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The map label for this gene is tldD [H]

Identifier: 66767836

GI number: 66767836

Start: 1819161

End: 1820606

Strand: Direct

Name: tldD [H]

Synonym: XC_1510

Alternate gene names: 66767836

Gene position: 1819161-1820606 (Clockwise)

Preceding gene: 66767834

Following gene: 66767838

Centisome position: 35.33

GC content: 67.36

Gene sequence:

>1446_bases
ATGACCGACACCGCCCTGACTCTGGCCGAATCCCGGCTGCTGCTTCCTTCCGGCCTGGATACCGGCCACCTCGACCGCAC
CTTCGGCGCCCTGCTGGGCCCCGGCATCGACTTCGGCGACCTGTACTTCCAGCATTCGCGACGCGAGAGCTGGAGTGTGG
AAGACGGCATCGTCAAGGACGGTGCGCATTCCATCGAACAAGGCGTGGGCGTGCGCGCCATCTCCGGCGAAAAAACCGGA
TTTGCCTATTCCGACGACATCCAGCGCGAAGCCTTGCTGGAAGCGGCCCAGTCGGCGCGCGCGATCTCACGCGACGGCGG
CGCGCAATCCACCCGCACGCTGGTGCGCGGCAACGGCCGTGCGCTGTATCCGGCCACCGACCCGATCGACGACATGGACA
GCGCCACCAAGGTGGACCTGCTGCGCCGCATCGACCAGTACCTGCGCGCTGCGGACGCGCGCGTCAAGCAGGTGATGGTG
AATTTGTCCGGCGGCGTGGACACGGTACTGATCGCGCGCAGTGACGGTGTGCTGGCCGCCGACGTGCGCCCGCTGGTGCG
CTTGAACGTGCAGGTGATCGTCGAACACGGCGGCCGCCGCGAGTCCGGCTATTCCGGTGGCGGTGGCCGTTACGGCTATG
CCGAGCTGTTCGCCGATGGCCGCCCGGAAGGTTTTGCGCGTGAAGCATTGCGCCAGGCGCTGGTCAACCTGGATGCGATT
CCCGCGCCGGCCGGCGTGATGCCGGTGGTGCTGGGGCCGGGCTGGCCGGGCGTGCTGCTGCACGAAGCGGTGGGCCATGG
GCTGGAAGGCGACTTCAATCGCAAGGGCACCAGCGTCTACGCCGGCCGCATTGGCGAGCGCGTGGCCTCCAAGGGCGTGA
CCATCGTCGATGACGGCACCCTGGATGGACGCCGCGGCTCGCTCAATATCGATGACGAAGGCACGCCCAGCCAGTGCACC
ACGCTGATCGAAGACGGCGTGCTGGTCGGCTACATGCAGGACACCCACAACGCGCGCCTGATGGGCGTGGCGCCCACCGG
CAATGGCCGCCGCGAATCCTTCGCGCACCTGACCATGCCGCGCATGACCAATACCTACATGCGTGCCGGCGAGCACGACC
CGCAAGAGATGATCCGCTCGGTCAAGAAGGGCATCTATGCGGTCAACTTCGGTGGCGGCCAGGTCGACATCACCAGCGGC
AAGTACGTGTTCTCCGCAACCGAGGCCTACCTGATCGAAGACGGCAAGGTCACCGCGCCCGTGAAGGGCGCCACCCTGAT
CGGCAACGGCCCGGAAACCATGCAGAAGGTGCGCATGATCGGCAACGATCTGGCCCTGGACGAAGGCGTGGGCGTCTGCG
GCAAGGACGGGCAGAGCGTGCCGGTCGGCGTGGGTCAGCCGTCGCTGCTGATCGACGGCATCACCGTGGGCGGAACGCGG
GCCTGA

Upstream 100 bases:

>100_bases
ATGCGTGCGCGGTGGCTGGCAGCGGGCTGGCGATGATAGCCGCGTGCCACGTTCAGCCGCGCGACTTGTCTCCCCGGCGC
GAGACCCCCATCCTGACCAC

Downstream 100 bases:

>100_bases
GATGCCGGGAATCGGGAATCGGGAGTGGGGAATCGCAACGGCAGGGGCGCAGAGCGGTGCGTTGGGCGGTTGCGGTTTGC
CGGTTCAGCAGAGGGGAATC

Product: TldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTDTALTLAESRLLLPSGLDTGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKDGAHSIEQGVGVRAISGEKTG
FAYSDDIQREALLEAAQSARAISRDGGAQSTRTLVRGNGRALYPATDPIDDMDSATKVDLLRRIDQYLRAADARVKQVMV
NLSGGVDTVLIARSDGVLAADVRPLVRLNVQVIVEHGGRRESGYSGGGGRYGYAELFADGRPEGFAREALRQALVNLDAI
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASKGVTIVDDGTLDGRRGSLNIDDEGTPSQCT
TLIEDGVLVGYMQDTHNARLMGVAPTGNGRRESFAHLTMPRMTNTYMRAGEHDPQEMIRSVKKGIYAVNFGGGQVDITSG
KYVFSATEAYLIEDGKVTAPVKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTR
A

Sequences:

>Translated_481_residues
MTDTALTLAESRLLLPSGLDTGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKDGAHSIEQGVGVRAISGEKTG
FAYSDDIQREALLEAAQSARAISRDGGAQSTRTLVRGNGRALYPATDPIDDMDSATKVDLLRRIDQYLRAADARVKQVMV
NLSGGVDTVLIARSDGVLAADVRPLVRLNVQVIVEHGGRRESGYSGGGGRYGYAELFADGRPEGFAREALRQALVNLDAI
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASKGVTIVDDGTLDGRRGSLNIDDEGTPSQCT
TLIEDGVLVGYMQDTHNARLMGVAPTGNGRRESFAHLTMPRMTNTYMRAGEHDPQEMIRSVKKGIYAVNFGGGQVDITSG
KYVFSATEAYLIEDGKVTAPVKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTR
A
>Mature_480_residues
TDTALTLAESRLLLPSGLDTGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKDGAHSIEQGVGVRAISGEKTGF
AYSDDIQREALLEAAQSARAISRDGGAQSTRTLVRGNGRALYPATDPIDDMDSATKVDLLRRIDQYLRAADARVKQVMVN
LSGGVDTVLIARSDGVLAADVRPLVRLNVQVIVEHGGRRESGYSGGGGRYGYAELFADGRPEGFAREALRQALVNLDAIP
APAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASKGVTIVDDGTLDGRRGSLNIDDEGTPSQCTT
LIEDGVLVGYMQDTHNARLMGVAPTGNGRRESFAHLTMPRMTNTYMRAGEHDPQEMIRSVKKGIYAVNFGGGQVDITSGK
YVFSATEAYLIEDGKVTAPVKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTRA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=479, Percent_Identity=62.6304801670146, Blast_Score=574, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50873; Mature: 50742

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTALTLAESRLLLPSGLDTGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKD
CCCCCEEHHHCCEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHC
GAHSIEQGVGVRAISGEKTGFAYSDDIQREALLEAAQSARAISRDGGAQSTRTLVRGNGR
CHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCC
ALYPATDPIDDMDSATKVDLLRRIDQYLRAADARVKQVMVNLSGGVDTVLIARSDGVLAA
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCEEEE
DVRPLVRLNVQVIVEHGGRRESGYSGGGGRYGYAELFADGRPEGFAREALRQALVNLDAI
CCCHHHHEEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASKGVTIVDDGT
CCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEECCC
LDGRRGSLNIDDEGTPSQCTTLIEDGVLVGYMQDTHNARLMGVAPTGNGRRESFAHLTMP
CCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCCCCCCCHHEEECC
RMTNTYMRAGEHDPQEMIRSVKKGIYAVNFGGGQVDITSGKYVFSATEAYLIEDGKVTAP
HHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEEEEECCEEECC
VKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTR
CCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
A
C
>Mature Secondary Structure 
TDTALTLAESRLLLPSGLDTGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKD
CCCCEEHHHCCEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHC
GAHSIEQGVGVRAISGEKTGFAYSDDIQREALLEAAQSARAISRDGGAQSTRTLVRGNGR
CHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCC
ALYPATDPIDDMDSATKVDLLRRIDQYLRAADARVKQVMVNLSGGVDTVLIARSDGVLAA
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCEEEE
DVRPLVRLNVQVIVEHGGRRESGYSGGGGRYGYAELFADGRPEGFAREALRQALVNLDAI
CCCHHHHEEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASKGVTIVDDGT
CCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEECCC
LDGRRGSLNIDDEGTPSQCTTLIEDGVLVGYMQDTHNARLMGVAPTGNGRRESFAHLTMP
CCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCCCCCCCHHEEECC
RMTNTYMRAGEHDPQEMIRSVKKGIYAVNFGGGQVDITSGKYVFSATEAYLIEDGKVTAP
HHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEEEEECCEEECC
VKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTR
CCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]