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The map label for this gene is luxQ [H]

Identifier: 66045261

GI number: 66045261

Start: 2345809

End: 2347746

Strand: Reverse

Name: luxQ [H]

Synonym: Psyr_2021

Alternate gene names: 66045261

Gene position: 2347746-2345809 (Counterclockwise)

Preceding gene: 66045270

Following gene: 66045260

Centisome position: 38.53

GC content: 60.53

Gene sequence:

>1938_bases
ATGAAGTTTCGGCACTGGGACATTAATACCCGCACGCAGATCATCAGCCTTGGCCCTGCCCTGTTGCTGACGGCTTTGCT
GATCAGCTTTTTTACCTTCGTACGTATTCAGGACCTGCGTCAGGAGCTCAATCACACCGGGCAACTGATCGCCAATCAAC
TGGCGACCGCGGTCGAGCCGGGCGTGACCACGGGCGATATCGAGGGGCTCAAGGCGCTGATGCGCGCCACCCTGTCCATG
CCCAGCGTTCGCTATGTGGAAATTCAGGACAGCTCCAATACCGCCGTGATCTACATAGACCAGCCGCGTGAAAACGAGCA
GCAGACCCGGCAGATGGAAGTTTTCCTCGCCCCCGTCCAACCGCAGCGCACCACCATCCACGGCAATCCCGGCGCGCCGG
CCGCAGGAAAAGGCCAACCCGCGCAGGGTGCTTCACAGAGTTATCTGGGGCGGGTTCTGGTGGGCATGTCCAGCGAAGCA
TTCAGCCGACGTCAGCAGGAGATACTGCTCAAGGCCGGCGTCCTGGCGATGGTCGCCTTGTTGTTCGCCTTTCTGCTGGC
GCGCAGCCTGGCCTTGAGCCTGTCCAGACCCATCAGCGATATGGGCGAAGCCCTCAAGGCGATTCAACAGGGCGATTACC
ACACGCCCATGCCGGTCAGCGATGACGCCGAGCTGGGCGCGCTGGCGCGGCACATCAACAACCTGGCAGAGAACCTGCAC
CGCGCCAGCCTCGAGCAGCAGCGCTCGGTGGCACAACTGATCCAGACGCGGGAAGAAGCCGAACAGGCCAACCGCGCCAA
ATCGGATTTTCTGGCCATGATGAGTCATGAGCTGCGTACCCCCATGAACGGCGTACTGGGCATGCTGCAGTTGCTGGAAA
CCACGCACATGACCCATGAGCAGAGCGAGTACGCGACGCTGGCGACCGAATCCACCGAGCATCTGCTGCGGGTCATCAAC
GACATCCTCGACTTTTCCCGCATTGAGCGCGATGCCCTGCAAATGGAAGGCATACCGTTCAACCTGGCTGAACTGGTCAG
CGCCTCGACCCACGCCTTCAACCACAGCGCCGCGCAACGCAACCTGCTGCTGGAGCTGCACATTCAGCCAGGCCTGGAGA
CCATGAACGTCATAGGCGATCCGACCCGCATTCGCCAGATTCTGGTGAACCTGATCGGCAACGCACTTAAATTCACCGAG
CGAGGCAAGGTCTGCGTGGACGCCAGGTGGGCAATGCTCGACGATGAGCGGCTGCACTTTACCTGTGCGGTACAGGACAG
CGGCATCGGTATCGACGCCGAGCGACTGGAATCGATGTTCGATGCGTTCAAGCAGGCCGACAGCTCCATTTCCAGGCGTT
ACGGCGGCACGGGGCTGGGGCTGCCGATTGCACGGACCCTGGCCGAACGCATGGGCGGCACCTTGTACGCCGAGAGCAAG
GAAGGTTCGGGCTCGTTGTTCACGCTGCAGATCCCCCTGCCCCTCTCGCGCGATGCCTCGGTGGCTATTGCCAAACCGCT
GTCGATACTCGATGCACATGGCCGGGAGCGCAGTATCCTGCTGGTCGAAGACAACCCGGTGAACCGCACGGTGGTGCAGG
CCATGTTGCGTAATCTGGGATGTGAGGTCGATATCGCCGTCGACGGGGCCGAAGCGGTGATGAAGGCACGTGCAGGCAAC
CACGCGCTGATTCTCATGGATTGCCGACTGCCGGTCATGGATGGCTACGAGGCCACCCGTCGAATCAGGCAACTTTCCGG
GCTGGAACGAATCCCAATCATTGCCCTGACAGCCAACGCGTTACAGGGGGACCGGGACGCCTGTTTGCAGGCAGGAATGG
ATGATTACCTGCCAAAGCCCTTCAAACATGCTGATTTACAGCAGGTTTTACAGCGCTGGCTGTCCTTTGAAGCACCTGCG
ACTGGCGATAAATGTTAA

