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The map label for this gene is atoS [H]

Identifier: 66047316

GI number: 66047316

Start: 4874589

End: 4876625

Strand: Direct

Name: atoS [H]

Synonym: Psyr_4089

Alternate gene names: 66047316

Gene position: 4874589-4876625 (Clockwise)

Preceding gene: 66047315

Following gene: 66047317

Centisome position: 79.99

GC content: 60.58

Gene sequence:

>2037_bases
ATGCCCTTGCGCCAACGCCTGGAAAACCTGCCCGTCGGCCAGAAACTGCTGGCCGCCCTGCTGGTCCTGATGACCACCGT
ACTGCTGGTCGCCAACCTGACCTTCATCAGCGCGGCCTATTACATCTCTCAGGAGGCGATGGCTCCGCAGGCCCTGCAGA
CCATCGGCCGGCTGATCAGCAGCGCCAATCTCAACGAGCGGGCCTTGTACTCGCCTGATGAGGCGCGCGCGCTGCTCAAG
GAGCTGAGAAGCTACGGGCCGTTGCGTGCCGCAGCCCTGTATGACAACAACGGCGAGCGGCTTGAACAGATGCATCAGGG
CGAAAGCCTTGAGCTGCCCAGACGCTTTAAAGACCTGGATAGCTGGCGCCTCACCGAATTTCGCAGCACGCAAGTCATCA
CCGTACCCAAAGGTGACGAGCCGCCAGGGCATCTGCTGCTGGTGGCCAGCAGCGAGCTGCCACCGGCGTTCTACACCGGC
ACGCTCACCGCCAGCCTGGGCATTCTGGTGTTCAGCGTGTTGCTGTGGCTGGTGGTGGCGCGGCAGATTCGCCGACTGAT
CACCGAGCCCATTTACCAACTGGAAGAATTGTCCCGGCAGGTGACCCGCGAAGAGAACTACGCACTGCGCGCAGAACCCG
GCAACGATGATGAAATCGGCAGTCTGGCCGAGGCGTTCAATACCATGCTGTCGCGTATCGAAGCGCGTGAACAGCAACTC
AAGCGCGCGCGCGACGACTCGCAGGAAGCCTACGATCAGGCCCAGGGGCTGGCCGAGGAAACCCGCCACACCAACCGCAA
GCTGGAGCTGGAAGTCCAGGTGCGCAGCAAGATCGAGAAGAAGCTCACCGGCTTTCAGAATTACCTCAACAGCATCATCG
ACTCGATGCCCTCGGCGATGATTGCGCTGGATGAACAGTTGTACGTCACCCAGTGGAATCAGGAAGCCACAGCACTGTCC
GGCACCACACTGGACGAAGCGCTGAACCAGCCGATCTTCCTGGCCTTCGAGCCGATGCGCTCGTTTCTGCCGCAGATCAA
GCACACCGTCGAGCGCCACAGCGTGACCAAGATCGAGCGCGTGACCTGGATCAAGAATGACGAGCCCCGCCACTACGCTC
TGACGTTCTACCCGTTGACTGGCGATGCCGGGCGCGGCGTGGTGATCCGGATCGATGACATCACCCAGCGCATATCGCTG
GAAGAAATGATGGTGCAGTCGGAAAAAATGCTGTCTGTCGGCGGTCTGGCAGCAGGCATGGCGCATGAGATCAACAACCC
GCTGGGCGCCATACTGCACAACGTACAGAACATACGTCGGCGGCTGTCCCCGGAACTGCCGAAGAACATCGAGCAGGCCG
AGGCCGACGGCATCGATCTGGCGCAGGTCAACCATTACCTGGAAAGCCGCGAAGTGCCGAAACTGCTCGACGGTATTCAA
CAGGCCGGTGCCAGGGCCGCAAAAATTGTCAGCCACATGCTCAATTTCAGCCGCCTGAGCAGTCGGCAGTTATCGCCCTG
CGACTTGCCGGCCTTGATCGATCAGGCCGTGGAGATCGCCAGTAACGACTTCGATCTGACCATCGGCTTCGACTTCAAGG
GTCAGCACATCATCCGTCAGTTCGACCCCGAACTGGGTCCGGTACCATGCATCGCCAACGAGCTGGAGCAGGTGCTGCTG
AACCTGCTGAAGAACGCCGCGCAGGCCATCCACCAGCGGCCGGAGAGCGAAGAGCCTGGGCGCATTACCCTGCGCACGCG
TCTCAATCCGCCGTGGGCCGAGATTCAGGTGGAGGACAATGGCATCGGCATGTCGGAGAGCATCCGCAAGCGTACGTTCG
AGCCGTTTTTCACCACCAAGGAAATCGGCCAGGGCACCGGGCTGGGTCTGTCGGTGTCCTACTTCATTGTCACCAACAAC
CACAAAGGCCAGATGGAGGTACATTCCTCTCTCGGCACAGGCACCTGCTTTACGCTGCGTCTACCGCTGGTGGCCAACCC
GGTCAGCGTTCAGCAGCAGGTCATTTCAAAATCCTGA

