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The map label for this gene is sasA [H]

Identifier: 66767318

GI number: 66767318

Start: 1182535

End: 1183863

Strand: Reverse

Name: sasA [H]

Synonym: XC_0987

Alternate gene names: 66767318

Gene position: 1183863-1182535 (Counterclockwise)

Preceding gene: 66767322

Following gene: 66767315

Centisome position: 22.99

GC content: 67.72

Gene sequence:

>1329_bases
GTGCGCGACGCGATGTCGCACCCTTCACACACGGCCGCCACCGGCAGCGATCGCCTGGACGGGCTGCGGTGCACACAATC
CGGGCACAGCCATAGCCTATGCTTGGCGCCTATCACTTTGACCCGTGCGCGCATGAGTACTGTCCTGTCCGATCCAGCGG
CCGAGCCCCTGCCGTGTGCGCCCAAGCCGCCGAGCGAGGCCTTGCGCCTGCAGGCCCTGCGCAGCTACGGCATCCTCGAC
ACCCCGCGCGAGGCCGCCTTCGAGGACATCACCAAGCTGGCCTCGATCATCTGCCAGACCCCGATCGCGCTGATCAGCCT
GGTGGATGCGGACCGGCAGTGGTTCAAGAGCGAGCGTGGCATGGGCGAACGCGAGACACCGTTGTTCAAGTCGATGTGCG
CGCACGCCCTGCTCGATAACGACGTACTGGTGGTGCCCGACACCCGCGAAGACGCGCGCTTTTCGCGCAACCCGCTGGTG
ACCGGCGAATCGCCGCTGTATTTCTATGCCGGTGCGCTGCTCAAGACTCCGGACGGCCTGCCGCTGGGCACGGTCTGCGT
GCTGGACCGGCAACCACGCCAGCTCACCGACGAACAGGTCGATGCACTGCGCGCGCTGGCGCGCCAGACCATGGCCCAGC
TGGAGTTGCGCCGCGCGTTGTTGATCGCCGAAGAGTCCAACCGTTACCGCAGCCGTCTGATGGCCATCGCCGGCCACGAT
CTCAAGACCCCCCTGCGCACGGCCGCCTATGCCATCGACAAGATGCGCCGGCATGCCAACGTGGACACCATTCCCACCCT
GGTCACCGCACGTGATGCGATCGGCACCGTGGCGCGCAGCCTGGACGAACTGGCCGCATTGGCGGCGGCCAGCAAGTCGG
CCAGCCCGGATCTGCAGCCGCTGGCGCTGGAAGACGTGATCCACGCGGTGCTCGGCGTGTGGCGCCAGCCGGCCAGGGAC
AAGTGCCTGTCGCTGCGGCATGTGCCCACCTCCCTGCGCGTGCGCAGCCATTCCACCTTGCTGACCACCTTGATCGGCAA
TCTGGTCGGCAATGCAGTCAAGTACACCGAACGCGGCCAGGTGCTGGTGGGCTGCCGGCGCCGTCCCGGCCACGCGGTGG
TGGAAGTCATCGACAGCGGCATCGGCTTGAATCTGGAGCACCCCGAAGACGTGTTCCAGGCGTTCCGCCAGGCCGACCCG
GGCAGCGACGGCCTGGGCATCGGCTTGTGGATCGTGCATCGCACCGCCGAAACGCTGGGCTGCCAGGTCGAAGTGCGCCC
GCGCCCGAGTGGCGGCACGCGCTTTTCGGTCACCATTCCGCTGGCCTGA

Upstream 100 bases:

>100_bases
GCCAGCACGGCAAGCGACTGCAACACGCGGTGGTGGTGGAGAAAACGGAGCATCCGGCGAGTGTAAGCCGGTGCATCACA
ACCGGCGATGGTCGCGGCCG

Downstream 100 bases:

>100_bases
ACAAAAAATGGCGGACCCGGGCTCCCGTCCCGAATCCGCCACCAAGCACGCCAGGCCTCTCCCCAGGGACCCGGGTGCGC
CAGTCGTTCAAGTCGCGCAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MRDAMSHPSHTAATGSDRLDGLRCTQSGHSHSLCLAPITLTRARMSTVLSDPAAEPLPCAPKPPSEALRLQALRSYGILD
TPREAAFEDITKLASIICQTPIALISLVDADRQWFKSERGMGERETPLFKSMCAHALLDNDVLVVPDTREDARFSRNPLV
TGESPLYFYAGALLKTPDGLPLGTVCVLDRQPRQLTDEQVDALRALARQTMAQLELRRALLIAEESNRYRSRLMAIAGHD
LKTPLRTAAYAIDKMRRHANVDTIPTLVTARDAIGTVARSLDELAALAAASKSASPDLQPLALEDVIHAVLGVWRQPARD
KCLSLRHVPTSLRVRSHSTLLTTLIGNLVGNAVKYTERGQVLVGCRRRPGHAVVEVIDSGIGLNLEHPEDVFQAFRQADP
GSDGLGIGLWIVHRTAETLGCQVEVRPRPSGGTRFSVTIPLA