Upstream 100 bases:

>100_bases
GCCTTGTGCAGCCGGACCGATTCGCGACCACCGGGCGAACAGGCATGGACGCATCAATCGAACCACCTCCGCAATGCGTT
GCGCGCGAGGCGCACAGCCG

Downstream 100 bases:

>100_bases
ATTACGGCAGTCTTGGCATCCAGATCGGCCAGCAAAATCGGCTGAATGACAAAATTCAGTGTACAGGTGTACCTTGATTT
CACCTGCGCTGTGACTTTCA

Product: response regulator receiver:ATP-binding region, ATPase-like:histidine kinase, HAMP region:histidine kinase A, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MKFRHWDINTRTQIISLGPALLLTALLISFFTFVRIQDLRQELNHTGQLIANQLATAVEPGVTTGDIEGLKALMRATLSM
PSVRYVEIQDSSNTAVIYIDQPRENEQQTRQMEVFLAPVQPQRTTIHGNPGAPAAGKGQPAQGASQSYLGRVLVGMSSEA
FSRRQQEILLKAGVLAMVALLFAFLLARSLALSLSRPISDMGEALKAIQQGDYHTPMPVSDDAELGALARHINNLAENLH
RASLEQQRSVAQLIQTREEAEQANRAKSDFLAMMSHELRTPMNGVLGMLQLLETTHMTHEQSEYATLATESTEHLLRVIN
DILDFSRIERDALQMEGIPFNLAELVSASTHAFNHSAAQRNLLLELHIQPGLETMNVIGDPTRIRQILVNLIGNALKFTE
RGKVCVDARWAMLDDERLHFTCAVQDSGIGIDAERLESMFDAFKQADSSISRRYGGTGLGLPIARTLAERMGGTLYAESK
EGSGSLFTLQIPLPLSRDASVAIAKPLSILDAHGRERSILLVEDNPVNRTVVQAMLRNLGCEVDIAVDGAEAVMKARAGN
HALILMDCRLPVMDGYEATRRIRQLSGLERIPIIALTANALQGDRDACLQAGMDDYLPKPFKHADLQQVLQRWLSFEAPA
TGDKC

Sequences:

>Translated_645_residues
MKFRHWDINTRTQIISLGPALLLTALLISFFTFVRIQDLRQELNHTGQLIANQLATAVEPGVTTGDIEGLKALMRATLSM
PSVRYVEIQDSSNTAVIYIDQPRENEQQTRQMEVFLAPVQPQRTTIHGNPGAPAAGKGQPAQGASQSYLGRVLVGMSSEA
FSRRQQEILLKAGVLAMVALLFAFLLARSLALSLSRPISDMGEALKAIQQGDYHTPMPVSDDAELGALARHINNLAENLH
RASLEQQRSVAQLIQTREEAEQANRAKSDFLAMMSHELRTPMNGVLGMLQLLETTHMTHEQSEYATLATESTEHLLRVIN
DILDFSRIERDALQMEGIPFNLAELVSASTHAFNHSAAQRNLLLELHIQPGLETMNVIGDPTRIRQILVNLIGNALKFTE
RGKVCVDARWAMLDDERLHFTCAVQDSGIGIDAERLESMFDAFKQADSSISRRYGGTGLGLPIARTLAERMGGTLYAESK
EGSGSLFTLQIPLPLSRDASVAIAKPLSILDAHGRERSILLVEDNPVNRTVVQAMLRNLGCEVDIAVDGAEAVMKARAGN
HALILMDCRLPVMDGYEATRRIRQLSGLERIPIIALTANALQGDRDACLQAGMDDYLPKPFKHADLQQVLQRWLSFEAPA
TGDKC
>Mature_645_residues
MKFRHWDINTRTQIISLGPALLLTALLISFFTFVRIQDLRQELNHTGQLIANQLATAVEPGVTTGDIEGLKALMRATLSM
PSVRYVEIQDSSNTAVIYIDQPRENEQQTRQMEVFLAPVQPQRTTIHGNPGAPAAGKGQPAQGASQSYLGRVLVGMSSEA
FSRRQQEILLKAGVLAMVALLFAFLLARSLALSLSRPISDMGEALKAIQQGDYHTPMPVSDDAELGALARHINNLAENLH
RASLEQQRSVAQLIQTREEAEQANRAKSDFLAMMSHELRTPMNGVLGMLQLLETTHMTHEQSEYATLATESTEHLLRVIN
DILDFSRIERDALQMEGIPFNLAELVSASTHAFNHSAAQRNLLLELHIQPGLETMNVIGDPTRIRQILVNLIGNALKFTE
RGKVCVDARWAMLDDERLHFTCAVQDSGIGIDAERLESMFDAFKQADSSISRRYGGTGLGLPIARTLAERMGGTLYAESK
EGSGSLFTLQIPLPLSRDASVAIAKPLSILDAHGRERSILLVEDNPVNRTVVQAMLRNLGCEVDIAVDGAEAVMKARAGN
HALILMDCRLPVMDGYEATRRIRQLSGLERIPIIALTANALQGDRDACLQAGMDDYLPKPFKHADLQQVLQRWLSFEAPA
TGDKC

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=521, Percent_Identity=31.4779270633397, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI48994928, Length=393, Percent_Identity=35.6234096692112, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1788713, Length=369, Percent_Identity=35.230352303523, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI87081816, Length=502, Percent_Identity=32.8685258964143, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=37.7118644067797, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1788393, Length=305, Percent_Identity=27.2131147540984, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=27.4193548387097, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786912, Length=262, Percent_Identity=26.7175572519084, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082128, Length=340, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786783, Length=281, Percent_Identity=25.2669039145907, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=25.8196721311475, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=254, Percent_Identity=25.9842519685039, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1790346, Length=277, Percent_Identity=27.7978339350181, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=33.6134453781513, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082012, Length=108, Percent_Identity=36.1111111111111, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790551, Length=296, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=305, Percent_Identity=24.5901639344262, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1786911, Length=114, Percent_Identity=35.9649122807018, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787894, Length=228, Percent_Identity=25, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=121, Percent_Identity=38.0165289256198, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322044, Length=161, Percent_Identity=35.4037267080745, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6323034, Length=147, Percent_Identity=31.2925170068027, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70997; Mature: 70997

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRHWDINTRTQIISLGPALLLTALLISFFTFVRIQDLRQELNHTGQLIANQLATAVEP
CCCEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVTTGDIEGLKALMRATLSMPSVRYVEIQDSSNTAVIYIDQPRENEQQTRQMEVFLAPVQ
CCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHEEEECCC
PQRTTIHGNPGAPAAGKGQPAQGASQSYLGRVLVGMSSEAFSRRQQEILLKAGVLAMVAL
CCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LFAFLLARSLALSLSRPISDMGEALKAIQQGDYHTPMPVSDDAELGALARHINNLAENLH
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RASLEQQRSVAQLIQTREEAEQANRAKSDFLAMMSHELRTPMNGVLGMLQLLETTHMTHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
QSEYATLATESTEHLLRVINDILDFSRIERDALQMEGIPFNLAELVSASTHAFNHSAAQR
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHC
NLLLELHIQPGLETMNVIGDPTRIRQILVNLIGNALKFTERGKVCVDARWAMLDDERLHF
CEEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEE
TCAVQDSGIGIDAERLESMFDAFKQADSSISRRYGGTGLGLPIARTLAERMGGTLYAESK
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECC
EGSGSLFTLQIPLPLSRDASVAIAKPLSILDAHGRERSILLVEDNPVNRTVVQAMLRNLG
CCCCCEEEEEECCCCCCCCCEEHHCCHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCC
CEVDIAVDGAEAVMKARAGNHALILMDCRLPVMDGYEATRRIRQLSGLERIPIIALTANA
CEEEEEECCHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECHH
LQGDRDACLQAGMDDYLPKPFKHADLQQVLQRWLSFEAPATGDKC
HCCCHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKFRHWDINTRTQIISLGPALLLTALLISFFTFVRIQDLRQELNHTGQLIANQLATAVEP
CCCEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVTTGDIEGLKALMRATLSMPSVRYVEIQDSSNTAVIYIDQPRENEQQTRQMEVFLAPVQ
CCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHEEEECCC
PQRTTIHGNPGAPAAGKGQPAQGASQSYLGRVLVGMSSEAFSRRQQEILLKAGVLAMVAL
CCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LFAFLLARSLALSLSRPISDMGEALKAIQQGDYHTPMPVSDDAELGALARHINNLAENLH
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RASLEQQRSVAQLIQTREEAEQANRAKSDFLAMMSHELRTPMNGVLGMLQLLETTHMTHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
QSEYATLATESTEHLLRVINDILDFSRIERDALQMEGIPFNLAELVSASTHAFNHSAAQR
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHC
NLLLELHIQPGLETMNVIGDPTRIRQILVNLIGNALKFTERGKVCVDARWAMLDDERLHF
CEEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEE
TCAVQDSGIGIDAERLESMFDAFKQADSSISRRYGGTGLGLPIARTLAERMGGTLYAESK
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECC
EGSGSLFTLQIPLPLSRDASVAIAKPLSILDAHGRERSILLVEDNPVNRTVVQAMLRNLG
CCCCCEEEEEECCCCCCCCCEEHHCCHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCC
CEVDIAVDGAEAVMKARAGNHALILMDCRLPVMDGYEATRRIRQLSGLERIPIIALTANA
CEEEEEECCHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECHH
LQGDRDACLQAGMDDYLPKPFKHADLQQVLQRWLSFEAPATGDKC
HCCCHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]