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The map label for this gene is grxD [H]

Identifier: 66047125

GI number: 66047125

Start: 4638806

End: 4639132

Strand: Reverse

Name: grxD [H]

Synonym: Psyr_3898

Alternate gene names: 66047125

Gene position: 4639132-4638806 (Counterclockwise)

Preceding gene: 66047126

Following gene: 66047120

Centisome position: 76.13

GC content: 53.82

Gene sequence:

>327_bases
ATGGATATCATCGAAACGATTAAAGAGCAGATTGCCAACAACACCATTCTGCTTTACATGAAAGGCGCTCCGAACGCTCC
GCAATGCGGCTTTTCGGCCAAGGCTTCCCAGGCATTGATGGCGTGTGGCGAAAAGTTTGCCTACGTCGACATTCTGCAAA
ACCCTGAAATCCGCGCCAACCTGCCAAAGTACGCCAACTGGCCGACTTTCCCGCAACTGTGGGTTGCCGGTGAGCTGGTC
GGTGGTAGCGACATCATCACCGAGATGATGGATGACGGTTCGTTGCAGACGTTGGTCAAGGAAGCATCCGCCGCCAAGGC
TGAGTAA

Upstream 100 bases:

>100_bases
GTGGCGTGTTAAGCCTCAAGACAGAGCGTCATGCTCGGGATTTCGTTACAATGTGTCACCGTGCCGACAACTGAGTCGGA
TATTTCAGCCGAGGTGCTCC

Downstream 100 bases:

>100_bases
AGCCTTGCGCAGAGCGTCGCACGATAGTCGAGATTATCGTTCCCTGCGCTCCAGCATGGTTTTACACACAAGAAAAAGCC
CGCTCTCGATTGAGGCGGGC

Product: glutaredoxin-like protein

Products: NA

Alternate protein names: Grx4; Monothiol glutaredoxin [H]

Number of amino acids: Translated: 108; Mature: 108

Protein sequence:

>108_residues
MDIIETIKEQIANNTILLYMKGAPNAPQCGFSAKASQALMACGEKFAYVDILQNPEIRANLPKYANWPTFPQLWVAGELV
GGSDIITEMMDDGSLQTLVKEASAAKAE

Sequences:

>Translated_108_residues
MDIIETIKEQIANNTILLYMKGAPNAPQCGFSAKASQALMACGEKFAYVDILQNPEIRANLPKYANWPTFPQLWVAGELV
GGSDIITEMMDDGSLQTLVKEASAAKAE
>Mature_108_residues
MDIIETIKEQIANNTILLYMKGAPNAPQCGFSAKASQALMACGEKFAYVDILQNPEIRANLPKYANWPTFPQLWVAGELV
GGSDIITEMMDDGSLQTLVKEASAAKAE

Specific function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters [H]

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI95113651, Length=96, Percent_Identity=39.5833333333333, Blast_Score=86, Evalue=9e-18,
Organism=Homo sapiens, GI42516576, Length=92, Percent_Identity=38.0434782608696, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787943, Length=101, Percent_Identity=73.2673267326733, Blast_Score=160, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71988153, Length=82, Percent_Identity=40.2439024390244, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988159, Length=82, Percent_Identity=40.2439024390244, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17556042, Length=95, Percent_Identity=32.6315789473684, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325198, Length=106, Percent_Identity=39.622641509434, Blast_Score=88, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320303, Length=77, Percent_Identity=44.1558441558442, Blast_Score=87, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6321022, Length=77, Percent_Identity=42.8571428571429, Blast_Score=86, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24642023, Length=97, Percent_Identity=38.1443298969072, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI19921242, Length=96, Percent_Identity=37.5, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 11722; Mature: 11722

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIETIKEQIANNTILLYMKGAPNAPQCGFSAKASQALMACGEKFAYVDILQNPEIRAN
CCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCC
LPKYANWPTFPQLWVAGELVGGSDIITEMMDDGSLQTLVKEASAAKAE
CCCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIIETIKEQIANNTILLYMKGAPNAPQCGFSAKASQALMACGEKFAYVDILQNPEIRAN
CCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCC
LPKYANWPTFPQLWVAGELVGGSDIITEMMDDGSLQTLVKEASAAKAE
CCCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]