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The map label for this gene is glpX [H]

Identifier: 68536539

GI number: 68536539

Start: 1711023

End: 1712120

Strand: Direct

Name: glpX [H]

Synonym: jk1453

Alternate gene names: 68536539

Gene position: 1711023-1712120 (Clockwise)

Preceding gene: 68536537

Following gene: 68536540

Centisome position: 69.48

GC content: 63.39

Gene sequence:

>1098_bases
ATGGAAGAAGAGTGGAAACAATTACCTATCAGCCACCAATCAGCAACAGAAAAGAGCTTGAAGATCATGTCTACTGAGCA
CATCCCTGCTGTCTCCCCCAACCCGGAGGCTCCAGACCGCAACCTGGCGATGGAGCTGGTCCGCGTGACGGAAGCCGCCG
CCCTAGCCTCTGGCAAATGGGTTGGCCGTGGACAGAAAGAATCCGGTGACGGCGCAGCCGTGGATGCGATGCGCCAGATG
ATCAACTCCGTGGAAATGGACGGTGTTGTCGTGATCGGCGAGGGCGAGAAGGACGAAGCTCCCATGCTGTTCAACGGCGA
GCAGGTCGGCACCGGCAACGGCCCGGCGGTGGACATCGCAGTAGACCCTGTCGACGGCACCACCCTGATGGCCGAAGGCC
GCCCGAACGCCATCTCCGTGATCGCCGCTGCCGAGCGTGGCTCTATGTACGACCCGTCGGCAGTGTTCTACATGAAGAAG
ATCGCCGTCGGCCCGGAGGCCGTGGGCAAGGTAGACATCGACGCGCCAGTCGCTGACAACATCAATGCTGTCGCCAAGGC
CAAGGGCACCGTCCCAGGTGACATCACCGTCGTCGTGCTGGACCGCCCGCGCCATGCGGACCTGATCCGCGAGATCCGCG
AGGCTGGCGCAAAGGTCCGCCTGATCGGCGACGGCGATGTGGCCGGTGCCGTGGCAACCGCCCAGGACACCTCCACCAAC
TCCGTGGACATCATGATGGGCATCGGTGGCACCCCGGAGGGCGTTATCGCCGCCGCCGCTATGAAGTGCATGGGCGGCGA
GATCCAGGGCAAGCTGTGGCCGAAGGACGAGGCTGAGCGCCAGAAGGCTCTGGACGCTGGCCACGACCTCAACCGCGTGC
TGACCACCAACGACCTGGTGAACTCCGAGCACTGCTACTTCGTGGCCACCGGCGTGACCAACGGCGATATGGTGCGCGGT
GTCTCCTACCACCAGAACTCCGCCACCACCCGTTCCCTGGTCATGCGCTCTCGCTCCGGCACGATCCGCTTCATCGAGTC
GCAGCACCAGCTGGCGAAGCTGCAGTCCTACTCCGTGTTGGATTACACCCGTAACTAG

Upstream 100 bases:

>100_bases
CCAAATCAGCACTGCGCAAGCCTCGGCTTAACCCTAGGTAGGGCTAGAAAGCGAAACTCAAGGCCTAGCAAAGGCAACGC
CCGGGGGTAAATGAGGCACA

Downstream 100 bases:

>100_bases
CTCTTTTTGTGACGCCCCCACGCCGCCACCGCGCAGCAGGCCTTTTAGGTAGATTGGGCGGTGTCCGTGCGGGGCACGAA
AGACTATCCGCTTTCCCACG

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MEEEWKQLPISHQSATEKSLKIMSTEHIPAVSPNPEAPDRNLAMELVRVTEAAALASGKWVGRGQKESGDGAAVDAMRQM
INSVEMDGVVVIGEGEKDEAPMLFNGEQVGTGNGPAVDIAVDPVDGTTLMAEGRPNAISVIAAAERGSMYDPSAVFYMKK
IAVGPEAVGKVDIDAPVADNINAVAKAKGTVPGDITVVVLDRPRHADLIREIREAGAKVRLIGDGDVAGAVATAQDTSTN
SVDIMMGIGGTPEGVIAAAAMKCMGGEIQGKLWPKDEAERQKALDAGHDLNRVLTTNDLVNSEHCYFVATGVTNGDMVRG
VSYHQNSATTRSLVMRSRSGTIRFIESQHQLAKLQSYSVLDYTRN

Sequences:

>Translated_365_residues
MEEEWKQLPISHQSATEKSLKIMSTEHIPAVSPNPEAPDRNLAMELVRVTEAAALASGKWVGRGQKESGDGAAVDAMRQM
INSVEMDGVVVIGEGEKDEAPMLFNGEQVGTGNGPAVDIAVDPVDGTTLMAEGRPNAISVIAAAERGSMYDPSAVFYMKK
IAVGPEAVGKVDIDAPVADNINAVAKAKGTVPGDITVVVLDRPRHADLIREIREAGAKVRLIGDGDVAGAVATAQDTSTN
SVDIMMGIGGTPEGVIAAAAMKCMGGEIQGKLWPKDEAERQKALDAGHDLNRVLTTNDLVNSEHCYFVATGVTNGDMVRG
VSYHQNSATTRSLVMRSRSGTIRFIESQHQLAKLQSYSVLDYTRN
>Mature_365_residues
MEEEWKQLPISHQSATEKSLKIMSTEHIPAVSPNPEAPDRNLAMELVRVTEAAALASGKWVGRGQKESGDGAAVDAMRQM
INSVEMDGVVVIGEGEKDEAPMLFNGEQVGTGNGPAVDIAVDPVDGTTLMAEGRPNAISVIAAAERGSMYDPSAVFYMKK
IAVGPEAVGKVDIDAPVADNINAVAKAKGTVPGDITVVVLDRPRHADLIREIREAGAKVRLIGDGDVAGAVATAQDTSTN
SVDIMMGIGGTPEGVIAAAAMKCMGGEIQGKLWPKDEAERQKALDAGHDLNRVLTTNDLVNSEHCYFVATGVTNGDMVRG
VSYHQNSATTRSLVMRSRSGTIRFIESQHQLAKLQSYSVLDYTRN

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Is essential for growth on gluconeogenic carbon sources. Also displays a low activity toward glucose 6- phosphate, and fructose 6-phosphate, glycerol 3-phosphate, ribulose 1,5-

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=329, Percent_Identity=45.2887537993921, Blast_Score=274, Evalue=6e-75,
Organism=Escherichia coli, GI1789298, Length=324, Percent_Identity=43.8271604938272, Blast_Score=231, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 38721; Mature: 38721

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEEWKQLPISHQSATEKSLKIMSTEHIPAVSPNPEAPDRNLAMELVRVTEAAALASGKW
CCCCHHHCCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
VGRGQKESGDGAAVDAMRQMINSVEMDGVVVIGEGEKDEAPMLFNGEQVGTGNGPAVDIA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCEECCCCCCEEEEE
VDPVDGTTLMAEGRPNAISVIAAAERGSMYDPSAVFYMKKIAVGPEAVGKVDIDAPVADN
ECCCCCCEEEECCCCCEEEEEEEECCCCCCCCHHHEEEHHHHCCCHHCCEEECCCCCCCC
INAVAKAKGTVPGDITVVVLDRPRHADLIREIREAGAKVRLIGDGDVAGAVATAQDTSTN
CCHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCCC
SVDIMMGIGGTPEGVIAAAAMKCMGGEIQGKLWPKDEAERQKALDAGHDLNRVLTTNDLV
CEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCC
NSEHCYFVATGVTNGDMVRGVSYHQNSATTRSLVMRSRSGTIRFIESQHQLAKLQSYSVL
CCCCEEEEEECCCCCCEEECEEECCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHCCEEE
DYTRN
EECCC
>Mature Secondary Structure
MEEEWKQLPISHQSATEKSLKIMSTEHIPAVSPNPEAPDRNLAMELVRVTEAAALASGKW
CCCCHHHCCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
VGRGQKESGDGAAVDAMRQMINSVEMDGVVVIGEGEKDEAPMLFNGEQVGTGNGPAVDIA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCEECCCCCCEEEEE
VDPVDGTTLMAEGRPNAISVIAAAERGSMYDPSAVFYMKKIAVGPEAVGKVDIDAPVADN
ECCCCCCEEEECCCCCEEEEEEEECCCCCCCCHHHEEEHHHHCCCHHCCEEECCCCCCCC
INAVAKAKGTVPGDITVVVLDRPRHADLIREIREAGAKVRLIGDGDVAGAVATAQDTSTN
CCHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCCC
SVDIMMGIGGTPEGVIAAAAMKCMGGEIQGKLWPKDEAERQKALDAGHDLNRVLTTNDLV
CEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCC
NSEHCYFVATGVTNGDMVRGVSYHQNSATTRSLVMRSRSGTIRFIESQHQLAKLQSYSVL
CCCCEEEEEECCCCCCEEECEEECCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHCCEEE
DYTRN
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]