Upstream 100 bases:

>100_bases
ATTTGCAGACGCGTCTGACCGCTCATCTGGCAAGCAAGGGTTTGCGTACCGACTAGCCCGCGCTACCCTGCTCGCATTAC
CCGTCACTGCGACTTGCCCA

Downstream 100 bases:

>100_bases
TCAGGAATCGCATCAATGGGCTTTCGTTTGTCGAAGATTTACACGCGTACCGGCGATGCCGGTGAAACCGGTCTGGGCGA
TGGCCGACGCGTCTCCAAGG

Product: PAS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 677

Protein sequence:

>678_residues
MPLRQRLENLPVGQKLLAALLVLMTTVLLVANLTFISAAYYISQEAMAPQALQTIGRLISSANLNERALYSPDEARALLK
ELRSYGPLRAAALYDNNGERLEQMHQGESLELPRRFKDLDSWRLTEFRSTQVITVPKGDEPPGHLLLVASSELPPAFYTG
TLTASLGILVFSVLLWLVVARQIRRLITEPIYQLEELSRQVTREENYALRAEPGNDDEIGSLAEAFNTMLSRIEAREQQL
KRARDDSQEAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSAMIALDEQLYVTQWNQEATALS
GTTLDEALNQPIFLAFEPMRSFLPQIKHTVERHSVTKIERVTWIKNDEPRHYALTFYPLTGDAGRGVVIRIDDITQRISL
EEMMVQSEKMLSVGGLAAGMAHEINNPLGAILHNVQNIRRRLSPELPKNIEQAEADGIDLAQVNHYLESREVPKLLDGIQ
QAGARAAKIVSHMLNFSRLSSRQLSPCDLPALIDQAVEIASNDFDLTIGFDFKGQHIIRQFDPELGPVPCIANELEQVLL
NLLKNAAQAIHQRPESEEPGRITLRTRLNPPWAEIQVEDNGIGMSESIRKRTFEPFFTTKEIGQGTGLGLSVSYFIVTNN
HKGQMEVHSSLGTGTCFTLRLPLVANPVSVQQQVISKS

Sequences:

>Translated_678_residues
MPLRQRLENLPVGQKLLAALLVLMTTVLLVANLTFISAAYYISQEAMAPQALQTIGRLISSANLNERALYSPDEARALLK
ELRSYGPLRAAALYDNNGERLEQMHQGESLELPRRFKDLDSWRLTEFRSTQVITVPKGDEPPGHLLLVASSELPPAFYTG
TLTASLGILVFSVLLWLVVARQIRRLITEPIYQLEELSRQVTREENYALRAEPGNDDEIGSLAEAFNTMLSRIEAREQQL
KRARDDSQEAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSAMIALDEQLYVTQWNQEATALS
GTTLDEALNQPIFLAFEPMRSFLPQIKHTVERHSVTKIERVTWIKNDEPRHYALTFYPLTGDAGRGVVIRIDDITQRISL
EEMMVQSEKMLSVGGLAAGMAHEINNPLGAILHNVQNIRRRLSPELPKNIEQAEADGIDLAQVNHYLESREVPKLLDGIQ
QAGARAAKIVSHMLNFSRLSSRQLSPCDLPALIDQAVEIASNDFDLTIGFDFKGQHIIRQFDPELGPVPCIANELEQVLL
NLLKNAAQAIHQRPESEEPGRITLRTRLNPPWAEIQVEDNGIGMSESIRKRTFEPFFTTKEIGQGTGLGLSVSYFIVTNN
HKGQMEVHSSLGTGTCFTLRLPLVANPVSVQQQVISKS
>Mature_677_residues
PLRQRLENLPVGQKLLAALLVLMTTVLLVANLTFISAAYYISQEAMAPQALQTIGRLISSANLNERALYSPDEARALLKE
LRSYGPLRAAALYDNNGERLEQMHQGESLELPRRFKDLDSWRLTEFRSTQVITVPKGDEPPGHLLLVASSELPPAFYTGT
LTASLGILVFSVLLWLVVARQIRRLITEPIYQLEELSRQVTREENYALRAEPGNDDEIGSLAEAFNTMLSRIEAREQQLK
RARDDSQEAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSAMIALDEQLYVTQWNQEATALSG
TTLDEALNQPIFLAFEPMRSFLPQIKHTVERHSVTKIERVTWIKNDEPRHYALTFYPLTGDAGRGVVIRIDDITQRISLE
EMMVQSEKMLSVGGLAAGMAHEINNPLGAILHNVQNIRRRLSPELPKNIEQAEADGIDLAQVNHYLESREVPKLLDGIQQ
AGARAAKIVSHMLNFSRLSSRQLSPCDLPALIDQAVEIASNDFDLTIGFDFKGQHIIRQFDPELGPVPCIANELEQVLLN
LLKNAAQAIHQRPESEEPGRITLRTRLNPPWAEIQVEDNGIGMSESIRKRTFEPFFTTKEIGQGTGLGLSVSYFIVTNNH
KGQMEVHSSLGTGTCFTLRLPLVANPVSVQQQVISKS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=31.3984168865435, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1790436, Length=265, Percent_Identity=32.0754716981132, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI145693157, Length=295, Percent_Identity=27.4576271186441, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790300, Length=286, Percent_Identity=28.3216783216783, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=429, Percent_Identity=22.3776223776224, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76002; Mature: 75871

