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The map label for this gene is cysS [H]

Identifier: 71893989

GI number: 71893989

Start: 840556

End: 841761

Strand: Reverse

Name: cysS [H]

Synonym: MHJ_0641

Alternate gene names: 71893989

Gene position: 841761-840556 (Counterclockwise)

Preceding gene: 71893990

Following gene: 71893988

Centisome position: 93.8

GC content: 25.87

Gene sequence:

>1206_bases
ATTAATAAAAAAAATTTAAATATCTATCTTTGCGGGCCAACAGTTTATAGCGATGTTCATATTGGAAATTTAAGAACTAT
AATTATTTTTGATGCTATTTTTGAATGTTTGAAAAACAAAGGTTTTTCGATAAATTTTTTACATAATATCACAGATATTG
ATGATAAAATTATTGAAAAAGCACAAGAATTAGGCATTTCTGAGGCTGAGCTAACAGAAAAATATACTAACGAATATTTT
AAAATTTTAGAAATTTTTAATATAAAAAAGCCAACAAAAATCGTTAAGGTGACCGAAAAAATAGAAAAAATTATAGAATA
TATAAAACTTTTAGAAAAAAAGGGATTTACATATTATAACAAAAACAATGACTTGGTTTTTGACATATTAAAAATTCCTA
ATTACGGAATAATTTCTGGTCAAAAAATAGAATCATTACTGGATAAAAATACTAAAAAAACAAAGTCAAAAAATGACTTT
GTTTTATGAAAAAAAACCCAAAAAGGCTTGTTTTTTAAGTCTTTGTTCGGTTTAGGCCGACCTGGTTGACATACTGAATG
TGCAGCACTTATCTATGATTATTTTCAAAAAAAATCACTTGATCTTCATGGTGGCGGGGTTGACTTAATTTTTCCTCATC
ACGAAAACGAAAATGCTCAACATTTTGCTCTAACGGGAAATCCAATTGCCGAAAACTGGTTTCGCTCTGGGTTTGTTAAT
TTAAATGGAAAAAAAATGGCCAAATCTCTGAATAATGTACTATTGGCAAAGAATTTTTCGCATAAATATAATCCAGATAT
TATTAGAAGTATTTTTTTGTCAATAAACCCAACAGTTCCAATCAATTTAACTGAAGAATTAATTAAAAATCATAAAAAAT
TAATCGAAAAATACCAAAAGATCTGTTTTGAGTGATATTTTGACAAAAAAAACGAAAAGACTGAAAAAGTTGAACAAGTG
CTTAATTTATTTATTGAGGGCAAATTCGCAAAAGCTAATTTTTTAATTATGGAATTAATAAAACAAAAAGAAAATTCAAC
TATAAGAAAAATTTTTCTAAATTTAAGATTTAATTTCACAAAAATGCGTTTGGACCCCGAAAGTCAGGAAAAAATCAAAA
ATTGAAACAAATTAATTATGGATAAAAACTATTCCGAGGCCGATAAAATCCGTGAAGAATTATGAAAAATATTTAAAAAT
TCATAA

Upstream 100 bases:

>100_bases
CATTTTTTTAGCAAGCATAATAAACTTTTTTGGGAAAAAGTAGCTGAAATTATTCCTAATTATAAGGAATTAATTAGAAA
ATTAAATGACTATGAACTTA

Downstream 100 bases:

>100_bases
TTTTTTCCATCTTCCTTTTGAAAGATTGAAAGTATGGTTAAATATATTTGTGGCAGAAATTCATTAGCCGACGCGATCAA
GAATGGGTTTATTTTTAAGG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MNKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKIIEKAQELGISEAELTEKYTNEYF
KILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFTYYNKNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSKNDF
VLWKKTQKGLFFKSLFGLGRPGWHTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSGFVN
LNGKKMAKSLNNVLLAKNFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQKICFEWYFDKKNEKTEKVEQV
LNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFTKMRLDPESQEKIKNWNKLIMDKNYSEADKIREELWKIFKN
S

Sequences:

>Translated_401_residues
MNKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKIIEKAQELGISEAELTEKYTNEYF
KILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFTYYNKNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSKNDF
VL*KKTQKGLFFKSLFGLGRPG*HTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSGFVN
LNGKKMAKSLNNVLLAKNFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQKICFE*YFDKKNEKTEKVEQV
LNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFTKMRLDPESQEKIKN*NKLIMDKNYSEADKIREEL*KIFKN
S
>Mature_401_residues
MNKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKIIEKAQELGISEAELTEKYTNEYF
KILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFTYYNKNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSKNDF
VL*KKTQKGLFFKSLFGLGRPG*HTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSGFVN
LNGKKMAKSLNNVLLAKNFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQKICFE*YFDKKNEKTEKVEQV
LNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFTKMRLDPESQEKIKN*NKLIMDKNYSEADKIREEL*KIFKN
S

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=274, Percent_Identity=35.7664233576642, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI303304987, Length=227, Percent_Identity=29.0748898678414, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI21269877, Length=227, Percent_Identity=29.0748898678414, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI62240992, Length=227, Percent_Identity=29.0748898678414, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI10835051, Length=224, Percent_Identity=29.0178571428571, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1786737, Length=306, Percent_Identity=33.9869281045752, Blast_Score=182, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17509795, Length=231, Percent_Identity=31.1688311688312, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17509797, Length=231, Percent_Identity=31.1688311688312, Blast_Score=101, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6324082, Length=220, Percent_Identity=31.8181818181818, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI19922218, Length=306, Percent_Identity=32.0261437908497, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI19922364, Length=255, Percent_Identity=28.2352941176471, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 46114; Mature: 46114

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKIIEK
CCCCCEEEEEECCCEECCEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
AQELGISEAELTEKYTNEYFKILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFTYYN
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
KNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSKNDFVLKKTQKGLFFKSLFGLGRP
CCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHCCCCCCEEEEHHHCCHHHHHHHCCCCC
GHTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSGFVNLN
CHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHCCCCCCC
GKKMAKSLNNVLLAKNFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQKIC
HHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FEYFDKKNEKTEKVEQVLNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFTKMR
HHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEEEE
LDPESQEKIKNNKLIMDKNYSEADKIREELKIFKNS
ECCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKIIEK
CCCCCEEEEEECCCEECCEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
AQELGISEAELTEKYTNEYFKILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFTYYN
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
KNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSKNDFVLKKTQKGLFFKSLFGLGRP
CCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHCCCCCCEEEEHHHCCHHHHHHHCCCCC
GHTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSGFVNLN
CHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHCCCCCCC
GKKMAKSLNNVLLAKNFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQKIC
HHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FEYFDKKNEKTEKVEQVLNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFTKMR
HHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEEEE
LDPESQEKIKNNKLIMDKNYSEADKIREELKIFKNS
ECCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA