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The map label for this gene is foxA [H]

Identifier: 66046574

GI number: 66046574

Start: 4000347

End: 4002464

Strand: Direct

Name: foxA [H]

Synonym: Psyr_3345

Alternate gene names: 66046574

Gene position: 4000347-4002464 (Clockwise)

Preceding gene: 66046573

Following gene: 66046576

Centisome position: 65.65

GC content: 59.44

Gene sequence:

>2118_bases
TTGAGCACTTCCTTCCAATGCCCTCGCCGTCCCGGCTCTTTTCTGCTGTCCGCGCTTTCTCTGGCGATGTTCTCCGGCGG
CGCAGTGCATGCTGCCGAAACCGCAACGCTGCCCGCTACGCAGGTGTCGGCAACCGCGACCGAAGCGCAGGAAGGCTACA
GCGCCAAAAGCGCCAGCACTGCGAGCAAGAGTGACGTACCGCTCAAGGAAGAAGCGCAGTCGGTCAACGTGGTGACACCG
CAAACCATCGCCGACTACAACGTGCGCTCGCTGGACGATGCCATGAAGTTTGTCAGTGGTGTCAGCCAGGGCAATACCCT
TGGCAATACCAAGGACTCGCTGGTCAAGCGCGGCTTTGGCACCAACGATGATGGCTCGGTGCTGCGTGACGGCGTGCGCT
CGGTGATGTCGAAAAATTTCGGTGCCACTACCGAACGCGTTGAAGTGCTCAAAGGCCCGGCCTCGCTGCTGTACGGGGCG
ATGGAGCCGGGTGGCGTGATCAATGTGATCAGCAAACAGCCGCAATACGTGCAAAGCACCACGCTCAGTGGCTCGGCGTA
CAGCGAAGGCGGCGGCAGCTTCGGCATCGACACCACCGGCCCGCTGGGTGACTCGGGGCTGGCCTACCGCCTGGTGGCCG
AGCGTCAGAGCGAGGACTACTGGCGTAACTATGGCGTTGACCAGCACACGCTGGTCGCGCCGTCGCTGTCCTGGACCGGG
GAGCGCGCCAGCCTGACGCTGGCTTACGAGTACAACGATTACGTCAGCCCGTTCGATCGTGGCACGGTGTTCACCGGCGG
TCATCCGGCCGATATCAGCTACGACAAGCGCCTGGACGAAAAATGGGCAAATACGGTCGGCATCAGCGAAACCGCTACCG
CACGCTTCGAGTACCAGCTCAGCGATGACTGGAAAACCCGCCTGACCTACGGCTGGAACAACGACCGCTACAGCCTCTCG
ATTGCCCAGCCGAGCACGCTGTCCAGCAGCGGCGTGCTGCGACGCCAGGCCAATGGCGGCCATTACGATTATGAAACGCG
TTATGCCAGCTGGGACTTCATCGGCAAGCAGGAGGTGTTTGGCCAGCAACATGATCTGCTGATCGGTGCCGAGCAGGAGG
ATTCCGACAAGTACCGCGGCAAGACTTACCGCAATGGCGTACAGGGTGGCTTCAATATCTTTTCGCCCAGCTACGGCAGC
CTGGCGGAGCCCAGTGTTGTCAGTACGACCACCAGCAACCTGAGCAATCAACTGACCTCATCGTCCATCTACCTCAAGGA
CAACTGGCATCTTGATGACCGCTGGATTCTGGTCCTGGGCGGCCGCTATCAGCATTATGACCAGCACATCGCCCAAGGCC
TCGGCGCCAGCCGCAACACTAATCTGAACAAAAATGACGATATATTCCTGCCGATGGCGGGACTGGTATTCAAGGTCAAT
GAGGACCTGTCGTTGTACGGCAACTACAGCCGCTCTTTCGTCCCCAATGAGGCGGTTAACGATGACGGCACCACCTTCGA
CCCGGAAGAAGGCCGCAGCTACGAAGTCGGCGCCAAATATGCGCTGGCACCGGAACTCGACTTCAACCTCGCCGTGTTTG
ACATAGAGAAGAAAAATGTTGTGACCACCGTTGCTACCGGCGTCAGCGAAGCGGCTGGCAAAGTGGGTTCACAGGGCGTG
GAGCTGGACGTGACCGGTCGAATTGCCGAGCGCTGGGACATGATCGGCACTTATGCCTACACACATACCGAAGTGCTTGA
TGACCCCAAAAACGAGGGCAACCGTTTGAGTCAGGCACCGAAACATACCGCCAGCCTGTATCTCACCCATCACCTGCAAG
TCCCGTCCGGTCTGGGCGAATGGCATGCCGGTGGTGGCGCGCGCTATGTCGGCGATAGGGCGGGTGACAACGCAAACACG
TTCTACATGAGCAGCTACACCGTGGCTGATGCGTTCCTGCGCTGGGATGTGCCAATGGCAGGTTATAAAACCCGCCTTCA
ATTGAACGTGGATAACCTGTTCGACAAGCAGTACTACCCGTCCAGTACCGACAGCCCGTTGCAGGTCAATGTGGGTGAAC
CACGCACCGCACGCCTGAGCGCCAGCGTCACGTTCTAA

Upstream 100 bases:

>100_bases
CGAGGCGACCGAAACCATCGGGCGCCTCAATCATTTATTTACATGAGAATTAATATCAAATTACAATTATTGCTATTAAC
GTCCTAGCAGAGCATCTCCC

Downstream 100 bases:

>100_bases
GAGGTTGCCACGAAGCAGGCCTGCGCGGGCTTGCTCCGTGGGCAATCAAACGGATGAATCAGAACTTCATTCGGTAAAAA
CTGATCAGCGCTTCATTGCC

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 704

Protein sequence:

>705_residues
MSTSFQCPRRPGSFLLSALSLAMFSGGAVHAAETATLPATQVSATATEAQEGYSAKSASTASKSDVPLKEEAQSVNVVTP
QTIADYNVRSLDDAMKFVSGVSQGNTLGNTKDSLVKRGFGTNDDGSVLRDGVRSVMSKNFGATTERVEVLKGPASLLYGA
MEPGGVINVISKQPQYVQSTTLSGSAYSEGGGSFGIDTTGPLGDSGLAYRLVAERQSEDYWRNYGVDQHTLVAPSLSWTG
ERASLTLAYEYNDYVSPFDRGTVFTGGHPADISYDKRLDEKWANTVGISETATARFEYQLSDDWKTRLTYGWNNDRYSLS
IAQPSTLSSSGVLRRQANGGHYDYETRYASWDFIGKQEVFGQQHDLLIGAEQEDSDKYRGKTYRNGVQGGFNIFSPSYGS
LAEPSVVSTTTSNLSNQLTSSSIYLKDNWHLDDRWILVLGGRYQHYDQHIAQGLGASRNTNLNKNDDIFLPMAGLVFKVN
EDLSLYGNYSRSFVPNEAVNDDGTTFDPEEGRSYEVGAKYALAPELDFNLAVFDIEKKNVVTTVATGVSEAAGKVGSQGV
ELDVTGRIAERWDMIGTYAYTHTEVLDDPKNEGNRLSQAPKHTASLYLTHHLQVPSGLGEWHAGGGARYVGDRAGDNANT
FYMSSYTVADAFLRWDVPMAGYKTRLQLNVDNLFDKQYYPSSTDSPLQVNVGEPRTARLSASVTF

Sequences:

>Translated_705_residues
MSTSFQCPRRPGSFLLSALSLAMFSGGAVHAAETATLPATQVSATATEAQEGYSAKSASTASKSDVPLKEEAQSVNVVTP
QTIADYNVRSLDDAMKFVSGVSQGNTLGNTKDSLVKRGFGTNDDGSVLRDGVRSVMSKNFGATTERVEVLKGPASLLYGA
MEPGGVINVISKQPQYVQSTTLSGSAYSEGGGSFGIDTTGPLGDSGLAYRLVAERQSEDYWRNYGVDQHTLVAPSLSWTG
ERASLTLAYEYNDYVSPFDRGTVFTGGHPADISYDKRLDEKWANTVGISETATARFEYQLSDDWKTRLTYGWNNDRYSLS
IAQPSTLSSSGVLRRQANGGHYDYETRYASWDFIGKQEVFGQQHDLLIGAEQEDSDKYRGKTYRNGVQGGFNIFSPSYGS
LAEPSVVSTTTSNLSNQLTSSSIYLKDNWHLDDRWILVLGGRYQHYDQHIAQGLGASRNTNLNKNDDIFLPMAGLVFKVN
EDLSLYGNYSRSFVPNEAVNDDGTTFDPEEGRSYEVGAKYALAPELDFNLAVFDIEKKNVVTTVATGVSEAAGKVGSQGV
ELDVTGRIAERWDMIGTYAYTHTEVLDDPKNEGNRLSQAPKHTASLYLTHHLQVPSGLGEWHAGGGARYVGDRAGDNANT
FYMSSYTVADAFLRWDVPMAGYKTRLQLNVDNLFDKQYYPSSTDSPLQVNVGEPRTARLSASVTF
>Mature_704_residues
STSFQCPRRPGSFLLSALSLAMFSGGAVHAAETATLPATQVSATATEAQEGYSAKSASTASKSDVPLKEEAQSVNVVTPQ
TIADYNVRSLDDAMKFVSGVSQGNTLGNTKDSLVKRGFGTNDDGSVLRDGVRSVMSKNFGATTERVEVLKGPASLLYGAM
EPGGVINVISKQPQYVQSTTLSGSAYSEGGGSFGIDTTGPLGDSGLAYRLVAERQSEDYWRNYGVDQHTLVAPSLSWTGE
RASLTLAYEYNDYVSPFDRGTVFTGGHPADISYDKRLDEKWANTVGISETATARFEYQLSDDWKTRLTYGWNNDRYSLSI
AQPSTLSSSGVLRRQANGGHYDYETRYASWDFIGKQEVFGQQHDLLIGAEQEDSDKYRGKTYRNGVQGGFNIFSPSYGSL
AEPSVVSTTTSNLSNQLTSSSIYLKDNWHLDDRWILVLGGRYQHYDQHIAQGLGASRNTNLNKNDDIFLPMAGLVFKVNE
DLSLYGNYSRSFVPNEAVNDDGTTFDPEEGRSYEVGAKYALAPELDFNLAVFDIEKKNVVTTVATGVSEAAGKVGSQGVE
LDVTGRIAERWDMIGTYAYTHTEVLDDPKNEGNRLSQAPKHTASLYLTHHLQVPSGLGEWHAGGGARYVGDRAGDNANTF
YMSSYTVADAFLRWDVPMAGYKTRLQLNVDNLFDKQYYPSSTDSPLQVNVGEPRTARLSASVTF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=755, Percent_Identity=24.3708609271523, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786344, Length=280, Percent_Identity=32.8571428571429, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787024, Length=733, Percent_Identity=25.9208731241473, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1787723, Length=707, Percent_Identity=24.8939179632249, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790743, Length=332, Percent_Identity=24.0963855421687, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76908; Mature: 76777

