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The map label for this gene is ribH

Identifier: 71892015

GI number: 71892015

Start: 272651

End: 273127

Strand: Direct

Name: ribH

Synonym: BPEN_241

Alternate gene names: 71892015

Gene position: 272651-273127 (Clockwise)

Preceding gene: 71892014

Following gene: 71892016

Centisome position: 34.44

GC content: 30.4

Gene sequence:

>477_bases
ATGAATATTATTGAAAGTGATACTATAGCAAATAAAGCTAAGATTGCTATCGCGGTTGTTCGATTTAATCGTTTCGTTAA
TAATAATTTACTTGAAGGAGCTTTAGATGTTTTAAAAAGAATTGGACACGTAAAAGATGAAAATATAACCATAATTTGGG
TTCCAGGCTCCTATGAATTACCATTAATCGCAAAAGCATTGGCTATTAGTCATAAGTATGATGGAATAATAGCTTTGGGT
ACAGTAATTCGTGGATTTACCATACATTTTGAATTTGTTGCAAAAGAATGTAGCTCTGGATTATCCAGAATTTCCATGGA
AAACACATTGCCTATTGGATTTGGATTACTTACTACGGATAATATTAGTCAAGCTATAGAACGTTCAGGTATTAAAGCTA
ATAACAAAGGATCAGAAGCTGCTTTGGCTGTTTTAGAAATGATTAATATACTAAAAATAATTAAAAATAGTTCTTAA

Upstream 100 bases:

>100_bases
TTTTTATTAGTTATACTAATTATGCTATCTATGCTATAACATGTTTATTTGTAAATAAGAACAAGTAATGATTTTAGTAG
CCTGAATAATAAGGATTATT

Downstream 100 bases:

>100_bases
TACATATAAATATATCAAAGGAATTACGTGAAAGCAATTAGTAGAAGGCGTGCTCGTGAATGTACATTGCAGGCATTGTA
TTCTTGGCAAGTATCTAAAA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MNIIESDTIANKAKIAIAVVRFNRFVNNNLLEGALDVLKRIGHVKDENITIIWVPGSYELPLIAKALAISHKYDGIIALG
TVIRGFTIHFEFVAKECSSGLSRISMENTLPIGFGLLTTDNISQAIERSGIKANNKGSEAALAVLEMINILKIIKNSS

Sequences:

>Translated_158_residues
MNIIESDTIANKAKIAIAVVRFNRFVNNNLLEGALDVLKRIGHVKDENITIIWVPGSYELPLIAKALAISHKYDGIIALG
TVIRGFTIHFEFVAKECSSGLSRISMENTLPIGFGLLTTDNISQAIERSGIKANNKGSEAALAVLEMINILKIIKNSS
>Mature_158_residues
MNIIESDTIANKAKIAIAVVRFNRFVNNNLLEGALDVLKRIGHVKDENITIIWVPGSYELPLIAKALAISHKYDGIIALG
TVIRGFTIHFEFVAKECSSGLSRISMENTLPIGFGLLTTDNISQAIERSGIKANNKGSEAALAVLEMINILKIIKNSS

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=155, Percent_Identity=61.9354838709677, Blast_Score=209, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6324429, Length=154, Percent_Identity=31.1688311688312, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_BLOPB (Q494E6)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277745.1
- HSSP:   Q9UUB1
- ProteinModelPortal:   Q494E6
- SMR:   Q494E6
- STRING:   Q494E6
- GeneID:   3562775
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_241
- eggNOG:   COG0054
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- ProtClustDB:   PRK00061
- BioCyc:   CBLO291272:BPEN_241-MONOMER
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 17190; Mature: 17190

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIESDTIANKAKIAIAVVRFNRFVNNNLLEGALDVLKRIGHVKDENITIIWVPGSYEL
CCCCCCCCCCCHHHHEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
PLIAKALAISHKYDGIIALGTVIRGFTIHFEFVAKECSSGLSRISMENTLPIGFGLLTTD
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
NISQAIERSGIKANNKGSEAALAVLEMINILKIIKNSS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIIESDTIANKAKIAIAVVRFNRFVNNNLLEGALDVLKRIGHVKDENITIIWVPGSYEL
CCCCCCCCCCCHHHHEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
PLIAKALAISHKYDGIIALGTVIRGFTIHFEFVAKECSSGLSRISMENTLPIGFGLLTTD
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
NISQAIERSGIKANNKGSEAALAVLEMINILKIIKNSS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA