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The map label for this gene is hprK [H]

Identifier: 66767635

GI number: 66767635

Start: 1598815

End: 1599765

Strand: Reverse

Name: hprK [H]

Synonym: XC_1308

Alternate gene names: 66767635

Gene position: 1599765-1598815 (Counterclockwise)

Preceding gene: 66767636

Following gene: 66767634

Centisome position: 31.07

GC content: 64.98

Gene sequence:

>951_bases
ATGAATACCAGCATCACCGCACGTGAACTGTTCGACCAGCAGCGCGACAAGCTGGCACTGCGCTGGGTTGCGGGGCAAAA
GGGGGAACACCGCGAGATCCAGGCCGGCAGCAATAATGCGCGCCGGCCCTCGCTGGCCGGCTATCTCAATGTGATCTATC
CGAACAAGGTGCAGATCCTCGGTACCGAGGAGCTGGCCTGGCTGGATTCGCTGGATGCGCGGCAACGCTGGGAGACGATC
GAAAAGATCATCCAGGTGCAGCCGCTGGCACTGGCGATCAGCAAGAACCAGTCCTGCCCGGAAGATCTGCGCGCGGCGGC
GGATGAATCCAATACGCCGCTGTGGATCTCGCCCAAGCGCGGCCATGAGCTGCTCAATCATCTGTCCTACCACCTTGCGC
GCACGCTGGCGCCGCGGGTCACGCTGCATGGCGTGTTCATGGAGATCTATTCGATCGGCGTATTGATCACCGGCGAAGCC
GGCTCGGGCAAGAGCGAACTGGCGCTGGAACTGCTCAGCCGCGGGCACCGCCTGGTGGCCGACGACGCACCGGAATTCAC
CCAGATCGCGCCGGACGTACTCGACGGCACCTGCCCCGAGCTGTTGCAGGATCTGCTGGAAGTGCGCGGCCTGGGCGTGT
TGAACGTGCGCGACATGTTCGGCGACACCGCGGTGAAGAAGAACAAGTACCTGCGCCTGATCGTGCACCTGACCCGGCCG
ATGACCGAGCCCACGCCTTCCGGCTATGAGCGCCTGACCGGTGATTCCGGCAGCCGCCACGTGCTGGATCTGGACGTGCC
GCTGATCACCCTGCCGGTGATGCCCGGCCGCAACCTGGCCGTGCTGACCGAGGCGGCCACCCGCCTGCACATCCTGCGCA
CCAAGGGCATCGACCCGGCGGCGATGTTCATCGCCCGCCACAGCAACCTGCTGGAGCGACGCACCCCATGA

Upstream 100 bases:

>100_bases
TTTCTGACAGCCATTTTCGCCAGCAGCTGCGCGCCGCGCCCGATGCGCAAGCGCTGATGGCGCTGCTGACTGAGGTACCG
CCTCCACACGCGAGCGCCGC

Downstream 100 bases:

>100_bases
GCATTGCCGCGTCCACCTTGATGATCGTCAGCGGGTTGTCCGGCTCCGGCAAGTCGGTGGCGCTGAAGACCTTCGAAGAC
CTCGACTATTACTGTTCGGA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNTSITARELFDQQRDKLALRWVAGQKGEHREIQAGSNNARRPSLAGYLNVIYPNKVQILGTEELAWLDSLDARQRWETI
EKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISPKRGHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEA
GSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRP
MTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPAAMFIARHSNLLERRTP

Sequences:

>Translated_316_residues
MNTSITARELFDQQRDKLALRWVAGQKGEHREIQAGSNNARRPSLAGYLNVIYPNKVQILGTEELAWLDSLDARQRWETI
EKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISPKRGHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEA
GSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRP
MTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPAAMFIARHSNLLERRTP
>Mature_316_residues
MNTSITARELFDQQRDKLALRWVAGQKGEHREIQAGSNNARRPSLAGYLNVIYPNKVQILGTEELAWLDSLDARQRWETI
EKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISPKRGHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEA
GSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRP
MTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPAAMFIARHSNLLERRTP

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 35155; Mature: 35155

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSITARELFDQQRDKLALRWVAGQKGEHREIQAGSNNARRPSLAGYLNVIYPNKVQIL
CCCCCHHHHHHHHHHHHEEEEEECCCCCCCCEEECCCCCCCCCCHHHEEEEECCCEEEEE
GTEELAWLDSLDARQRWETIEKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISPKR
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCCCCEEECCHH
GHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEAGSGKSELALELLSRGHRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCEEEC
DDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRP
CCCCHHHHHCHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHCCHHHCCCCCEEEEEEECCC
MTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPA
CCCCCCCCHHHHCCCCCCCEEEEECCCEEEEECCCCCCEEEEHHHHHHEEEEECCCCCHH
AMFIARHSNLLERRTP
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTSITARELFDQQRDKLALRWVAGQKGEHREIQAGSNNARRPSLAGYLNVIYPNKVQIL
CCCCCHHHHHHHHHHHHEEEEEECCCCCCCCEEECCCCCCCCCCHHHEEEEECCCEEEEE
GTEELAWLDSLDARQRWETIEKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISPKR
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCCCCEEECCHH
GHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEAGSGKSELALELLSRGHRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCEEEC
DDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRP
CCCCHHHHHCHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHCCHHHCCCCCEEEEEEECCC
MTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPA
CCCCCCCCHHHHCCCCCCCEEEEECCCEEEEECCCCCCEEEEHHHHHHEEEEECCCCCHH
AMFIARHSNLLERRTP
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]