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The map label for this gene is cysH [H]

Identifier: 66767322

GI number: 66767322

Start: 1188160

End: 1188885

Strand: Reverse

Name: cysH [H]

Synonym: XC_0990

Alternate gene names: 66767322

Gene position: 1188885-1188160 (Counterclockwise)

Preceding gene: 66767323

Following gene: 66767318

Centisome position: 23.09

GC content: 66.39

Gene sequence:

>726_bases
ATGACCGCGCTGCCTGCCACATCGATCGCCGCTCCTTCGCTGGACGACCTGGACGCGCTCAACGCGCACCTGGAGACGCT
GCGCGCCGACGAACGCGTTGCCTGGGCGCTGCAGCACGGCCCGCAGCAGGCGGCGCTGTCGTCCAGCTTCGGCGCGCAGT
CGGCGGTGACGCTGCACCTGCTCACCCAGCAGCGCCCGGACATCCCGGTGATCCTGATCGACACCGGCTACCTGTTCCCG
GAGACCTACCGCTTTGCCGATGCATTGACCGAACGCCTTTCGCTCAACCTGCAGGTGTATCGCCCGCTGGTCAGCCGCGC
CTGGATGGAGGCACGCCATGGCCGTCTGTGGGAACAGGGCATGGTGGGCATCGACCAGTACAACAACCTGCGCAAGGTCG
AACCGATGCGCCGCGCACTGGACGAACTCAACGTCGGCACCTGGTTCACCGGCCTACGCCGCAGCCAGTCCGGTGGGCGT
GCGCAGACGCCGATCGTGCAGAAGCGCGGGGACCGCTACAAGATCAGCCCGATCGCCGACTGGACCGACCGCGACGTCTG
GCAATACCTGCAGGCGCACGCACTGCCGTATCACCCGCTGTGGGAACAGGGCTATGTGTCGATTGGTGACTTCCACACCA
CCCGTCGCTGGGAGCCGGGCATGCGCGAAGAAGACACGCGCTTCTTTGGGCTCAAGCGCGAGTGCGGCATCCACGAAGAC
ATCTGA

Upstream 100 bases:

>100_bases
GACACACCGATGAAGGCTTCGGCGACTTCCTGCATCGCAGCGGCCTGATCGCCCTGCCGCCCTACCCCACCCACCGTCAT
CTCGACCTGGAATTGCTCGC

Downstream 100 bases:

>100_bases
GCCGCGCGCAGCAGTGCGCAGGCCAGCGCCTCACCGCCGCAGCCTGCGCACGCTCCAGTAATGATCGAACGCCCACAACA
GCAGTAACGATGCGCCCATC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTALPATSIAAPSLDDLDALNAHLETLRADERVAWALQHGPQQAALSSSFGAQSAVTLHLLTQQRPDIPVILIDTGYLFP
ETYRFADALTERLSLNLQVYRPLVSRAWMEARHGRLWEQGMVGIDQYNNLRKVEPMRRALDELNVGTWFTGLRRSQSGGR
AQTPIVQKRGDRYKISPIADWTDRDVWQYLQAHALPYHPLWEQGYVSIGDFHTTRRWEPGMREEDTRFFGLKRECGIHED
I

Sequences:

>Translated_241_residues
MTALPATSIAAPSLDDLDALNAHLETLRADERVAWALQHGPQQAALSSSFGAQSAVTLHLLTQQRPDIPVILIDTGYLFP
ETYRFADALTERLSLNLQVYRPLVSRAWMEARHGRLWEQGMVGIDQYNNLRKVEPMRRALDELNVGTWFTGLRRSQSGGR
AQTPIVQKRGDRYKISPIADWTDRDVWQYLQAHALPYHPLWEQGYVSIGDFHTTRRWEPGMREEDTRFFGLKRECGIHED
I
>Mature_240_residues
TALPATSIAAPSLDDLDALNAHLETLRADERVAWALQHGPQQAALSSSFGAQSAVTLHLLTQQRPDIPVILIDTGYLFPE
TYRFADALTERLSLNLQVYRPLVSRAWMEARHGRLWEQGMVGIDQYNNLRKVEPMRRALDELNVGTWFTGLRRSQSGGRA
QTPIVQKRGDRYKISPIADWTDRDVWQYLQAHALPYHPLWEQGYVSIGDFHTTRRWEPGMREEDTRFFGLKRECGIHEDI

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=231, Percent_Identity=63.2034632034632, Blast_Score=313, Evalue=8e-87,
Organism=Saccharomyces cerevisiae, GI6325425, Length=239, Percent_Identity=33.8912133891213, Blast_Score=115, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27638; Mature: 27506

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALPATSIAAPSLDDLDALNAHLETLRADERVAWALQHGPQQAALSSSFGAQSAVTLHL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHEEEEE
LTQQRPDIPVILIDTGYLFPETYRFADALTERLSLNLQVYRPLVSRAWMEARHGRLWEQG
ECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHC
MVGIDQYNNLRKVEPMRRALDELNVGTWFTGLRRSQSGGRAQTPIVQKRGDRYKISPIAD
CCCHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHCCCEEEECCCCC
WTDRDVWQYLQAHALPYHPLWEQGYVSIGDFHTTRRWEPGMREEDTRFFGLKRECGIHED
CCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHCCCHHHCCCCCC
I
C
>Mature Secondary Structure 
TALPATSIAAPSLDDLDALNAHLETLRADERVAWALQHGPQQAALSSSFGAQSAVTLHL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHEEEEE
LTQQRPDIPVILIDTGYLFPETYRFADALTERLSLNLQVYRPLVSRAWMEARHGRLWEQG
ECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHC
MVGIDQYNNLRKVEPMRRALDELNVGTWFTGLRRSQSGGRAQTPIVQKRGDRYKISPIAD
CCCHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHCCCEEEECCCCC
WTDRDVWQYLQAHALPYHPLWEQGYVSIGDFHTTRRWEPGMREEDTRFFGLKRECGIHED
CCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHCCCHHHCCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]