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSFQCPRRPGSFLLSALSLAMFSGGAVHAAETATLPATQVSATATEAQEGYSAKSAST
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCHHCCHHHHHHHHCCCCCCCCC
ASKSDVPLKEEAQSVNVVTPQTIADYNVRSLDDAMKFVSGVSQGNTLGNTKDSLVKRGFG
CCCCCCCCHHHHCCCEEECCCHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
TNDDGSVLRDGVRSVMSKNFGATTERVEVLKGPASLLYGAMEPGGVINVISKQPQYVQST
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHCCCCCCCCEEEECCCCCCHHHHE
TLSGSAYSEGGGSFGIDTTGPLGDSGLAYRLVAERQSEDYWRNYGVDQHTLVAPSLSWTG
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCCCEEEECCCCCCC
ERASLTLAYEYNDYVSPFDRGTVFTGGHPADISYDKRLDEKWANTVGISETATARFEYQL
CCEEEEEEEECCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
SDDWKTRLTYGWNNDRYSLSIAQPSTLSSSGVLRRQANGGHYDYETRYASWDFIGKQEVF
CCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCCCCCCCEECCCCCCCHHHHC
GQQHDLLIGAEQEDSDKYRGKTYRNGVQGGFNIFSPSYGSLAEPSVVSTTTSNLSNQLTS
CCCCCEEEECCCCCCHHHCCCHHHCCCCCCCEECCCCCCCCCCCCEEEEHHHHHHHHHCC
SSIYLKDNWHLDDRWILVLGGRYQHYDQHIAQGLGASRNTNLNKNDDIFLPMAGLVFKVN
CEEEEEECCEECCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEEC
EDLSLYGNYSRSFVPNEAVNDDGTTFDPEEGRSYEVGAKYALAPELDFNLAVFDIEKKNV
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEECCCCCCEEEEEEECCCCE
VTTVATGVSEAAGKVGSQGVELDVTGRIAERWDMIGTYAYTHTEVLDDPKNEGNRLSQAP
EEEEHHCHHHHHHHCCCCCEEEEECCCHHHHHHHHEEEEEEEHHHHCCCCCCCCHHHCCC
KHTASLYLTHHLQVPSGLGEWHAGGGARYVGDRAGDNANTFYMSSYTVADAFLRWDVPMA
CCCEEEEEEEEEECCCCCCCCCCCCCCEECCCCCCCCCCEEEEECHHHHHHHHEECCCCC
GYKTRLQLNVDNLFDKQYYPSSTDSPLQVNVGEPRTARLSASVTF
CCEEEEEEEHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEECC
>Mature Secondary Structure 
STSFQCPRRPGSFLLSALSLAMFSGGAVHAAETATLPATQVSATATEAQEGYSAKSAST
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCHHCCHHHHHHHHCCCCCCCCC
ASKSDVPLKEEAQSVNVVTPQTIADYNVRSLDDAMKFVSGVSQGNTLGNTKDSLVKRGFG
CCCCCCCCHHHHCCCEEECCCHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
TNDDGSVLRDGVRSVMSKNFGATTERVEVLKGPASLLYGAMEPGGVINVISKQPQYVQST
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHCCCCCCCCEEEECCCCCCHHHHE
TLSGSAYSEGGGSFGIDTTGPLGDSGLAYRLVAERQSEDYWRNYGVDQHTLVAPSLSWTG
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCCCEEEECCCCCCC
ERASLTLAYEYNDYVSPFDRGTVFTGGHPADISYDKRLDEKWANTVGISETATARFEYQL
CCEEEEEEEECCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
SDDWKTRLTYGWNNDRYSLSIAQPSTLSSSGVLRRQANGGHYDYETRYASWDFIGKQEVF
CCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCCCCCCCEECCCCCCCHHHHC
GQQHDLLIGAEQEDSDKYRGKTYRNGVQGGFNIFSPSYGSLAEPSVVSTTTSNLSNQLTS
CCCCCEEEECCCCCCHHHCCCHHHCCCCCCCEECCCCCCCCCCCCEEEEHHHHHHHHHCC
SSIYLKDNWHLDDRWILVLGGRYQHYDQHIAQGLGASRNTNLNKNDDIFLPMAGLVFKVN
CEEEEEECCEECCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEEC
EDLSLYGNYSRSFVPNEAVNDDGTTFDPEEGRSYEVGAKYALAPELDFNLAVFDIEKKNV
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEECCCCCCEEEEEEECCCCE
VTTVATGVSEAAGKVGSQGVELDVTGRIAERWDMIGTYAYTHTEVLDDPKNEGNRLSQAP
EEEEHHCHHHHHHHCCCCCEEEEECCCHHHHHHHHEEEEEEEHHHHCCCCCCCCHHHCCC
KHTASLYLTHHLQVPSGLGEWHAGGGARYVGDRAGDNANTFYMSSYTVADAFLRWDVPMA
CCCEEEEEEEEEECCCCCCCCCCCCCCEECCCCCCCCCCEEEEECHHHHHHHHEECCCCC
GYKTRLQLNVDNLFDKQYYPSSTDSPLQVNVGEPRTARLSASVTF
CCEEEEEEEHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]