:

>1176_bases
ATGGCCAAAGCCAGTTTCAACTGGGAAGACCCGCTGCTGCTTGATTCGCAACTCGCCGCCGATGAGCGTCAGGTCCGCAA
TGCCGCACGAAGCTTTGCGCAAAAGGCACTGGCCCCGCGCATCCGCGACGCTTTCCGCAACGAGACGACCGATCCGGCCA
TCTTCCGCGAAATGGGCGACATGGGCCTGCTCGGCCCGACCCTGCCACCACAATACGGCGGCGCCGGCCTCAACTACGTT
TCCTACGGCCTGATCGCCCGCGAGATCGAGCGCGTCGATTCGGCCTACCGGACGCTGCTCAGCGTGCAATCCTCGCTGGT
CATGCTGCCGATTTATGCTTTTGGCAGCGAAGAGCAGAAGCAGAAGTACCTGCCGAAACTGGGCAAGGGCGAATGGATCG
GCTGCTTCGGCCTGACCGAGCCGAATTCCGGTTCCGACCCCGGCAGCCTGGCCACCCGCGCCCGCACCGTGCCCGGCGGC
TGGAAGCTGTCCGGCAGCAAGAACTGGATTTCCAGTGCGCCGATCGCTGACGTTTTTGTCGTCTGGGCCAAGGACGACGA
TGGCGTGATTCGCGGCTTCATTCTCGACAAGGGCATGCCCGGGTTGTCGGCACCGGTCATCCACGGCAAGGTTGGCATGC
GCGCGGCGATCACCGGCGAAATCGTCATGGACGAGGTCTTCGTACCAAACGAGAACCTGCTGCCCGGCGTCAGCGGGCTG
AAGGGGCCATTCACCTGCCTGAATTCCGCCCGCTACGGCATCGCCTGGGGCGCGCTGGGTGCCGCCGAGGCCTGCTGGCA
TACGGCCCGCCAATACACGCTGGATCGCAAACAATTCGACAAGCCGCTGGCTGCCAACCAGCTGATCCAGAAAAAACTGG
CCGACATGCAGACCGAAATCACGCTCGGCATCCAGGGCGCGCTACGCCTCGGCCGCATGATGGACGACGGCAGTGCAACA
CCGGAAATCGTCTCGATGATGAAGCGCAACAGTTGCGGCAAGGCCCTCGACATCGCCCGCACCGCGCGCGACATGCTTGG
CGGCAACGGCATCTCCGACGATTTCGGCGTTATCCGGCACTTAGTGAACCTGGAAGTGGTCAATACCTACGAAGGGACGC
ACGACGTGCACGCCCTGATCCTTGGCCGGGCCCAAACCGGGATTTCGGCTTTCTAG

Upstream 100 bases:

>100_bases
GGTGGTACTCGGCGACGGCCACGTCCGAGGCTAAGCCGCTTCCGTCGACTCAACACAAGCATCCCCGCTCCGGCGGGGAT
GCGCTTTTCGGAGAAACCAC

Downstream 100 bases:

>100_bases
GCATCCTCGGAGGCTCCCCAATGCAAACTCGACCGAACCAGACCTATCAGGCCATCGTGGCCGCCCCCGGTTTCTGCCTG
GGGGTGCAGTGTGACGATGA

Product: Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region:Acyl-CoA dehydrogenase, N-terminal

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MAKASFNWEDPLLLDSQLAADERQVRNAARSFAQKALAPRIRDAFRNETTDPAIFREMGDMGLLGPTLPPQYGGAGLNYV
SYGLIAREIERVDSAYRTLLSVQSSLVMLPIYAFGSEEQKQKYLPKLGKGEWIGCFGLTEPNSGSDPGSLATRARTVPGG
WKLSGSKNWISSAPIADVFVVWAKDDDGVIRGFILDKGMPGLSAPVIHGKVGMRAAITGEIVMDEVFVPNENLLPGVSGL
KGPFTCLNSARYGIAWGALGAAEACWHTARQYTLDRKQFDKPLAANQLIQKKLADMQTEITLGIQGALRLGRMMDDGSAT
PEIVSMMKRNSCGKALDIARTARDMLGGNGISDDFGVIRHLVNLEVVNTYEGTHDVHALILGRAQTGISAF

Sequences:

>Translated_391_residues
MAKASFNWEDPLLLDSQLAADERQVRNAARSFAQKALAPRIRDAFRNETTDPAIFREMGDMGLLGPTLPPQYGGAGLNYV
SYGLIAREIERVDSAYRTLLSVQSSLVMLPIYAFGSEEQKQKYLPKLGKGEWIGCFGLTEPNSGSDPGSLATRARTVPGG
WKLSGSKNWISSAPIADVFVVWAKDDDGVIRGFILDKGMPGLSAPVIHGKVGMRAAITGEIVMDEVFVPNENLLPGVSGL
KGPFTCLNSARYGIAWGALGAAEACWHTARQYTLDRKQFDKPLAANQLIQKKLADMQTEITLGIQGALRLGRMMDDGSAT
PEIVSMMKRNSCGKALDIARTARDMLGGNGISDDFGVIRHLVNLEVVNTYEGTHDVHALILGRAQTGISAF
>Mature_390_residues
AKASFNWEDPLLLDSQLAADERQVRNAARSFAQKALAPRIRDAFRNETTDPAIFREMGDMGLLGPTLPPQYGGAGLNYVS
YGLIAREIERVDSAYRTLLSVQSSLVMLPIYAFGSEEQKQKYLPKLGKGEWIGCFGLTEPNSGSDPGSLATRARTVPGGW
KLSGSKNWISSAPIADVFVVWAKDDDGVIRGFILDKGMPGLSAPVIHGKVGMRAAITGEIVMDEVFVPNENLLPGVSGLK
GPFTCLNSARYGIAWGALGAAEACWHTARQYTLDRKQFDKPLAANQLIQKKLADMQTEITLGIQGALRLGRMMDDGSATP
EIVSMMKRNSCGKALDIARTARDMLGGNGISDDFGVIRHLVNLEVVNTYEGTHDVHALILGRAQTGISAF

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=396, Percent_Identity=64.6464646464647, Blast_Score=529, Evalue=1e-150,
Organism=Homo sapiens, GI7669494, Length=372, Percent_Identity=63.4408602150538, Blast_Score=493, Evalue=1e-140,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=33.7765957446808, Blast_Score=201, Evalue=9e-52,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=32.258064516129, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI226958414, Length=345, Percent_Identity=33.3333333333333, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI4501859, Length=362, Percent_Identity=30.3867403314917, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=29.9479166666667, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=29.9479166666667, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI21361497, Length=336, Percent_Identity=31.547619047619, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI187960098, Length=389, Percent_Identity=27.2493573264781, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI4557231, Length=389, Percent_Identity=27.2493573264781, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=29.0666666666667, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI4501857, Length=372, Percent_Identity=27.4193548387097, Blast_Score=125, Evalue=7e-29,
Organism=Escherichia coli, GI1786223, Length=347, Percent_Identity=25.9365994236311, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87081958, Length=356, Percent_Identity=25.2808988764045, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17534353, Length=393, Percent_Identity=59.7964376590331, Blast_Score=490, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=32.620320855615, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17508101, Length=366, Percent_Identity=30.6010928961749, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17569725, Length=387, Percent_Identity=28.4237726098191, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=27.1232876712329, Blast_Score=147, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI71985184, Length=357, Percent_Identity=29.9719887955182, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=27.1276595744681, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71982178, Length=268, Percent_Identity=32.4626865671642, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=292, Percent_Identity=31.5068493150685, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71990804, Length=277, Percent_Identity=31.4079422382672, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=25.5936675461741, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=26.8617021276596, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=30.7359307359307, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17551932, Length=351, Percent_Identity=23.9316239316239, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=342, Percent_Identity=23.6842105263158, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920834, Length=394, Percent_Identity=60.9137055837564, Blast_Score=493, Evalue=1e-139,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=32.258064516129, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=30.6451612903226, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24666513, Length=365, Percent_Identity=31.5068493150685, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=30.9333333333333, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=29.1005291005291, Blast_Score=158, Evalue=5e-39,
Organism=Drosophila melanogaster, GI281363737, Length=387, Percent_Identity=29.1989664082687, Blast_Score=151, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 42303; Mature: 42172

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKASFNWEDPLLLDSQLAADERQVRNAARSFAQKALAPRIRDAFRNETTDPAIFREMGD
CCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
MGLLGPTLPPQYGGAGLNYVSYGLIAREIERVDSAYRTLLSVQSSLVMLPIYAFGSEEQK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHH
QKYLPKLGKGEWIGCFGLTEPNSGSDPGSLATRARTVPGGWKLSGSKNWISSAPIADVFV
HHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHEECCCCEEECCCCCCCCCCCCEEEEE
VWAKDDDGVIRGFILDKGMPGLSAPVIHGKVGMRAAITGEIVMDEVFVPNENLLPGVSGL
EEECCCCCEEEEEEECCCCCCCCCCEEECCCCCEEEEEHHHHHHEEECCCCCCCCCCCCC
KGPFTCLNSARYGIAWGALGAAEACWHTARQYTLDRKQFDKPLAANQLIQKKLADMQTEI
CCHHHHHHCCCCCEEHHCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHH
TLGIQGALRLGRMMDDGSATPEIVSMMKRNSCGKALDIARTARDMLGGNGISDDFGVIRH
EECHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
LVNLEVVNTYEGTHDVHALILGRAQTGISAF
HHHHEEEECCCCCHHEEHHEEECCCCCCCCC
>Mature Secondary Structure 
AKASFNWEDPLLLDSQLAADERQVRNAARSFAQKALAPRIRDAFRNETTDPAIFREMGD
CCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
MGLLGPTLPPQYGGAGLNYVSYGLIAREIERVDSAYRTLLSVQSSLVMLPIYAFGSEEQK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHH
QKYLPKLGKGEWIGCFGLTEPNSGSDPGSLATRARTVPGGWKLSGSKNWISSAPIADVFV
HHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHEECCCCEEECCCCCCCCCCCCEEEEE
VWAKDDDGVIRGFILDKGMPGLSAPVIHGKVGMRAAITGEIVMDEVFVPNENLLPGVSGL
EEECCCCCEEEEEEECCCCCCCCCCEEECCCCCEEEEEHHHHHHEEECCCCCCCCCCCCC
KGPFTCLNSARYGIAWGALGAAEACWHTARQYTLDRKQFDKPLAANQLIQKKLADMQTEI
CCHHHHHHCCCCCEEHHCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHH
TLGIQGALRLGRMMDDGSATPEIVSMMKRNSCGKALDIARTARDMLGGNGISDDFGVIRH
EECHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
LVNLEVVNTYEGTHDVHALILGRAQTGISAF
HHHHEEEECCCCCHHEEHHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]