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The map label for this gene is gsiC [H]

Identifier: 66045506

GI number: 66045506

Start: 2631260

End: 2632177

Strand: Reverse

Name: gsiC [H]

Synonym: Psyr_2266

Alternate gene names: 66045506

Gene position: 2632177-2631260 (Counterclockwise)

Preceding gene: 66045507

Following gene: 66045505

Centisome position: 43.2

GC content: 61.87

Gene sequence:

>918_bases
ATGTTCGGATTTCTCTTGCGCCGCCTGGGTATTGCCCTGTGCGTAGCGATTACCGTGTCGGTGATCAGCTTTTCCCTGCT
GCACCTGTCCGGCGATCTGGCCACTGCCATCGGTGGGCCGGAAGCCAGCAGCGAGCAGATCGAACAGATCCGCGTGCAGT
ACGGCCTCAACAAGCCGTTGGTTACGCAGTATTTCGAATGGCTGGCCGACGTGGTGCGTCTTGATCTGGGCGACTCGTTC
TTCTTTCAGGAGTCGGTCTACAACCTGATCGCCTCACGGCTGTCGATCACCCTCGGGCTGGGTGCGATGGCCCTGAGTAT
TGCGCTGCTGATCGCCATTCCGCTGGGCGTGCTGGCCGCGGTGAAACGTGACACGTGGATTGATCGCCTGGCACTGAGCA
TCGCAGTACTGGGTCAGGCCATGCCGAGTTTCTGGTTCGCACTGATGCTGATCGTGGTGTTTTCGGTCACCCTGAAATGG
CTGCCGGTATCCGGCAATTCGACCTGGGCGCACTTCGTGATGCCGGCCATCGCCCTCGGTTATTACGCCACGCCGGCGAT
CATGCGCCTGACCCGTGCGGGCATGCTCGACGTGCTCAACTCCGATTACATCCGCACCGCACGAGCCAAGGGCCTGCGCC
CTGCCACCGTGCTGTTCAAGCATGCGCTGCGCAACGCGCTGATTCCGGTGGTGGCCCTCGCCGCCGTGGAATTCGGTTTC
ATGCTCGGCGGTTCGGTGGTCATCGAGACGGTTTTCTCGCTGCAGGGCATTGGCCAGCTGGCCTGGGACGCAATTGCCCG
TGACGACTTCCCGGTGGTGCAGGCGGTCGTGCTGTTGATCGCGGTGATCTACATCGTCCTCACCCTGCTGGCCGACGTGC
TCAACGCACTGCTCGACCCGCGCATCCGCGTGAAATAG

Upstream 100 bases:

>100_bases
ACTTGCCCAAGCCAGTCGGCCAGCCTGGCTGTAAGGCGCATGCCGCGCCTTGCAGCAGGGTCAGCCACGCCGTCATTCCC
TGAACACAAGGTCACTTGCC

Downstream 100 bases:

>100_bases
GAGGCCCCATGAGCACAACCACCTCATCGCCGCTGCTGATCAACGATTACCAGCCTCCGGCGCGCAGCGTCTGGCGCACG
TTACGCAGCAGCTTTGCGCA

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MFGFLLRRLGIALCVAITVSVISFSLLHLSGDLATAIGGPEASSEQIEQIRVQYGLNKPLVTQYFEWLADVVRLDLGDSF
FFQESVYNLIASRLSITLGLGAMALSIALLIAIPLGVLAAVKRDTWIDRLALSIAVLGQAMPSFWFALMLIVVFSVTLKW
LPVSGNSTWAHFVMPAIALGYYATPAIMRLTRAGMLDVLNSDYIRTARAKGLRPATVLFKHALRNALIPVVALAAVEFGF
MLGGSVVIETVFSLQGIGQLAWDAIARDDFPVVQAVVLLIAVIYIVLTLLADVLNALLDPRIRVK

Sequences:

>Translated_305_residues
MFGFLLRRLGIALCVAITVSVISFSLLHLSGDLATAIGGPEASSEQIEQIRVQYGLNKPLVTQYFEWLADVVRLDLGDSF
FFQESVYNLIASRLSITLGLGAMALSIALLIAIPLGVLAAVKRDTWIDRLALSIAVLGQAMPSFWFALMLIVVFSVTLKW
LPVSGNSTWAHFVMPAIALGYYATPAIMRLTRAGMLDVLNSDYIRTARAKGLRPATVLFKHALRNALIPVVALAAVEFGF
MLGGSVVIETVFSLQGIGQLAWDAIARDDFPVVQAVVLLIAVIYIVLTLLADVLNALLDPRIRVK
>Mature_305_residues
MFGFLLRRLGIALCVAITVSVISFSLLHLSGDLATAIGGPEASSEQIEQIRVQYGLNKPLVTQYFEWLADVVRLDLGDSF
FFQESVYNLIASRLSITLGLGAMALSIALLIAIPLGVLAAVKRDTWIDRLALSIAVLGQAMPSFWFALMLIVVFSVTLKW
LPVSGNSTWAHFVMPAIALGYYATPAIMRLTRAGMLDVLNSDYIRTARAKGLRPATVLFKHALRNALIPVVALAAVEFGF
MLGGSVVIETVFSLQGIGQLAWDAIARDDFPVVQAVVLLIAVIYIVLTLLADVLNALLDPRIRVK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=42.156862745098, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=38.4615384615385, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1789888, Length=307, Percent_Identity=37.4592833876222, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1787497, Length=306, Percent_Identity=35.9477124183007, Blast_Score=187, Evalue=6e-49,
Organism=Escherichia coli, GI1788504, Length=287, Percent_Identity=32.7526132404181, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1787761, Length=326, Percent_Identity=35.2760736196319, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=29.811320754717, Blast_Score=136, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33128; Mature: 33128

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFLLRRLGIALCVAITVSVISFSLLHLSGDLATAIGGPEASSEQIEQIRVQYGLNKPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCH
VTQYFEWLADVVRLDLGDSFFFQESVYNLIASRLSITLGLGAMALSIALLIAIPLGVLAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKRDTWIDRLALSIAVLGQAMPSFWFALMLIVVFSVTLKWLPVSGNSTWAHFVMPAIALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHH
YYATPAIMRLTRAGMLDVLNSDYIRTARAKGLRPATVLFKHALRNALIPVVALAAVEFGF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLGGSVVIETVFSLQGIGQLAWDAIARDDFPVVQAVVLLIAVIYIVLTLLADVLNALLDP
HHCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RIRVK
CCCCC
>Mature Secondary Structure
MFGFLLRRLGIALCVAITVSVISFSLLHLSGDLATAIGGPEASSEQIEQIRVQYGLNKPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCH
VTQYFEWLADVVRLDLGDSFFFQESVYNLIASRLSITLGLGAMALSIALLIAIPLGVLAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKRDTWIDRLALSIAVLGQAMPSFWFALMLIVVFSVTLKWLPVSGNSTWAHFVMPAIALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHH
YYATPAIMRLTRAGMLDVLNSDYIRTARAKGLRPATVLFKHALRNALIPVVALAAVEFGF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLGGSVVIETVFSLQGIGQLAWDAIARDDFPVVQAVVLLIAVIYIVLTLLADVLNALLDP
HHCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RIRVK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]