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The map label for this gene is yfhR [C]

Identifier: 66046573

GI number: 66046573

Start: 3999241

End: 4000131

Strand: Direct

Name: yfhR [C]

Synonym: Psyr_3344

Alternate gene names: 66046573

Gene position: 3999241-4000131 (Clockwise)

Preceding gene: 66046568

Following gene: 66046574

Centisome position: 65.63

GC content: 59.37

Gene sequence:

>891_bases
ATGACAACCATCATTCTTGGCCTGCCCGTCGGCTGTGCAGTGCTTGAACACAAGGAGCGCCAACTGGTGTTTCGCATCGA
GCCCGGTACCGCCAGCTGGTACAGCGGTCTGCCGGCAGATGTGCAGGAAATCGAACTCAGTACACCGGCATTCGGTACCT
CGCAGAATATCCACGCATGGTGGTGGCCCGCTGCGGACAAGAACGCCCCGGCGGTGTTGTACCTGCATGGATCACGATGG
AACCTCACCGGCCAGCTGTTCCGTATCCAGCAACTCAAGGCACAGGGCTACTCGATACTGGCGATCGATTACCGGGGTTT
CGGGCAAAGCATGGGCCAACTGCCTTCGGAAAGGTCTGTATATGAAGACGCACGCATCGCCTGGGAACGCCTGAAGCAAT
TGCAACCCGACCCGCAGCGCAGGCTGATTTATGGACACTCTCTGGGCGGTGCGGTGGCAGTGGATCTGGCTGCCGAGCTG
GGCGAAGACGCTGAAAAGGACAATGCACCCATTCAGGCCCGCGGGCTGATCATCGAATCCACGTTCACCAACCTCGCCGA
TGTGGCCACCGCGCTTGCCAACACATCGTTGCCGGTGCGTTGGCTGCTGTCGCAGAAGTTCGACTCGCTGGACAAGATTG
CAGACATCCATATGCCGGTGCTGATCGTGCACGGCACCGAGGATCGCTATGTACCGGCACGCTTCAGCGAACAGTTGTTT
GAGGCCGCGCAGGAACCGAAGAAACTGCTACTGGTGCCTGGCGGTACGCATAACAACAGCATGCAGCTCGGGCAGCCCGC
TTACAGCCAGGCCATTCGTGCCCTGCTCGATACACCCGCATCGCTGCCTCAGGTAACACAACAGGGCAAGGACTCGAAGA
ACGCCGGTTAG

Upstream 100 bases:

>100_bases
GCAGATTCTGCATTTATTTCACTTTGTTGACCGGACTATTCCTTTTATGTCGATTTCGCCACTGGCTCGCTTCAAAGCCC
GTCCGCTCAGGTGGGTTTGC

Downstream 100 bases:

>100_bases
ACATTGCCGGGCACGTGGCAGTAGTCTTCGGACTCATGGTCAAAGGACCCTGCATGGGCAAGCGGATCGATGCCAACGTA
ACGGCTCAGTCCTGAGCTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTTIILGLPVGCAVLEHKERQLVFRIEPGTASWYSGLPADVQEIELSTPAFGTSQNIHAWWWPAADKNAPAVLYLHGSRW
NLTGQLFRIQQLKAQGYSILAIDYRGFGQSMGQLPSERSVYEDARIAWERLKQLQPDPQRRLIYGHSLGGAVAVDLAAEL
GEDAEKDNAPIQARGLIIESTFTNLADVATALANTSLPVRWLLSQKFDSLDKIADIHMPVLIVHGTEDRYVPARFSEQLF
EAAQEPKKLLLVPGGTHNNSMQLGQPAYSQAIRALLDTPASLPQVTQQGKDSKNAG

Sequences:

>Translated_296_residues
MTTIILGLPVGCAVLEHKERQLVFRIEPGTASWYSGLPADVQEIELSTPAFGTSQNIHAWWWPAADKNAPAVLYLHGSRW
NLTGQLFRIQQLKAQGYSILAIDYRGFGQSMGQLPSERSVYEDARIAWERLKQLQPDPQRRLIYGHSLGGAVAVDLAAEL
GEDAEKDNAPIQARGLIIESTFTNLADVATALANTSLPVRWLLSQKFDSLDKIADIHMPVLIVHGTEDRYVPARFSEQLF
EAAQEPKKLLLVPGGTHNNSMQLGQPAYSQAIRALLDTPASLPQVTQQGKDSKNAG
>Mature_295_residues
TTIILGLPVGCAVLEHKERQLVFRIEPGTASWYSGLPADVQEIELSTPAFGTSQNIHAWWWPAADKNAPAVLYLHGSRWN
LTGQLFRIQQLKAQGYSILAIDYRGFGQSMGQLPSERSVYEDARIAWERLKQLQPDPQRRLIYGHSLGGAVAVDLAAELG
EDAEKDNAPIQARGLIIESTFTNLADVATALANTSLPVRWLLSQKFDSLDKIADIHMPVLIVHGTEDRYVPARFSEQLFE
AAQEPKKLLLVPGGTHNNSMQLGQPAYSQAIRALLDTPASLPQVTQQGKDSKNAG

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=201, Percent_Identity=30.8457711442786, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32451492, Length=238, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI32528310, Length=267, Percent_Identity=26.5917602996255, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI71051602, Length=240, Percent_Identity=31.25, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI71051600, Length=240, Percent_Identity=31.25, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI24308097, Length=200, Percent_Identity=31, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI109689718, Length=200, Percent_Identity=31, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI151301175, Length=191, Percent_Identity=28.7958115183246, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI194306562, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI194306564, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI226510965, Length=207, Percent_Identity=28.5024154589372, Blast_Score=101, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71988362, Length=220, Percent_Identity=30, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17566318, Length=201, Percent_Identity=25.3731343283582, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17532877, Length=160, Percent_Identity=30.625, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71985392, Length=161, Percent_Identity=30.4347826086957, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17137566, Length=229, Percent_Identity=31.0043668122271, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281362521, Length=225, Percent_Identity=27.1111111111111, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281362519, Length=225, Percent_Identity=27.1111111111111, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571878, Length=225, Percent_Identity=27.1111111111111, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24655467, Length=187, Percent_Identity=31.0160427807487, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24655464, Length=187, Percent_Identity=31.0160427807487, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 32573; Mature: 32442

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIILGLPVGCAVLEHKERQLVFRIEPGTASWYSGLPADVQEIELSTPAFGTSQNIHAW
CCEEEEECCCHHHHHHCCCCEEEEEECCCCCHHHCCCCCCHHHEEECCCCCCCCCCCEEE
WWPAADKNAPAVLYLHGSRWNLTGQLFRIQQLKAQGYSILAIDYRGFGQSMGQLPSERSV
ECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCHH
YEDARIAWERLKQLQPDPQRRLIYGHSLGGAVAVDLAAELGEDAEKDNAPIQARGLIIES
HHHHHHHHHHHHHCCCCHHHEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEH
TFTNLADVATALANTSLPVRWLLSQKFDSLDKIADIHMPVLIVHGTEDRYVPARFSEQLF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECHHHHHHHH
EAAQEPKKLLLVPGGTHNNSMQLGQPAYSQAIRALLDTPASLPQVTQQGKDSKNAG
HHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTIILGLPVGCAVLEHKERQLVFRIEPGTASWYSGLPADVQEIELSTPAFGTSQNIHAW
CEEEEECCCHHHHHHCCCCEEEEEECCCCCHHHCCCCCCHHHEEECCCCCCCCCCCEEE
WWPAADKNAPAVLYLHGSRWNLTGQLFRIQQLKAQGYSILAIDYRGFGQSMGQLPSERSV
ECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCHH
YEDARIAWERLKQLQPDPQRRLIYGHSLGGAVAVDLAAELGEDAEKDNAPIQARGLIIES
HHHHHHHHHHHHHCCCCHHHEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEH
TFTNLADVATALANTSLPVRWLLSQKFDSLDKIADIHMPVLIVHGTEDRYVPARFSEQLF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECHHHHHHHH
EAAQEPKKLLLVPGGTHNNSMQLGQPAYSQAIRALLDTPASLPQVTQQGKDSKNAG
HHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]