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRQRLENLPVGQKLLAALLVLMTTVLLVANLTFISAAYYISQEAMAPQALQTIGRLIS
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SANLNERALYSPDEARALLKELRSYGPLRAAALYDNNGERLEQMHQGESLELPRRFKDLD
CCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCCCCHHHHCCC
SWRLTEFRSTQVITVPKGDEPPGHLLLVASSELPPAFYTGTLTASLGILVFSVLLWLVVA
CCHHHHCCCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQIRRLITEPIYQLEELSRQVTREENYALRAEPGNDDEIGSLAEAFNTMLSRIEAREQQL
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KRARDDSQEAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSAM
HHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IALDEQLYVTQWNQEATALSGTTLDEALNQPIFLAFEPMRSFLPQIKHTVERHSVTKIER
HHHCCCCEEEECCCCHHHCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
VTWIKNDEPRHYALTFYPLTGDAGRGVVIRIDDITQRISLEEMMVQSEKMLSVGGLAAGM
HHEECCCCCCEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHEINNPLGAILHNVQNIRRRLSPELPKNIEQAEADGIDLAQVNHYLESREVPKLLDGIQ
HHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHH
QAGARAAKIVSHMLNFSRLSSRQLSPCDLPALIDQAVEIASNDFDLTIGFDFKGQHIIRQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
FDPELGPVPCIANELEQVLLNLLKNAAQAIHQRPESEEPGRITLRTRLNPPWAEIQVEDN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEECCC
GIGMSESIRKRTFEPFFTTKEIGQGTGLGLSVSYFIVTNNHKGQMEVHSSLGTGTCFTLR
CCCCHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEEEEECCCCCCCHHHCCCCCCEEEEEE
LPLVANPVSVQQQVISKS
CCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
PLRQRLENLPVGQKLLAALLVLMTTVLLVANLTFISAAYYISQEAMAPQALQTIGRLIS
CHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SANLNERALYSPDEARALLKELRSYGPLRAAALYDNNGERLEQMHQGESLELPRRFKDLD
CCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCCCCHHHHCCC
SWRLTEFRSTQVITVPKGDEPPGHLLLVASSELPPAFYTGTLTASLGILVFSVLLWLVVA
CCHHHHCCCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQIRRLITEPIYQLEELSRQVTREENYALRAEPGNDDEIGSLAEAFNTMLSRIEAREQQL
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KRARDDSQEAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSAM
HHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IALDEQLYVTQWNQEATALSGTTLDEALNQPIFLAFEPMRSFLPQIKHTVERHSVTKIER
HHHCCCCEEEECCCCHHHCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
VTWIKNDEPRHYALTFYPLTGDAGRGVVIRIDDITQRISLEEMMVQSEKMLSVGGLAAGM
HHEECCCCCCEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHEINNPLGAILHNVQNIRRRLSPELPKNIEQAEADGIDLAQVNHYLESREVPKLLDGIQ
HHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHH
QAGARAAKIVSHMLNFSRLSSRQLSPCDLPALIDQAVEIASNDFDLTIGFDFKGQHIIRQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
FDPELGPVPCIANELEQVLLNLLKNAAQAIHQRPESEEPGRITLRTRLNPPWAEIQVEDN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEECCC
GIGMSESIRKRTFEPFFTTKEIGQGTGLGLSVSYFIVTNNHKGQMEVHSSLGTGTCFTLR
CCCCHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEEEEECCCCCCCHHHCCCCCCEEEEEE
LPLVANPVSVQQQVISKS
CCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]