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The map label for this gene is sucC [H]

Identifier: 66045252

GI number: 66045252

Start: 2335587

End: 2336753

Strand: Direct

Name: sucC [H]

Synonym: Psyr_2012

Alternate gene names: 66045252

Gene position: 2335587-2336753 (Clockwise)

Preceding gene: 66045251

Following gene: 66045253

Centisome position: 38.33

GC content: 57.93

Gene sequence:

>1167_bases
ATGAATCTTCACGAGTATCAGGGTAAGCAGCTGTTCGCTGAGTACGGCCTGCCAGTATCCAAGGGTTACGCGGTAGACAC
CCCGGAAGCAGCAGCAGAAGCCTGCGACAAGATCGGCGGGACCGAGTGGGTCGTCAAAGCCCAGGTTCACGCAGGTGGTC
GCGGTAAAGCGGGCGGCGTAAAGCTGGTTCGCAGCAAGGAAGACGCTGCAGCGTTCGCTCAACAGTGGTTGGGCAAGCGC
CTGGTGACTTACCAGACTGACGCCAACGGTCAGCCAGTGACCAAGATCCTGGTCGAGTCCTGCACCGACATCGCCAAAGA
GCTGTATCTGGGCGCTGTGGTCGATCGTTCCAGCCGTCGTATCGTGTTCATGGCTTCCACCGAAGGTGGCGTGGACATCG
AGAAGATCGCTCACGACACTCCTGAAAAGATTCTCAAGGCCACCATCGATCCACTGGTCGGCGCTCAGCCGTTCCAGGGT
CGCGATCTGGCATTCCAGCTGGGTCTGGAAGGCAAGCAGGTCACTCAGTTCGCCAAGATCTTCACCGGTCTGGCCAAGCT
GTTCCAGGACCATGACCTGGCATTGCTGGAAGTGAACCCGCTGGTGATCAAGGCTGACGGCGATCTGCACTGCCTGGACG
CCAAGATCAACATCGACGCCAACGCCATGTACCGTCAGCCAAAGCTGAAGGGCTTCCACGATCCTTCGCAGGACGATCCT
CGCGAAGCTCACGCAGCCAAGTTCGAACTGAACTACGTTGCGCTGGAAGGCAACATCGGCTGCATGGTCAACGGTGCCGG
TCTGGCCATGGGTACCATGGACATCGTCAACCTGCATGGCGGCAAGCCTGCAAACTTCCTTGACGTTGGCGGCGGTGCCA
CCAAGGAACGCGTTACCGAAGCGTTCAAGATCATCCTGTCCGACGCCAACGTCGCTGCAGTACTGGTCAACATCTTCGGC
GGCATCGTTCGTTGCGACATGATTGCCGAAGGCATCATCGGTGCAGTGAAAGAAGTCGGCGTTAAAATCCCGGTTGTTGT
GCGCCTTGAAGGCAACAACGCTGAGCTGGGCGCTAAAGTACTGGCAGAAAGCGGTTTGAACATCATCGCTGCTACCAGCC
TGACCGACGCTGCTCAACAAGTTGTCAAAGCCGCGGAGGGCAAGTAA

Upstream 100 bases:

>100_bases
CGGCATTTGCGGAGTCCACCCGGAGTAGCGGTCACAGGTGGTGCGGCACGCTGACGTGCAGCACCGAATGCGCAGTACCT
AAACGAAGACGGTAATAAGC

Downstream 100 bases:

>100_bases
TGAGCGTCCTGATCAATAAAGACACCAAGGTTATCTGCCAGGGTTTCACTGGTTCGCAAGGTACCTTCCACTCCGAGCAA
GCCATTGCCTACGGCACCAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQGKQLFAEYGLPVSKGYAVDTPEAAAEACDKIGGTEWVVKAQVHAGGRGKAGGVKLVRSKEDAAAFAQQWLGKR
LVTYQTDANGQPVTKILVESCTDIAKELYLGAVVDRSSRRIVFMASTEGGVDIEKIAHDTPEKILKATIDPLVGAQPFQG
RDLAFQLGLEGKQVTQFAKIFTGLAKLFQDHDLALLEVNPLVIKADGDLHCLDAKINIDANAMYRQPKLKGFHDPSQDDP
REAHAAKFELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTEAFKIILSDANVAAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKIPVVVRLEGNNAELGAKVLAESGLNIIAATSLTDAAQQVVKAAEGK

Sequences:

>Translated_388_residues
MNLHEYQGKQLFAEYGLPVSKGYAVDTPEAAAEACDKIGGTEWVVKAQVHAGGRGKAGGVKLVRSKEDAAAFAQQWLGKR
LVTYQTDANGQPVTKILVESCTDIAKELYLGAVVDRSSRRIVFMASTEGGVDIEKIAHDTPEKILKATIDPLVGAQPFQG
RDLAFQLGLEGKQVTQFAKIFTGLAKLFQDHDLALLEVNPLVIKADGDLHCLDAKINIDANAMYRQPKLKGFHDPSQDDP
REAHAAKFELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTEAFKIILSDANVAAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKIPVVVRLEGNNAELGAKVLAESGLNIIAATSLTDAAQQVVKAAEGK
>Mature_388_residues
MNLHEYQGKQLFAEYGLPVSKGYAVDTPEAAAEACDKIGGTEWVVKAQVHAGGRGKAGGVKLVRSKEDAAAFAQQWLGKR
LVTYQTDANGQPVTKILVESCTDIAKELYLGAVVDRSSRRIVFMASTEGGVDIEKIAHDTPEKILKATIDPLVGAQPFQG
RDLAFQLGLEGKQVTQFAKIFTGLAKLFQDHDLALLEVNPLVIKADGDLHCLDAKINIDANAMYRQPKLKGFHDPSQDDP
REAHAAKFELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTEAFKIILSDANVAAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKIPVVVRLEGNNAELGAKVLAESGLNIIAATSLTDAAQQVVKAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=47.5826972010178, Blast_Score=354, Evalue=6e-98,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.6475195822454, Blast_Score=317, Evalue=9e-87,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=44.7513812154696, Blast_Score=301, Evalue=5e-82,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=76.2886597938144, Blast_Score=582, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=43.2569974554707, Blast_Score=323, Evalue=7e-89,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=44.6153846153846, Blast_Score=320, Evalue=6e-88,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=41.7302798982188, Blast_Score=324, Evalue=2e-89,
Organism=Drosophila melanogaster, GI21356231, Length=395, Percent_Identity=42.7848101265823, Blast_Score=304, Evalue=5e-83,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=42.2391857506361, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=42.2391857506361, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=42.3857868020305, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=42.3857868020305, Blast_Score=293, Evalue=2e-79,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41183; Mature: 41183

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQGKQLFAEYGLPVSKGYAVDTPEAAAEACDKIGGTEWVVKAQVHAGGRGKAGGV
CCCCHHCCHHHHHHHCCCCCCCEECCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KLVRSKEDAAAFAQQWLGKRLVTYQTDANGQPVTKILVESCTDIAKELYLGAVVDRSSRR
EEEECCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCE
IVFMASTEGGVDIEKIAHDTPEKILKATIDPLVGAQPFQGRDLAFQLGLEGKQVTQFAKI
EEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHH
FTGLAKLFQDHDLALLEVNPLVIKADGDLHCLDAKINIDANAMYRQPKLKGFHDPSQDDP
HHHHHHHHCCCCEEEEEECEEEEEECCCEEEEEEEEECCCHHEECCCCCCCCCCCCCCCC
REAHAAKFELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTE
CHHHHEEEEEEEEEEECCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDANVAAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKIPVVVRLEGNNAELGAKV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHH
LAESGLNIIAATSLTDAAQQVVKAAEGK
HHHCCCCEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLHEYQGKQLFAEYGLPVSKGYAVDTPEAAAEACDKIGGTEWVVKAQVHAGGRGKAGGV
CCCCHHCCHHHHHHHCCCCCCCEECCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KLVRSKEDAAAFAQQWLGKRLVTYQTDANGQPVTKILVESCTDIAKELYLGAVVDRSSRR
EEEECCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCE
IVFMASTEGGVDIEKIAHDTPEKILKATIDPLVGAQPFQGRDLAFQLGLEGKQVTQFAKI
EEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHH
FTGLAKLFQDHDLALLEVNPLVIKADGDLHCLDAKINIDANAMYRQPKLKGFHDPSQDDP
HHHHHHHHCCCCEEEEEECEEEEEECCCEEEEEEEEECCCHHEECCCCCCCCCCCCCCCC
REAHAAKFELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTE
CHHHHEEEEEEEEEEECCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDANVAAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKIPVVVRLEGNNAELGAKV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHH
LAESGLNIIAATSLTDAAQQVVKAAEGK
HHHCCCCEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA