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The map label for this gene is pmbA [H]

Identifier: 66767838

GI number: 66767838

Start: 1821556

End: 1822923

Strand: Direct

Name: pmbA [H]

Synonym: XC_1512

Alternate gene names: 66767838

Gene position: 1821556-1822923 (Clockwise)

Preceding gene: 66767836

Following gene: 66767839

Centisome position: 35.38

GC content: 68.64

Gene sequence:

>1368_bases
TTGAACGCACTCTCCTCCGAAACCCGTGTGACCGACGACAGCCTGCAGCGCCTGGAGGCACTCACCGACATCTCTCAGCG
GCTGCTCGAGCGCGCCCGCGCCGCCGGCGCGACCCAGGCCGAAGTGAGCTGCAGCGAAGAACGTGGTCTGGACGTGAACG
TGCGGCTCGGCGAGGTGGAAACGGTCGAGTCCACGCGCGATCGCGGCATTGCGGTCACGGTGTACTTCGGCAAGCGCAAG
GGCAGTGCGAGCACCGCCGACCTGCAGGAATCCAGCCTGGAGGCCACCGTTGCGCAGGCCTGCGCCATTGCCCGCTATAC
CGAAGATGACCCCGCCGCCGGCCTGGCCGATGCGGAGCTGATGGCGCGCGACTTCCCCGAGCTGGACAGCTGGCACCCGT
GGGCGCTGGATGCCGACACCGCCGTGGACCTGGCGCTGGCCTGCGAAAACGCCGGCCGGCAGGCCGATGCGCGGATCAGT
AACTCCGATGGCGCCTCGGCCAGTACCGGGCTCAGCCTGTCGGTGTATGCCAACTCGCACGGATTCATCGGGCGCGAGCG
TGGCACCCATCATTCGATCAGCTGCGCGCTGATTGCCGGGCAGGGCGATGGCATGCAGCGCGATGGTTGGTACAGCAGTG
CGCTGGCGCGCGAAGACCTGGAAGCGCCGGACGCGATCGGCCGGCATGCCGCCGCGCGCACCGTGGCACGGTTGCAGCCG
CGCTCGCTGCCGACCGGCCAGTTGCCAGTGCTGTTCGCGCCGGAAGTGGCACGCTCGCTCGTTGGGCATCTGCTCGGTGC
AGTGTCCGGCGGTGCGTTGTACCGCCGCGCCAGCTTCCTGCTTGATAGCGTCGGCACCCAGCTGTTTCCCGACTGGTTCG
GTATCGAGGAATTGCCGCACTTGCGTCGCGGCCTGCGCTCGGCCGCGTTCGACGGGGAAGGCGTGGCCACGCGTCGCTCG
GCTCTGGTCGACGGCGGCGTGCTGCAGCGTTATGTGCTGGGCAGCTATTCGGCGCGCAAGCTCGGGCTGCAGACCACCGC
CAATGCCGGCGGGGTGCACAACCTGCAGGTGACCGCCAATGCCGGCGACCTGGCATCGATGGTCGCCGGCATGTCGCGCG
GGCTGCTGGTCACCGAGCTGATGGGCAACGGCGTCAACGCGGTGACCGGCGACTATTCGCGCGGTGCCGGCGGGTTCTGG
GTCGAGAACGGCGAGATCGCCTATCCGGTCGACGGGCTGACCATTGCCGGCAACCTGCGCGACATGTTTGCCGGGATCGA
AGCGGTGGGCAGCGATGTCGACCCGCGCTCGCACGTCAAGATCGGCTCGGTGCTGATCAATCGCATGACCGTGGCCGGCG
ACAGCTGA

Upstream 100 bases:

>100_bases
ATGGCCGAGCGTTCTGCGGAAGGATCCGCATCCAAATTCAGACAGTCCGGCCACGATGGCCGGGCTTTCGCGGACGGATT
CGCATCCAAAGGATAAAGCA

Downstream 100 bases:

>100_bases
GTCACCCGCCCAGTAACTGCGCCCGCCAGCGTCCCGGCGCTGGCGGACCCATGGCTTCCCGCACTGGTGGCGCGCGGATT
GGTTGCTATAGTCCGCCGCA

Product: PmbA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNALSSETRVTDDSLQRLEALTDISQRLLERARAAGATQAEVSCSEERGLDVNVRLGEVETVESTRDRGIAVTVYFGKRK
GSASTADLQESSLEATVAQACAIARYTEDDPAAGLADAELMARDFPELDSWHPWALDADTAVDLALACENAGRQADARIS
NSDGASASTGLSLSVYANSHGFIGRERGTHHSISCALIAGQGDGMQRDGWYSSALAREDLEAPDAIGRHAAARTVARLQP
RSLPTGQLPVLFAPEVARSLVGHLLGAVSGGALYRRASFLLDSVGTQLFPDWFGIEELPHLRRGLRSAAFDGEGVATRRS
ALVDGGVLQRYVLGSYSARKLGLQTTANAGGVHNLQVTANAGDLASMVAGMSRGLLVTELMGNGVNAVTGDYSRGAGGFW
VENGEIAYPVDGLTIAGNLRDMFAGIEAVGSDVDPRSHVKIGSVLINRMTVAGDS

