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The map label for this gene is laaA [H]

Identifier: 66047444

GI number: 66047444

Start: 5022527

End: 5023450

Strand: Direct

Name: laaA [H]

Synonym: Psyr_4217

Alternate gene names: 66047444

Gene position: 5022527-5023450 (Clockwise)

Preceding gene: 66047443

Following gene: 66047445

Centisome position: 82.42

GC content: 56.82

Gene sequence:

>924_bases
ATGGCAGATATGACGATCAAGGAAGGTTTTGCGCCCTTTGGCGACTATCAGACGTGGTATCGCATCACAGGCGACCTGCA
CGGTCCCGGCACACCACTGGTCATTCTGCACGGCGGCCCCGGTTGTACGCACGATTACGTCGATGCGTTCAAGGACATCG
CCAGCACTGGCCGGGCCGTTATCCATTACGACCAGTTGGGTAACGGAAAGTCGACTCGACTGCCCCATAAGGGTCGCGAT
TTCTGGACGGTCGATCTGTTCCTGAGCGAACTCGACAATCTGCTTGCGCACCTGAGTATCAAAAACAACTACGCATTGCT
GGGCCAGTCGTGGGGCGGGATGCTGGCGGCAGAGCATGCCGTGCGCCAGCCTGCAGGGCTGAAGGCGCTGATCATCGCCA
ACTCCCCCGCAGACATGCTCACTTGGGTAAACGAGGCCAACCGGCTGCGCGAGGATCTGCCAGCCGACGTGCAGGCTGCG
TTGCTCAAGCACGAAGAGGCGGGAACATTGAAAGACCCGGAATACCTGAAAGCCTCGCGAGCATTCTATGACCGTCATGT
CTGCCGCATCACACCGTGGCCGGAGGAGGTAAAACGTACCTTCGACGCGATTGACGCCGATCCGACCGTGTACCACGCCA
TGAATGGCCCTACCGAGTTTCACGTCATCGGTACGATGAAGAACTGGACCATCGTTGATCGCTTGAAGCTCATCAATGTT
CCTGCCTTACTGATTTCCGGGAAGTATGACGAAGCCACACCGCTGGTCGTGAAGCCCTATGTGGATAACGTCCCCGACAT
CAGTTGGTCTGTCTTCGAAGAGTCCAGTCATATGCCCCATGTAGAGGAGCGAATGGCCTGTATGGGATGCATCGCAGGTT
TTCTGGACAAGCTGGTCGTTACGGGTAACGAGTTTGCGGCTTAA

Upstream 100 bases:

>100_bases
ACTGACCGGATTATCGGCCAAAACCTATCATTTTCTATAGTTATGAGGCGCAAGACGCCGCGCTATGGTGCCCCCAAACT
ATCCAGCAGGGACCGGCGAC

Downstream 100 bases:

>100_bases
CCATAAGCCCTCATTTGATCCGCCCCGGGAAGCCACGTCATTAGAGTTAATACTTCAGTAACGCTAATAGCGAAAGTTAA
CTTTATTGGTCGTACGACTG

Product: peptidase S33, tricorn interacting factor 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MADMTIKEGFAPFGDYQTWYRITGDLHGPGTPLVILHGGPGCTHDYVDAFKDIASTGRAVIHYDQLGNGKSTRLPHKGRD
FWTVDLFLSELDNLLAHLSIKNNYALLGQSWGGMLAAEHAVRQPAGLKALIIANSPADMLTWVNEANRLREDLPADVQAA
LLKHEEAGTLKDPEYLKASRAFYDRHVCRITPWPEEVKRTFDAIDADPTVYHAMNGPTEFHVIGTMKNWTIVDRLKLINV
PALLISGKYDEATPLVVKPYVDNVPDISWSVFEESSHMPHVEERMACMGCIAGFLDKLVVTGNEFAA

Sequences:

>Translated_307_residues
MADMTIKEGFAPFGDYQTWYRITGDLHGPGTPLVILHGGPGCTHDYVDAFKDIASTGRAVIHYDQLGNGKSTRLPHKGRD
FWTVDLFLSELDNLLAHLSIKNNYALLGQSWGGMLAAEHAVRQPAGLKALIIANSPADMLTWVNEANRLREDLPADVQAA
LLKHEEAGTLKDPEYLKASRAFYDRHVCRITPWPEEVKRTFDAIDADPTVYHAMNGPTEFHVIGTMKNWTIVDRLKLINV
PALLISGKYDEATPLVVKPYVDNVPDISWSVFEESSHMPHVEERMACMGCIAGFLDKLVVTGNEFAA
>Mature_306_residues
ADMTIKEGFAPFGDYQTWYRITGDLHGPGTPLVILHGGPGCTHDYVDAFKDIASTGRAVIHYDQLGNGKSTRLPHKGRDF
WTVDLFLSELDNLLAHLSIKNNYALLGQSWGGMLAAEHAVRQPAGLKALIIANSPADMLTWVNEANRLREDLPADVQAAL
LKHEEAGTLKDPEYLKASRAFYDRHVCRITPWPEEVKRTFDAIDADPTVYHAMNGPTEFHVIGTMKNWTIVDRLKLINVP
ALLISGKYDEATPLVVKPYVDNVPDISWSVFEESSHMPHVEERMACMGCIAGFLDKLVVTGNEFAA

Specific function: Hydrolyzes L-prolinamide, L-proline-p-nitroanilide, L- alaninamide, L-methioninamide, piperidine-2-carboxamide and piperazine-2-carboxamide. Has a much lower activity towards piperazine-2-tert-butylcarboxamide. Does not hydrolyze dipeptides and D-prolinam

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005945
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.5.1.101 [H]

Molecular weight: Translated: 34098; Mature: 33967

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADMTIKEGFAPFGDYQTWYRITGDLHGPGTPLVILHGGPGCTHDYVDAFKDIASTGRAV
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEE
IHYDQLGNGKSTRLPHKGRDFWTVDLFLSELDNLLAHLSIKNNYALLGQSWGGMLAAEHA
EEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHEEEECCCEEEEECCCCCHHHHHHH
VRQPAGLKALIIANSPADMLTWVNEANRLREDLPADVQAALLKHEEAGTLKDPEYLKASR
HCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHH
AFYDRHVCRITPWPEEVKRTFDAIDADPTVYHAMNGPTEFHVIGTMKNWTIVDRLKLINV
HHHHCCEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHCC
PALLISGKYDEATPLVVKPYVDNVPDISWSVFEESSHMPHVEERMACMGCIAGFLDKLVV
CEEEEECCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHEE
TGNEFAA
CCCCCCC
>Mature Secondary Structure 
ADMTIKEGFAPFGDYQTWYRITGDLHGPGTPLVILHGGPGCTHDYVDAFKDIASTGRAV
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEE
IHYDQLGNGKSTRLPHKGRDFWTVDLFLSELDNLLAHLSIKNNYALLGQSWGGMLAAEHA
EEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHEEEECCCEEEEECCCCCHHHHHHH
VRQPAGLKALIIANSPADMLTWVNEANRLREDLPADVQAALLKHEEAGTLKDPEYLKASR
HCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHH
AFYDRHVCRITPWPEEVKRTFDAIDADPTVYHAMNGPTEFHVIGTMKNWTIVDRLKLINV
HHHHCCEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHCC
PALLISGKYDEATPLVVKPYVDNVPDISWSVFEESSHMPHVEERMACMGCIAGFLDKLVV
CEEEEECCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHEE
TGNEFAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA