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The map label for this gene is fba-1 [H]

Identifier: 71893923

GI number: 71893923

Start: 741897

End: 742718

Strand: Reverse

Name: fba-1 [H]

Synonym: MHJ_0574

Alternate gene names: 71893923

Gene position: 742718-741897 (Counterclockwise)

Preceding gene: 71893924

Following gene: 71893921

Centisome position: 82.76

GC content: 29.08

Gene sequence:

>822_bases
ATCGATCCAAAAGAAACATTTTCAAAACTAAATGCAGAGAATAAACCAATTTTTGCTTTTAATGTTATAAATTTAGAAAC
ACTTTTTGCTGTAATTAAAGCAGGTGAAATTTCTAAAAAACCCTTAATAATTCAGTTAAGTTTGGGAGGAATTAGATATT
CCCGTATTGAATTTCTAGCACCAATGATTGTTTCGGCGATTAAAAATTCACCAGGAAAATTTATTTTTCACCTTGATCAC
TGTGATGATTTAGAACTTTTTGAAAAATATCTTGAATTAGGTTTTAATTCTGCTATGTTTGATGGCTCAAAATTTGATGT
TGCTAAAAATATCGAAAAATCTTTAAAAGCAAAGGAACTTGCCAAGGAAAAAAATATTTTCCTTGAGTTAGAAATTGGCC
AAATCGGCGGGAAGGAAATTGGTCATCAAGCAGAAAATCAGCAAATTCTTGACCTAGAAATTATAAAAGATTTTTATAAA
AAAACTCAACCTGATCTTTTGGCAATTGCTTTTGGAACTGCTCATGGAATTTACAAGAAAAAGGCAAATCTTAACTGAGA
ATTAATCCAAAATTTCAAAAAAGCATATAGAATTCCGCTTGTTATGCATGGAACAAGTGGTCTTTCGATTCAAGAAATTC
AAAAAGGAATTAGTTGTGGAATTAACAAAATCAATATTTTTACAGACCTTTTAGTTAGTTTTTCCGAACAGGTGAAACTA
TATTTTCAGGAAAATCCAAATGCCTTTGATATTCGGAAAATTAATGAAAAAGGAATTGAAAAGATGACAGAAAAAATTCT
TTCTTATCTTAAAATAGCATAA

Upstream 100 bases:

>100_bases
TTGTCCGTGTTGGAAATAAAGGATATCAAATTATTATTGGAACCGATGTTGAATTTGTAGCTGATTATCTTAAAAAAATG
ATAGGAAAATAATGGTTTTT

Downstream 100 bases:

>100_bases
GAATCTAACATTTTATTTTTCTTCTCTGGTTTAAAAAAGCTTTAAATTCATAGACTATTTTGCAAATTCGCGGTAAATTT
GGCCAAAAATGATTGACATT

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MDPKETFSKLNAENKPIFAFNVINLETLFAVIKAGEISKKPLIIQLSLGGIRYSRIEFLAPMIVSAIKNSPGKFIFHLDH
CDDLELFEKYLELGFNSAMFDGSKFDVAKNIEKSLKAKELAKEKNIFLELEIGQIGGKEIGHQAENQQILDLEIIKDFYK
KTQPDLLAIAFGTAHGIYKKKANLNWELIQNFKKAYRIPLVMHGTSGLSIQEIQKGISCGINKINIFTDLLVSFSEQVKL
YFQENPNAFDIRKINEKGIEKMTEKILSYLKIA

Sequences:

>Translated_273_residues
MDPKETFSKLNAENKPIFAFNVINLETLFAVIKAGEISKKPLIIQLSLGGIRYSRIEFLAPMIVSAIKNSPGKFIFHLDH
CDDLELFEKYLELGFNSAMFDGSKFDVAKNIEKSLKAKELAKEKNIFLELEIGQIGGKEIGHQAENQQILDLEIIKDFYK
KTQPDLLAIAFGTAHGIYKKKANLN*ELIQNFKKAYRIPLVMHGTSGLSIQEIQKGISCGINKINIFTDLLVSFSEQVKL
YFQENPNAFDIRKINEKGIEKMTEKILSYLKIA
>Mature_273_residues
MDPKETFSKLNAENKPIFAFNVINLETLFAVIKAGEISKKPLIIQLSLGGIRYSRIEFLAPMIVSAIKNSPGKFIFHLDH
CDDLELFEKYLELGFNSAMFDGSKFDVAKNIEKSLKAKELAKEKNIFLELEIGQIGGKEIGHQAENQQILDLEIIKDFYK
KTQPDLLAIAFGTAHGIYKKKANLN*ELIQNFKKAYRIPLVMHGTSGLSIQEIQKGISCGINKINIFTDLLVSFSEQVKL
YFQENPNAFDIRKINEKGIEKMTEKILSYLKIA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788072, Length=259, Percent_Identity=33.976833976834, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082041, Length=238, Percent_Identity=32.7731092436975, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789526, Length=266, Percent_Identity=28.9473684210526, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1789293, Length=311, Percent_Identity=26.3665594855305, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322790, Length=319, Percent_Identity=27.8996865203762, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30789; Mature: 30789

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPKETFSKLNAENKPIFAFNVINLETLFAVIKAGEISKKPLIIQLSLGGIRYSRIEFLA
CCHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCEEEEEECCCEEHHHHHHHH
PMIVSAIKNSPGKFIFHLDHCDDLELFEKYLELGFNSAMFDGSKFDVAKNIEKSLKAKEL
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AKEKNIFLELEIGQIGGKEIGHQAENQQILDLEIIKDFYKKTQPDLLAIAFGTAHGIYKK
HHHCCEEEEEEECCCCCHHHCCCCCCCEEEHHHHHHHHHHCCCCCEEEEEEHHHHHHHHH
KANLNELIQNFKKAYRIPLVMHGTSGLSIQEIQKGISCGINKINIFTDLLVSFSEQVKLY
CCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEE
FQENPNAFDIRKINEKGIEKMTEKILSYLKIA
EECCCCEEEEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDPKETFSKLNAENKPIFAFNVINLETLFAVIKAGEISKKPLIIQLSLGGIRYSRIEFLA
CCHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCEEEEEECCCEEHHHHHHHH
PMIVSAIKNSPGKFIFHLDHCDDLELFEKYLELGFNSAMFDGSKFDVAKNIEKSLKAKEL
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AKEKNIFLELEIGQIGGKEIGHQAENQQILDLEIIKDFYKKTQPDLLAIAFGTAHGIYKK
HHHCCEEEEEEECCCCCHHHCCCCCCCEEEHHHHHHHHHHCCCCCEEEEEEHHHHHHHHH
KANLNELIQNFKKAYRIPLVMHGTSGLSIQEIQKGISCGINKINIFTDLLVSFSEQVKLY
CCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEE
FQENPNAFDIRKINEKGIEKMTEKILSYLKIA
EECCCCEEEEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]