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The map label for this gene is ribD [H]

Identifier: 71892014

GI number: 71892014

Start: 271407

End: 272546

Strand: Direct

Name: ribD [H]

Synonym: BPEN_240

Alternate gene names: 71892014

Gene position: 271407-272546 (Clockwise)

Preceding gene: 71892013

Following gene: 71892015

Centisome position: 34.28

GC content: 36.58

Gene sequence:

>1140_bases
ATGACAGACAATATTATACTACATGATAAAAGATTTTTAACACGAGCACTTCAATTGGCATGGAAAGGACGATTTACTAC
GATGCCTAATCCTAATGTAGGATGTGTTATCGTTCGCAACAATAAAATTATAGGAGAGGGATATCACATACGAGCAGGAG
AAGCACATGCTGAAATACATGCGTTACGTATTGCTGGAAATTTAGCACAAGGAGCAACTGCTTATATCACTCTGGAACCA
TGTAGTCATTACGGACGTACTCCTCCTTGCACTACTGCATTAATTAATGCAGGAATTAAACGCGTTGTTGTAGCTATGTT
AGATCCTCATTTTTACGCAAGAGGACGTGGTTTGCATTTGCTGCAACAAGCAGGTATTGAAGTACAGCATAGTCTGATGT
TACCTGAAGCTGAATCAATAAATCGAGGATTTCTCAAACGTATACGTACCGGATTTCCATGGGTTAAATTAAAATTAGCT
GCATCTCTAGATGGTAGGACTGCTATGTCTTCTGGAGAAAGTAAATGGATTACATCTATTCAGGCGCGCCAAGATGTACC
ACGTTTCCGTGCAGAAAGTGATGTCATTCTTTCTACTGCTGGCACTGTTTTAGCAGATGATCCAAAATTAAATGTACGTT
GGGAATGCTTTTCAGACGAAATGAAACGTATTTATGCCAACAATCAAATTAGGCAACCACTAAGAGTCATTATTGATAGC
GCAAATAGAGTACTTCCAACACATCGTGTTATACGATATGAGGGAAAAATTCTACTCGTGCGTTTAAAAAAAGACCATCG
AAATTGGCCCTCATCAGTAGAACAACTATTATTATCATCAATTAATTGTCATGGCCATCATCGAATAAACTTAACAGAAT
TAATGCAACATCTTGGATATCGTGAAATTAATAATATTTGGGTAGAAGCAGGAGCTACTTTTTCAGGAGTATTATTAGAT
ATTGGATTGGTAGACGAACTTATTCTGTATCAAGCTATAAAATTTTTAGGATCTGACGCGCGGCCTTTATGTTTATTACC
AAATATCAAATGTCTGAATGACATTAAATCTTTTAAATTACTTGACATAAAAAATATAGGACCAGATCTTCGTTTAAGGT
TAATCCCAAAGGGTATGTAA

Upstream 100 bases:

>100_bases
CCAAAACAATAGCACTCTCGTAATATCGGATTTAAATTATTTTTTATTAATAAAATTGATCATTATAAAAATATATTTAG
TTTCACGATCTCATGATACT

Downstream 100 bases:

>100_bases
TATATTTTTATTAGTTATACTAATTATGCTATCTATGCTATAACATGTTTATTTGTAAATAAGAACAAGTAATGATTTTA
GTAGCCTGAATAATAAGGAT

Product: pyrimidine deaminase/reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MTDNIILHDKRFLTRALQLAWKGRFTTMPNPNVGCVIVRNNKIIGEGYHIRAGEAHAEIHALRIAGNLAQGATAYITLEP
CSHYGRTPPCTTALINAGIKRVVVAMLDPHFYARGRGLHLLQQAGIEVQHSLMLPEAESINRGFLKRIRTGFPWVKLKLA
ASLDGRTAMSSGESKWITSIQARQDVPRFRAESDVILSTAGTVLADDPKLNVRWECFSDEMKRIYANNQIRQPLRVIIDS
ANRVLPTHRVIRYEGKILLVRLKKDHRNWPSSVEQLLLSSINCHGHHRINLTELMQHLGYREINNIWVEAGATFSGVLLD
IGLVDELILYQAIKFLGSDARPLCLLPNIKCLNDIKSFKLLDIKNIGPDLRLRLIPKGM

Sequences:

>Translated_379_residues
MTDNIILHDKRFLTRALQLAWKGRFTTMPNPNVGCVIVRNNKIIGEGYHIRAGEAHAEIHALRIAGNLAQGATAYITLEP
CSHYGRTPPCTTALINAGIKRVVVAMLDPHFYARGRGLHLLQQAGIEVQHSLMLPEAESINRGFLKRIRTGFPWVKLKLA
ASLDGRTAMSSGESKWITSIQARQDVPRFRAESDVILSTAGTVLADDPKLNVRWECFSDEMKRIYANNQIRQPLRVIIDS
ANRVLPTHRVIRYEGKILLVRLKKDHRNWPSSVEQLLLSSINCHGHHRINLTELMQHLGYREINNIWVEAGATFSGVLLD
IGLVDELILYQAIKFLGSDARPLCLLPNIKCLNDIKSFKLLDIKNIGPDLRLRLIPKGM
>Mature_378_residues
TDNIILHDKRFLTRALQLAWKGRFTTMPNPNVGCVIVRNNKIIGEGYHIRAGEAHAEIHALRIAGNLAQGATAYITLEPC
SHYGRTPPCTTALINAGIKRVVVAMLDPHFYARGRGLHLLQQAGIEVQHSLMLPEAESINRGFLKRIRTGFPWVKLKLAA
SLDGRTAMSSGESKWITSIQARQDVPRFRAESDVILSTAGTVLADDPKLNVRWECFSDEMKRIYANNQIRQPLRVIIDSA
NRVLPTHRVIRYEGKILLVRLKKDHRNWPSSVEQLLLSSINCHGHHRINLTELMQHLGYREINNIWVEAGATFSGVLLDI
GLVDELILYQAIKFLGSDARPLCLLPNIKCLNDIKSFKLLDIKNIGPDLRLRLIPKGM

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=369, Percent_Identity=56.9105691056911, Blast_Score=452, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 42684; Mature: 42552

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNIILHDKRFLTRALQLAWKGRFTTMPNPNVGCVIVRNNKIIGEGYHIRAGEAHAEIH
CCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCEEEECCCCCCEEE
ALRIAGNLAQGATAYITLEPCSHYGRTPPCTTALINAGIKRVVVAMLDPHFYARGRGLHL
EEEEECCCCCCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHH
LQQAGIEVQHSLMLPEAESINRGFLKRIRTGFPWVKLKLAASLDGRTAMSSGESKWITSI
HHHCCCCEEEEEECCCHHHCCHHHHHHHHCCCCEEEEEEEECCCCCHHHCCCCCHHHHHH
QARQDVPRFRAESDVILSTAGTVLADDPKLNVRWECFSDEMKRIYANNQIRQPLRVIIDS
HHHHCCCHHCCCCCEEEEECCCEEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHHC
ANRVLPTHRVIRYEGKILLVRLKKDHRNWPSSVEQLLLSSINCHGHHRINLTELMQHLGY
CCCCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHCCH
REINNIWVEAGATFSGVLLDIGLVDELILYQAIKFLGSDARPLCLLPNIKCLNDIKSFKL
HHHCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHCCEEE
LDIKNIGPDLRLRLIPKGM
EEECCCCCCCEEEEECCCC
>Mature Secondary Structure 
TDNIILHDKRFLTRALQLAWKGRFTTMPNPNVGCVIVRNNKIIGEGYHIRAGEAHAEIH
CCCEEEECHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCEEEECCCCCCEEE
ALRIAGNLAQGATAYITLEPCSHYGRTPPCTTALINAGIKRVVVAMLDPHFYARGRGLHL
EEEEECCCCCCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHH
LQQAGIEVQHSLMLPEAESINRGFLKRIRTGFPWVKLKLAASLDGRTAMSSGESKWITSI
HHHCCCCEEEEEECCCHHHCCHHHHHHHHCCCCEEEEEEEECCCCCHHHCCCCCHHHHHH
QARQDVPRFRAESDVILSTAGTVLADDPKLNVRWECFSDEMKRIYANNQIRQPLRVIIDS
HHHHCCCHHCCCCCEEEEECCCEEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHHC
ANRVLPTHRVIRYEGKILLVRLKKDHRNWPSSVEQLLLSSINCHGHHRINLTELMQHLGY
CCCCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHCCH
REINNIWVEAGATFSGVLLDIGLVDELILYQAIKFLGSDARPLCLLPNIKCLNDIKSFKL
HHHCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHCCEEE
LDIKNIGPDLRLRLIPKGM
EEECCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]