Sequences:

>Translated_455_residues
MNALSSETRVTDDSLQRLEALTDISQRLLERARAAGATQAEVSCSEERGLDVNVRLGEVETVESTRDRGIAVTVYFGKRK
GSASTADLQESSLEATVAQACAIARYTEDDPAAGLADAELMARDFPELDSWHPWALDADTAVDLALACENAGRQADARIS
NSDGASASTGLSLSVYANSHGFIGRERGTHHSISCALIAGQGDGMQRDGWYSSALAREDLEAPDAIGRHAAARTVARLQP
RSLPTGQLPVLFAPEVARSLVGHLLGAVSGGALYRRASFLLDSVGTQLFPDWFGIEELPHLRRGLRSAAFDGEGVATRRS
ALVDGGVLQRYVLGSYSARKLGLQTTANAGGVHNLQVTANAGDLASMVAGMSRGLLVTELMGNGVNAVTGDYSRGAGGFW
VENGEIAYPVDGLTIAGNLRDMFAGIEAVGSDVDPRSHVKIGSVLINRMTVAGDS
>Mature_455_residues
MNALSSETRVTDDSLQRLEALTDISQRLLERARAAGATQAEVSCSEERGLDVNVRLGEVETVESTRDRGIAVTVYFGKRK
GSASTADLQESSLEATVAQACAIARYTEDDPAAGLADAELMARDFPELDSWHPWALDADTAVDLALACENAGRQADARIS
NSDGASASTGLSLSVYANSHGFIGRERGTHHSISCALIAGQGDGMQRDGWYSSALAREDLEAPDAIGRHAAARTVARLQP
RSLPTGQLPVLFAPEVARSLVGHLLGAVSGGALYRRASFLLDSVGTQLFPDWFGIEELPHLRRGLRSAAFDGEGVATRRS
ALVDGGVLQRYVLGSYSARKLGLQTTANAGGVHNLQVTANAGDLASMVAGMSRGLLVTELMGNGVNAVTGDYSRGAGGFW
VENGEIAYPVDGLTIAGNLRDMFAGIEAVGSDVDPRSHVKIGSVLINRMTVAGDS

Specific function: May facilitate the secretion of the peptide antibiotic microcin B17 (MccB17) by completing its maturation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1790682, Length=414, Percent_Identity=49.7584541062802, Blast_Score=419, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 47856; Mature: 47856

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALSSETRVTDDSLQRLEALTDISQRLLERARAAGATQAEVSCSEERGLDVNVRLGEVE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECCCH
TVESTRDRGIAVTVYFGKRKGSASTADLQESSLEATVAQACAIARYTEDDPAAGLADAEL
HHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
MARDFPELDSWHPWALDADTAVDLALACENAGRQADARISNSDGASASTGLSLSVYANSH
HHHCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCC
GFIGRERGTHHSISCALIAGQGDGMQRDGWYSSALAREDLEAPDAIGRHAAARTVARLQP
CCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
RSLPTGQLPVLFAPEVARSLVGHLLGAVSGGALYRRASFLLDSVGTQLFPDWFGIEELPH
CCCCCCCCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LRRGLRSAAFDGEGVATRRSALVDGGVLQRYVLGSYSARKLGLQTTANAGGVHNLQVTAN
HHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCHHHCCCEECCCCCCEEEEEEEEC
AGDLASMVAGMSRGLLVTELMGNGVNAVTGDYSRGAGGFWVENGEIAYPVDGLTIAGNLR
CHHHHHHHHHHHCCEEHHHHHCCCCCEECCCCCCCCCCEEEECCEEEECCCCEEEECCHH
DMFAGIEAVGSDVDPRSHVKIGSVLINRMTVAGDS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCC
>Mature Secondary Structure
MNALSSETRVTDDSLQRLEALTDISQRLLERARAAGATQAEVSCSEERGLDVNVRLGEVE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECCCH
TVESTRDRGIAVTVYFGKRKGSASTADLQESSLEATVAQACAIARYTEDDPAAGLADAEL
HHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
MARDFPELDSWHPWALDADTAVDLALACENAGRQADARISNSDGASASTGLSLSVYANSH
HHHCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCC
GFIGRERGTHHSISCALIAGQGDGMQRDGWYSSALAREDLEAPDAIGRHAAARTVARLQP
CCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
RSLPTGQLPVLFAPEVARSLVGHLLGAVSGGALYRRASFLLDSVGTQLFPDWFGIEELPH
CCCCCCCCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LRRGLRSAAFDGEGVATRRSALVDGGVLQRYVLGSYSARKLGLQTTANAGGVHNLQVTAN
HHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCHHHCCCEECCCCCCEEEEEEEEC
AGDLASMVAGMSRGLLVTELMGNGVNAVTGDYSRGAGGFWVENGEIAYPVDGLTIAGNLR
CHHHHHHHHHHHCCEEHHHHHCCCCCEECCCCCCCCCCEEEECCEEEECCCCEEEECCHH
DMFAGIEAVGSDVDPRSHVKIGSVLINRMTVAGDS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]