Sequences:

>Translated_442_residues
MRDAMSHPSHTAATGSDRLDGLRCTQSGHSHSLCLAPITLTRARMSTVLSDPAAEPLPCAPKPPSEALRLQALRSYGILD
TPREAAFEDITKLASIICQTPIALISLVDADRQWFKSERGMGERETPLFKSMCAHALLDNDVLVVPDTREDARFSRNPLV
TGESPLYFYAGALLKTPDGLPLGTVCVLDRQPRQLTDEQVDALRALARQTMAQLELRRALLIAEESNRYRSRLMAIAGHD
LKTPLRTAAYAIDKMRRHANVDTIPTLVTARDAIGTVARSLDELAALAAASKSASPDLQPLALEDVIHAVLGVWRQPARD
KCLSLRHVPTSLRVRSHSTLLTTLIGNLVGNAVKYTERGQVLVGCRRRPGHAVVEVIDSGIGLNLEHPEDVFQAFRQADP
GSDGLGIGLWIVHRTAETLGCQVEVRPRPSGGTRFSVTIPLA
>Mature_442_residues
MRDAMSHPSHTAATGSDRLDGLRCTQSGHSHSLCLAPITLTRARMSTVLSDPAAEPLPCAPKPPSEALRLQALRSYGILD
TPREAAFEDITKLASIICQTPIALISLVDADRQWFKSERGMGERETPLFKSMCAHALLDNDVLVVPDTREDARFSRNPLV
TGESPLYFYAGALLKTPDGLPLGTVCVLDRQPRQLTDEQVDALRALARQTMAQLELRRALLIAEESNRYRSRLMAIAGHD
LKTPLRTAAYAIDKMRRHANVDTIPTLVTARDAIGTVARSLDELAALAAASKSASPDLQPLALEDVIHAVLGVWRQPARD
KCLSLRHVPTSLRVRSHSTLLTTLIGNLVGNAVKYTERGQVLVGCRRRPGHAVVEVIDSGIGLNLEHPEDVFQAFRQADP
GSDGLGIGLWIVHRTAETLGCQVEVRPRPSGGTRFSVTIPLA

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=270, Percent_Identity=28.5185185185185, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=272, Percent_Identity=26.8382352941176, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=195, Percent_Identity=29.7435897435897, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=24.5689655172414, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788393, Length=225, Percent_Identity=24, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48123; Mature: 48123

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDAMSHPSHTAATGSDRLDGLRCTQSGHSHSLCLAPITLTRARMSTVLSDPAAEPLPCA
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCC
PKPPSEALRLQALRSYGILDTPREAAFEDITKLASIICQTPIALISLVDADRQWFKSERG
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MGERETPLFKSMCAHALLDNDVLVVPDTREDARFSRNPLVTGESPLYFYAGALLKTPDGL
CCCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHCCCCCCCCCCCHHEECCHHHCCCCCC
PLGTVCVLDRQPRQLTDEQVDALRALARQTMAQLELRRALLIAEESNRYRSRLMAIAGHD
CCCEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
LKTPLRTAAYAIDKMRRHANVDTIPTLVTARDAIGTVARSLDELAALAAASKSASPDLQP
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LALEDVIHAVLGVWRQPARDKCLSLRHVPTSLRVRSHSTLLTTLIGNLVGNAVKYTERGQ
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHHHHHHHCCCCCC
VLVGCRRRPGHAVVEVIDSGIGLNLEHPEDVFQAFRQADPGSDGLGIGLWIVHRTAETLG
EEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHHC
CQVEVRPRPSGGTRFSVTIPLA
CEEEEEECCCCCCEEEEEECCC
>Mature Secondary Structure
MRDAMSHPSHTAATGSDRLDGLRCTQSGHSHSLCLAPITLTRARMSTVLSDPAAEPLPCA
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCC
PKPPSEALRLQALRSYGILDTPREAAFEDITKLASIICQTPIALISLVDADRQWFKSERG
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MGERETPLFKSMCAHALLDNDVLVVPDTREDARFSRNPLVTGESPLYFYAGALLKTPDGL
CCCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHCCCCCCCCCCCHHEECCHHHCCCCCC
PLGTVCVLDRQPRQLTDEQVDALRALARQTMAQLELRRALLIAEESNRYRSRLMAIAGHD
CCCEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
LKTPLRTAAYAIDKMRRHANVDTIPTLVTARDAIGTVARSLDELAALAAASKSASPDLQP
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LALEDVIHAVLGVWRQPARDKCLSLRHVPTSLRVRSHSTLLTTLIGNLVGNAVKYTERGQ
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHHHHHHHCCCCCC
VLVGCRRRPGHAVVEVIDSGIGLNLEHPEDVFQAFRQADPGSDGLGIGLWIVHRTAETLG
EEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHHC
CQVEVRPRPSGGTRFSVTIPLA
CEEEEEECCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]