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The map label for this gene is fabA [H]

Identifier: 66045260

GI number: 66045260

Start: 2345072

End: 2345587

Strand: Reverse

Name: fabA [H]

Synonym: Psyr_2020

Alternate gene names: 66045260

Gene position: 2345587-2345072 (Counterclockwise)

Preceding gene: 66045261

Following gene: 66045259

Centisome position: 38.49

GC content: 58.91

Gene sequence:

>516_bases
ATGACCAAACAACACGCCTTTACCCGGGAAGACCTGCTGCGCTGCAGTCGTGGCGAGCTGTTCGGCCCAGGTAATGCGCA
ACTGCCCGCCCCCAACATGCTGATGGTTGATCGCATCACGCACATCAGCGACGAGGGCGGCAAGTTCGGCAAGGGTGAGT
TGGTCGCCGAACTGGATATCAATCCGGACCTGTGGTTCTTTGCCTGCCACTTCGAAGGTGATCCGGTCATGCCCGGATGC
CTGGGCCTCGACGCCATGTGGCAGCTGGTTGGCTTCTATCTTGGCTGGCAGGGCAACCCCGGCCGTGGCCGCGCCCTGGG
TTCAGGCGAAGTGAAGTTTTTCGGTCAGGTTCTGCCTACCGCCAAAAAAGTCACTTACAACATCCATATCAAGCGCGTCC
TGAAGGGCAAGCTGAACCTGGCCATCGCCGACGGTTCGGTGAGTGTCGACGGTCGCGAAATCTATACCGCCGAAGGCCTC
CGGGTCGGCGTGTTCACTTCCACTGAAAATTTCTAA

Upstream 100 bases:

>100_bases
GTAGGCTGCCGGACAGGGTCCTGGCGAAATTATCGCGCCAGGACTGGCGTTCGGGCCAGTGGCGCCACAACCTGCCGCAC
AAGATTATTGAGGAGCTCGC

Downstream 100 bases:

>100_bases
GGGTACTCGCATGCGCCGCGTCGTTATCACTGGTCTGGGTATTGTTTCCTGCTTGGGCAATGACAAAGACACCGTCACCG
CTAACCTGCGTGCTAACCGC

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MTKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITHISDEGGKFGKGELVAELDINPDLWFFACHFEGDPVMPGC
LGLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRVLKGKLNLAIADGSVSVDGREIYTAEGL
RVGVFTSTENF

Sequences:

>Translated_171_residues
MTKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITHISDEGGKFGKGELVAELDINPDLWFFACHFEGDPVMPGC
LGLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRVLKGKLNLAIADGSVSVDGREIYTAEGL
RVGVFTSTENF
>Mature_170_residues
TKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITHISDEGGKFGKGELVAELDINPDLWFFACHFEGDPVMPGCL
GLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRVLKGKLNLAIADGSVSVDGREIYTAEGLR
VGVFTSTENF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=169, Percent_Identity=67.4556213017752, Blast_Score=240, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 18746; Mature: 18615

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITHISDEGGKFGKGELVAELDI
CCCCCCCCHHHHHHCCCCCEECCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCEEEEEEC
NPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPT
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCC
AKKVTYNIHIKRVLKGKLNLAIADGSVSVDGREIYTAEGLRVGVFTSTENF
CEEEEEEEEEEEEECCEEEEEEECCEEEECCEEEEEECCEEEEEEECCCCC
>Mature Secondary Structure 
TKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITHISDEGGKFGKGELVAELDI
CCCCCCCHHHHHHCCCCCEECCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCEEEEEEC
NPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPT
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCC
AKKVTYNIHIKRVLKGKLNLAIADGSVSVDGREIYTAEGLRVGVFTSTENF
CEEEEEEEEEEEEECCEEEEEEECCEEEECCEEEEEECCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA